...that after Walter Hunt patented the safety pin in 1849, he sold the rights to it for $400?
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| Number | Title | Issue Date |
| 5514401 | Supercritical fluid extraction of cholesterol from liquid egg yolk A method for extraction of cholesterol from untreated yolk with supercritical carbon dioxide. The supercritical carbon dioxide extraction of cholesterol from the liquid egg yolk is performed in the presence or absence of cosolvents or other agents enhanci... | 05/07/1996 |
| 5470731 | Coated transplant and method for making same Transplants are coated with an insoluble immunological barrier membrane. The membrane can comprise a non-cytotoxic first layer of agarose and cationic amino acid polymer and a non-cytotoxic second layer chemically bonded to said first layer, the second la... | 11/28/1995 |
| 5468511 | Method for removal of cholesterol and fat from liquid egg yolk with recovery of free cholesterol as a by-product A method for extraction and removal of cholesterol from untreated liquid egg yolk with simultaneous production of cholesterol as a by-product. The removal of cholesterol from the untreated liquid egg yolk is achieved by the extraction of cholesterol into ... | 11/21/1995 |
| 5432319 | Furnace for heat treatment of dental products in an inert atmosphere A high temperature furnace for heat treatment of various products, and for sintering. One of the uses is for preparing dental products such as dental crowns, bridges, implants and the like. The main component of the furnace is a cup-shaped quartz vessel, ... | 07/11/1995 |
| 5429821 | Non-fibrogenic high mannuronate alginate coated transplants, processes for their manufacture, and methods for their use A transplant comprising a core of a viable, physiologically active cells coated with a non-fibrogenic alkaline earth metal alginate free from fibrogenic amounts of fucose, sulfate, phloroglucinol and protein moieties, having a mannuronate to guluronate mo... | 07/04/1995 |
| 5429925 | Method for immunodiagnostic detection of dioxins at low concentrations A method is described for the use of monoclonal antibodies in a sensitive immunoassay for halogenated dioxins and dibenzofurans in industrial samples which contain impurities. Appropriate sample preparation and selective enzyme amplification of the immuno... | 07/04/1995 |
| 5391965 | Gas discharge ignition device and method using high frequency and high power to ignite a uniform electrode surface area A device and method for establishing and maintaining a gas discharge extending essentially through the entire space between electrodes which face each other. The gas discharge is obtained by providing on at least one of the surfaces of the electrodes faci... | 02/21/1995 |
| 5385708 | Determination of ultra low levels of mercury A highly specific and sensitive electrode for the determination of ultra-low levels of mercury and an analytical system based on such electrode. The electrode is a glassy carbon electrode spin-coated with a monolayer of a highly sensitive reagent for the ... | 01/31/1995 |
| 5374726 | Process for preparing 10-deazaaminopterins and 5,10-and 8,10-dideazaaminopterins from pteroic dicarboxylic acid diesters A process is provided for the preparation of 10-deazaaminopterins and 5,10- and 8,10-dideazaaminopterins starting from the corresponding homoterephthalic acid diester coupling the corresponding dicarboxylic acid diester having the formula: ##STR1## ... | 12/20/1994 |
| 5366726 | Suppression of Pneumocystis carinii using aerosolized pentamidine treatment A method of preventing clinically manifest Pneumocystis carinii pneumonia in immunocompromised humans is provided wherein an aerosol of pentamidine is administered to the patient in a manner which delivers the aerosol to the patient's alveoli. Also provid... | 11/22/1994 |
| 5364615 | Prophylaxis of pneumocystis carinii with aerosilized pentamidine A method of preventing clinically manifest Pneumocystis carinii pneumonia in immunocompromised humans is provided wherein an aerosol of pentamidine is administered to the patient in a manner which delivers the aerosol to the patient's alveoli. Also provid... | 11/15/1994 |
| 5354751 | Heteroaroyl 10-deazaamino-pterine compounds and use for rheumatoid arthritis There is disclosed certain heteroaroyl 10-deazaaminopterin and 5, 10 and 8, 10 di deazaminopterin compounds and their use for treatment of rheumatoid arthritis and related diseases and preparative process. Also disclosed are 10 alkenyl-(and alkynyl) 10-deazami... | 10/11/1994 |
| 5334528 | Monoclonal antibodies to cyclodiene insecticides and method for detecting the same Methods are described for making specific monoclonal antibodies useful for detection of cyclodienes in foods and environmental samples. Monoclonal antibodies specifically reactive with cyclodienes can detect accumulated pesticides in food, tissue or envir... | 08/02/1994 |
| 5330741 | Long-wavelength water soluble chlorin photosensitizers useful for photodynamic therapy and diagnosis of tumors Novel photosensitizers useful for photodynamic therapy and diagnosis of tumors. Photosensitizers are derived from chlorophyll-a of photosynthetic plants and algae, possess long wavelength absorption between 600 and 800 nm, are stable, and water soluble. A... | 07/19/1994 |
| 5328985 | Recombinant streptavidin-protein chimeras useful for conjugation of molecules in the immune system A novel recombinant streptavidin-protein A chimeric protein which allows conjugation of antibody molecules with biological materials. The chimeric protein is efficiently expressed in Escherichia coli and is purified by simple procedures. The purified chim... | 07/12/1994 |
| 5312839 | Compounds and method for protection of cells and tissues from irreversible injury due to lactic acidosis Compounds and a method useful for protection of tissue cells in a mammalian body from irreversible damages due to lactic acidosis caused by oxygen deficiency. The protection is achieved by administering a compound having a cell membrane permeability and/o... | 05/17/1994 |
| 5292638 | Method of determining functional estrogen receptors for prognosis of cancer A method and assay for determination of functionality of steroid receptors present in breast or other tumors. The method is useful for determination of cancer responsiveness to hormonal therapy by establishing a correlation between functioning estrogen re... | 03/08/1994 |
| 5286488 | Method for topical treatment of lesions associated with viral infections The use of the active ingredient present in the juice obtained from the green hull of the kukui nut for use as an antiviral pharmaceutical agent. This active ingredient is particularly useful in the topical treatment of viral infections, such as herpes si... | 02/15/1994 |
| 5269149 | Method for long range transcontinental and transoceanic transport of fresh chilled meat A method for long range transcontinental or transoceanic transport of fresh chilled meat. The method concerns a transport of vacuum packaged chilled beef, pork or lamb meat or poultry or fish in refrigerated containers wherein one part of the container is... | 12/14/1993 |
| 5248295 | Bioelectrode seal An iontophoretic bioelectrode includes an enclosure forming upper sheet of material having a generally planar outer section circumscribing a raised central section which defines an interior compartment. A compliant, resilient and sticky raised barrier is ... | 09/28/1993 |
| 5236412 | Rehydratable product and method of preparation thereof A hydratable iontophoretic bioelectrode includes a plurality of layers of material capable of absorbing and holding an ionized fluid when placed in contact with the fluid. Adjacent layers are maintained at least partially out of contact from one another b... | 08/17/1993 |
| 5224989 | Film-forming dispersion for a protective coating of drug and food containing articles and objects A film-forming dispersion for the formation of protective coatings on shaped drug and food articles which comprises 1 to 25 weight percent of acetylester of oxidized starch and 0.8 to 8 weight percent of triethylcitrate.... | 07/06/1993 |
| 5223530 | Arylcycloalkanepolyalkylamine ligands Novel arylcycloalkanepolyalkylamines useful as anti-psychotic, anti-ischemia, anti-stroke, anti-dementia and anti-convulsant agents. These arylcycloalkanepolyalkylamines are selective high-affinity ligands to the sigma binding-sites containing three basic... | 06/29/1993 |
| 5213798 | Antiviral agent derived from the hull of the kukui nut The use of the active ingredient present in the juice obtained from the green hull of the kukui nut for use as an antiviral pharmaceutical agent. This active ingredient is particularly useful in the topical treatment of viral infections, such as herpes si... | 05/25/1993 |
| 5090153 | Insect monitoring system A lightweight, durable convenient, practical, versatile and efficient insect monitoring system and trap for capturing crawling and flying adult insect or larvae. The trap is a two-piece snap-on plastic unit which contains an adhesive to trap the insects a... | 02/25/1992 |
| 5087242 | Hydratable bioelectrode A hydratable iontophoretic bioelectrode includes a layer of material for absorbing and holding an ionized fluid when placed in contact with the fluid. A conductive sheet of material is positioned in contact with one side of the layer of material and is co... | 02/11/1992 |
| 5086054 | Novel arylcycloalkanepolyalkylamines Novel arylcycloalkanepolyalkylamines useful as anti-psychotic, anti-ischemia, anti-stroke, anti-dementia and anti-convulsant agents. These arylcycloalkanepolyalkylamines are selective high-affinity ligands to the sigma binding-sites containing three basic... | 02/04/1992 |
| 5075210 | Preservation of the heart for transplantation A novel method for long-term preservation of heart for transplantation. The heart is perfused first with a preservation solution containing essentially pyruvate, inorganic salts providing ions to retain the cell action potential and optionally a protein, ... | 12/24/1991 |
| 5066578 | Long-term preservation of organs for transplantation A novel method for preservation of organs for transplantation, wherein the organ to be transplanted is first perfused with a preservation solution containing essentially pyruvate, inorganic salts providing ions to retain the cell action potential and opti... | 11/19/1991 |
| 5053238 | Method for shell removal from hard boiled eggs A novel method for shell removal from hard-boiled eggs using chemical methods or, in alternative, a combination of chemical with mechanical methods. The acid or alkali is used to soften the egg shell prior to mechanical peeling or to dissolve the shell co... | 10/01/1991 |
| 5043165 | Novel liposome composition for sustained release of steroidal drugs This invention relates to a novel, non-conventional liposome formulation for the sustained release and delivery of steroids. The formulation provides prolonged release of the drug, improved therapeutic ratio, lower toxicity, reduced systemic side effects ... | 08/27/1991 |
| 5032582 | Method for treating fungal infections with amphotericin B/cholesterol sulfate composition An amphotericin B composition containing particles of amphotericin B and cholesterol sulfate, in a molar ratio of between about 1:1 to 1:4. The particles, when stored in lyophilized form and reconstituted in an aqueous suspension, have particle sizes pred... | 07/16/1991 |
| 5030442 | Non-crystalline minoxidil composition An aqueous, noncrystalline minoxidil composition for topical use which has significantly improved flux of the drug through human cadaver skin. The composition contains minoxidil complexed with an amphipathic compound, oleic acid and with pharmaceutically ... | 07/09/1991 |
| 4958452 | Animal identification ear tag assembly A new and improved animal identification ear devices assembly consisting of a novel rivet, a flexible base having rib-like reinforcement ramps, an animal ear tag and an applicator tool. The flexible base allows the rivet and the tag to move forward when m... | 09/25/1990 |
| 4906476 | Novel liposome composition for sustained release of steroidal drugs in lungs This invention relates to a novel, non-conventional liposome formulation for the sustained release and delivery of steroids. The formulation provides prolonged release of the drug, improved therapeutic ratio, lower toxicity, reduced systemic side effects ... | 03/06/1990 |
| 4613675 | Phosphorus containing 1-cyclohexene-1,2-dicarboxamides Substituted 1-cyclohexene-1,2-dicarboxamides, synthesis thereof, intermediates therefor, and the use of said compounds for the control of weeds.... | 09/23/1986 |
| 4590282 | Pest control agents Dioxolane and benzodioxin derivatives, intermediates therefor, synthesis thereof, and the use of the compounds for the control of pests.... | 05/20/1986 |
| 4500737 | Compositions Novel substituted cycloalkanediones and their use for the control of weeds.... | 02/19/1985 |
| 4499271 | 3-Phosphinyloxy-4-(substituted phenoxy)alkenoic acid esters 3-Phosphinyloxy-4-substituted phenoxy alkenoic acid esters, derivatives thereof, and the use thereof for the control of weeds.... | 02/12/1985 |
| 4497965 | Substituted phenoxyalkanetriones Substituted phenoxyalkanetriones and the use thereof for the control of weeds.... | 02/05/1985 |