Did You Know...
...that Thomas Edison's patent application on his phonograph was approved by the Patent Office in just seven weeks? In contrast, it took Gordon Gould, the inventor of the laser, 30 years to obtain his patent -- finally awarded in 1988!
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| Number | Title | Issue Date |
| 7932257 | Substituted pyrazolo[4,3-d]pyrimidines as aurora kinase inhibitors The present invention provides compounds having the formula: wherein A-B together represent one of the following structures: ... | 04/26/2011 |
| 7915274 | Nitrogen containing heterocyclic compounds and medicines containing the same Compounds represented by the following general formula: [wherein X1, X2, X3 and X4 each independently represent a single bond, C1-6 alkylene, etc.; A2 repres... | 03/29/2011 |
| 7910623 | Synthesis of scabronines and analogues thereof A novel synthesis of scabronines, which are related to a broader class of angularly fused tricyclic diterpenoids known as cyathanes, is provided. Scabronine G, its methyl ester derivative, and other analogs have been shown to have neurotrophic activity. Therefore, t... | 03/22/2011 |
| 7910335 | Methods and compositions for labeling nucleic acids The present invention relates to methods for the labeling of nucleic acid polymers in vitro and in vivo. In particular, the methods include a [3+2] cycloaddition between a nucleotide analogue incorporated into a nucleic acid polymer and a reagent attached to a label... | 03/22/2011 |
| 7893277 | Poly(ethylene glycol) containing chemically disparate endgroups The present invention provides bifunctional polymers, methods of preparing the same, and intermediates thereto. These compounds are useful in a variety of applications including the PEGylation of biologically active molecules. The invention also provides methods of ... | 02/22/2011 |
| 7847235 | Laser obstacle ranging and display A novel laser obstacle warning and ranging system, for detecting hard-to-see long and thin obstacles in particular, comprises a fiber laser including a signal diode, a circulator, an erbium doped fiber, a wavelength division multiplexer, a narrow band reflector, a f... | 12/07/2010 |
| RE41990 | Synthesis of epothilones, intermediates thereto, analogues and uses thereof The present invention provides convergent processes for preparing epothilone A and B, desoxyepothilones A and B, and analogues thereof. Also provided are analogues related to epothilone A and B and intermediates useful for preparing same. The present invention furth... | 12/07/2010 |
| 7879861 | Combi-molecules having EGFR and DNA targeting properties A series of new chemical agents that demonstrate anti-tumor activity are described. The new chemical agents combine two major mechanisms of anti-tumor action. In an embodiment, the agents are capable of both inhibiting EGFR and damaging DNA while also, upon degradat... | 02/01/2011 |
| 7879335 | Glycoconjugates, glycoamino acids, intermediates thereto, and uses thereof The present invention provides novel n-alkenyl glycosides and glycoconjugates, n-alkyl glycoamino acids, and methods for the synthesis thereof. In another aspect, the present invention provides novel clustered glycopeptides and methods for the synthesis thereof. In ... | 02/01/2011 |
| 7875638 | Synthesis of epothilones, intermediates thereto, analogues and uses thereof The present invention provides compounds of formula (I): as described generally and in classes and subclasses herein. The present invention additionally provides pharmaceutical compositions comprisi... | 01/25/2011 |
| 7858576 | Method for targeting lysosomal enzymes Targeted therapeutics that localize to a specific subcellular compartment such as the lysosome are provided. The targeted therapeutics include a therapeutic agent and a targeting moiety that binds a receptor on an exterior surface of the cell, permitting proper subc... | 12/28/2010 |
| 7854935 | Herbal therapy for the treatment of asthma The present invention provides herbal formulas, and compositions thereof, that can treat or reduce the severity, intensity, or duration of asthma and asthma-related symptoms. The compositions may optionally include one or more adjuvants, cytokines, encapsulating mat... | 12/21/2010 |
| 7854934 | Glycoconjugates, glycoamino acids, intermediates thereto, and uses thereof The present invention provides novel glycosides and glycoconjugates, glycoamino acids, and methods for the synthesis thereof. In another aspect, the present invention provides novel clustered glycopeptides and methods for the synthesis thereof. In still another aspe... | 12/21/2010 |
| 7853947 | System for virtualizing access to named system objects using rule action associated with request A method for virtualizing access to named system objects includes the step of receiving a request to access a system object from a process executing in the context of a user isolation scope, the request including a virtual name for the system object. A rule associat... | 12/14/2010 |
| 7853679 | Systems and methods for configuring handling of undefined policy events Systems and methods for configuring and evaluating policies that direct processing of one or more data streams are described. A configuration interface is described for allowing users to specify object oriented policies. These object oriented policies may allow any ... | 12/14/2010 |
| 7853678 | Systems and methods for configuring flow control of policy expressions Systems and methods for configuring and evaluating policies that direct processing of one or more data streams are described. A configuration interface is described for allowing users to specify object oriented policies. These object oriented policies may allow any ... | 12/14/2010 |
| 7838619 | Biodegradable polyketal polymers and methods for their formation and use The present invention relates to biodegradable biocompatible polyketals, methods for their preparation, and methods for treating animals by administration of biodegradable biocompatible polyketals. In one aspect, a method for forming the biodegradable biocompatible ... | 11/23/2010 |
| 7831728 | Methods and systems for real-time seeking during real-time playback of a presentation layer protocol data stream A method for real-time seeking during real-time playback of presentation layer protocol data streams includes the step of receiving, by a foreground protocol engine, a request for rendering the contents of a packet in a presentation layer protocol data stream compri... | 11/09/2010 |
| 7825113 | 2-oxy-benzoxazinone derivatives for the treatment of obesity The use of a compound comprising formula (I): or a salt, ester, amide or prodrug thereof in the inhibition of an enzyme whose preferred mode of action is to catalyse the hydrolysis of an ester functionality, e.g. in the con... | 11/02/2010 |
| 7824687 | Clustered multi-antigenic carbohydrate constructs, methods for their preparation, and uses thereof The present invention provides novel clustered multi-antigenic constructs having the structure: and methods for the synthesis thereof. In still another aspect, the present invention provides methods... | 11/02/2010 |
| 7820175 | Herbal therapy for the treatment of food allergy The present invention provides herbal formulas, and compositions thereof, that can treat or reduce the severity, intensity, or duration of food allergy and food allergy related symptoms. The compositions may optionally include one or more adjuvants, cytokines, encap... | 10/26/2010 |
| 7816544 | Synthesis of rocaglamide natural products via photochemical generation of oxidopyrylium species The present invention provides new strategies for the synthesis of compounds of the rocaglamide family and related natural products. In particular, the new biomimetic synthetic approach involves photochemical generation of an oxidopyrylium species from a 3-hydroxych... | 10/19/2010 |
| 7816518 | Porphyrin derivatives and their use in photon activation therapy The present invention relates to the use of a compound of formula (I) in the manufacture of a pharmaceuticals composition for cell death by photo activation therapy and the use of the compounds in the prevention and/or treatment of cancer. | 10/19/2010 |
| 7814287 | Using writeable page tables for memory address translation in a hypervisor environment A method and system for using writeable page tables to increase performance of memory address translation in computing environments utilizing a hypervisor. Guest operating systems are given temporary write-access to a page table page after the system confirms that s... | 10/12/2010 |
| 7812054 | Lipoxin analogs and methods for the treatment of periodontal disease This invention provides new lipoxin analogs, compositions containing analogs, and methods of using these compounds and compositions for treating and preventing oral inflammation, including gingivitis, periodontitis, and other forms of periodontal disease. The invent... | 10/12/2010 |
| 7793220 | Scalable derivative services An efficient method for parsing HTML pages identifies pages containing a mix of static and dynamic content. The pages are parsed to form abstract syntax trees (ASTs), which are then cached along with the pages. When a later version of a page is retrieved, it is comp... | 09/07/2010 |
| 7792934 | Loading of server-stored user profile data One or more computer-implemented methods provided by computer-readable media for providing and loading user profile data from a server computer system to a client computer system may be used together with the server and client computer systems. The client computer s... | 09/07/2010 |
| 7790150 | Dual phase drug release system The present invention relates to conjugate comprising a carrier substituted with one or more occurrences of a moiety having the structure (I): wherein each occurrence of M is independently a modifier having a molecular weight ≦10 kDa; denotes direct of indirect at... | 09/07/2010 |
| 7781427 | Process for preparing quinoline compounds and products obtained therefrom Methods for synthesizing tetrahydroquinoline-containing compounds are provided, along with synthetic intermediates and products associated with such methods. ... | 08/24/2010 |
| D622139 | Hot food container | 08/24/2010 |
| 7779034 | Method and system for accessing a remote file in a directory structure associated with an application program executing locally A method and system for accessing a file in a directory structure associated with an application includes a method of accessing a file in a directory structure associated with an application. A request by an application for access to a file is intercepted. The reque... | 08/17/2010 |
| 7776853 | 2-amino-benzoxazinone derivatives for the treatment of obesity The use of a compound comprising formula (I): or a salt, ester, amide or prodrug thereof in the inhibition of an enzyme whose preferred mode of action is to catalyse the hydrolysis of an ester functionality, e.g. in the con... | 08/17/2010 |
| 7767687 | Pyrido pyrimidinones, dihydro pyrimido pyrimidinones and pteridinones useful as RAF kinase inhibitors The present invention provides compounds having the formula: wherein A-B together represent one of the following structures: ... | 08/03/2010 |
| 7767421 | Methods and compositions for labeling nucleic acids The present invention relates to methods for the labeling of nucleic acid polymers in vitro and in vivo. Certain methods are provided that include a [3+2] cycloaddition between a nucleotide analogue incorporated into a nucleic acid polymer and a reagent attached to ... | 08/03/2010 |
| 7766511 | LED light fixture A light fixture using LEDs includes a lower skin layer possessing heat transfer properties. A circuit board is affixed to the lower skin layer, and a single LED, or a plurality of LEDs, is electrically connected to the circuit board. The single LED, or plurality of ... | 08/03/2010 |
| 7763446 | Chimeric DNA-binding proteins Chimeric proteins containing composite DNA-binding regions are disclosed together with DNA constructs encoding them, compositions containing them and applications in which they are useful. ... | 07/27/2010 |
| 7763441 | Modulators of gluconeogenesis The present invention provides methods of affecting gluconeogenesis by altering the levels or activity of DUSP4 and/or EGR1. Pharmaceutical compositions comprising or encoding modulators of gluconeogenesis are also disclosed. ... | 07/27/2010 |
| 7750164 | Synthesis of epothilones, intermediates thereto, analogues and uses thereof The present invention provides convergent processes for preparing epothilone A and B, desoxyepothilones A and B, and analogues thereof. Also provided are analogues related to epothilone A and B and intermediates useful for preparing same. The present invention furth... | 07/06/2010 |
| 7734777 | Systems and methods for monitoring components of a remote access server farm The present application is related methods to monitor a state of one or more components of a remote access server farm by an intermediary to distinguish between operating and functional components and improve farm availability for user application requests. The inte... | 06/08/2010 |
| D617369 | Braille writer | 06/08/2010 |
