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Patent No. 5926857

Armor With Rollers

An armor with rollers is provided that enables a user to move in all positions by rolling on a hard and smooth surface while constantly varying his bearing points on the ground.

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Attorney: Daniel; Mark R.


Number of patents: 116
Last date: February 21, 2012

1      
NumberTitleIssue Date
8119806Cicletanine derivatives
A compound having the structure wherein X is selected from the group consisting of: a bond, —NHCH2(CH2)nCH2OC(O)—, —CH2NHC(O)CH2
02/21/2012
8106034Angiotensin II receptor antagonists
A compound having the structure wherein R is an angiotensin receptor blocking group Y is —(CR1R20)1-7R5, or —C(O)(CR1R
01/31/2012
8080543Pyridine derivative potassium channel inhibitors
The present invention relates to pyridine substituted ethanol compounds and derivatives thereof having the structure (I) useful as potassium channel inhibitors to treat cardiac arrhythmias, and the like. ...
12/20/2011
8076359Renin inhibitors
The present invention relates to disubstituted piperidinyl renin inhibitor compounds having the structure (Formula I) and their use in treating cardiovascular events and renal insufficiency. ...
12/13/2011
8067607Potassium channel inhibitors
The present invention relates to pyridin-3-yl pyridin-3-amine compounds and derivatives thereof having the structure formula (I) useful as potassium channel inhibitors to treat cardiac arrhythmias, and the like. ...
11/29/2011
8053455Angiotensin II receptor antagonists
A compound having the structure wherein R is an angiotensin receptor antagonist active group, Y is selected from the group consisting of ...
11/08/2011
8030359Polymer formulations of CETP inhibitors
A pharmaceutical composition comprises (a) a CETP inhibiting compound, or a pharmaceutically acceptable salt thereof; (b) a concentration-enhancing polymer, and (c) optionally one or more surfactants; wherein the compound has the structure shown as Formula I below. ...
10/04/2011
8030332Potassium channel inhibitors
The present invention relates to dipyridin-3-ylmethoxy compounds and derivatives thereof having the structure I useful as potassium channel inhibitors to treat cardiac arrhythmias, and the like. ...
10/04/2011
7947664Angiotensin II receptor antagonists
A compound having the structure wherein R is an angiotensin receptor antagonist active group, Y is selected from the group consisting of and ...
05/24/2011
7935727CETP inhibitors
Compounds having a biphenyl group substituted with a phenyl or heteroaromatic group, as shown in Formula I, including pharmaceutically acceptable salts of the compounds, are CETP inhibitors, and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and f...
05/03/2011
79152711,3-oxazolidin-2-one derivatives useful as CETP inhibitors
Compounds having the structure of Formula I, including pharmaceutically acceptable salts of the compounds, are CETP inhibitors, and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis. The compounds have 3...
03/29/2011
7915252Sulfonyl compounds as inhibitors of 11-beta-hydroxysteroid dehydrogenase-1
Sulfonyl derivatives of structural formula I are selective inhibitors of the 11β-hydroxysteroid dehydrogenase-1. The compounds are useful for the treatment of diabetes, such as noninsulin-dependent diabetes (NIDDM), hyperglycemia, obesity, insulin resistance, dysli...
03/29/2011
7910592CETP inhibitors
Compounds having the structure of Formula (I), including pharmaceutically acceptable salts of the compounds, are CETP inhibitors and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis. In the compounds of...
03/22/2011
7906521Quinazoline potassium channel inhibitors
The present invention relates to compounds useful as potassium channel inhibitors to treat cardiac arrhythmias, and the like. ...
03/15/2011
7879839Potassium channel inhibitors
The present invention relates to compounds having the structure useful as potassium channel inhibitors to treat cardiac arrhythmias, and the like. ...
02/01/2011
7863307Process for synthesizing a CETP inhibitor
An efficient process is disclosed for producing a compound that is an inhibitor of CETP. The last step of the process is the coupling of an oxazolidinone derivative with a biphenyl moiety to provide a compound of formula (I). In a specific embodiment of this synthes...
01/04/2011
7825131Quinoline potassium channel inhibitors
The present invention relates to compounds having the structure (I) useful as potassium channel inhibitors to treat cardiac arrhythmias, and the like. ...
11/02/2010
7781457Isoquinolinone potassium channel inhibitors
The present invention relates to compounds having the structure formula (I) useful as potassium channel inhibitors to treat cardiac arrhythmias, and the like. ...
08/24/2010
7781426CETP inhibitors
Compounds having the structure of Formula (I), including pharmaceutically acceptable salts of the compounds, are CETP inhibitors, and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis. In the compounds o...
08/24/2010
7741322Isoquinolinone potassium channel inhibitors
The present invention relates to compounds having the structure (I) useful as potassium channel inhibitors to treat cardiac arrhythmias, and the like. ...
06/22/2010
7737295CETP inhibitors
Compounds of Formula I, including pharmaceutically acceptable salts of the compounds, are CETP inhibitors, and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis. In the compounds of Formula 1, A1
06/15/2010
7723352Isoquinolinone potassium channel inhibitors
The present invention relates to compounds having the structure (I) useful as potassium channel inhibitors to treat cardiac arrhythmias, and the like. ...
05/25/2010
7709476Isoquinolinone potassium channel inhibitors
The present invention relates to compounds having the structure (I) useful as potassium channel inhibitors to treat cardiac arrhythmias, and the like. ...
05/04/2010
7704988Anti-hypercholesterolemic compounds
This invention provides cholesterol absorption inhibitors of Formula I: and the pharmaceutically acceptable salts and esters thereof. The compounds are useful for lowering plasma cholesterol levels, particularly LDL cholest...
04/27/2010
7696339Nucleic acid encoding monkey QRFP
There are provided non-human primate and rat GPR103 genes and proteins and a compound evaluation method employing the genes or proteins. There are also provided highly useful novel ligands for functional analysis of the GPR103 genes and proteins and for the compound...
04/13/2010
7696177Anti-hypercholesterolemic compounds
This invention provides cholesterol absorption inhibitors of Formula (I), and the pharmaceutically acceptable salts and esters thereof. The compounds are useful for lowering plasma cholesterol levels, particularly LDL cholesterol, and for treating and preventing ath...
04/13/2010
7692017Quinoline potassium channel inhibitors
The present invention relates to compounds having the structure (I) useful as potassium channel inhibitors to treat cardiac arrhythmias, and the like. ...
04/06/2010
7691879Isoquinoline potassium channel inhibitors
The present invention relates to compounds having the structure (I) useful as potassium channel inhibitors to treat cardiac arrhythmias, and the like. ...
04/06/2010
7659408Pyrazole carboxamides as inhibitors of 11-β-hydroxysteroid dehydrogenase-1
Pyrazole carboxamides of structural formula I are selective inhibitors of the 11β-hydroxysteroid dehydrogenase-1. The compounds are useful for the treatment of diabetes, such as noninsulin-dependent diabetes (NIDDM), hyperglycemia, obesity, insulin resistance, dysl...
02/09/2010
7652049CETP inhibitors
Compounds having the structures of Formula I, including pharmaceutically acceptable salts of the compounds, are CETP inhibitors, and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis: ...
01/26/2010
7629372Compounds for the treatment of dyslipidemia and other lipid disorders
A class of compounds having Formula I and pharmaceutically acceptable salts thereof are useful as therapeutic compounds, particularly in the treatment of hyperlipidemia, hypercholesterolemia, dyslipidemia, and other lipid disorders, and in delaying the onset of or r...
12/08/2009
7622449Anti-hypercholesterolemic compounds
This invention provides cholesterol absorption inhibitors of Formula I: and the pharmaceutically acceptable salts and esters thereof. The compounds are useful for lowering plasma cholesterol levels, particularly LDL cholest...
11/24/2009
7618994Fluoro substituted cycloalkanoindoles, compositions containing such compounds and methods of treatment
Fluoro substituted cycloalkanoindole derivatives are antagonists of prostaglandins, and as such are useful for the treatment of prostaglandin mediated diseases. ...
11/17/2009
7618979Pyridopyrrolizine and pyridoindolizine derivatives
Pyridopyrrolizine and pyridoindolizine derivatives are prostaglandin receptor antagonists useful for the treatment of prostaglandin-mediated diseases such as allergic rhinitis, nasal congestion and asthma. ...
11/17/2009
7598243Heterocyclic cyclopentyl tetrahydroisoquinoline and tetrahydropyridopyridine modulators of chemokine receptor activity
The present invention is directed to compounds of the formula I: Wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, X, n and the br...
10/06/2009
7589085Tetrahydropyran heterocyclic cyclopentyl heteroaryl modulators of chemokine receptor activity
The present invention is further directed to compounds of the formulas: (I) (II) (wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R15, R16
09/15/2009
7579331Method of improved diuresis in individuals with impaired renal function
Disclosed is a pharmaceutical composition comprising a therapeutically effective amount of KW-3902, or a salt, ester, amide, metabolite, or prodrug thereof, and a non-adenosine modifying diuretic. Also disclosed are methods of inducing a diuretic effect in an animal...
08/25/2009
7576118Asymmetric hydrogenation process
The present invention provides an asymmetric hydrogenation process for the preparation of chiral cycloalkanoindole DP receptor antagonists in high enantiomeric excess. ...
08/18/2009
7569589Potassium channel inhibitors
The present invention relates to compounds having the structure useful as potassium channel inhibitors to treat cardiac arrhythmias, and the like. ...
08/04/2009
75667263,3-disubstituted tetrahydropyranyl cyclopentyl amide modulators of chemokine receptor activity
(wherein n, R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R15, R16, R17, R18, Y a...
07/28/2009
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