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| Number | Title | Issue Date |
| 8097652 | AMPA receptor potentiators The present invention relates to a compound of Formula (I) or a pharmaceutically acceptable salt thereof which is useful for the treatment of conditions associated with glutamate hypofunction, such as psychiatric and neurological disorders. | 01/17/2012 |
| 7652064 | AMPA receptor potentiators The present invention relates to AMPA receptor potentiators of Formula I: formulations comprising them, methods for their use, and intermediates useful for their preparation. ... | 01/26/2010 |
| 7642361 | Thiophene and furan compounds The present invention relates to thiophene and furan compounds and their pharmaceutically acceptable salts, and further relates to their use in treating schizophrenia, cognitive deficits associated with schizophrenia, Alzheimer's disease, dementia of the Alzheimer's... | 01/05/2010 |
| 7625932 | Pyrrole and pyrazole derivatives as potentiators of glutamate receptors The present invention relates to pyrrole and pyrazole compounds of formula (I) and their pharmaceutically acceptable salts, and further relates to their use in treating schizophrenia, cognitive deficits associated with schizophrenia, Alzheimer's disease, dementia of... | 12/01/2009 |
| 7619096 | 3-Aminopyrrolidines as inhibitors of monoamine uptake The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof, which are useful for the inhibition of the uptake of one or more physiologically active monoamines (serotonin, norepinep... | 11/17/2009 |
| 7615648 | Aminomethyl-azacycle derivatives as inhibitors of monoamine uptake The present invention provides compounds of formula (I) wherein A is (1), (2), (3), (4), (5), (6) or (7) and wherein R1, R7, y and Ar1 are defined herein. The compounds are inhibitors of the uptake of one or more monoamines selected from serotonin, norepi... | 11/10/2009 |
| 7595315 | Morpholine derivatives as norepinephrine reuptake inhibitors Compounds of the general formula (I) are inhibitors of the reuptake of norepinephrine. As such, they may be useful for the treatment of disorders of the central and/or peripheral nervous system. ... | 09/29/2009 |
| 7538232 | Process for the asymmetric synthesis of duloxetine This invention provides an improved asymmetric process for the synthesis of duloxetine involving arylation of Compounds of Formula I. ... | 05/26/2009 |
| 7432280 | 3-aminopiperidines and 3-aminoquinuclidines as inhibitors of monoamine uptake The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof, which are useful for the inhibition of the uptake of one or more physiologically active monoamines (serotonin, norepinep... | 10/07/2008 |
| 7393868 | AMPA receptor potentiators The present invention relates to AMPA receptor potentiators of Formula I: formulations comprising them, methods for their use, and intermediates useful for their preparation. ... | 07/01/2008 |
| 7384941 | 2-(phenoxymethyl)-and 2-(phenylthiomethyl)-morpholine derivatives for use as selective norepinephrine reuptake inhibitors Compounds of formula (I): wherein A is S or O; R is H; Ar is an optionally substituted phenyl group; X is an optionally substituted phenyl group, a C1-C4 alkyl, a C3... | 06/10/2008 |
| 7354920 | Aryl and heteroaryl morpholine derivatives Compounds of formula (I) wherein Rx is H; Ry is H or C1-C4 alkyl; each Rz is independently H or C1-C4 alkyl; X represents O; Y represents OH or OR; R is C... | 04/08/2008 |
| 7335660 | Isochroman compounds for treatment of CNS disorders This invention relates to compounds of formula (I) where R1 to R12, —W—V—, —X—Y—, p and n have the values defined in claim 1, their preparation and use as pharmaceuticals for the tre... | 02/26/2008 |
| 7230011 | Benzenesulfonic acid indol-5-yl esters as antagonists of the 5ht receptor The present invention relates to compounds of formula I: which are antagonists of 5-HT6 receptor. ... | 06/12/2007 |
| 7157488 | N-(2-Arylethyl) benzylamines as antagonists of the 5-HTreceptor The present invention provides compounds of formula I pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are antagonists of the 5-HT6 receptor. The present invent... | 01/02/2007 |
