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| Number | Title | Issue Date |
| 7499634 | Ophthalmic camera, ophthalmic camera adaptor and methods for determining a haemoglobin and glucose level of a patient Provided is an ophthalmic camera comprising: a camera having a camera lens; at least one illumination means; and an ophthalmic lens. The centres of the ophthalmic lens and camera lens are aligned to form an alignment axis. The at least one illumination means is capa... | 03/03/2009 |
| 7491779 | Polyvinyl ethers The present invention relates to polyvinyl ethers and to their use as supports for synthetic methods (organic synthesis, peptide synthesis, oligonucleotide synthesis, oligosaccharide synthesis or any other synthetic procedure) and to their use for chromatographic ap... | 02/17/2009 |
| 7455990 | Method of extracting recombinant hexose oxidase A method is described for releasing a soluble or membrane associated intracellular protein of interest (POI) comprising the steps of: providing a cell comprising a soluble or membrane associated intracellular POI; contacting the cell with a membrane extracting compo... | 11/25/2008 |
| 7449495 | Retinoid derivatives with antiangiogenic, antitumoral and proapoptotic activities Described and claimed are compounds of Formula (I) in which R, R′, R″, A, and D have the meanings described in the text, as useful agents in the cure of pathologies characterized by altered angiogenesis and as antitumorals. ... | 11/11/2008 |
| 7410773 | Method of preparing an undifferentiated cell A method of increasing the relative number of cells expressing one or more stem cell markers in a cell population including committed cells is described. The method comprises: i. contacting the cell population with an agent that operably engages said committed cells... | 08/12/2008 |
| 7390795 | Treatment and prevention of tissue damage A method for the treatment or prevention of tissue damage in a subject having an inflammatory and/or tissue damaging condition, which comprises administering to the subject an effective amount of a compound capable of inhibiting the binding of C-reactive protein (CR... | 06/24/2008 |
| 7371552 | Polypeptide We disclose a food additive comprising a PS4 variant polypeptide, in which the PS4 variant polypeptide is derivable from a parent polypeptide having non-maltogenic exoamylase activity, in which the PS4 variant polypeptide comprises substitutions at the following pos... | 05/13/2008 |
| 7371423 | Method for preparing flour doughs and products made from such doughs using lipase Method of improving the rheological properties of a flour dough and the quality of bread, alimentary paste products, noodles and cakes wherein glycerol oxidase or a combination of glycerol oxidase and a lipase is added to the dough and dough improving compositions c... | 05/13/2008 |
| 7371402 | Use of a composition There is provided use of a pectin composition to prepare an aqueous composition having high yield stress characteristics without substantial gelation, wherein the pectin composition comprises at least a population of pectin that is calcium sensitive; wherein the pec... | 05/13/2008 |
| 7371820 | Nutraceuticals for the treatment, protection and restoration of connective tissues The invention relates to a method for isolating from connective tissue a variety of glycosaminoglycan (GAG)-polypeptide complexes and polypeptides which are substantially free of contaminating DNA and other molecules such as viruses which may be associated with the ... | 05/13/2008 |
| 7361677 | Polycyclic sulphamate compounds suitable for use as inhibitors of aromatase and/or sulphatase There is provided a compound of Formula I wherein each T is independently selected from H, hydrocarbyl, —F—R, and a bond with one of D, E, P or Q, or together with one of P and Q forms a ring; Z is a suitable atom the v... | 04/22/2008 |
| 7355004 | Protein lipase inhibitor for flour and dough The present invention relates to the isolation of and characterization of a novel lipase inhibitor and its effect on different lipases. The present invention also relates to the use of a lipase inhibitor as a screen for lipases. The present invention also relates to... | 04/08/2008 |
| 7342004 | Thioether sulphamate steroids as steroid inhibitors and anti-cancer compounds There is provided use of a compound of Formula XI: wherein R3 is a sulphamate group and at least of R1 or R2 is a thioether group as disclosed by the present specification, capable of inhibi... | 03/11/2008 |
| 7341851 | IL-8 like protein This present invention relates to a novel protein, termed INSP085, herein identified as an IL-8 like protein and to the use of this protein and nucleic acid sequence from the encoding genes in the diagnosis, prevention and treatment of disease. ... | 03/11/2008 |
| 7335650 | Composition There is provided a pharmaceutical composition comprising (i) a compound of the formula wherein: X is a hydrocarbyl ring having at least 4 atoms in the ring; K is a hydrocarbyl group; Rs is a sulphamate group; (ii) optional... | 02/26/2008 |
| 7326417 | IGF-1 as feline vaccine adjuvant, in particular against feline retroviruses The invention relates to feline IGF-1, to the nucleotide sequence encoding this protein and to the use of IGF-1 as adjuvant for the vaccination of cats, in particular against the feline retroviruses FIV and FeLV. IGF-1 may be used in the form of protein or may be ex... | 02/05/2008 |
| 7276513 | Steroidal compounds for inhibiting steroid sulphatase There is provided a compound of formula XII, wherein G is H or a substituent, and wherein R1 is a sulphamate group. ... | 10/02/2007 |
| 7268219 | Method for producing or enhancing a T-cell response against a target cell using a complex comprising an HLA class I molecule and an attaching means A complex comprising an HLA Class 1 molecule and attaching means for selectively attaching the HLA class 1 molecule to a target cell is disclosed, and a method is provided for producing or enhancing an immunological response against a target cell, by attaching said ... | 09/11/2007 |
| 7264965 | Method for producing or enhancing a T-cell response against a target cell using a complex comprising an HLA class I molecule and an attaching means A complex including an HLA class I molecule and attaching means for selectively attaching the HLA class I molecule to a target is disclosed, and a method is provided for producing or enhancing an immunological response against a target cell, by attaching said comple... | 09/04/2007 |
| 7211246 | Compositions comprising oestrone-3-0-sulphamate and trail (TNF-related apoptosis inducing ligand) The present invention provides a composition comprising (i) a compound comprising a sulphamate group (“a sulphamate compound”); and (ii) an apoptosis inducer. ... | 05/01/2007 |
| 7211648 | Topical compositions for the treatment, protection and restoration of skin and connective tissues The invention relates to uses of GAG-peptide complexes and polypeptides obtained from connective tissue albeit indirectly which are substantially free of DNA for the treatment, protection and restoration of skin and connective tissues. The invention provides a topic... | 05/01/2007 |
| 7202272 | Compound A compound is described. In particular, a non-steroidal sulphamate compound is described. The compound is suitable for use as an inhibitor of oestrone sulphatase. The compound is of general Formula (A), wherein R... | 04/10/2007 |
| 7129269 | Compound The instant invention relates to sulphamate compounds of formula I, wherein A represents a ring structure, B represents a ring structure, D a ring structure, C is a bond, E is a link joining ring structure B to the ring structure D, X represents a suitable first gro... | 10/31/2006 |
| 7129231 | Regulation of intracellular glucocorticoid concentrations This invention relates to the interconversion of inactive 11-keto steroids with their active 11B-hydroxy equivalents, to methods by which the conversion of the inactive to the active form may be controlled, and to useful therapeutic effects which may be obtained as ... | 10/31/2006 |
| 7122532 | Regulation of intracellular glucocorticoid concentrations This invention relates to the interconversion of inactive 11-keto steroids with their active 11B-hydroxy equivalents, to methods by which the conversion of the inactive to the active form may be controlled, and to useful therapeutic effects which may be obtained as ... | 10/17/2006 |
| 7122531 | Regulation of intracellular glucocorticoid concentrations This invention relates to the interconversion of inactive 11-keto steroids with their active 11B-hydroxy equivalents, to methods by which the conversion of the inactive to the active form may be controlled, and to useful therapeutic effects which may be obtained as ... | 10/17/2006 |
| 7119081 | Oestrogen-17-sulphamates as inhibitors of steroid sulphatase There is provided a compound of Formula I wherein X is a ring system; R1 is any one of a sulphamate group, a phosphonate group, a thiophosphonate group, a sulphonate group or a sulphonamide group; R | 10/10/2006 |
| 7115760 | Process for controlling the fatty acid chain composition of triglycerides and use thereof The present invention relates to a process for controlling the fatty acid chain composition of triglycerides wherein a feed stream comprises a mixture of triglycerides containing at least one long chain. Said mixture is substantially free of trishort chain triglycer... | 10/03/2006 |
| 7098218 | Steroidal compounds for inhibiting steroid sulphatase There is provided a compound having Formula (I) wherein G is H or a substituent, and wherein R1 is any one of a sulphamate group, a phosphonate group, a thiophosphonate group, a sulphonate group or a sulphonamide group, capable of inhibiting steroid sulph... | 08/29/2006 |
| 7098199 | Steroid sulphatase inhibitors A method of inhibiting steroid sulphatase activity in a subject in need of same is described. The method comprises administering to said subject a steroid sulphatase inhibiting amount of a ring system compound; which ring system compound comprises a ring to w... | 08/29/2006 |
| 7087400 | Regulation of intracellular glucocorticoid concentrations This invention relates to the interconversion of inactive 11-keto steroids with their active 11B-hydroxy equivalents, to methods by which the conversion of the inactive to the active form may be controlled, and to useful therapeutic effects which may be obtained as ... | 08/08/2006 |
| 7078395 | Methods for treating or preventing cancer by preventing, inhibiting or arresting cell cycling There is provided use of a cyclic compound or a pharmaceutically active salt thereof in the manufacture of a medicament to prevent and/or inhibit and/or arrest cell cycling, wherein the cyclic compound comprises at least one ring, ... | 07/18/2006 |
| 7067503 | 17-aryl linker derivatised estrogen 3-sulphamates as inhibitors of steroid sulphatase There is provided a compound comprising a steroidal ring system and a group R1 selected from any one of a sulphamate group, a phosphonate group, a thiophosphonate group, a sulphonate group or a sulphonamide group; wherein the D ring of the steroidal ring ... | 06/27/2006 |
| 7037510 | Hybrids of M. tuberculosis antigens The present invention discloses fusion proteins of the immunodominant antigens ESAT-6 and Ag85B from Mycobacterium tuberculosis or homologues thereof, and a tuberculosis vaccine based on the fusion proteins, which vaccine induces efficient immunological memor... | 05/02/2006 |
| 6951649 | Methods of making neuraminidase-supplemented compositions The present invention relates to a method for formulating a vaccine composition which comprises an anti-influenza vaccine, wherein the improvement of the vaccine composition is that the vaccine includes, as an additive, neuraminidase (NA). The base anti-influenza va... | 10/04/2005 |
| 6800333 | Method of depositing in situ a solid film on a substrate In preferred aspects the present invention provides: (i) a method of and apparatus for depositing material, preferably a film, on a substrate, the method comprising the steps of: providing a substrate; heating the substrate; generating an aerosol comprising droplets... | 10/05/2004 |
