...that several people are credited with the invention of the flush toilet? Most people have heard of Thomas Crapper (1837-1910), the sanitary engineer who invented the valve-and-siphon arrangement that made the modern toilet possible. Another claimant to "the throne" was British inventor Alexander Cumming who patented a toilet in 1775. Then there's a nameless Minoan (a native of ancient Crete) who lived 4,000 years ago who supposedly was ahead of his time and created the first flush toilet!
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| Number | Title | Issue Date |
| 6258815 | Specific immunophilin ligands as antiasthmatics and immunosuppressants The novel specific immunophilin ligands of the general formula I have an antiasthmatic and immunosuppressive action and are suitable for the preparation of drugs. ##STR1##... | 07/10/2001 |
| 6235468 | Method for characterising variability in telomere DNA by PCR A method of characterizing a test sample of genomic DNA which method comprises contacting the test sample with type specific primer to prime selectively, within a telomere repeat array, internal repeat units of that type, and extending the type specific p... | 05/22/2001 |
| 6113917 | Modified polypeptides for enhanced immunogenicity A recombinant polypeptide comprising a polypeptide which has added thereto a glycoxyl-phosphatidylinositol anchor structure, said polypeptide demonstrating a greater immune response than the corresponding polypeptide without the anchor. The polypeptide ma... | 09/05/2000 |
| 6106805 | Diagnostic composition containing an LH-RH antagonist for hysteroscopy The invention relates to a diagnostic composition for improving the effectiveness of hysteroscopy, characterized in that it contains an LH-RH antagonist, in particular cetrorelix. The composition is envisaged for use prior to hysteroscopy and/or for prepa... | 08/22/2000 |
| 6015814 | Quinazoline derivative The invention concerns derivatives of the formula wherein n is 1, 2 or 3 and each R2 is independently halogeno; and R1 is amino-(2-4C)alkylamino, (1-4C)alkylamino, (1-4C)alkylamino-(2-4C)alkylamino,di-[(1-4C)alkyl]amino-(2-4C) alkyla... | 01/18/2000 |
| 6013489 | Cloning and expression of DNA encoding a ripening form of a polypeptide having rhamnogalacturonase activity The invention relates to isolation of an Aspergillus gene encoding rhamnogalacturonase (RG-ase) and the construction of recombinant Aspergillus strains with overexpression of RG-ase. These strains can be used for the commercial production of RG-ase. RG-as... | 01/11/2000 |
| 6004764 | Method of identifying compounds that regulate the binding of M. tuberculosis sigF to M. tuberculosis orfX sigF is a gene that controls M. tuberculosis latency. A diagnostic test for latent tuberculosis involves detecting M. tuberculosis sigF in clinical specimens. Two genes orfX and orfY regulate sigF expression and sigF activity. M. tuberculosis sigF, orfX, ... | 12/21/1999 |
| 5996830 | Fuel tank cap A fuel tank cap structure with reduced casing body weight and improved dimensional accuracy is disclosed. The casing body of the fuel tank cap has a valve chamber, in which a positive pressure valve and a negative pressure valve are received. The casing b... | 12/07/1999 |
| 5981202 | Two-dimensional solid phase assay A method for assaying a substance is provided in which an optical image is obtained from spots of light emitted from a chemiluminescent material capable of undergoing a luminescent reaction. The method comprises: (a) a step of distributing solid particles... | 11/09/1999 |
| 5980501 | Reservoirs and delivery devices A passive reservoir for medicament in the form of a plastics bag 1, has a hanging eyelet 2 at its upper end and a lower outlet nozzle 3. The plastics bag 1 has bottom corners 4,5, the left-hand right-angled corner 5 of which encapsulates a data carrier me... | 11/09/1999 |
| 5982564 | Objective lens driving apparatus An objective lens holder that holds an objective lens that directs a laser beam onto a disk is formed of a permanent magnet. Yokes are arranged at the periphery of the objective lens holder, with a focus coil and tracking coil fixed to them. One end of a ... | 11/09/1999 |
| 5959178 | Modification of lignin synthesis in plants The biosynthesis of lignin in plants is regulated by insertion into the plant genome by altering the plant's ability to synthesise the enzyme O-methyl transferase, an enzyme involved in the lignin biosynthetic pathway. Production of O-methyl-transferase m... | 09/28/1999 |
| 5932574 | Quinazoline derivatives The invention concerns quinazoline derivatives of formula wherein n is 1, 2 or 3 and each R2 is independently halogeno; and R1 is di-(1-4C)alkyl!amino-(2-4C)alkoxy, pryolidin-1-yl-(2-4C)alkoxy,piperidino-(2-4C)alkoxy, morpholi... | 08/03/1999 |
| 5933649 | Method and device for controlling a CPU stop clock interrupt A method and device for controlling a CPU stop clock interrupt of a computer system. The device includes an idle detector and a control processor. A CPU having a stop clock interrupt mode receives a stop clock interrupt signal and sets up and clears the s... | 08/03/1999 |
| 5921255 | Oral cleansing article and method of cleaning teeth with the same An oral hygiene article adapted to be received as a whole within a mouth so that the article can thereby be manipulated with the tongue to dislodge foreign particles, promote salivary excretion, drag bacterial plaque, and massage the gums. The article inc... | 07/13/1999 |
| 5913010 | Information storage medium, recording method used therefor, and reproducing apparatus Data on multiple stories or scenes are recorded on a recording medium so as to reduce the physical distance moved by a pickup at playback time and to suppress breaks or disturbances in reproduced video. A multi-scene program having a plurality of optional... | 06/15/1999 |
| 5912339 | Oligonucleoside alkyl or arylphosphonate derivatives capable of crosslinking with or cleaving nucleic acids A composition for inactivating a target nucleic acid which comprises an oligonucleoside alkyl or arylphosphonate analogue which is complementary to the sequence of the target nucleic acid and includes a functional group which reacts with the target nuclei... | 06/15/1999 |
| 5902847 | Coating composition A coating composition prepared by mixing an organic solvent based coating composition with (1) a silicone compound having organofunctional group and hydrolyzable group in one molecule and containing a specified silicon structural unit, or (2) a silicone c... | 05/11/1999 |
| 5858051 | Method of manufacturing optical waveguide A method of manufacturing an optical waveguide comprises a first step of laminating, on one major surface of a first glass material, a second glass material to a desired thickness, the second glass material having optical characteristics different from th... | 01/12/1999 |
| 5854420 | Maize acetyl CoA carboxylase encoding DNA clones Clones are disclosed comprising at least part of a DNA sequence of a gene encoding maize acetyl CoA carboxylase, or a sequence showing substantial homology therewith, flanked by heterologous DNA. DNA from such clones may be used to isolate similar sequenc... | 12/29/1998 |
| 5851050 | Hydraulic closure system for a motor vehicle A hydraulic closure system is disclosed for use in a motor vehicle that enables automatic opening and closing, as well as manual closing, of a closure pivotably mounted to an opening frame defining a closure opening in the motor vehicle. The system includ... | 12/22/1998 |
| 5822235 | Rectifying transfer gate circuit A rectifying transfer gate circuit includes first and second field effect transistors and one diode. The source of the first field effect transistor is coupled to a first input node and the gate thereof is coupled to a second input node. Meanwhile, the so... | 10/13/1998 |
| 5808034 | Plant gene construct comprising male flower specific promoters Male sterility is imparted to a plant by a cascade of gene sequences which expresses a protein which disrupts the biosynthesis of viable pollen. Expression of the disrupter protein is restricted to male parts of the plant by an upstream promoter sequence ... | 09/15/1998 |
| 5797496 | Method for the utilization of ash from coal-fired plants A method for the utilization of ash from coal-fired plants, in which openss ash is drawn off when it is dry for further use. According to one embodiment of the invention, the open-pass ash is used as a raw material and fuel in cement production. Accordin... | 08/25/1998 |
| 5732889 | Electromagnetic fuel injection valve assembly A fuel injection valve assembly has a construction less expensive in production and applicable for automated assembling. A cylindrical stem portion of a movable core is movably arranged within a movable core guide bore with opposing the rear end thereof w... | 03/31/1998 |
| 5724941 | Malfunction diagnosis device of an internal combustion engine controller An air conditioner control unit performs air conditioner malfunction detection when it detects idle control malfunctions no less than three times in the engine control unit. For example, it detects whether an evaporator downstream temperature is within a ... | 03/10/1998 |
| 5717763 | Vocal mix circuit A vocal mix circuit shifts the phase of a mixed audio signal using a phase shifter, and achieves a mixed signal emphasizing the voice components thereof, by subtracting a signal which is not shifted from the signal shifted by the phase shifter. Gain throu... | 02/10/1998 |
| 5713217 | Refrigerant condenser with integral receiver A second header pipe forming a second header of a refrigerant condenser and a receiver are joined by brazing. In a portion where the second header pipe and receiver are communicated, four ribs provided at a perimeter of a communication hole of the second ... | 02/03/1998 |
| 5679655 | Method of treating lesions resulting from genital herpes with hyaluronic acid-urea pharmaceutical compositions This invention includes a pharmaceutical composition including a pharmaceutically acceptable carrier, urea, and hyaluronic acid or a pharmaceutically salt thereof. The invention also includes a method of treating disease of the cutis which includes applyi... | 10/21/1997 |
| 5674020 | Coating fluid holding member and oil coating roller using the same Disclosed is an oil coating roller composed of a coating fluid holding member comprising a porous hollow cylindrical molded body impregnated with a coating fluid, such as silicone oil, with a driving shaft inserted through the hollow portion thereof, both... | 10/07/1997 |
| 5660229 | Plate type heat transfer device A plate type heat transfer device which has a number of rectangular or oval cavities (or cell) in its transverse cross-section, is charged with a certain amount of a working fluid in each of the cavities (or cells). Heat from the lower surface of the plat... | 08/26/1997 |
| 5645117 | Tompkins turner A turner holds a wood blank while positioning it adjacent a cutting bit of a router to cut the blank into a shaped cylindrical object. The turner includes a mandrel and two mandrel wheels attachable to ends of the mandrel, which each have finger gripping ... | 07/08/1997 |
| 5631639 | Collision alarm system for automotive vehicle A collision alarm system for an automotive vehicle is provided which includes an object identifying circuit, a stationary object alarm circuit, a moving object alarm circuit, and an alarm inhibiting circuit. The object identifying circuit determines wheth... | 05/20/1997 |
| 5631242 | Hyaluronic acid-urea pharmaceutical compositions utilized for treatment of diseases of cutis This invention includes a pharmaceutical composition including a pharmaceutically acceptable carrier, urea, and hyaluronic acid or a pharmaceutically salt thereof. The invention also includes a method of treating disease of the cutis which includes applyi... | 05/20/1997 |
| 5592968 | Pressure supply device An apparatus and method for applying constant pressure to a plurality of pressure demanding mechanisms is disclosed. The apparatus includes a common rail, a plurality of pressure demanding mechanisms, a pressure supply source, and a plurality of branching... | 01/14/1997 |
| 5591287 | Process for producing layered ceramic product Process for producing a layered ceramic product which includes sintering layers of sinterable particulate ceramic material while in face-to-face contact. Before such contact, the surface of at least one of the layers is modified to provide a zone of weakn... | 01/07/1997 |
| 5591986 | Photoemitter electron tube and photodetector The present invention provides a photoemission device excellent in quantum efficiency of photoelectric conversion, a high-sensitive electron tube employing it, and a high-sensitive photodetecting apparatus. A photoemission device of the present invention ... | 01/07/1997 |
| 5591943 | Weight-sensing member for an electrical suspension weigher A weight-sensing member is made from material with good toughness and elastic deformability characteristics and has a top end, a bottom end and a broadened portion located between and integral with the first and second ends. The broadened portion has a pa... | 01/07/1997 |
| 5589930 | Optical radar apparatus The invention aims to increase an expansion angle in a road surface direction in a short-distance area without setting a detection range one-sidedly and without sacrificing a maximum detection distance. A double-focus lens is integrally formed by disposing a s... | 12/31/1996 |
| 5587593 | Light-emitting semiconductor device using group III nitrogen compound A light-emitting semiconductor device includes a sapphire substrate whose main surface orientation is tilted by 1 to 4 degrees from its axis "a" , and layers epitaxially formed thereon. Tilting the surface orientation of the sapphire substrate enabl... | 12/24/1996 |