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Attorney: Conlin; David G., Corless; Peter F.


Number of patents: 149
Last date: March 19, 2002

1        
NumberTitleIssue Date
6358696Methods of treatment of eye trauma and disorders
Methods are provided for treatment of eye disorders and injury, including methods for treatment of reduced flow of blood or other nutrients to retinal tissue and/or optic nerve, methods for treatment of retinal ischemia and trauma and methods for treatmen...
03/19/2002
6304306Liquid crystal display device and method for producing the same
A liquid crystal display device includes substrates opposed to each other, a polymeric layer patterned into a predetermined pattern, and a liquid crystal layer at least partially surrounded by the polymeric layer. The polymeric layer and the liquid crysta...
10/16/2001
6298880Spool valve and manufacturing method therefor
The invention relates to a spool valve having an inner hybrid construction and a method of manufacturing the same, and the spool valve comprising sliding surface portions and grooves, the sliding surface portions and the grooves being arranged alternately...
10/09/2001
6287806Method for producing a biologically active recombinant cysteine-free peptide
A cysteine-free peptide is produced by producing a fused protein comprising a protein having cysteine at its N-terminal and a cysteine-free peptide ligated to the N-terminal and subsequently subjecting the fused protein to a reaction for cleaving the pept...
09/11/2001
6265081Integrally molded articles of polyamide resins
The present invention relates to an integrally molded article of polyamide resin comprising at least one primary molded pieces made of a primary molding material and at least one secondary molded pieces made of a secondary molding material, and having a w...
07/24/2001
6257709Image forming apparatus
An object of the invention is to provide an image forming apparatus which can form an image having high quality. The image forming apparatus of the invention at least comprises: a supply section having a toner carrier; a counter electrode disposed facing ...
07/10/2001
6197290Anion exchange resin-containing tablets
Disclosed are cholesterol-depressant, coated or non-coated tablets for oral administration, which comprise an anion exchange resin of formula (I): ##STR1## wherein X represents a physiologically-acceptable counter ion; and p represents an average degree o...
03/06/2001
6172998Semiconductor laser diode
The present invention relates to a semiconductor laser diode comprising a GaAs substrate and at least a first conduction-type clad layer, an active layer containing In, Ga and As as component elements, a second conduction-type first clad layer, a current ...
01/09/2001
6054747Integrated photoreceiver having metal-insulator-semiconductor switch
An integrated photoreceiver is provided. The photoreceiver includes a substrate, a metal-insulator-semiconductor switch (MISS) formed on a first portion of the substrate, and a photoreceiving structure formed on a second portion of the substrate for recei...
04/25/2000
6042926Glass substrate and thin film combination and method for producing the same
In a glass substrate and thin film combination, the glass substrate has a surface which is at least partially non-smooth, and the thin film is provided on the glass substrate in contact with the non-smooth part of the surface. Such a glass substrate and t...
03/28/2000
6022533Tablets containing anion exchange resin
The present invention relates to a pharmaceutical composition comprising anion exchange resin, silicon dioxide, crystalline cellulose, and pharmaceutically acceptable carriers and more particularly to tablets containing anion exchange resin prepared by mi...
02/08/2000
6017910PCP receptor ligands and the use thereof
The invention relates to 5-(iminomethano)-10,11-dihydro-5H-dibenzo[a,d]cycloheptene and derivatives thereof. The invention also relates to the use of such compounds for the treatment or prevention of neuronal loss in ischemia, hypoxia, brain or spina...
01/25/2000
6013675Therapeutic substituted guanidines
The present invention provides therapeutically useful substituted guanidines and methods of treatment and pharmaceutical compositions that utilize or comprise one or more of such guanidines....
01/11/2000
5989671Optical recording medium and manufacturing method thereof
An optical tape including an optical recording layer for permitting information to be optically recorded thereon and a light-reflective magnetic layer. The light-reflective magnetic layer which reflects light projected onto the recording layer, also permi...
11/23/1999
5986072Isolating substances with 3-[(5-(2,3-dimethoxy-6-methyl-1,4-benzoquinonyl)]-2-nonyl-2-propionic acid coupled to a microsphere
A substance possessing physiological activity is coupled to a styrene-glycidyl methacrylate polymer through a spacer, and is used to isolate from a mixture a substance that can adhere to the substance possessing physiological activity. Preferably the poly...
11/16/1999
5985935Treatment and prophylaxis of diseases caused by parasites, or bacteria
Aromatic compounds, or prodrugs thereof, which contain an alkylating site and which are capable of alkylating the thiol group in N-acetyl-L-cysteine, in particular bis-aromatic ଱,ଲ-unsaturated ketones, are used for the preparation of pharmaceu...
11/16/1999
5977027Pyrimidone isobutyric acid and herbicides containing the same
The present invention provides a nitrogen-containing cyclic compound represented by the formula (1): ##STR1## wherein R1 represents an alkyl group; R represents a hydrogen atom or an alkyl group; X represents an oxygen or sulfur atom or NR...
11/02/1999
5955507Therapeutic substituted guanidines
The present invention provides therapeutically useful substituted guanidines and methods of treatment and pharmaceutical compositions that utilize or comprise one or more of such guanidines....
09/21/1999
5951518Introducing device with flared sheath end
An improved percutaneous introducer device is provided that provides a splittable sheath having a flared lead in for the facile introduction of ancillary medical implements, such as small diameter catheters, guide wires and the like, and a hub member bein...
09/14/1999
5942231Method of treatment of atopic dermatitis with dried guava leaves
A method of treating a patient suffering from allergic diseases, comprises administering to said patient an effective amount of a pharmaceutical composition in dosage unit form comprising a dry powder of guava leaves....
08/24/1999
5942330Adhesive compositions and methods and articles of manufacture comprising same
The present invention provides novel curing adhesive film composition useful to produce structural materials, such as decorative panels for aircraft interiors, and methods and articles of manufacture that comprise such compositions. A preferred adhesive f...
08/24/1999
5924252Flooring sheet material
A sheet is provided which can be applied to a planar base and onto which floor boards or tiles can laid, wherein the sheet comprises adhesive strips on its lower and upper sides. The adhesive strips are suitably applied in the longitudinal direction of th...
07/20/1999
5922772Therapeutic substituted guanidines
The present invention provides therapeutically useful substituted guanidines and methods of treatment and pharmaceutical compositions that utilize or comprise one or more of such guanidines....
07/13/1999
5920767Method of forming a groove in a semiconductor laser diode and a semiconductor laser diode
The disclosure describes a method of forming a groove in a structure of a semiconductor laser diode, which comprises a crystal growth procedure of epitaxial growth of a core layer comprising MP, wherein M represents one or more of elements belonging to gr...
07/06/1999
5874247Protein disulfide isomerase and method of using
Protein disulfide isomerase, which catalyzes the exchange reaction between sulfhydryl and disulfide in a protein for formation of the most stable natural type disulfide bonds, is useful for formation of natural type disulfide bonds in a protein which is p...
02/23/1999
5852487LCD device having an input function and polymer substrates having dual function
A liquid crystal display apparatus having an input function includes a first substrate, a second substrate, and a third substrate; a display medium provided between the first substrate and the second substrate; a first electrode provided between the first...
12/22/1998
5851860Semiconductor device and method for producing the same
The semiconductor device of the invention includes: a substrate having an insulating surface; an active region formed on the insulating surface of the substrate, the active region being formed by a crystalline silicon film; and an insulating thin film for...
12/22/1998
5847006Therapeutic guanidines
The present invention provides N,N'-diaryl substituted guanidines having therapeutic utility. The compounds of the present invention are represented by the formula: ##STR1## wherein R and R1 represent hydrogen or other group and Ar and ...
12/08/1998
5837737Hydrazinedicarboximidamide compounds and pharmaceutical composition comprising same
Modulators of neurotransmitter release including substituted guanidines, N"-aminoguanidines, and N,N'N",N"'-tetrasubstituted hydrazinedicarboximidamides, and pharmaceutical compositions thereof are disclosed. Also disclosed are methods involving the use o...
11/17/1998
5834401Nitrogen-containing cyclic compounds and herbicides containing the same as active ingredient
The present invention provides a nitrogen-containing cyclic compound represented by the formula (1): ##STR1## (wherein R1 represents an alkyl group; R represents a hydrogen atom or an alkyl group; X represents an oxygen or sulfur atom or N...
11/10/1998
5821190Catalyst comprising iridium, alkaline metal, alkaline earth or rare earth metal, and metal carbide or metal nitride
The present invention provides a catalyst and method for purifying exhaust gases, having superior performance of NOx purification to exhaust gases containing oxygen and nitrogen oxides, particularly superior performance of NOx elimination to exhaust gases...
10/13/1998
5811412Reducing tetracycline resistance in living cells
The present invention provides an improved methodology by which therapeutically to overcome resistance to tetracycline in living cells including bacteria, parasites, fungi, and rickettsiae. The methodology employs a blocking agent such as C5 ester derivat...
09/22/1998
5808708Lighting apparatus
A lighting apparatus for irradiating a liquid crystal display panel from the back includes a light guiding plate having at least an end which is bent in a direction opposite to the liquid crystal display panel, and a light source disposed on the back surf...
09/15/1998
5805243Liquid crystal projector using a spatial light modulator and two rotating color filters
A liquid crystal display apparatus which includes: a light-addressed liquid crystal light valve including a photoconductive layer and a liquid crystal layer between a pair of light transmitting substrates, each of the light transmitting substrates having ...
09/08/1998
5804435Method for obtaining organic solvent-resistant microorganisms and organic solvent-resistant microorganisms obtainable by the method
The present invention provides a method for obtaining organic solvent resistant microorganisms which comprises subjecting a microbial parent strain to mutagenesis and then to selective cultivation in the presence of 0.1% to 10% by volume (v/v) of concentr...
09/08/1998
5801147Polypeptides and use thereof
Disclosed are (1) a polypeptide represented by formula (I), or a pharmaceutically acceptable amide, ester or salt thereof: His-Ser-Asp-Gly-Ile-Phe-Thr-Asp-Ser-Tyr-Ser-Arg-Tyr-Arg-Lys-Gln-NH-CHX-CO-A la-Val-Lys-Lys-Tyr-Y SEQ ID NO:13 (I)...
09/01/1998
5798390Tri- and tetra-substituted guanidines and their use as excitatory amino acid antagonists
Tri- and tetra-substituted guanidines which exhibit a high binding affinity to phencyclidine (PCP) receptors and, more preferably, low affinity to the brain sigma receptors. These guanidine derivatives act as non-competitive inhibitors of glutamate induce...
08/25/1998
5782807Releasably locking introducer devices
A releasably locking dilator/sheath medical introducer device is provided having a dilator with a non-circular cross-sectional shape to enable insertion of a catheter, guide wire and the like into a patient. More particularly, the invention provides an in...
07/21/1998
5784137Liquid crystal display device and method for producing the same
A liquid crystal display device includes substrates opposed to each other, a polymeric layer patterned into a predetermined pattern, and a liquid crystal layer at least partially surrounded by the polymeric layer. The polymeric layer and the liquid crysta...
07/21/1998
5767162Tri-and tetra-substituted guanidines and their use as excitatory amino acid antagonists
Tri- and tetra-substituted guanidines which exhibit a high binding affinity to phencyclidine (PCP) receptors and, more preferably, low affinity to the brain sigma receptors. These guanidine derivatives act as non-competitive inhibitors of glutamate induce...
06/16/1998
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