Quotables
"We live in a society exquisitely dependent on science and technology, in which hardly anyone knows anything about science and technology."
Carl Sagan
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 8183305 | Radiopaque infiltrant The invention provides an infiltrant for dental application that comprises crosslinking monomers, having a penetration coefficient PC>50 cm/s. In accordance with the invention the infiltrant comprises at least one nanoscale radiopaque filler and/or radiopaque organi... | 05/22/2012 |
| 8182991 | FEN-1 endonucleases, mixtures and cleavage methods The present invention relates to means for the detection and characterization of nucleic acid sequences, as well as variations in nucleic acid sequences. The present invention also relates to improved cleavage means for the detection and characterization of nucleic ... | 05/22/2012 |
| D660182 | Battery dispenser | 05/22/2012 |
| 8178506 | Oligomeric compounds and compositions for use in modulation of small non-coding RNAs Compounds, compositions and methods are provided for modulating the expression and function of small non-coding RNAs. The compositions comprise oligomeric compounds, targeted to small non-coding RNAs. Methods of using these compounds for modulation of small non-codi... | 05/15/2012 |
| 8168675 | Compositions and methods for treating neurodegenerative diseases The present invention relates to compositions and methods for treating neurodegenerative diseases. In some embodiments, the present invention provides compositions for treating and preventing presbycusis. ... | 05/01/2012 |
| 8168405 | Covalent tethering of functional groups to proteins and substrates therefor A mutant hydrolase optionally fused to a protein of interest is provided. The mutant hydrolase is capable of forming a bond with a substrate for the corresponding nonmutant (wild-type) hydrolase which is more stable than the bond formed between the wild-type hydrola... | 05/01/2012 |
| 8153592 | Modulating toll-like receptor activity This description provides methods and materials related to modulating Toll-like receptor activity. For example, methods and materials for increasing or decreasing the responsiveness of a TLR4 polypeptide are provided. ... | 04/10/2012 |
| 8148147 | Compositions and methods for treating and diagnosing pancreatic cancer The present invention relates to the field of oncology and provides novel compositions and methods for diagnosing and treating pancreatic cancer. In particular, the present invention provides pancreatic cancer stem cells useful for the study, diagnosis, and treatmen... | 04/03/2012 |
| 8143232 | Gene fusion targeted therapy The present invention relates to compositions and methods for cancer therapy, including but not limited to, targeted inhibition of cancer markers. In particular, the present invention relates to recurrent gene fusions as clinical targets for prostate cancer. ... | 03/27/2012 |
| 8138909 | Portable detection system and method A method and apparatus for providing assay information to a portable detection unit, by way of a remote server in communication with the portable detection unit or a consumable with stored information for use with the portable detection unit. Global Positioning Syst... | 03/20/2012 |
| 8137911 | Preparation and use of single-stranded transcription substrates for synthesis of transcription products corresponding to target sequences The present invention provides methods, compositions and kits for using an RNA polymerase for making transcription products corresponding to a target sequence by obtaining single-stranded DNA transcription substrates that comprise a single-stranded promoter that is ... | 03/20/2012 |
| 8136668 | Box for retail display of breakable items The present invention relates to articles of manufacture for the packaging of brittle, elongated, and/or asymmetrically-shaped retail items for retail display to consumers. In some embodiments, the article of manufacture serves to protect the retail items from break... | 03/20/2012 |
| 8133876 | Oligomeric compounds and compositions for use in modulation of small non-coding RNAs Compounds, compositions and methods are provided for modulating the expression and function of small non-coding RNAs. The compositions comprise oligomeric compounds, targeted to small non-coding RNAs. Methods of using these compounds for modulation of small non-codi... | 03/13/2012 |
| 8133496 | Compositions and methods for diagnosing and treating urinary tract infections The present invention relates to methods and compositions for treating urinary tract infections. In particular, the present invention relates to vaccines and immune modulators for treating urinary tract infections. ... | 03/13/2012 |
| 8119742 | Multi-armed catechol compound blends The invention describes families of compounds that utilize multihydroxyl phenyl groups to provide adhesive properties. Selection of the multihydroxy phenyl group along with linkers or linking groups and the linkages between the linkers or linking groups with polyalk... | 02/21/2012 |
| 8119348 | Compositions and methods for diagnosing and treating macular degeneration The present invention relates generally to biomarkers for macular degeneration. In particular, the present invention provides a plurality of biomarkers for monitoring and diagnosing macular degeneration. The compositions and methods of the present invention find use... | 02/21/2012 |
| 8119336 | Compositions for use in identification of alphaviruses The present invention provides oligonucleotide primers and compositions and kits containing the same for rapid identification of alphaviruses by amplification of a segment of viral nucleic acid followed by molecular mass analysis. ... | 02/21/2012 |
| 8114835 | Self-assembling peptide amphiphiles for tissue engineering The present invention provides for compositions and methods for creating self-assembled peptide amphiphile (PA) structures. In particular, the present invention provides for two and three-dimensional structures of crosslinked PA microtexture structures useful for ti... | 02/14/2012 |
| 8114834 | Self-assembling peptide amphiphiles The present invention provides for self-assembling peptide amphiphiles that are capable of forming nanofibers. In particular, the present invention provides for diacetylene peptide amphiphiles that find use as scaffolds for tissue growth or for drug delivery. ... | 02/14/2012 |
| 8114599 | Compositions and methods for free-solution conjugate nucleic acid analysis The present invention provides compositions and methods for performing free-solution conjugate analysis of nucleic acid molecules. For example, the present invention provides multiplexed single-base extension assays for genotyping. In particular, the present inventi... | 02/14/2012 |
| 8110397 | Sample preparation apparatus A reconfigurable sample preparation device includes a rotary plunger device having a hollow body and a coupling device, provided above one end of the rotary plunger, and accommodating a sample. The device also includes at least one sealed reagent module. When the ro... | 02/07/2012 |
| 8101342 | DNA vaccine for treating or preventing cervical cancer comprising a gene encoding HPV protein Disclosed herein is a DNA vaccine for treating cervical cancer including an E5 gene of human papillomavirus (HPV). Also, disclosed is a combination DNA vaccine for preventing and treating cervical cancer including a gene encoding HPV L1 and/or L2 along with the HPV ... | 01/24/2012 |
| 8088749 | Compositions and methods for treating cancer The present invention relates to therapeutic targets for cancer. In particular, the present invention relates to small molecules and nucleic acids that target ATDC (TRIM29) expression in cancer with ATDC overexpression. ... | 01/03/2012 |
| 8084210 | Methods for the assessment of drug response The present invention provides methods for predicting or determining a subject's response to an antiplatelet agent, and methods for determining a subject's suitability to a treatment regime or intervention for a disease associated with platelet aggregation, using an... | 12/27/2011 |
| 8080643 | HPV primers The present invention provides methods, kits, and compositions related to human papillomavirus (HPV) primers, which may be used, for example, in nucleic acid detection assays for use in basic research, clinical research, and for the development of clinical detection... | 12/20/2011 |
| 8080262 | Encapsulated peptide amphiphile nanostructures The present invention provides compositions and methods for creating encapsulated peptide amphiphilic nanostructures useful in treating diseases. In particular, the present invention provides compositions and methods for preparing peptide amphiphile nanostructures t... | 12/20/2011 |
| 8071750 | Determination of hepatitis C virus genotype The present invention provides compositions and methods for the detection and characterization of HCV sequences. More particularly, the present invention provides compositions, methods and kits for using invasive cleavage structure assays (e.g. the INVADER assay) to... | 12/06/2011 |
| 8067188 | Analyte detection The present invention relates to analyte detection test systems, including test systems for the oral detection of analytes in saliva. The present invention also provides compositions and methods for storing multiple assay tests and compositions and methods for measu... | 11/29/2011 |
| 8063184 | RNA detection assays The present invention provides novel cleavage agents and polymerases for the cleavage and modification of nucleic acid. The cleavage agents and polymerases find use, for example, for the detection and characterization of nucleic acid sequences and variations in nucl... | 11/22/2011 |
| 8058003 | ADRB2 cancer markers The present invention relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present invention relates to ADRB2 markers for cancer. ... | 11/15/2011 |
| RE42931 | Covalent tethering of functional groups to proteins A mutant hydrolase optionally fused to a protein of interest is provided. The mutant hydrolase is capable of forming a bond with a substrate for the corresponding nonmutant (wild-type) hydrolase which is more stable than the bond formed between the wild-type hydrola... | 11/15/2011 |
| 8053187 | Linkers and co-coupling agents for optimization of oligonucleotide synthesis and purification on solid supports A method of modulation of synthesis capacity on and cleavage properties of synthetic oligomers from solid support is described. The method utilizes linker molecules attached to a solid surface and co-coupling agents that have similar reactivities to the coupling com... | 11/08/2011 |
| 8048622 | Identifying increased susceptibility to schizophrenia The present invention provides diagnostic markers of neuropsychiatric disorders (e.g., schizophrenia, schizoaffective disorder or serious mood disorders including bipolar disorder and recurrent unipolar disorder) for use in diagnosis, drug screening, therapy monitor... | 11/01/2011 |
| 8044259 | Determining the capability of a test compound to affect solid tumor stem cells A small percentage of cells within an established solid tumor have the properties of stem cells. These solid tumor stem cells give rise both to more tumor stem cells and to the majority of cells in the tumor that have lost the capacity for extensive proliferation an... | 10/25/2011 |
| 8043853 | Postnatal gut neural crest stem cells The present invention relates to compositions and methods employing postnatal (e.g., adult) neural crest stem cells. The stem cells are multipotent and differentiate when transplanted in vivo. Transplantation methods are provided for therapeutic, diagnostic, and res... | 10/25/2011 |
| 8039214 | Synthesis of tagged nucleic acids The present invention relates generally to methods, compositions and kits for synthesizing sense RNA molecules from one or more RNA molecules of interest in a sample. In exemplary embodiments, the methods use a terminal tagging oligoribonucleotide (rTTO) to join a D... | 10/18/2011 |
| 8034606 | Acid tolerant probio-65 with the ability of growth suppression of pathogenic microorganisms and the anti-allergic effect Disclosed are a novel tactic acid bacterium, Lactobacillus sakei Probio-65, and the use thereof. The L. sakei Probio-65 strain has acid tolerance, bile acid tolerance and antibiotic resistance, inhibits the growth of harmful pathogenic microorganisms i... | 10/11/2011 |
| 8030413 | Biomimetic compounds and synthetic methods therefor Synthesis methods for creating polymeric compounds comprising dihydroxyphenyl derivatives (DHPD), or DHPp i.e. polymers modified with DHPD, with desired surface active effects are described. The polymer backbone of DHPp has structural or performance features that ca... | 10/04/2011 |
| 8029782 | Therapeutic ribonucleases The present invention relates to the use of ribonucleases (RNases) in the treatment or prevention of disease. ... | 10/04/2011 |
| 8028640 | Compositions and methods for sealing The present invention relates to compositions and methods for creating insulating seals for use in a variety of applications, and to seals created by such compositions and methods. In particular, the present invention provides novel compositions and methods for crea... | 10/04/2011 |
