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| Number | Title | Issue Date |
| 7323553 | Non-affinity purification of proteins The present invention relates to a method for protein purification that involves the combination of non-affinity chromatography with HPTFF. ... | 01/29/2008 |
| 7319006 | Serpentine transmembrane antigens expressed in human cancers and uses thereof Described is a novel family of cell surface serpentine transmembrane antigens. Two of the proteins in this family are exclusively or predominantly expressed in the prostate, as well as in prostate cancer, and thus members of this family have been termed “STEAP” ... | 01/15/2008 |
| 7285649 | Isolated nucleic acids, vectors and host cells encoding ErbB3 antibodies Antibodies are disclosed which bind to ErbB3 protein and further possess any one or more of the following properties: an ability to reduce heregulin-induced formation of an ErbB2-ErbB3 protein complex in a cell which expresses ErbB2 and ErbB3; the ability to increas... | 10/23/2007 |
| 7166714 | Serpentine transmembrane antigens expressed in human cancers and uses thereof Described is a novel family of cell surface serpentine transmembrane antigens. Two of the proteins in this family are exclusively or predominantly expressed in the prostate, as well as in prostate cancer, and thus members of this family have been termed “STEAP” ... | 01/23/2007 |
| 7153426 | Charged filtration membranes and uses therefor The invention relates to charged filtration membranes and their use for separation of a protein from solvent, low molecular weight solutes or a mixture of proteins. Modification of the membranes to generate charge includes modification of membrane pores to alter cha... | 12/26/2006 |
| 7053186 | Antibodies immunospecific for STEAP1 Described is a novel family of cell surface serpentine transmembrane antigens. Two of the proteins in this family are exclusively or predominantly expressed in the prostate, as well as in prostate cancer, and thus members of this family have been termed “STRAP” ... | 05/30/2006 |
| 7038017 | Antibody purification A process for purifying an antibody is provided. In this process, a mixture containing the antibody and a contaminant is subjected to low pH hydrophobic interaction chromatography (LPHIC) at low salt concentration. The antibody is eluted from the column in the fract... | 05/02/2006 |
| 7001550 | Charged filtration membranes and uses therefor The invention relates to charged filtration membranes and their use for separation of a protein from solvent, low molecular weight solutes or a mixture of proteins. Modification of the membranes to generate charge includes modification of membrane pores to alter cha... | 02/21/2006 |
| 6926833 | Tangential-flow filtration system The present invention includes a system and method for transferring a selected solute species from a fluid mixture to a fluid media. The system of the present invention includes a convergent channel for passing a fluid mixture containing a selected species tangentia... | 08/09/2005 |
| 6653287 | Use of leukemia inhibitory factor and endothelin antagonists A leukemia inhibitory factor antagonist, alone or in combination with an endothelin antagonist, may be used for treatment of heart failure. The antagonist(s) are administered in a chronic fashion, in therapeutically effective amounts, to achieve this purp... | 11/25/2003 |
| 6582928 | Carbohydrate-directed cross-linking reagents The invention provides heterobifunctional cross-linking reagents and methods of using the cross-linking reagents. The cross-linking reagents of the invention combine a nucleophilic hydrazide residue with an electrophilic maleimide residue allowing couplin... | 06/24/2003 |
| 6387270 | Tangential-flow filtration system The present invention includes a system and method for transferring a selected solute species from a fluid mixture to a fluid media. The system of the present invention includes a convergent channel for passing a fluid mixture containing a selected specie... | 05/14/2002 |
| 6252051 | ErbB4 receptor-specific neuregulin related ligand antibodies and uses therefor The invention concerns a novel neuregulin related ligand (NRG3) including fragments and variants thereof, as new members of the neuregulin family of compounds. The invention also concerns methods and means for producing NRG3. The native polypeptides of th... | 06/26/2001 |
| 6221249 | Tangential-flow filtration system The present invention includes a system and method for transferring a selected solute species from a fluid mixture of a fluid media. The system of the present invention includes a convergent channel for passing a fluid mixture containing a selected specie... | 04/24/2001 |
| 6124435 | Carbohydrate-directed cross-linking reagents The invention provides heterobifunctional cross-linking reagents and methods of using the cross-linking reagents. The cross-linking reagents of the invention combine a nucleophilic hydrazide residue with an electrophilic maleimide residue, allowing coupli... | 09/26/2000 |
| 6117650 | Assay for cardiac hypertrophy An assay to test for hypertrophic activity in myocytes is described where wells are precoated with D-MEM/F-12 and fetal calf serum, plated with myocytes, cultured, and any change in size of the cells is determined. The growth medium may contain insulin, t... | 09/12/2000 |
| 6077940 | Free solution ligand interaction molecular separation method The present invention is directed to novel methods for enhancing the ability to separate a species of interest from other different species present in a free solution mixture thereof which takes advantage of interactions that occur between soluble, small ... | 06/20/2000 |
| 6054051 | Tangential-flow filtration system The present invention includes a system and method for transferring a selected solute species from a fluid mixture to a fluid media. The system of the present invention includes a convergent channel for passing a fluid mixture containing a selected specie... | 04/25/2000 |
| 6027650 | Adsorption chromatography The present invention relates to methods useful for purifying materials using adsorbent chromatography, preferably in an expanded bed or packed bed configuration without the need to use a moving packed bed adapter, thereby improving elution characteristic... | 02/22/2000 |
