Cozen O'Connor, P.C. - US Patent Attorneys and Agents

Attorney: Cozen O'Connor, P.C.

Number of patents: 34
Last date: February 12, 2008

Number	Title	Issue Date
7330525	Method and apparatus for maximizing radiation shielding during cask transfer procedures A transfer cask for maximizing the radiation shielding for spent nuclear fuel during cask transfer procedures has a cylindrical inner shell forming a cavity within which a spent nuclear fuel canister can be placed; a cylindrical outer shell concentric with and surro...	02/12/2008
7262050	Humanised antibodies CDR-grafted antibody heavy and light chains comprise acceptor framework and donor antigen binding regions, the heavy chains comprising donor residues at at least one of positions (6, 23) and/or (24, 48) and/or (49, 71) and/or (73, 75) and...	08/28/2007
7259278	Anti-S-phase tubulin ligands It is presently accepted that the mechanism of action for all anti-tumor tubulin ligands involves the perturbation of microtubule dynamics during the G2/M phase of cell division and subsequent entry into apoptosis (1). In this invention, we report a novel tubulin li...	08/21/2007
D547679	Watch	07/31/2007
7244615	Humanized antibodies CDR-grafted antibody heavy and light chains comprise acceptor framework and donor antigen binding regions, the heavy chains comprising donor residues at at least one of positions (6, 23) and/or (24, 48) and/or (49, 71) and/or (73, 75) and/or (76) and/or (78) and (88...	07/17/2007
7244587	Expression vectors encoding bacteriophage signal peptides Expression vectors encoding bacteriophage signal peptides are described. The vectors may be used for the heterologous expression and secretion of polypeptides such as antibodies in bacterial host cells. ...	07/17/2007
7241877	Humanised antibodies CDR-grafted antibody heavy and light chains comprise acceptor framework and donor antigen binding regions, the heavy chains comprising donor residues at at least one of positions (6, 23) and/or (24, 48) and/or (49, 71) and/or (73, 75) and/or (76) and/or (78) and (88...	07/10/2007
7227001	Manganese superoxide dimutase exon 3-deleted isoforms and nucleic acid molecules encoding the isoforms A new isoform of manganese superoxide dismutase (MnSOD) and polynucleotides encoding it have been identified. This isoform, MnSOD E3(−), is a splice variant lacking exon 3 of the full length MnSOD. The polypeptide can be expressed using appropriate host cells. Mod...	06/05/2007
7192688	Polybutadiene (meth)acrylate composition and method A composition comprising a polymer according to Structure 1 wherein R is H, Me, Et or C6H5; R′ is H or Me; R″ is H or Me; n=1 to 100; and Z=1 to 3, is disclosed. The composition can be c...	03/20/2007
7189714	N-type calcium channel antagonists for the treatment of pain Compounds useful for the treatment of pain in accord with the following structural diagram, wherein R1, R2 and R3 are any of a number of groups as defined in the specification and...	03/13/2007
7186733	4-(phenyl-(piperidin-4yl)-amino)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders Compounds of general formula I R1 is selected from any one of phenyl, pyridinyl, thienyl, furanyl, imidazolyl, pyrrolyl, triazolyl, thiazolyl, and pyridine N-oxide; where each ...	03/06/2007
7179646	Gene expression using T cell factor responsive element Disclosed are DNA elements and constructs useful for obtaining tumor-selective gene expression in tumors having a mutated β-catenin/APC pathway. In particular, the use of these constructs to express genes encoding therapeutic proteins in colorectal cancer cells is ...	02/20/2007
7175770	Methods and systems for groundwater remediation The present invention provides systems and methods for the remediation of contaminated water, soils and/or sediments. In some embodiments, the system includes one or more conduits for injection of hydrogen peroxide and ozone based reagents. ...	02/13/2007
7169810	Guanidine and amidine acid derivatives and analogs and methods of using the same The present invention releates to certain novel guanidine or amidine acid derivatives and analogs, to a process for preparing such compounds, having the utility in clinical conditions associated with insulin resistance, to methods for their therapeutic use and to ph...	01/30/2007
7156774	Reducing facial aging and appliance therefor A mass produced universal dental appliancee (1) comprises two parts, the parts intended in use to contact the posterior teeth on respective opposite sides of either the upper or lower jaw, each part comprising a composite structure comprising: ...	01/02/2007
7153865	N-type calcium channel antagonists for the treatment of pain Compounds useful for the treatment of pain in accord with the following structural diagram, wherein A, R1, b, R3, d, R4, R5, R6 and R7 are any of ...	12/26/2006
7151172	Attenuated DNA immunization cassettes for genetic vaccines The present invention is directed to nucleic acid molecules encoding attenuated, non-functional virion infectivity factor (vif) proteins. The nucleic acid molecules of the invention are inserted into recombinant expression vectors and administered to mammals in orde...	12/19/2006
7144914	3,7-diazabicyclo[3.3.0]octanes and their use in the treatment of cardiac arrhythmias There is provided compounds of formula (I) wherein R1 to R4, Ra to Rf, A and B have meanings given in the description, which are useful in the prophylaxis and in the treatment of arrhythmias, in particular atrial and ventr...	12/05/2006
7135333	Compositions that specifically bind to colorectal cancer cells and methods of using the same A unique transcription product, CRCA-1, and alternative translation products generated therefrom, are disclosed. The transcript and its translation products are markers for colorectal cells. Screening and diagnostic reagents, kits and methods for metastasized colore...	11/14/2006
7104931	Exercise system and method for simulating a swimming motion A system and method for simulating a swimming stroke wherein the resistance is supplied by resilient members connected to the user's arms and legs. In one aspect the invention is an exercise system comprising: a bench for supporting a user; means for securing to the...	09/12/2006
7097839	ST receptor binding compounds and methods of using the same Conjugated compounds which comprises an ST receptor binding moiety and a radiostable active moiety are disclosed. Pharmaceutical compositions comprising a pharmaceutically acceptable carrier or diluent, and a conjugated compound which comprises an ST receptor bindin...	08/29/2006
7067497	Modulation of telomere length by oligonucleotides having a G-core sequence Modified oligonucleotides having a GGG motif sequence and a sufficient number of flanking nucleotides to modulate the telomere length of a chromosome are provided. Methods of modulating telomere length of a mammalian chromosome in vitro and in vivo are also provided...	06/27/2006
7060834	N-type calcium channel antagonists for the treatment of pain Compounds useful for the treatment of pain in accord with the following structural diagram, wherein A, R1, b, R4, R5, R6, R7 and R8 are any of a n...	06/13/2006
7059170	Method and apparatus for measuring relative humidity of a mixture A method and apparatus for measuring relative humidity of a mixture that provides a quick response time for thermal lag while affording protection to fragile sensors. In one aspect, the invention is an apparatus comprising: a chamber having a membrane covering an op...	06/13/2006
7025093	Polyurethane elastomer gel insulating composition and use thereof The invention relates to the use of a thermally insulating composition in the form of crosslinked polyurethane elastomer gel, obtained by reacting at least one polyol and at least one polyisocyanate in the presence of at least one inert organic filler, for the therm...	04/11/2006
7005581	Electrical metallic tube, coupling, and connector apparatus and method A labor saving system, method, and apparatus for connecting or coupling lengths of electric metallic tubing (“EMT”). The invention uses couplings/connectors that have barbs that are designed to engage corresponding indentations on EMT to ensure proper installati...	02/28/2006
7005574	Electrical metallic tube, coupling, and connector apparatus and method A labor saving system, method, and apparatus for connecting or coupling lengths of electric metallic tubing (“EMT”). The invention uses couplings/connectors that have barbs that are designed to engage corresponding indentations on EMT to ensure proper installati...	02/28/2006
7001759	Compositions and methods for delivery of genetic material Methods of introducing genetic material into cells of an individual and compositions and kits for practicing the same are disclosed. The methods comprise the steps of contacting cells of an individual with a polynucleotide function enhancer and administering to the ...	02/21/2006
6995289	Process for synthesis of alpha, beta-unsaturated ketones A method for the synthesis of an α,β-unsaturated ketone useful for making substituted 1,4-dihydropyridines is described by reacting an aldehyde with pyrrolidine and then adding a ketone followed by trifluoroacetic acid at low temperature. The synthesis is used in ...	02/07/2006
6994299	Railroad crossing apparatus having improved rail connection and improved flangeway floor geometry and method incorporating the same An improved railroad frog, and method incorporating the same, for facilitating the intersection of rail lines in a more efficient, effective, and durable manner. In one aspect the invention is a railroad frog apparatus comprising: a body having flangeways that inter...	02/07/2006
6689606	Polynucleotide The present invention relates to a polynucleotide comprising a ubiquitous chromatin opening element (UCOE) which is not derived from an LCR. The present invention also relates to a vector comprising the polynucleotide sequence, a host cell comprising the ...	02/10/2004
6632927	Humanized antibodies CDR-grafted antibody heavy and light chains comprise acceptor framework and donor antigen binding regions, the heavy chains comprising donor residues at at least one of positions (6, 23) and/or (24, 48) and/or (49, 71) and/or (73, 75) and/or (76) and/or (...	10/14/2003
6608037	TCF responsive element Disclosed are DNA elements and constructs useful for obtaining tumour-selective gene expression in tumours having a mutated ଲ-catenin/APC pathway. In particular, the use of these constructs to express genes encoding therapeutic proteins in colorecta...	08/19/2003
6555339	Non-endogenous, constitutively activated human protein-coupled receptors Disclosed are constitutively activated, non-endogenous versions of endogenous human GPCRs comprising the following amino acid sequence region (C-terminus to N-terminus orientation) and/or the following nucleic acid sequence region (3' to 5' orientation) t...	04/29/2003

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Attorney: Cozen O'Connor, P.C.