An armor with rollers is provided that enables a user to move in all positions by rolling on a hard and smooth surface while constantly varying his bearing points on the ground.
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| Number | Title | Issue Date |
| 8119806 | Cicletanine derivatives A compound having the structure wherein X is selected from the group consisting of: a bond, —NHCH2(CH2)nCH2OC(O)—, —CH2NHC(O)CH2 | 02/21/2012 |
| 8106034 | Angiotensin II receptor antagonists A compound having the structure wherein R is an angiotensin receptor blocking group Y is —(CR1R20)1-7R5, or —C(O)(CR1R | 01/31/2012 |
| 8080543 | Pyridine derivative potassium channel inhibitors The present invention relates to pyridine substituted ethanol compounds and derivatives thereof having the structure (I) useful as potassium channel inhibitors to treat cardiac arrhythmias, and the like. ... | 12/20/2011 |
| 8076359 | Renin inhibitors The present invention relates to disubstituted piperidinyl renin inhibitor compounds having the structure (Formula I) and their use in treating cardiovascular events and renal insufficiency. ... | 12/13/2011 |
| 8067607 | Potassium channel inhibitors The present invention relates to pyridin-3-yl pyridin-3-amine compounds and derivatives thereof having the structure formula (I) useful as potassium channel inhibitors to treat cardiac arrhythmias, and the like. ... | 11/29/2011 |
| 8053455 | Angiotensin II receptor antagonists A compound having the structure wherein R is an angiotensin receptor antagonist active group, Y is selected from the group consisting of ... | 11/08/2011 |
| 8030359 | Polymer formulations of CETP inhibitors A pharmaceutical composition comprises (a) a CETP inhibiting compound, or a pharmaceutically acceptable salt thereof; (b) a concentration-enhancing polymer, and (c) optionally one or more surfactants; wherein the compound has the structure shown as Formula I below. ... | 10/04/2011 |
| 8030332 | Potassium channel inhibitors The present invention relates to dipyridin-3-ylmethoxy compounds and derivatives thereof having the structure I useful as potassium channel inhibitors to treat cardiac arrhythmias, and the like. ... | 10/04/2011 |
| 7947664 | Angiotensin II receptor antagonists A compound having the structure wherein R is an angiotensin receptor antagonist active group, Y is selected from the group consisting of and ... | 05/24/2011 |
| 7935727 | CETP inhibitors Compounds having a biphenyl group substituted with a phenyl or heteroaromatic group, as shown in Formula I, including pharmaceutically acceptable salts of the compounds, are CETP inhibitors, and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and f... | 05/03/2011 |
| 7915271 | 1,3-oxazolidin-2-one derivatives useful as CETP inhibitors Compounds having the structure of Formula I, including pharmaceutically acceptable salts of the compounds, are CETP inhibitors, and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis. The compounds have 3... | 03/29/2011 |
| 7915252 | Sulfonyl compounds as inhibitors of 11-beta-hydroxysteroid dehydrogenase-1 Sulfonyl derivatives of structural formula I are selective inhibitors of the 11β-hydroxysteroid dehydrogenase-1. The compounds are useful for the treatment of diabetes, such as noninsulin-dependent diabetes (NIDDM), hyperglycemia, obesity, insulin resistance, dysli... | 03/29/2011 |
| 7910592 | CETP inhibitors Compounds having the structure of Formula (I), including pharmaceutically acceptable salts of the compounds, are CETP inhibitors and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis. In the compounds of... | 03/22/2011 |
| 7906521 | Quinazoline potassium channel inhibitors The present invention relates to compounds useful as potassium channel inhibitors to treat cardiac arrhythmias, and the like. ... | 03/15/2011 |
| 7879839 | Potassium channel inhibitors The present invention relates to compounds having the structure useful as potassium channel inhibitors to treat cardiac arrhythmias, and the like. ... | 02/01/2011 |
| 7863307 | Process for synthesizing a CETP inhibitor An efficient process is disclosed for producing a compound that is an inhibitor of CETP. The last step of the process is the coupling of an oxazolidinone derivative with a biphenyl moiety to provide a compound of formula (I). In a specific embodiment of this synthes... | 01/04/2011 |
| 7825131 | Quinoline potassium channel inhibitors The present invention relates to compounds having the structure (I) useful as potassium channel inhibitors to treat cardiac arrhythmias, and the like. ... | 11/02/2010 |
| 7781457 | Isoquinolinone potassium channel inhibitors The present invention relates to compounds having the structure formula (I) useful as potassium channel inhibitors to treat cardiac arrhythmias, and the like. ... | 08/24/2010 |
| 7781426 | CETP inhibitors Compounds having the structure of Formula (I), including pharmaceutically acceptable salts of the compounds, are CETP inhibitors, and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis. In the compounds o... | 08/24/2010 |
| 7741322 | Isoquinolinone potassium channel inhibitors The present invention relates to compounds having the structure (I) useful as potassium channel inhibitors to treat cardiac arrhythmias, and the like. ... | 06/22/2010 |
| 7737295 | CETP inhibitors Compounds of Formula I, including pharmaceutically acceptable salts of the compounds, are CETP inhibitors, and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis. In the compounds of Formula 1, A1 | 06/15/2010 |
| 7723352 | Isoquinolinone potassium channel inhibitors The present invention relates to compounds having the structure (I) useful as potassium channel inhibitors to treat cardiac arrhythmias, and the like. ... | 05/25/2010 |
| 7709476 | Isoquinolinone potassium channel inhibitors The present invention relates to compounds having the structure (I) useful as potassium channel inhibitors to treat cardiac arrhythmias, and the like. ... | 05/04/2010 |
| 7704988 | Anti-hypercholesterolemic compounds This invention provides cholesterol absorption inhibitors of Formula I: and the pharmaceutically acceptable salts and esters thereof. The compounds are useful for lowering plasma cholesterol levels, particularly LDL cholest... | 04/27/2010 |
| 7696339 | Nucleic acid encoding monkey QRFP There are provided non-human primate and rat GPR103 genes and proteins and a compound evaluation method employing the genes or proteins. There are also provided highly useful novel ligands for functional analysis of the GPR103 genes and proteins and for the compound... | 04/13/2010 |
| 7696177 | Anti-hypercholesterolemic compounds This invention provides cholesterol absorption inhibitors of Formula (I), and the pharmaceutically acceptable salts and esters thereof. The compounds are useful for lowering plasma cholesterol levels, particularly LDL cholesterol, and for treating and preventing ath... | 04/13/2010 |
| 7692017 | Quinoline potassium channel inhibitors The present invention relates to compounds having the structure (I) useful as potassium channel inhibitors to treat cardiac arrhythmias, and the like. ... | 04/06/2010 |
| 7691879 | Isoquinoline potassium channel inhibitors The present invention relates to compounds having the structure (I) useful as potassium channel inhibitors to treat cardiac arrhythmias, and the like. ... | 04/06/2010 |
| 7659408 | Pyrazole carboxamides as inhibitors of 11-β-hydroxysteroid dehydrogenase-1 Pyrazole carboxamides of structural formula I are selective inhibitors of the 11β-hydroxysteroid dehydrogenase-1. The compounds are useful for the treatment of diabetes, such as noninsulin-dependent diabetes (NIDDM), hyperglycemia, obesity, insulin resistance, dysl... | 02/09/2010 |
| 7652049 | CETP inhibitors Compounds having the structures of Formula I, including pharmaceutically acceptable salts of the compounds, are CETP inhibitors, and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis: ... | 01/26/2010 |
| 7629372 | Compounds for the treatment of dyslipidemia and other lipid disorders A class of compounds having Formula I and pharmaceutically acceptable salts thereof are useful as therapeutic compounds, particularly in the treatment of hyperlipidemia, hypercholesterolemia, dyslipidemia, and other lipid disorders, and in delaying the onset of or r... | 12/08/2009 |
| 7622449 | Anti-hypercholesterolemic compounds This invention provides cholesterol absorption inhibitors of Formula I: and the pharmaceutically acceptable salts and esters thereof. The compounds are useful for lowering plasma cholesterol levels, particularly LDL cholest... | 11/24/2009 |
| 7618994 | Fluoro substituted cycloalkanoindoles, compositions containing such compounds and methods of treatment Fluoro substituted cycloalkanoindole derivatives are antagonists of prostaglandins, and as such are useful for the treatment of prostaglandin mediated diseases. ... | 11/17/2009 |
| 7618979 | Pyridopyrrolizine and pyridoindolizine derivatives Pyridopyrrolizine and pyridoindolizine derivatives are prostaglandin receptor antagonists useful for the treatment of prostaglandin-mediated diseases such as allergic rhinitis, nasal congestion and asthma. ... | 11/17/2009 |
| 7598243 | Heterocyclic cyclopentyl tetrahydroisoquinoline and tetrahydropyridopyridine modulators of chemokine receptor activity The present invention is directed to compounds of the formula I: Wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, X, n and the br... | 10/06/2009 |
| 7589085 | Tetrahydropyran heterocyclic cyclopentyl heteroaryl modulators of chemokine receptor activity The present invention is further directed to compounds of the formulas: (I) (II) (wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R15, R16 | 09/15/2009 |
| 7579331 | Method of improved diuresis in individuals with impaired renal function Disclosed is a pharmaceutical composition comprising a therapeutically effective amount of KW-3902, or a salt, ester, amide, metabolite, or prodrug thereof, and a non-adenosine modifying diuretic. Also disclosed are methods of inducing a diuretic effect in an animal... | 08/25/2009 |
| 7576118 | Asymmetric hydrogenation process The present invention provides an asymmetric hydrogenation process for the preparation of chiral cycloalkanoindole DP receptor antagonists in high enantiomeric excess. ... | 08/18/2009 |
| 7569589 | Potassium channel inhibitors The present invention relates to compounds having the structure useful as potassium channel inhibitors to treat cardiac arrhythmias, and the like. ... | 08/04/2009 |
| 7566726 | 3,3-disubstituted tetrahydropyranyl cyclopentyl amide modulators of chemokine receptor activity (wherein n, R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R15, R16, R17, R18, Y a... | 07/28/2009 |