Did You Know...
...that after Parker Brothers executives turned down the game of Monopoly because it had "52 fundamental errors" (including taking too long to play), a copy of the game wound up in the home of the company president who stayed up until 1 a.m. to finish playing it? He was so impressed by the game that the next day he wrote to inventor Charles Darrow and offered to buy it!
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| Number | Title | Issue Date |
| 6083711 | Proteases compositions capable of binding to said site, and methods of use thereof Novel herpes viral protease crystalline structures are identified which have an active site formed by the three amino acids Ser, His and His. Also disclosed are methods of identifying inhibitors of these proteases and/or active sites.... | 07/04/2000 |
| 5969184 | Amide compounds The present invention is directed to the novel intermediate compounds of the formula: ##STR1## wherein, interalia, R4 is a substituted phenyl or an optionally substituted napthyl derivative.... | 10/19/1999 |
| 5917043 | 4-aryl-5-pyrimidine imiazole substituted compounds The present invention relates to a novel method for synthesizing imidazole derivatives having 4-aryl, 5-pyrimidine heterocyclic rings using a novel cycloaddition reaction.... | 06/29/1999 |
| 5908853 | Compositions The present invention involves the novel use of H2 and H3 agonists, as erectogenic agents in the treatment of male and female sexual dysfunction in an animal, including humans. The H2 and H3 agonists may be admi... | 06/01/1999 |
| 5897025 | Tablet dispenser A container for dispensing tablets in which the dispensing opening and/or a dispensing passage upstream of the dispensing opening is constricted such that a tablet is releasably retained with part of the tablet projecting outside of the dispensing opening... | 04/27/1999 |
| 5886044 | IL-8 receptor antagonists This invention relates to the novel use of phenyl ureas in the treatment of disease states mediated by the chemokine, Interleukin-8 (IL-8).... | 03/23/1999 |
| 5885629 | Stable, optically clear compositions Stable aqueous compositions of biologically active oils for the preparation of optically clear products for use in human or animal healthcare, for example beverages, are prepared by a process comprising: (a) mixing 0.001-2.0% w/w of a biologically active ... | 03/23/1999 |
| 5886215 | 2-acetoxymethyl-4-halo-butyl-1-yl acetates The present invention provides a process for the synthesis of penciclovir and famciclovir by 9-substituting 2-amino-6-chloropurine (ACP) with an appropriate side chain precursor, followed by conversion of the 6-chloro moiety to a hydroxy moiety (i.e. to f... | 03/23/1999 |
| 5869660 | Process of preparing imidazole compounds Novel 1,4,5-substituted imidazole compounds and compositions for use in therapy as cytokine inhibitors.... | 02/09/1999 |
| 5866162 | Pharmaceutical composition containing a drug/ଲ-cyclodextrin complex in combination with an acid-base couple A pharmaceutical composition for oral consumption in liquid form is provided, characterized in that the composition contains a drug, preferably a lipophilic NSAID, complexed to ଲ-cyclodextrin in a formulation also containing an acid-base couple, pre... | 02/02/1999 |
| 5866581 | Penciclovir for the treatment of post therapeutic neuralgia A method for the treatment of PHN in mammals, including humans, which method comprises administering an effective amount of a compound of formula (A), or a pharmaceutically acceptable salt thereof. ##STR1##... | 02/02/1999 |
| 5864036 | Substituted imidazole compounds Novel 1,4,5-substituted imidazole compounds and compositions for use in therapy as cytokine inhibitors.... | 01/26/1999 |
| 5861172 | Pharmaceutical formulations of compacted granulates of ଲ-lactam antibiotics The present invention discloses tablet formulations, produced by dry roller compaction comprising compacted granulates of a mixture of a medicament and an intra-granular disintegrant. The granulates are compacted together into a tablet with an extra-granu... | 01/19/1999 |
| 5851550 | Pharmaceutical formulations of compacted granulates of ଲ-Lactam antibiotics The present invention discloses tablet formulations, produced by dry roller compaction comprising compacted granulates of a mixture of a medicament and an intra-granular disintegrant. The granulates are compacted together into a tablet with an extra-granu... | 12/22/1998 |
| 5840763 | Treatment of a latent infection of herpes viruses A method for the treatment of latent infection of herpesviruses in mammals, including humans, which method comprises administering to the mammal in need of such treatment, an effective amount of a compound of formula (A): ##STR1## or a bioprecursor, ... | 11/24/1998 |
| 5824696 | Medicaments The present invention relates to the use of an angiotensin II receptor antagonist in the manufacture of a medicament for the treatment of chronic inflammatory disease states.... | 10/20/1998 |
| 5811549 | Process of preparing imidazole compounds Novel 1,4,5-substituted imidazole compounds and compositions for use in therapy as cytokine inhibitors.... | 09/22/1998 |
