Collier; Kenneth J. - US Patent Attorneys and Agents

Attorney: Collier; Kenneth J.

Number of patents: 39
Last date: September 27, 2011

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Number	Title	Issue Date
8027791	Self-improving classification system A self-improving classification system classifies specimens based on class identifiers. The system stores specimen profiles in a database that is updated with additional specimen profiles and with follow-up data that corrects classification of specimens that were in...	09/27/2011
7902352	Isolated nucleic acid duplex for reducing huntington gene expression Disclosed herein are sequences, molecules and methods used to suppress the expression of HD genes encoding for huntingtin protein in primates including Macaca mulatta and Homo sapiens. These sequences, molecules and methods aid in the study of the path...	03/08/2011
7829694	Treatment of neurodegenerative disease through intracranial delivery of siRNA The present invention provides devices, small interfering RNA, and methods for treating a neurodegenerative disorder comprising the steps of surgically implanting a catheter so that a discharge portion of the catheter lies adjacent to a predetermined infusion site i...	11/09/2010
7819842	Chronically implantable guide tube for repeated intermittent delivery of materials or fluids to targeted tissue sites A therapy delivery system for the intermittent delivery of biologics, chemicals, or pharmaceuticals into tissues involves a chronically implantable guide tube having a guide cannula with a proximal and a distal end, an access port mounted on the proximal end of the ...	10/26/2010
7741375	Polyketal polymers, and methods of making and using same Polyketal polymers, and methods of making and using such polyketal polymers are disclosed herein. The polyketal poylmers can be useful for applications including, for example, medical devices and pharmaceutical compositions. In a preferred embodiment, the polyketal ...	06/22/2010
7732591	Compositions, devices and methods for treatment of huntington's disease through intracranial delivery of sirna The present invention provides devices, small interfering RNAs, and methods for treating a neurodegenerative disorder comprising the steps of surgically implanting a catheter so that a discharge portion of the catheter lies adjacent to a predetermined infusion site ...	06/08/2010
7731653	System and method for genetically treating cardiac conduction disturbances The present invention provides delivery systems for and methods of delivering conduction protein genetic material to cardiac cells in localized areas of the heart to improve the conductance therein. More specifically, there is provided a system and method for delive...	06/08/2010
7658727	Implantable medical device with enhanced biocompatibility and biostability An implantable medical device comprising a drug-loaded polymer overlaid with a fabric that promotes tissue ingrowth is useful in a wide variety of tissue engineering applications. The invention includes, for example, prosthetic heart valves, annuloplasty rings, and ...	02/09/2010
7632306	Foam-type vascular prosthesis with well-defined angio-permissive open porosity A vascular prosthesis is constructed from a well-defined pore structure to allow uninterrupted ingrowth of connective tissue into a wall of the prosthesis. Several different methods can be used to produce the prosthesis, including a vacuum impregnation technique, a ...	12/15/2009
7538163	Modification of thermoplastic polymers A method of preparing a polymer involving reacting at least one backbone carbamate (and/or optional urea) nitrogen of a thermoplastic polymer with a modification agent to form a modified polymer. ...	05/26/2009
7349740	Myocardial stimulation In general, the invention is directed to methods for electrically stimulating transplanted biological material, such as transplanted cells, to improve the performance of the heart during systole. In particular, the invention is directed to devices and techniques for...	03/25/2008
7310545	Method and device to form a sensor using isolated cardiomyocytes A method and device are described to form a sensor using a cardiomyocyte by advancing a catheter into the tissue of interest, cardiac in the preferred embodiment, and using the catheter to ablate a cone- or a dome-shaped region to form an electrically isolated secti...	12/18/2007
7122356	Method for attachment of biomolecules to medical device surfaces A method for making a medical device having at least one biomolecule immobilized on a substrate surface is provided. One method of the present invention includes immobilizing a biomolecule comprising an unsubstituted amide moiety on a biomaterial surface. Another me...	10/17/2006
7122027	Implantable medical device with controllable gaseous agent release system The present invention generally relates to medical devices. Specifically, the invention pertains to implantable medical devices that produces gaseous agents from precursors and releases them into the body. More specifically, the invention provides for the controlled...	10/17/2006
7033388	Porous synthetic vascular grafts with oriented ingrowth channels A vascular prosthesis is constructed from a structure having interconnected, helically oriented channel-porosity to allow oriented ingrowth of connective tissue into a wall of the prosthesis. The prosthesis can have a small internal diameter of 6 mm or less. Several...	04/25/2006
7031775	Method and system for myocardial infarction repair An implantable system is provided that includes: a cell repopulation source comprising genetic material, undifferentiated and/or differentiated contractile cells, or a combination thereof capable of forming new contractile tissue in and/or near an infarct zone of a ...	04/18/2006
6879861	Polymeric materials with improved dielectric breakdown strength A novel polymeric electrically insulating material that includes a linked voltage stabilizing agent. Also provided are methods of making the novel material and articles and devices that incorporate the novel material, particularly implantable medical devices. ...	04/12/2005
6824561	Implantable system with drug-eluting cells for on-demand local drug delivery An implantable system that includes a carrier and eukaryotic cells, which produce and release a therapeutic agent, and a stimulating element for stimulating the release of the therapeutic agent. The system can also include a sensing element for monitoring a physiolo...	11/30/2004
6775574	Method and system for myocardial infarction repair An implantable system is provided that includes: a cell repopulation source comprising genetic material, undifferentiated contractile cells, or a combination thereof capable of forming new contractile tissue in and/or near an infarct zone of a patient's myocardium; ...	08/10/2004
6673108	Transmural concentric multilayer ingrowth matrix within well-defined porosity A multilayer ingrowth matrix is constructed within well-defined porosity of a prosthetic material. The matrix consists of either proteinaceous or synthetic layers or gradients, or a combination of proteinaceous and synthetic layers or gradients. Each laye...	01/06/2004
5661167	Prolyl endopeptidase inhibitors The present invention relates to compounds of formula 1, ##STR1## including all of its stereoisomers, compositions, and processes for preparation of the same. The compounds of the present invention are also useful in their pharmacological activities ...	08/26/1997
5623052	Synthetic peptide lung surfactants having covalently bonded antioxidants Synthetic pulmonary surfactants having antioxidant properties consisting of a complex of a polypeptide of 3-4 amino acid residues, with an antioxidant moiety, and a lipid consisting of one or more of the lipids associated with natural pulmonary surfactant...	04/22/1997
5500429	Calcium uptake inhibitors This invention relates to 1-aryl-3-pyridinyl-2-propene-1-ones, the use of these compounds as calcium uptake inhibitors in leukocytes and thrombocytes, and pharmaceutical compositions containing these compounds as active ingredients, and the process of the...	03/19/1996
5447911	Ghilanten antimetastatic principle from the south american leech, Haementeria ghilianii A method for the inhibition of tumor metastases is described herein. The method makes use of the administration of an antimetastatic factor isolated from the leech Haementeria ghilianii....	09/05/1995
5446068	1-phenyl-3-phenyl-2-propyne-1-ones as calcium uptake inhibitors This invention relates to 1-phenyl-3-phenyl-2-propyne-1-ones, the use of these compounds as calcium uptake inhibitors in leukocytes and thrombocytes, and pharmaceutical compositions containing these compounds as active ingredients, and the process of thei...	08/29/1995
5428019	Bombesin analogs Agonists and Antagonist of bombesin are derivatives of naturally occurring bombesin possessing a methyl sulfide or a methyl amide bond connecting the two amino acids on the carboxy terminal end. Agonist and antagonist activities are confirmed using conven...	06/27/1995
5428018	Phenylalanine analogs of bombesin Disclosed are Agonists and Antagonists of bombesin which are derivatives of naturally occurring bombesin possessing modified derivatives of phenylalanine. Agonist and antagonist activities are confirmed using conventional competitive binding and biochemic...	06/27/1995
5409942	Calcium uptake inhibitors This invention relates to 1-phenyl-3-aryl-2-propyne-1-ones, the use of these compounds as calcium uptake inhibitors in leukocytes and thrombocytes, and pharmaceutical compositions containing these compounds as active ingredients, and the process of their ...	04/25/1995
5407954	Arylalkoxyphenoxy-imidazoline compounds The present invention is directed to a new class of arylalkoxyphenoxy-imidazoline compounds and their use for the treatment of depression, anxiety, hypertension, and migraine headaches....	04/18/1995
5395823	Neuropeptide Y agonists and partial agonists Agonists of NPY which are derivatives of naturally occurring NPY. The agonism is confirmed using conventional competitive binding and biochemical assays and the use of these derivatives in a variety of conditions in which neuropeptide Y is implicated is a...	03/07/1995
5385911	Anti-herpes castanospermine esters Certain Castanospermine ester derivatives of the formula: ##STR1## wherein R, R1 and R2 are each independently hydrogen, C1-14 alkanoyl, C1-14 alkenoyl, cyclohexanecarbonyl, C1-8 alkoxyacetyl, ...	01/31/1995
5384119	Method of preventing neutrophil mediated connective tissue damage Oligomers of the formula ##STR1## have demonstrated effectiveness in preventing connective tissue damage....	01/24/1995
5248825	Calcium uptake inhibitors This invention relates to 1-phenyl-3-phenyl-2-propyne-1-ones, the use of these compounds as calcium uptake inhibitors in leukocytes and thrombocytes, and pharmaceutical compositions containing these compounds as active ingredients, and the process of thei...	09/28/1993
5236898	Cyclic anticoagulant peptides This invention relates to cyclic peptide derivatives which are useful anticoagulant agents....	08/17/1993
5232912	Anticoagulant peptides This invention relates to peptide derivatives which are useful anticoagulant agents....	08/03/1993
5223518	1-phenyl-3-aryl-2-propyne-1-one useful as calcium uptake inhibitors This invention relates to 1-phenyl-3-aryl-2-propyne-1-ones, the use of these compounds as calcium uptake inhibitors in leukocytes and thrombocytes, and pharmaceutical compositions containing these compounds as active ingredients, and the process of their ...	06/29/1993
5216008	Arylalkoxyphenoxy-imidazoline compounds The present invention is directed to a new class of arylalkoxyphenoxy-imidazoline compounds and their use for the treatment of depression, anxiety, hypertension, and migraine headaches....	06/01/1993
5192747	Anticoagulant peptides The invention relates to peptide derivatives which are useful anticoagulant agents....	03/09/1993
5192745	Cyclic anticoagulant peptides This invention relates to cyclic peptide derivatives which are useful anticoagulant agents....	03/09/1993

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Attorney: Collier; Kenneth J.