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"During my service in the United States Congress, I took the initiative in creating the Internet."
Al Gore ; The basis for the later misquote by US Republicans that Gore had "invented" the Internet. Gore was the leading political champion of the modern-day Internet.
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| Number | Title | Issue Date |
| 7919610 | Yeast bacterial two-hybrid system and methods of use thereof A combined yeast/bacterial two-hybrid system is disclosed. ... | 04/05/2011 |
| 7916892 | Method and apparatus for processing mail to obtain image data of contents A method and apparatus for processing mail is provided. Mail is placed into an input bin having a conveyor that conveys the mail towards a feeder. the feeder serially feeds the envelopes by engaging the lead envelope in the stack of mail and displacing the lead enve... | 03/29/2011 |
| 7891833 | Rechargeable flashlight and battery assembly for single-handed intermittent and continuous operation A rechargeable flashlight is also provided. The flashlight includes a housing having a battery compartment and a light source adjacent a first end of the housing. A rechargeable lithium-ion battery provides power for the flashlight. A controller circuit serially con... | 02/22/2011 |
| 7883436 | Bi-directional tensioner An assembly for maintaining tension in a drive belt features a housing mounted on a base. The housing contains a biasing element that exerts torque on the housing to bias the housing in a radial direction. A lever arm is connected to the housing and rotates with the... | 02/08/2011 |
| 7879823 | Topical anti-cancer compositions and methods of use thereof Described are skin-care compositions containing non denatured soy products and optionally other anti-cancer or anti-aging agents. The compositions can be applied topically to reduce the risk of UV-induced cutaneous tumors. ... | 02/01/2011 |
| 7862825 | Method of controlling tight blood glucose by somatostatin receptor antagonists The present disclosure provides methods and uses for controlling tight blood glucose levels in a subject comprising administering an effective amount of a somatostatin inhibitor. The present disclosure provides methods and uses for treating or preventing hypoglycemi... | 01/04/2011 |
| 7861844 | Method and apparatus for sorting items A method and apparatus are provided for sorting items to a plurality of sort destinations. The items are loaded onto one of a plurality of independently controlled delivery vehicles. The delivery vehicles follow a track that guides the delivery vehicles to the sort ... | 01/04/2011 |
| 7861684 | Compression ignition engine and method for controlling same An engine having improved combustion characteristics is provided. The engine includes a fuel injection system that is variable between two operational states. In the first operating state, the fuel injectors provide a fuel spray having first spray pattern characteri... | 01/04/2011 |
| 7842460 | Method for assessing proteolytic enzyme activity using ubiquitin fusion substrate Methods and kits for assessing proteolytic enzyme activity and a modulator's effect thereof employ a Ubiquitin or Ubiquitin-like Protein and a signal producing structure. The corresponding fusion polynucleotide is employed for production of transgenic cells, plants ... | 11/30/2010 |
| 7840394 | Method for generating a 3D earth model A method is provided for generating an invertible 3D hydrodynamic earth model suitable for defining target characteristics of a subsurface area formed by a plurality of formations and comprising drilling positions of potential and real wells. The method comprises co... | 11/23/2010 |
| 7837996 | Materials and methods for treatment of hepatitis C The present invention relates to materials and methods for treatment of hepatitis C. More closely, the invention relates to human monoclonal antibodies against HCV E1 antigen, to a reagent comprising such antibodies, and to vaccine compositions comprising such antib... | 11/23/2010 |
| 7837582 | Bi-directional belt tensioner An assembly for maintaining tension in a drive belt features a housing mounted on a base. The housing contains a biasing element that exerts torque on the housing to bias the housing in a radial direction. A lever arm is connected to the housing and rotates with the... | 11/23/2010 |
| 7825842 | Digital sigma-delta modulators A digital sigma-delta modulator (100) for modulating a digital input signal (x) is described. The digital sigma-delta modulator (100) comprises a quantizer (115) for quantizing an input signal (s) and producing a quantized output signal (y) at a... | 11/02/2010 |
| 7820789 | Mutant pneumolysin proteins The invention relates to immunogenic compositions comprising mutant Streptococcus pneumoniae pneumolysin proteins. The invention further relates to such proteins and nucleic acids encoding these proteins. In particular embodiments, the invention is directed t... | 10/26/2010 |
| 7820384 | Methods and compositions for protein expression and purification Methods for enhancing expression levels and secretion of heterologous fusion proteins in a host cell are disclosed. ... | 10/26/2010 |
| 7816334 | Materials and methods relating to immune responses to fusion proteins The invention provides nucleic acid construct and nucleic acid expression vectors directing the expression of a fusion protein consisting of a disease peptide antigen and a first domain of FrC of tetanus toxin. The invention provides nucleic acid (DNA) vaccines for ... | 10/19/2010 |
| 7816085 | Method for in vitro molecular evolution of protein function The invention provides a method for generating a polynucleotide sequence or population of sequences from parent single stranded polynucleotide sequences encoding one or more protein motifs, comprising the steps of a) providing single stranded DNA constituting plus a... | 10/19/2010 |
| 7807418 | Method for producing hybrid polyketide synthases A hybrid type I polyketide synthase gene typically containing a starter module and a plurality of heterologous extender modules is used to synthesise novel polyketides. It is preferably under the control of type II polypolyketide synthase promoter e.g. act I or S... | 10/05/2010 |
| 7794930 | Snail, a new marker for tumour invasion and target protein of new antitumoral compounds The Snail transcription factor has been identified as a repressor of the expression of E-cadherin. The expression of Snail induces invasive and metastatic capacity in tumour cells. This invention presents: a new target protein, Snail, for the identification of new a... | 09/14/2010 |
| 7781568 | Anti-mullerian inhibiting substance type II receptor (MISIIR) immunoconjugates to detect and treat cancer Compositions and methods for detecting and treating cancers expressing Mullerian inhibiting substance Type II receptor (MISIIR) are provided. ... | 08/24/2010 |
| 7770882 | Apparatus and method for processing sheets A method and apparatus are provided for processing sets of sheets. The apparatus includes a frame, a hopper for moving a stack of sheets, a pre-singulator for separating a portion of a sheet from the stack, a sheet peeler for peeling part of a pre-singulated sheet f... | 08/10/2010 |
| 7767925 | System and method for automated document processing A method and apparatus for processing mail is provided. A stack of mail is placed in an input bin in a feeder module. A feeder serially feeds the envelopes into a transport path. The envelopes are then examined to determine if the contents are qualified for extracti... | 08/03/2010 |
| 7750136 | Modified bouganin proteins, cytotoxins and methods and uses thereof The invention provides modified forms of bouganin protein having biological activity and a reduced propensity to activate human T cells as compared to the non-modified bouganin protein. The invention also provides T-cell epitope peptides of bouganin, and modified T-... | 07/06/2010 |
| 7745485 | Compositions and methods for identifying agents which modulate PTEN function and PI-3 kinase pathways Methods are provided for the identification, biochemical characterization and therapeutic use of agents which impact PTEN, p53, PI-kinase and AKT mediated cellular signaling. ... | 06/29/2010 |
| 7731020 | Conveyor with attachments A conveyor assembly is provided, which includes a link belt formed of a plurality of overlapping belt links. A plurality of engagement elements are attached to the link belt to form an upper surface. In one embodiment, the link belt includes a plurality of apertures... | 06/08/2010 |
| 7723564 | Compositions and methods for modulation of KSR1 and KSR2 interactions Materials and methods for identifying agents which modulate KSR mediated signal transduction are provided. ... | 05/25/2010 |
| 7723269 | Process for selecting anti-angiogenesis antibody fragments, anti-angiogenesis antibody fragments thus obtained and their use The invention describes a process for filter selection of anti-angiogenesis antibody fragments from a large combinatorial repertoire; the invention further relates to the anti-angiogenesis antibody fragments thus obtained. ... | 05/25/2010 |
| 7723109 | Expression of spider silk proteins The present invention relates to the fields of molecular biology and plant biology. Specifically, the invention is directed to the methods for expressing spider silk proteins in plants and the synthesis and purification of spider silk proteins therefrom. ... | 05/25/2010 |
| 7706914 | Method and apparatus for processing mail to obtain image data of contents A method and apparatus for processing mail is provided. Mail is placed into an input bin having a conveyor that conveys the mail towards a feeder. The feeder serially feeds the envelopes by engaging the lead envelope in the stack of mail and displacing the lead enve... | 04/27/2010 |
| 7705198 | KSR2 knockout mice and methods of use thereof A transgenic non-human animal with a homologous disruption of the KSR-2 gene is disclosed. Methods for using transgenic mice so generated to screen for agents that effect cellular metabolism are also provided. ... | 04/27/2010 |
| 7705022 | IDO inhibitors and methods of use thereof Novel indoleamine 2,3-dioxygenase (IDO) inhibitors, compositions comprising the same, and methods of use thereof are disclosed. ... | 04/27/2010 |
| 7704736 | Compositions for the derivation of germ cells from stem cells and methods of use thereof Compositions and methods are provided for the reproducible derivation of germ cells and oocytes and spermatogonia therefrom. Also provide are methods of use of the same in reproductive and therapeutic cloning protocols. ... | 04/27/2010 |
| 7696306 | Compositions and methods for preventing or treating cancer The present invention relates to a MUC1 cytoplasmic tail peptide or portion thereof. These peptides are useful for inducing an immune response to MUC1-expressing tumor cells and thus for preventing or treating cancer. ... | 04/13/2010 |
| 7683236 | Enhanced production of cloned mammals by zona pellucida-free homologous mammalian embryo aggregation Compositions and methods are provided for the efficient and reproducible generation of clone animals of all developmental stages. Also provided are methods of use of the same in reproductive and therapeutic cloning protocols. ... | 03/23/2010 |
| 7667093 | Site-specific recombination system to manipulate the plastid genome of higher plants A site specific recombination system and methods of use thereof are disclosed for manipulating the genome of higher plants. ... | 02/23/2010 |
| 7662939 | Molecular determinants of tropism and virulence in enteroviruses Recombinant enteroviruses for use as vaccines or vectors, which are modified in tropism or virulence, are disclosed. Also disclosed are DNA constructs comprising enterovirus-derived molecular determinants of tropism or virulence for use in targeting genes of interes... | 02/16/2010 |
| 7662551 | Synthesis of hybrid polynucleotide molecules using single-stranded polynucleotide molecules A method to make libraries of hybrid polynucleotide molecules of two parental polynucleotide molecules utilizing single-stranded DNA was invented. Example of the method comprises several steps: (i) preparation of two single-stranded polynucleotide molecules comprisi... | 02/16/2010 |
| 7655413 | Methods and compositions for enhanced protein expression and purification Methods for enhancing expression levels and secretion of heterologous fusion proteins in a host cell are disclosed. ... | 02/02/2010 |
| PP20694 | plant named ‘Red Dragon’ A new and distinct cultivar of Corylus plant named ‘Red Dragon,’ characterized by its outwardly spreading plant habit, twisting stems, rich dark burgundy-colored leaves, burgundy color of the catkins and leaf buds, and resistance to eastern filbert blight... | 02/02/2010 |
| 7645601 | Methods and means for modulating PGE synthase activity Isolated PGE synthase, provided from encoding nucleic acid. Methods of production and use. Assays for modulators, especially inhibitors, of PGE synthase activity. ... | 01/12/2010 |
