Bizarre Patents
Mouthguard made at least partially from an edible candy
A mouthguard includes a U-shaped upper bite plate which removably fits over upper teeth of a person, with the entire upper bite plate being made from a soft, deformable and edible gummi candy.
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 7563578 | Method for in vitro molecular evolution of protein function The invention provides a method for generating a polynucleotide sequence or population of sequences from parent single stranded polynucleotide sequences encoding one or more protein motifs, comprising the steps of a) providing sing... | 07/21/2009 |
| 7560252 | Borrelidin-producing polyketide synthase and its use The present invention relates to the biosynthesis of polyketides and derives from the cloning of nucleic acids encoding a polyketide synthase and other associated proteins involved in the synthesis of the polyketide borrelidin. Materials and methods including enzyme... | 07/14/2009 |
| 7316914 | Methods and materials relating to gene expression An expression cassette for expressing a nucleic acid of interest derived from the regulatory region of the methylenomycin gene cluster of the SCP1 plasmid of Streptomyces coelicolor A3(2), and related materials and methods. ... | 01/08/2008 |
| 7291336 | Compositions and methods for enhancing immune responses mediated by antigen-presenting cells Molecular adjuvants are disclosed comprising an antigen presenting cell-targeting ligand functionally linked to an immunogen, e.g. tumor associated antigens, bacterial or viral antigens, etc. Methods are disclosed for delivery of these molecular adjuvants to patient... | 11/06/2007 |
| 7238524 | Prostate cancer cell lines Novel human prostate cancer-associated neuroendocrine (NE)-like cell lines are provided that were derived via a process that resembles clinical androgen ablation therapy for advanced prostate cancer. ... | 07/03/2007 |
| 7230158 | derived frigida gene conferring late flowering Disclosed are isolated nucleic acids obtainable from the FRI locus of plants which encode polypeptides capable of specifically altering, particularly delaying, the flowering time of a plant into which the nucleic acid is introduced. One preferred embodiment is the F... | 06/12/2007 |
| 7217860 | Site-specific recombination system to manipulate the plastid genome of higher plants A site-specific recombination system and methods of use thereof are disclosed for manipulating the plastid genome of higher plants. ... | 05/15/2007 |
| 7217854 | Enhanced transgene expression by co-expression with a suppressor of post-transcriptional gene silencing (PTGS) Disclosed are a variety of methods for achieving enhanced expression from a target nucleotide sequence in a plant e.g. comprising the step of transiently introducing into a tissue of a plant (e.g. a leaf) a first nucleic acid comprising the target nucleotide sequenc... | 05/15/2007 |
| 7192733 | Methods and means for modulating PGE synthase activity Isolated PGE synthase, provided from encoding nucleic acid. Methods of production and use. Assays for modulators, especially inhibitors, of PGE synthase activity. ... | 03/20/2007 |
| 7186884 | Isolated plant gene encoding a β amyrin synthase Disclosed are isolated β-amyrin synthase-encoding cDNA and genomic nucleic acids, which are involved in saponin synthesis. Also provided are complementary sequences, vectors, transformed host cells, transformed plants, and methods for influencing or affecting trite... | 03/06/2007 |
| 7166704 | Antibodies immunologically specific for PD2, a protein that is amplified and overexpressed in pancreatic cancer A human nucleic acid, PD2, its encoded protein and antibodies immunologically specific thereto are disclosed herein. The expression of the disclosed PD2 gene plays a key role in the regulation of differentiation and in the maintenance of the neoplastic state. The PD... | 01/23/2007 |
| 7153655 | Method for in vitro molecular evolution of protein function involving the use of exonuclease enzyme and two populations of parent polynucleotide sequence The present invention relates to a method for in vitro evolution of protein function. In particular, the method relates to the shuffling of nucleotide segments obtained from exonuclease digestion. The present inventors have shown that polynucleotide fragments derive... | 12/26/2006 |
| 7105657 | Compositions and methods for inhibiting pancreatic cancer metastasis Methods are provided for the inhibition of metastasis of cancer cells expressing MUC4, metastatic pancreatic cancer cells. ... | 09/12/2006 |
| 7094533 | Therapeutic and diagnostic applications of prostatic acid phosphatase in prostate cancer Presented is a therapeutic method to treat prostate carcinomas in mammals comprising the administration of cellular PAcP protein. Also presented is a method to diagnose androgen-insensitive prostate carcinomas by determining the expression level of cellular PAcP in ... | 08/22/2006 |
| 7084267 | Promoter regions of the mouse and human telomerase RNA component genes The present invention relates to the identification of the genomic promoter region of the human and mouse telomerase RNA gene. Telomerase activity is necessary for the unrestricted proliferative capacity of many human cancers. It is proposed that mutation or dysregu... | 08/01/2006 |
| 7083941 | Compositions and methods for gender sorting A yeast based transactivation assay for gender sorting is disclosed. ... | 08/01/2006 |
| 7078188 | MUC17 encoding nucleic acid sequences, polypeptides, antibodies and methods of use thereof Disclosed herein are human MUC17-encoding nucleotide sequences, proteins, antibodies, and methods for use thereof. ... | 07/18/2006 |
| 7078180 | Methods and compositions useful for diagnosis, staging, and treatment of cancers and tumors Methods, compositions and kits which employ one or more ZEB specific detection reagents for detection and localization of ZEB associated molecules in tumor cells are disclosed. Also provided are methods for determining stage and progression of cancer in a mammal bas... | 07/18/2006 |
| 7074554 | Antibodies specific for NEBR1 and methods of use thereof Materials and methods are provided to inhibit HIV replication in targeted host cells. ... | 07/11/2006 |
| 7063847 | Compositions and methods for enhancing immune responses mediated by antigen-presenting cells Molecular adjuvants are disclosed comprising an antigen presenting cell-targeting ligand linked to an immunogen, e.g. tumor associated antigens, bacterial or viral antigens. The ligand and the immunogen are linked via a cleavable linker such as a protease-sensitive ... | 06/20/2006 |
| 7060461 | Methods and compositions for protein expression and purification Methods for enhancing expression levels and secretion of heterologous fusion proteins in a host cell are disclosed. ... | 06/13/2006 |
| 7060452 | Assay method for measurement of net cholesterol flux The present invention relates to an assay for determining net cholesterol flux from lipid loaded cells in the presence of an acceptor (e.g., serum). The present invention also relates to a method for evaluating efficacy of a therapeutic agent for stimulating or inhi... | 06/13/2006 |
| 7052859 | MUCIN 4 expression as a marker for pancreatic cancer Methods are provided for the diagnosis of pancreatic cancer. ... | 05/30/2006 |
| 7045682 | Methods and means for modification of plant flowering characteristics Provided are isolated nucleic acid molecules which comprise VRN1 nucleotide sequences, which encode a polypeptide which is capable of specifically altering the vernalisation response of a plant into which the nucleic acid is introduced and expressed. Examples includ... | 05/16/2006 |
| 7037656 | Methods and compositions for identifying ligands for nuclear receptors A yeast-based system and methods of use therefore are provided for identifying new molecules which activate nuclear receptors in a ligand-dependent fashion. In a preferred embodiment, a method is provided utilizing ecdysone receptor, USP and GRIP I encoding expressi... | 05/02/2006 |
| 7031844 | Cluster analysis of genetic microarray images A method for determining relative incidence of a binding substance within two biological samples is provided. The two samples are labeled with luminescent materials having different chromatic properties. An image of the luminescent materials upon a binding site of a... | 04/18/2006 |
| 7029863 | Cell culture system for determining the cholesterol efflux potential for serum The present invention relates to a cell culture system to provide a tool for assessing the potential of a patient's serum for preventing the accumulation of cholesterol in arteries (i.e. serum efflux potential) that leads to atherosclerosis and to screen new drug co... | 04/18/2006 |
| 7026330 | Methods for treatment of acute lymphocytic leukemia Methods for treating patients having an early B cell derived acute lymphoblastic leukemia with rapamycin or a derivative thereof are provided. Also provided are methods for treating patients having an early B cell derived acute lymphoblastic leukemia with rapamycin ... | 04/11/2006 |
| 7008921 | Materials and methods relating to endothelial cell growth inhibitors Proteolytic enzymes are involved in generation of a number of endogenous angiogenesis inhibitors and it has been shown that urokinase-activated plasmin can process plasminogen to release an angiogenesis inhibitor, K1–5 (protease-activated kringles 1–5). However,... | 03/07/2006 |
| 6623983 | Apparatus and methods for capture and analysis of particulate entities Apparatus and methods are disclosed which facilitate immobilization of magnetically labelled particulate entities, e.g., cells, preferably in a defined pattern, on a collection surface via binding between specific binding pair members, as an aid to partic... | 09/23/2003 |
| 6124374 | Antimicrobial denture adhesive and cleanser compositions An antimicrobial denture adhesive, denture cleansing creme or denture soaking or brushing composition comprises a combination of 8-hydroxyquinoline (or its salt) and at least one copper(II) salt. The composition fights denture stomatitis by inhibiting Can... | 09/26/2000 |
| 5989611 | Agent for increasing the keeping quality of slaughtered-animal carcasses The invention concerns an agent for enhancing the keeping quality of bodies of slaughtered animals, parts of bodies of slaughtered animals, and hamburger patties, a process for the use thereof, and bodies of slaughtered animals, parts of bodies of slaught... | 11/23/1999 |
| 5858187 | Apparatus and method for performing electrodynamic focusing on a microchip A microchip device includes a focusing channel, in which an electric field strength established in the focusing channel is controlled relative to an electric field strength established in a material transport channel segment to spatially focus the materia... | 01/12/1999 |
| 5840708 | Administration of oligonucleotides antisense to dopamine receptor MRNA for diagnosis and treatment of Neurological pathologies A method and pharmaceutical preparation are provided for diagnosing and treating pathological conditions related to a dopamine receptor abnormality. The method comprises administering to a patient having such a pathological condition an oligonucleotide an... | 11/24/1998 |
| 5645081 | Method of treating tissue damage and apparatus for same The invention disclosed is a method of treating tissue damage comprising applying a negative pressure to a wound sufficient in time and magnitude to promote tissue migration and thus facilitate closure of the wound. The method is applicable to wounds, bur... | 07/08/1997 |
| 4601979 | Process for preparing human insulin or B-30 esters thereof Human insulin or B-30 esters thereof are prepared by reacting an insulin derivative of the formula ##STR1## wherein R is hydroxyl or an amino acid radical being different from threonine, and -A- and -B- represent the A- and B-chains with the same ... | 07/22/1986 |
