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| Number | Title | Issue Date |
| 5563148 | Specific 5-HT3 antagonists This invention provides bicyclic carboxylic esters and amides, their pharmaceutical formulations, and a method for their use in treating migraine, emesis, gastrointestinal disorders, schizophrenia, or anxiety in mammals.... | 10/08/1996 |
| 5464826 | Method of treating tumors in mammals with 2',2'-difluoronucleosides A method of treating susceptible neoplasms in mammals comprising administering to a mammal in need of such treatment a pharmaceutically effective amount of a compound of the formula ##STR1## wherein: R1 is hydrogen; R2 is a base... | 11/07/1995 |
| 5442078 | Intermediates for specific 5-HT3 antagonists This invention provides bicyclic carboxylic esters and amides, their pharmaceutical formulations, and a method for their use in treating migraine, emesis, gastrointestinal disorders, schizophrenia, or anxiety in mammals.... | 08/15/1995 |
| 5430026 | 2'-deoxy-2',2'-difluoro (4-substituted pyrimidine) nucleosides, bicyclic derivatives,pharmaceutical compositions, and synthetic precursors The invention provides certain 2-Deoxy-2,2-Difluoro (4-Substituted) Pyrimidine Nucleosides that are effective as anti-cancer agents and in treating viral infections.... | 07/04/1995 |
| 5420266 | Process for anomerizing nucleosides A process for increasing the amount of a desired anomer nucleoside from an undesired anomeric nucleoside mixture thereof by contacting the mixture with a hydroxide base in an organic solvent.... | 05/30/1995 |
| 5401861 | Low temperature process for preparing alpha-anomer enriched 2-deoxy-2,2-difluoro-D-ribofuranosyl sulfonates A stereoselective process for preparing alpha-anomer enriched 2-deoxy-2,2-difluoro-D-ribofuranosyl sulfonates by contacting a lactol with an amine base in an inert solvent, adjusting the temperature and adding a sulfonating reagent.... | 03/28/1995 |
| 5364863 | Specific 5-HT3 antagonists This invention provides bicyclic carboxylic esters and amides, their pharmaceutical formulations, and a method for their use in treating migraine, emesis, gastrointestinal disorders, schizophrenia, or anxiety in mammals.... | 11/15/1994 |
| 4956388 | 3-aryloxy-3-substituted propanamines The present invention provides 3-aryloxy-3-substituted propanamines capable of inhibiting the uptake of serotonin and norepinephrine.... | 09/11/1990 |
| 4845128 | N([(4-trifluoromethylphenyl)amino]carbonyl)benzene sulfonamides This invention provides the use of certain benzenesulfonamide derivatives in the treatment of susceptible neoplasms in mammals. Also provided are certain novel benzenesulfonamide derivatives and their pharmaceutical formulations.... | 07/04/1989 |
| 4661505 | Leukotriene antagonists This invention provides novel alkane derivatives which are leukotriene antagonists, formulations of those derivatives, and a method of using those derivatives for the treatment of conditions characterized by an excessive release of leukotrienes.... | 04/28/1987 |
| 4647564 | Inotropic agents This invention provides certain pyridazinone derivatives, their pharmaceutical formulations, and their use as positive inotropic agents.... | 03/03/1987 |
| 4642379 | Intermediates for anticonvulsant agents This invention provides certain 4-acylamino benzamide derivatives, their pharmaceutical formulations, and their use as anticonvulsant agents.... | 02/10/1987 |
| 4636502 | Methods of producing a positive inotropic effect or vasodilation by administration of 2-phenyl imidazo pyrimidines and pyrazines This invention provides for certain phenyl-substituted imidazo compounds, their pharmaceutical formulations, and their use as positive inotropic agents and vasodilators.... | 01/13/1987 |
| 4631279 | 6-(pyridinylphenyl)dihydropyridazinones as inotropic agents This invention provides certain pyridazinone derivatives, their pharmaceutical formulations, and their use as positive inotropic agents.... | 12/23/1986 |
| 4629740 | Anticonvulsant agents This invention provides for certain benzamide derivatives and their pharmaceutical formulations and their use as anticonvulsant agents.... | 12/16/1986 |
| 4619935 | Stable oncolytic formulations Stable, sterile, ready-to-use formulations of oncolytic vincristine are provided.... | 10/28/1986 |
| 4617311 | Antiasthmatic method This invention provides a method of treating asthma in mammals which comprises administering an effective amount of Pinacidil.... | 10/14/1986 |
| 4617302 | Inotropic agents This invention provides certain pyridazinone derivatives, their pharmaceutical formulations, and their use as positive inotropic agents.... | 10/14/1986 |
| 4612330 | Antiinflammatory method This invention provides a method of treating inflammation and arthritis employing certain prostanoic acid derivatives. Pharmaceutical formulations employing these derivatives are also provided.... | 09/16/1986 |
| 4605661 | Aromastase inhibiting ,-diarylimidazole-4(5)-propionitriles, ,-diarylimidazole-4(5)-propionamides, and 4(5)-(2,2-diarylethyl)imidazoles This invention provides a method of inhibiting aromatase and treating or preventing estrogen-dependent diseases in mammals by administering certain imidazole derivatives. Pharmaceutical formulations of the imidazole derivatives and certain imidazoles are ... | 08/12/1986 |
