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| Number | Title | Issue Date |
| 7459425 | Reagents for protection of peptide/proteins carbamylation in urea solutions utilizing non-ethylene-diamine like compounds The present invention generally relates to non-ethylene diamine like compounds that prevent and/or delay carbamylation of peptides. ... | 12/02/2008 |
| 7279305 | Gene, disrupted in schizophrenia A newly identified gene, DIS1 is disrupted by a (1;11)(q42.1;q14.3) translocation which segregates with schizophrenia. We have examined the genomic structure of DIS1 and found that the gene consists of 13 exons estimated to extend across at least 300 kb of DNA. Exon... | 10/09/2007 |
| D551759 | Applicator for inserting an implant | 09/25/2007 |
| 7252934 | Synergistic activation of regulatory elements by Rel proteins and a steroid receptor Interaction of Rel proteins and steroid receptors is known to result in repression of target genes. Here we describe the discovery of a new mechanism in which Rel proteins and steroid receptors act synergistically to activate a regulatory element. This mechanism is ... | 08/07/2007 |
| 7229789 | Methods and compositions for extracting proteins from cells A process is disclosed for releasing proteins from cells and/or inactivating viruses. In the process, a host cell containing a protein of interest is contacted with a solution of an effective amount of a detergent. ... | 06/12/2007 |
| 7223579 | Identification of 3-ketosteroid 9-alfa-hydroxylase genes and microorganisms blocked in 3-ketosteroid 9-alfa-hydroxylase activity The invention relates to an isolated polynucleotide sequence comprising a nucleic acid sequence encoding the amino acid sequence of KshA protein or of KshB protein, encoded by nucleotides 499–1695 of SEQ ID NO: 1 or by nucleotides 387–1427 of SEQ ID NO:2, respec... | 05/29/2007 |
| 7214706 | Chroman derivatives as estrogenic compounds The invention provides chroman compounds having Formula (1), wherein R1 is (1C–4C)alkyl, (2C–4C)alkenyl or (2C–4C)alkynyl, and independently R1 has a cis-orientation in relation to the exocyclic phenyl group at the 2-position of the skele... | 05/08/2007 |
| 7183367 | Vinyl sulphone modified polymer There is provided a polymer having a side chain of general formula (I) in which R may be any suitable alkyl, oxyalkyl, aryl or oxyaryl linking group R is preferably C1-6 alkyl (especially —CH2—), a benzene group or a group —CH2... | 02/27/2007 |
| 7141560 | Alanine 2,6-dialkoxyphenyl ester derivatives as hypnotics The present invention relates to alanine 2,6-dialkoxyphenyl ester derivatives having the general formula I The invention also relates to pharmaceutical compositions comprising said derivatives, and to the use of th... | 11/28/2006 |
| 7026304 | 2-alkylated-cyclodextrin derivatives: reversal agents for drug-induced neuromuscular block Disclosed are 2-alkylated-cyclodextrin derivatives and pharmaceutically acceptable salts thereof. The 2-alkylated-cyclodextrin derivatives are suitable for use in the reversal of drug-induced neuromuscular block. ... | 04/11/2006 |
| 6989378 | Testosterone derivative The invention is the novel androgen (7α,17β)-7-methyl-17-[(1-oxoundecyl)oxy]estr-4en-3one (MENT undecanoate). This compound distinguishes favourably from other testosterone derivatives in that it has a good solubility in oily media. It particularly exhibits a good... | 01/24/2006 |
| 6987124 | Use of serotonergic compound for a method of treatment of hot flushes in post-menopausal women The present invention relates to a method of treatment of hot flushes with a 5-HT2C receptor agonist and in particular to the use of the selective 5-HT2C receptor agonists 1-[6-chloro-5-(trifluoromethyl)-2-pyridinyl]-piperazine and (S)-(+)-3-[(... | 01/17/2006 |
| 6818441 | Vectors for improving cloning and expression in low copy number plasmids Improved vectors and related materials and methods are disclosed. ... | 11/16/2004 |
| 6818667 | Eurotinones, and derivatives thereof, processes for preparing them, and their use The present invention relates to novel compounds of the formula I in which R(1), R(2), R(3) and R(4) are, independently of each other, hydrogen or an alkyl radical. The compounds of the formula I are inhibitors of KDR ... | 11/16/2004 |
| 6777544 | Polyamide nucleic acid derivatives and agents and processes for preparing them The present invention relates to PNA derivatives which carry, at the N terminus of the PNA backbone, a phosphoryl radical. The phosphoryl radical can be, for example, a phosphate radical, or a substituted phosphoryl radical, with substituted phosphoryl derivatives c... | 08/17/2004 |
| 6720153 | Luciferase reporter bioassay of parathyroid hormone compounds This invention is directed to a bioassay for determining the functionality of parathyroid hormone compounds. More particularly, this invention is directed to a bioassay wherein the compound to be tested is added to a culture of parathyroid hormone receptor expressin... | 04/13/2004 |
| 6447996 | Galanin receptors, nucleic acids, transformed cells and uses thereof Polypeptides having galanin receptor activity, genetic material for expressing same, any recombinant cell expressing said polypeptides, and the use thereof, are disclosed.... | 09/10/2002 |
| 6291685 | Methods for the preparation of 4-hydroxybenzothiophene The present invention is concerned with a novel process for the preparation of the hydroxybenzothiophene of formula I ##STR1## comprising cyclocarbonylation of a compound of formula II ##STR2## wherein Y is as defined in the specification, followed by sap... | 09/18/2001 |
| 6239151 | Compounds as inhibitor of tumor necrosis factor alpha release The invention provides hydrazine derivatives of the formula ##STR1## wherein R1 is lower alkyl, lower alkenyl, lower cycloalkyl, lower cycloalkyl-lower alkyl, aryl or aryl-lower alkyl; R2 is an acyl group derived from an -, &#... | 05/29/2001 |
| 6239296 | Process for a phenylthiobutyl-isoquinoline and intermediates therefor Intermediate compounds useful for making phenylthiobutyl-isoquinoline compounds of formula ##STR1##... | 05/29/2001 |
