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| Number | Title | Issue Date |
| 8173361 | Method of determining metabolism of a test agent A method for detecting one or more metabolites of a test agent in a tissue including: A) incubating a test agent and an enzyme within a three-dimensional structure comprising a first mold or polymer scaffold, a semi-permeable membrane, and a second mold or polymer s... | 05/08/2012 |
| 8160751 | Devices, systems and methods for flow-compensating pump-injector synchronization Systems, devices, and methods to mitigate the pressure disturbance associated with the injection of low-pressure analyte samples into a high-pressure HPLC fluid stream, to enhance chromatographic performance related to retention time and reproducibility. The preferr... | 04/17/2012 |
| 8147562 | Three dimensional construct for the design and fabrication of physiological fluidic networks The present invention relates to methods for the design and fabrication of biological constructs, such as organ simulants or organ replacements, which contain complex microfluidic architecture. Designs of the present invention provide increased space in the lateral ... | 04/03/2012 |
| 8139211 | Fluorescence polarization imaging device and method The present invention is directed to a novel multi-spectral exogenous fluorescence polarization imaging technique that enables rapid imaging of large tissue fields. The imaging device includes a tunable monochromatic light source and a CCD camera. Linear polarizers ... | 03/20/2012 |
| 8107067 | Opaque additive to block stray light in teflon AF light-guiding flowcells The present invention is directed to the use of a light absorbing wall material to eliminate stray light paths in light-guiding structures, such as those used for HPLC absorbance detection. More specifically, the present invention relates to the use of carbon-doped ... | 01/31/2012 |
| 8097456 | Nanotopographic compositions and methods for cellular organization in tissue engineered structures The present invention relates to tissue engineered compositions and methods comprising nanotopographic surface topography (“nanotopography”) for use in modulating the organization and/or function of multiple cell types. ... | 01/17/2012 |
| 8045263 | Device and method for wide-field and high resolution imaging of tissue A device for wide-field and high resolution imaging of an object surface includes first and second imaging modalities, a lens associated with the second imaging modality. The first imaging modality is high resolution with a first observation line. The second imaging... | 10/25/2011 |
| 7960166 | Microfabricated compositions and processes for engineering tissues containing multiple cell types The present invention relates to a three-dimensional system, and compositions obtained therefrom, wherein individual layers of the system comprise channels divided longitudinally into two compartments by a centrally positioned membrane, and wherein each compartment ... | 06/14/2011 |
| 7917250 | Devices, systems and methods for flow-compensating pump-injector synchronization Systems, devices, and methods to mitigate the pressure disturbance associated with the injection of low-pressure analyte samples into a high-pressure HPLC fluid stream to enhance chromatographic performance related to retention time and reproducibility. The injectio... | 03/29/2011 |
| 7820980 | High speed combination multi-mode ionization source for mass spectrometers The present invention combines ionization modes produced by, for example, electrospray (ESI), atmospheric pressure chemical ionization (APCI), and thermospray for analysis of molecules. Specifically, this invention relates to the creation of a new source apparatus c... | 10/26/2010 |
| 7776021 | Micromachined bilayer unit for filtration of small molecules Methods and materials for making an apparatus which duplicates the functionality of a physiological system id provided. ... | 08/17/2010 |
| 7670797 | Method of determining toxicity with three dimensional structures A method of determining toxicity of a test agent in a tissue including A) incubating a test agent within a three-dimensional tissue engineered structure comprising a first mold or polymer scaffold, a semi-permeable membrane, and a second mold or polymer scaffold, wh... | 03/02/2010 |
| 7627363 | Polarized light imaging devices and methods The present invention is directed to a novel multi-spectral contrast agent-enhanced polarized light imaging technique that enables rapid imaging of large tissue fields. The imaging device includes a tunable monochromatic light source and a CCD camera. Linear polariz... | 12/01/2009 |
| 7564550 | Fluorescence polarization imaging devices and methods The present invention is directed to a novel multi-spectral exogenous fluorescence polarization imaging technique that enables rapid imaging of large tissue fields. The imaging device includes a tunable monochromatic light source and a CCD camera. Linear polarizers ... | 07/21/2009 |
| 6988504 | Umbrella assembly An umbrella assembly comprising a base, a pole mounted on the base extending upwardly and outwardly from the base, a carriage slidably mounted on the pole, and an umbrella frame including an adapter releasably engagable with the carriage. A handle is rotatably mount... | 01/24/2006 |
| 7371400 | Multilayer device for tissue engineering The invention provides for translating two-dimensional microfabrication technology into the third dimension. Two-dimensional templates are fabricated using high-resolution molding processes. These templates are then bonded to form three-dimensional scaffold structur... | 05/13/2008 |
| 7289205 | Fluorescence polarization imaging devices and methods The present invention is directed to a novel multi-spectral exogenous fluorescence polarization imaging technique that enables rapid imaging of large tissue fields. The imaging device includes a tunable monochromatic light source and a CCD camera. Linear polarizers ... | 10/30/2007 |
| 7157270 | Lightweight chamber having variable configurations and a method for making such An anabolic chamber constructed of a plastic with additives to create desirable characteristics such as resistance to corrosion and bacteria growth. The anabolic chamber has a double-wall structure with internal support ribs for creating a water jacket for facilitat... | 01/02/2007 |
| 7065763 | Method of reducing contention of a highly contended lock protecting multiple data items Featured is a method or process for reducing contention of a highly contended software lock(s) that is protecting multiple data items, where the software has a plurality of code paths accessing the data items. The method includes creating additional partition locks ... | 06/20/2006 |
| 6996969 | Multi-mode shutdown system for a fuel metering unit A multi-mode shutdown system in combination with a fuel metering unit of an engine to prevent normal fuel delivery during engine malfunction such as the engine overspeeding. The multi-mode shutdown system includes a shutdown solenoid capable of closing a pressurizin... | 02/14/2006 |
| 6994099 | Shelter with twist tight canopy and method for assembling same A shelter having an internal frame comprised of a roof supported by legs. A canopy covers the roof of the frame to provide protection from the elements. The canopy is taughtly held onto the frame by cords which pass through sleeves in the front and back of the canop... | 02/07/2006 |
| 6962485 | Constant bypass flow controller for a variable displacement pump A fuel metering unit for controlling a variable displacement pump including a main metering valve in fluid communication with the pump for metering an output of the pump, a pressure regulator in fluid communication with the metering valve to create a spill return an... | 11/08/2005 |
| 6652395 | Collapsible sports goal assembly A collapsible sports goal assembly movable between an open position and a closed position has a base frame, a front frame, and a top frame, and one or more connecting leg assemblies to provide support for the goal assembly. The base frame, the front frame... | 11/25/2003 |
| 6623250 | Fuel metering unit A fuel metering unit including a pump having a rotor with a plurality of slots. The pump also includes a pivotally movable cam ring coaxially arranged with respect to the rotor. Vanes are slideably disposed in the slots for maintaining contact with the ca... | 09/23/2003 |
