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Attorney: DeBenedictis; Karen


Number of patents: 16
Last date: May 08, 2012

NumberTitleIssue Date
8173634Polymorphic form of 1-(4-{1-[(E)-4-cyclohexyl-3-trifluoromethyl-benzyloxyimino]-ethyl}-2-ethyl-benzyl)-azetidine-3-carboxylic
This invention relates to a novel crystalline form (Form A) of 1-(4-{1-[(E)-4-cyclohexyl-3-trifluoromethyl-benzyloxyimino]-ethyl}-2-ethyl-benzyl)-azetidine-3-carboxylic acid (Compound I), to pharmaceutical compositions comprising this crystalline form, to processes ...
05/08/2012
7985323Purification process
Purification process for the preparation of the allylamine pharmaceutical terbinafine of formula I in free base form or acid addition salt form, by distilling crude terbinafine base, preferably by short path distillation, e...
07/26/2011
7939519Immunosuppresant compounds and compositions
The present invention relates to immunosuppressant, process for their production, their uses and pharmaceutical compositions containing them. The invention provides a novel class of compounds useful in the treatment or prevention of diseases or disorders mediated by...
05/10/2011
7910626Use of S1P receptor agonists in heart diseases
The invention relates to the use of a sphingosine-1-phosphate receptor agonist in the treatment of heart diseases. ...
03/22/2011
7902175Aminopropanol derivatives
Compounds of formula I: wherein R1, R2, n and m are as defined in the specification, processes for their production, their uses and pharmaceutical compositions containing them. ...
03/08/2011
75248495-arylpyrimidines as anticancer agents
This invention relates to certain 5-arylpyrimidine compounds or a pharmaceutically acceptable salt thereof, and compositions containing said compounds or a pharmaceutically acceptable salt thereof, wherein said compounds are anti-cancer agents useful for the treatme...
04/28/2009
7521552Process for preparation of substituted amino alcohols
There is provided a process for the preparation of substituted amino alcohols HO—(CH2)n—NR1R2 from haloalcohols HO—(CH2)n—X, where X is Cl, Br or I, by reaction with an amine HNR1R
04/21/2009
7250433Tetrazole and oxadiazolone substituted β-amino acid derivatives
This invention relates to novel tetrazole and oxadiazalone β-amino acids derivatives of the formula wherein G is wherein R1 through R4
07/31/2007
7101886Phenylalkyl and pyridylalkyl piperazine derivatives
This invention relates to compounds of the formula 1 wherein R1, R3, R4, X1, and X2 are defined as in the specification, pharmaceutical compositions containi...
09/05/2006
7064147Amino acids with affinity for the α-2-delta-protein
This invention relates to certain β-amino acids that bind to the alpha-2-delta (α2δ) subunit of a calcium channel. These compounds and their pharmaceutically acceptable salts are useful in the treatment of a variety of psychiatric, pain and other disorders. ...
06/20/2006
7030267Cycloproply β-amino acid derivatives
This invention relates to novel cyclopropyl β-amino acids derivatives of the formula wherein R1 through R4 are defined as in the specification, pharmaceutical compositions containing them and thei...
04/18/2006
7026505Method of treating tinnitus
The invention relates to a method of treating tinnitus by administering an alpha2delta ligand such as, for example, a compound of Formula and pharmaceutically acceptable salts thereof, wherein R1 is hydrogen ...
04/11/2006
7022678Pregabalin lactose conjugates
In accordance with the present invention, there is provided pregabalin lactose conjugate compounds. Also provided as part of the present invention is a novel method of central nervous system disorders or diseases including seizure disorders, pain, depression,...
04/04/2006
6891059Asymmetric synthesis of pregabalin
This invention provides a method of making (S)-(+)-3-(aminomethyl)-5-methylhexanoic acid (pregabalin) or a salt thereof via an asymmetric hydrogenation synthesis. Pregabalin is useful for the treatment and prevention of seizure disorders, pain, and psychotic disorde...
05/10/2005
6642398Mono-and disubstituted 3-propyl gamma-aminobutyric acids
The instant invention is a series of novel mono- and disubstituted 3-propyl gamma aminobutyric acids of Formula I ##STR1## The compounds are useful as therapeutic agents in the treatment of epilepsy, faintness attacks, hypokinesia, cranial disorders, ...
11/04/2003
6635673Cyclic amino acids and derivatives thereof useful as pharmaceutical agents
The invention is a novel series of cyclic amino acids which are useful in the treatment of epilepsy, faintness attacks, neurodegenerative disorders, depression, anxiety, panic, pain, neuropathological disorders, gastrointestinal disorders such as irritabl...
10/21/2003
 
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