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| Number | Title | Issue Date |
| 5185169 | Deodorant porous polymer and a deodorant fibrous material using the same A deodorant porous polymer having excellent deodorant effects is provided. The deodorant porous polymer is in the shape of substantially uniform particulates or an aggregate thereof, and is obtained by the hydrolysis and polycondensation of at least one a... | 02/09/1993 |
| 5071351 | Dental implant system The dental implant system of the present invention has a decreased surface contact angle and includes a biocompatible titanium implant which has been treated by the plasma cleaning and sterilization process of the present invention. An implant that has ex... | 12/10/1991 |
| 4853332 | Structural genes, plasmids and transformed cells for producing cysteine depleted muteins of biologically active proteins Muteins of biologically active proteins such as IFN-ଲ and IL-2 in which cysteine residues that are not essential to biological activity have been deleted or replaced with other amino acids to eliminate sites for intermolecular crosslinking or incorr... | 08/01/1989 |
| 4830962 | Recombinant diphtheria toxin fragments Recombinant vectors which are effective in expressing DNA sequences encoding specific fragments of diphtheria toxins at high levels in recombinant host cells are disclosed. Both a fragment consisting of the enzymatically active A chain of diphtheria toxin... | 05/16/1989 |
| 4789702 | Feline leukemia virus vaccine Polypeptides that are synthesized or expressed directly in microorganisms, include an amino acid sequence that is homologous to at least a portion of gp70 envelope protein of FELV, and are immunogens that elicit or prime a humoral response in cats and imm... | 12/06/1988 |
| 4753894 | Monoclonal anti-human breast cancer antibodies Murine monoclonal antibodies are prepared and characterized which bind selectively to human breast cancer cells, are IgGs or IgMs, and when conjugated to ricin A chain, exhibit a TCID 50% against at least one of MCF-7, CAMA-1, SKBR-3, or BT-20 cells of le... | 06/28/1988 |
| 4623627 | Monoclonal antibody having specificity for the double-stranded conformation of native DNA and diagnostic methods using same Monoclonal antibodies having conformation-dependent specificity for native dsDNA, as exemplified by the IgM antibody produced by murine hybridoma ATCC No HB 8329. These antibodies are used to detect DNA duplex formation in DNA hybridization tests.... | 11/18/1986 |
| 4588585 | Human recombinant cysteine depleted interferon-ଲ muteins Muteins of biologically active proteins such as IFN-ଲ and IL-2 in which cysteine residues that are not essential to biological activity have been deleted or replaced with other amino acids to eliminate sites for intermolecular crosslinking or incorr... | 05/13/1986 |
| 4582788 | HLA typing method and cDNA probes used therein HLA typing based on restriction length polymorphism is carried out by: digesting an individual's HLA DNA with a restriction endonuclease that produces a polymorphic digestion pattern with HLA DNA; subjecting the digest to genomic blotting using a labeled ... | 04/15/1986 |
| 4569908 | Multiclass hybrid interferons New multiclass hybrid interferon polypeptides, their corresponding encoding recombinant DNA molecules and transformed hosts which produce the new interferons are described. The amino acid sequences of these hybrids include at least two different subsequen... | 02/11/1986 |
| 4569915 | P. obtusus strain A P. obtusus strain AU124 having the identifying characteristics of NRRL No. 15595, the strain produces high levels of pyranose-2-oxidase.... | 02/11/1986 |
| 4569910 | Methods and reagents for pyranosone production Methods for producing substantially pure pyranosone from pyranose, especially glucosone from glucose. A pyranose-2-oxidase enzyme which is free of substantially all glucosone-utilizing enzyme contaminants which are measurably active at a selected pH betwe... | 02/11/1986 |
| 4569913 | P. obtusus pyranose-2-oxidase preparation A substantially pure pyranose-2-oxidase preparation obtained from P. obtusus, and preferably from a high-producer strain thereof. The preparation is substantially free of glucosone-utilizing enzyme contaminants having measurable activity at a pH between a... | 02/11/1986 |
| 4568645 | Fungal pyranose-2-oxidase preparations A substantially pure pyranose-2-oxidase preparation obtained from C. versicolor or L. betulinus. The preparation is substantially free of glucosone-utilizing enzyme contaminants having measurable activity at a pH between about 4.4 and 7.0.... | 02/04/1986 |
| 4567144 | Method of producing long chain wax esters from ethanol A process for producing wax esters having the general structural formula RCO2 R', where R and R' are radicals selected from the group consisting of CH3 (CH2)a CH.dbd.CH(CH2)b - and CH3... | 01/28/1986 |
| 4555957 | Bi-directional liquid sample handling system An automatic liquid transfer system includes a horizontally translatable table and a pipette that is translatable both vertically and horizontally in a direction transverse to the axis of translation of the table. The table accommodates one or more titer ... | 12/03/1985 |
| 4554839 | Multiple trough vessel for automated liquid handling apparatus Apparatus for accurately transferring liquids for filling or diluting microliter quantities of regents, analytes or cells for bioassays and the like include a vessel having a plurality of troughs for supplying an array of pipettes to effect the transfer. ... | 11/26/1985 |
| 4518584 | Human recombinant interleukin-2 muteins Muteins of biologically active proteins such as IFN-ଲ and IL-2 in which cysteine residues that are not essential to biological activity have been deleted or replaced with other amino acids to eliminate sites for intermolecular crosslinking or incorr... | 05/21/1985 |
| 4499188 | Bacterial production of heterologous polypeptides under the control of a repressible promoter-operator A process for bacterially producing heterologous polypeptides, particularly those such as human IFN-ଲ that inhibit bacterial growth, in which bacteria that have been transformed to express the heterologous polypeptide under the control of a trp prom... | 02/12/1985 |
| 4478094 | Liquid sample handling system An automatic liquid transfer system includes a horizontally translatable table and a vertically translatable set of pipettes. The table accommodates a titer tray having a multiplicity of receptacles to be filled, or holding liquid samples to be diluted, a... | 10/23/1984 |
| 4450103 | Process for recovering human IFN-ଲ from a transformed microorganism A process for recovering IFN-ଲ from transformed bacteria comprising: disrupting the cell membranes of the bacteria; solubilizing the IFN-ଲ from the disruptate into an aqueous medium with a solubilizing agent such as sodium dodecyl sulfate; ext... | 05/22/1984 |
| 4369181 | Process for treating proliferative skin diseases using certain 6,8-substituted ribofuranosylpurine-3',5'-cyclic phosphates Proliferative skin diseases such as psoriasis are treated by topically administering cAMP analogs of the following formula to the afflicted skin site at a dose that preferentially and significantly activates type II protein kinase: ##STR1## wher... | 01/18/1983 |
| 4339237 | Free amine-containing polymeric dyes Soluble polymeric colorants composed of free amine groups and chromophoric groups covalently bonded to an organic backbone are disclosed. The number of free amine groups is not less than one-half the number of chromophoric groups. The colorants are charac... | 07/13/1982 |
| 4316918 | Products including edibles colored with polymeric red colors Polymeric red colors having the structure ##STR1## wherein R1 and R2 are independently selected from among hydrogen, halos, lower alkyls, lower alkoxies, nitros, and sulfonates, R3 is selected from hydrogens, alkyls a... | 02/23/1982 |
| 4298595 | Pharmaceutical preparations containing a polymeric agent for releasing 5-aminosalicylic acid or its salts into the gastrointestinal tract An intestinal anti-inflammatory preparation comprising a polymeric agent for releasing 5-aminosalicylic acid or its salts is disclosed. The polymeric agent comprises a nonabsorbable pharmacologically acceptable organic polymer backbone containing aromatic... | 11/03/1981 |
| 4282201 | Pharmaceutical comprising drug and polymer This invention concerns polymers of the general formula: ##STR1## wherein R is a multivalent hydrocarbon radical and Het is a 5 to 8 membered heterocyclic system having a nitrogen, oxygen or sulfur hetero atom. The polymers are useful for making arti... | 08/04/1981 |
| 4271041 | High surface area molybdenum oxycarbide catalysts Novel, high specific surface area molybdenum oxycarbide catalysts are disclosed. They are prepared by the vapor condensation of molybdenum hexacarbonyl and catalyze the reaction of hydrogen and carbon monoxide to form hydrocarbons. Carburization of the mo... | 06/02/1981 |
| 4271113 | Process for forming a passageway in an osmotic device A process is disclosed for forming an outlet passageway in an osmotic dispensing device. The process comprises compressing a drug formulation into a solid mass, forming a recess in the solid mass, and then spray coating the mass with a wall forming materi... | 06/02/1981 |
| 4265874 | Method of delivering drug with aid of effervescent activity generated in environment of use A method is disclosed for delivering a drug substantially free of rapid precipitation from an osmotic device. The osmotic device comprises a semipermeable wall surrounding a compartment, housing (1) a drug that exhibits limited solubility under neutral an... | 05/05/1981 |
| 4259102 | Composition comprising useful agent such as fertilizers, housed in heterocyclic polymer This invention concerns polymers of the general formula: ##STR1## wherein R is a multivalent hydrocarbon radical and Het is a 5 to 8 membered heterocyclic system having a nitrogen, oxygen or sulfur hetero atom. The polymers are useful for making arti... | 03/31/1981 |
| 4256108 | Microporous-semipermeable laminated osmotic system An osmotic therapeutic system for delivering a drug is disclosed. The system comprises a drug delivery module which module comprises a rate controlling laminated wall surrounding a reservoir and has a portal for delivering drug from the system. The lamina... | 03/17/1981 |
| 4250611 | Process for making drug delivery device with reservoir An intravaginal contraceptive system for the pre-programmed, unattended delivery of an antifertility steroid is disclosed. The system comprises (a) an antifertility steroid, (b) a delivery module comprising a reservoir for storing the steroid in an amount... | 02/17/1981 |
| 4250790 | Capo An adjustable, positive locking capo for use with stringed instruments such as banjos and guitars is disclosed. The capo comprises a frame (19) having a top arm (25) that bears against the strings when the capo is in operation and a side arm (26) that ext... | 02/17/1981 |
| 4249531 | Bioerodible system for delivering drug manufactured from poly(carboxylic acid) A device for the controlled continuous administration of an active agent to an environment of use is disclosed. The device comprises a body of erodible agent release rate controlling material containing an agent dispersed therethrough; the rate controllin... | 02/10/1981 |
| 4247292 | Natural tissue heart valve fixation process A process for fixing a natural tissue heart valve whereby the valve has improved hydraulic performance is disclosed. The valve is first placed in glutaraldehyde with the valve cusps kept in the closed position by applying hydraulic pressure to the ventric... | 01/27/1981 |
| 4246397 | Polymers comprising heterocyclic system This invention concerns polymers of the general formula: ##STR1## wherein R is a multivalent hydrocarbon radical and Het is a 5 to 8 membered heterocyclic system having a nitrogen, oxygen or sulfur hetero atom. The polymers are useful for making arti... | 01/20/1981 |
| 4241733 | Patient-care apparatus with device for dispensing anti-pathogenic agent A patient-care apparatus housing a device for controlling the presence of pathogens is disclosed. The apparatus comprises a container with an inlet port and a device in the apparatus for controlling the presence of pathogens.... | 12/30/1980 |
| 4237893 | Cervical dilator A self-powered cervical dilator is disclosed. The dilator comprises (1) an expandable housing positioned around (2) a swellable laminate, which laminate surrounds (3) a support member. The laminate comprises (a) a lamina formed of an absorbent material la... | 12/09/1980 |
| 4237885 | Delivery system with mated members for storing and releasing a plurality of beneficial agents A delivery system is disclosed. The system is useful for the preprogrammed, unattended delivery of at least one beneficial agent to a pre-selected environment of use. The system comprises (I), a beneficial agent (II), a delivery module comprising, (a) a c... | 12/09/1980 |
| 4236517 | Patient-care apparatus with chemoprophylactic system A patient-care apparatus housing a device for controlling the presence of pathogens is disclosed. The apparatus comprises a container with an inlet port and a device in the apparatus for controlling the presence of pathogens.... | 12/02/1980 |
