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| Number | Title | Issue Date |
| 8183269 | Process for the preparation of rufinamide The present invention relates to a process for the preparation of rufinamide of formula I, which process comprises: (i) reacting a 2,6-difluorobenzylhalide of formula II, wherein X is chloride, bromide or iodide, with an azide to obtain 2-(azidomethyl)-1,3-difluorob... | 05/22/2012 |
| 8183173 | Fast activating catalyst A method of preparing a catalyst comprising aging a silica support in an alkaline solution to produce an alkaline aged silica support, removing at least a portion of the alkaline solution from the alkaline aged silica support to produce a dried silica support, and a... | 05/22/2012 |
| 8178202 | Nonconcentric nanoshells with offset core in relation to shell and method of using the same A nanoparticle comprising a shell surrounding a core material with a lower conductivity than the shell material, wherein the core center is offset in relation to the shell center. A method comprising providing a nanoparticle comprising a nonconductive core and a con... | 05/15/2012 |
| 8170629 | Filter having impedance matching circuits A filter package is provided with a support structure, a filter device having terminals, impedance matching circuits formed on the support structure and electrically connected to at least some of the terminals of the filter device, and at least one electrical ground... | 05/01/2012 |
| 8168620 | Combination of azelastine and steroids A pharmaceutical product or formulation, which comprises azelastine or a pharmaceutically acceptable salt, solvate or physiologically functional derivative thereof, and a steroid, or a pharmaceutically acceptable salt, solvate or physiologically functional derivativ... | 05/01/2012 |
| 8164756 | System and method of fluid exposure and data acquisition An apparatus has a data acquisition device, an environmental cell in a spatial registration relative to the data acquisition device, the environmental cell being configured to support a sample, and a fluid management system configured to initiate and discontinue exp... | 04/24/2012 |
| 8163856 | Method and system to add high shear to improve an ionic liquid catalyzed chemical reaction In an embodiment, a method is disclosed to increase the activity of an ionic liquid catalyst comprising emulsifying the ionic liquid catalyst with one or more liquid components. In an embodiment, a method is disclosed comprising introducing into a reaction zone a mo... | 04/24/2012 |
| 8163723 | Combination of azelastine and steroids A pharmaceutical product or formulation, which comprises azelastine or a pharmaceutically acceptable salt, solvate or physiologically functional derivative thereof, and a steroid, or a pharmaceutical acceptable salt, solvate or physiologically functional derivative ... | 04/24/2012 |
| 8160217 | Systems, methods and apparatus for receipt printing and information display in a personal identification number delivery system Systems, methods, and apparatus for providing a personal identification number (PIN) in the form of a receipt displayed and/or printed by a client terminal are disclosed. A method includes storing, at the client terminal, receipt templates, received from a server, f... | 04/17/2012 |
| 8158780 | Processes for the preparation of ciclesonide and its crystal modification Improved processes for the synthesis of ciclesonide, chemically termed as [11β,16α(R)]-16,17-[(cyclohexylmethylene)bis(oxy)]-11-hydroxy-21-(2-methyl-1-oxopropoxy)pregna-1,4-diene-3,20-dione and its crystal modification. ... | 04/17/2012 |
| 8158726 | Poly(thioesters), their applications and derivatives The present invention provides poly(thioesters) and monomeric diesters, produced from di(hydroxyethyl)polysulfides and various mono- and di-basic carbonic acids or their anhydrides, and their derivatives. The new compounds combine properties of polyesters and polysu... | 04/17/2012 |
| 8158666 | Process for the preparation of (R)-5-(2-aminoethyl)-1-(6,8-difluorochroman-3-YL)-1,3-dihydroimidazole-2-thione A process for making (R)-5-(2-aminoethyl)-1-(6,8-difluorochroman-3-yl)-1,3-dihydroimidazole-2-thione and pharmaceutically acceptable salts thereof, and for making intermediates useful in the formation of said compound. ... | 04/17/2012 |
| 8153564 | Zirconium-based cross-linking composition for use with high pH polymer solutions A cross-linking composition comprising (a) an aqueous liquid; (b) a pH buffer; (c) a cross-linkable organic polymer; and (d) a solution of a zirconium cross-linking agent comprising the product of contacting a zirconium complex with an alkanolamine and ethylene glyc... | 04/10/2012 |
| 8152988 | Electrochemical process for the preparation of nitrogen fertilizers The present invention provides methods and apparatus for the preparation of nitrogen fertilizers including ammonium nitrate, urea, urea-ammonium nitrate, and/or ammonia, at low temperature and pressure, preferably at ambient temperature and pressure, utilizing a sou... | 04/10/2012 |
| 8147781 | Recovering metal values from a metalliferrous material There is provided a method of treating a metalliferrous material, comprising providing a metalliferrous material including at least one target metallic element, solubilising the metalliferrous material so as to effect production of an intermediate product including ... | 04/03/2012 |
| 8138278 | Polymer compositions and methods of making and using same A composition comprising a reaction product of reactants comprising (a) a compound comprising (i) a polysulfide moiety and (ii) an oxygen atom in a β-position to a sulfur link having the formula: where each R is independen... | 03/20/2012 |
| 8134360 | Measurement of pipe wall thickness using magnetic flux leakage signals An apparatus comprising a processor configured to implement a method comprising obtaining a pipe profile comprising a diameter, a nominal thickness, and a material, receiving a magnetic flux leakage (MFL) indication for a pipe associated with the pipe profile, and d... | 03/13/2012 |
| 8133996 | Process for the preparation of ethyl-N-(2,3-dichloro-6-nitrobenzyl)glycine hydrochloride The invention relates to a process for the preparation of anagrelide, and for the preparation of intermediates for use in preparing anagrelide. The invention also relates to the intermediates per se, in particular compounds of Formula (V): | 03/13/2012 |
| 8119203 | Method of treating a surface to protect the same A method of treating a substrate by applying a layer of at least one metal to the substrate to form an applied metal layer on the substrate and followed by curing of the applied metal layer at sub-atmospheric pressure to form a metal protective layer. A method of tr... | 02/21/2012 |
| 8114353 | Continuous catalyst activator Methods and systems for preparing catalyst, such as chromium catalysts, are provided. The valence of at least a portion of the catalyst sent to an activator is changed from Cr(III) to Cr(VI). The catalyst is prepared or activated continuously using a fluidization be... | 02/14/2012 |
| 8102532 | Resonant optothermoacoustic detection of optical absorption A device comprising an acoustic detector, one or more thermal sensing elements coupled to the acoustic detector, and a light source. A method comprising directing a beam of light at a wavelength at or near one or more thermal sensing elements, wherein the thermal se... | 01/24/2012 |
| 8099058 | Enhanced wideband transceiver A method for operating an integrated transceiver, comprising coupling an operating transmitter and an operating receiver within the integrated wideband receiver, inputting a signal into the operating transmitter, performing a first conversion of the signal, wherein ... | 01/17/2012 |
| 8098376 | Integrated embedded processor based laser spectroscopic sensor A novel low-power and compact laser spectroscopic sensor is described herein. Embodiments of the disclosed sensor utilize state-of-the-art microprocessors and digital processing techniques to reduce power consumption and integrate functions into a small device. In p... | 01/17/2012 |
| 8097764 | Methods of isomerizing xylenes with a catalyst reduced in the presence of hydrogen and a base A xylene isomerization process includes introducing gas comprising hydrogen and a base to a reaction zone in which a catalyst comprising a Group VIII metal and a zeolite support resides. In one embodiment, the base may be formed in situ within the reaction zone from... | 01/17/2012 |
| 8082754 | Jewelry fragrance dispenser A piece of jewelry to be worn by a wearer, having a spray mechanism mounted on the piece of jewelry, and a reservoir for containing a fluid mounted on the piece of jewelry, to dispense a fluid, such as a fragrance or scent, to the body of the wearer. The manipulatio... | 12/27/2011 |
| 8076492 | Process for preparing trityl olmesartan medoxomil and olmesartan medoxomil A process for the preparation of trityl olmesartan comprising (a) condensing 4-(1-hydroxy-1-methylethyl)-2-propyl-imidazol-5-carboxylic acid alkyl ester with trityl biphenyl bromide in the presence of a polar aprotic solvent and a base selected from the group consis... | 12/13/2011 |
| 8060156 | Filter having impedance matching circuits A filter package is provided with a support structure, a filter device having terminals, impedance matching circuits formed on the support structure and electrically connected to at least some of the terminals of the filter device, and at least one electrical ground... | 11/15/2011 |
| 8049052 | System and method of deactivating and quenching an oligomerization catalyst A method of deactivate a catalyst system is described. The method may include contacting a reactor effluent comprising a catalyst system, an oligomerized olefin, and diluent with a kill agent to at least partially deactivate the catalyst system, separating the react... | 11/01/2011 |
| 8045152 | All optical nanoscale sensor A composition comprising a nanoparticle and at least one adsorbate associated with the nanoparticle, wherein the adsorbate displays at least one chemically responsive optical property. A method comprising associating an adsorbate with a nanoparticle, wherein the nan... | 10/25/2011 |
| 8044002 | Solid zirconium-based cross-linking agent and use in oil field applications A solid zirconium cross-linking agent and use in a cross-linking composition in oil field applications such as hydraulic fracturing and plugging of permeable zones. The zirconium cross-linking agent is prepared by a process comprising contacting a zirconium complex ... | 10/25/2011 |
| 8044001 | Solid zirconium-based cross-linking agent and use in oil field applications A solid zirconium cross-linking agent is prepared comprising zirconium and hydroxyalkylated ethylene diamine ligand. Use of the cross-linking agent in compositions for oil field applications such as hydraulic fracturing and plugging of permeable zones is also disclo... | 10/25/2011 |
| 8043991 | Selective isomerization of olefins to alkenes using a mesoporous catalyst A process for selectively making 2-alkenes from a NAO using a mesoporous catalyst that has been surface modified with a Brönsted acid compound. The Brönsted acid compound has a reactive silane connector, an organic linking group, and a Brönsted acid group. The me... | 10/25/2011 |
| 8030491 | Process and intermediate for preparation of donepezil The invention relates to new compounds of formula (III): wherein R is a C1-C4 linear or branched alkyl group. The invention also relates to new compounds of formula (IV) | 10/04/2011 |
| 8017803 | Process for the preparation of tamsulosin and intermediates thereof A process for producing tamsulosin of formula I and pharmaceutically acceptable addition salts, thereof comprises the steps of: a) Reacting compound R,R-[2-(4-methoxy-phenyl)-1-methyl-ethyl]-(1-phenyl-ethyl)-am... | 09/13/2011 |
| 8009293 | Modulation cancellation method in laser spectroscopy Novel methods and laser spectroscopic systems for accurately measuring the concentration of compounds are disclosed herein. The disclosed methods utilize a modulation cancellation technique resulting in a significantly increase in the sensitivity and accuracy of las... | 08/30/2011 |
| 8007829 | Method to fabricate inhomogeneous particles A method for making inhomogeneous microparticles comprises a) providing an amount of each of at least two polyelectrolytes having a charge, b) providing an amount of a counterion having a valence of at least 2, c) combining the polyelectrolytes and the counterion in... | 08/30/2011 |
| 8006695 | Inhaler An inhaler device for inhalation of a medicament from a pierceable capsule comprises a housing for receiving a medicament capsule; closure means for closing the housing, said closure means being moveable relative to the housing; piercing means suitable for piercing ... | 08/30/2011 |
| 8003804 | Synthesis of 4-[1-(4-cyano phenyl)-(1,2,4-triazol-1-yl)methyl] benzonitrile and 4-[1-(1H-1,2,4-triazol-1-yl)methylene benzonitrile intermediate The present invention relates to a process for the preparation of 4-[1-(4-cyano phenyl)-1-(1,2,4-triazol-1-yl)methyl]benzonitrile (letrozole), substantially free from its isomeric impurity. The preparation involves reaction of 4-[1-(1H-1,2,4-triazol-1-yl)methylene b... | 08/23/2011 |
| 7999100 | Method for chiral inversion of (S)-(+)-and (R)-(−)-10,11-dihydro-10-hydroxy-5H-dibenz/b,f/azepine-5-carboxamide and optically enriched mixtures thereof A method for chiral inversion of optically pure or optically enriched mixtures of (S)-(+)-10,11-dihydro-10-hydroxy-5H-dibenz/b,f/azepine-5-carboxamide (I) and (R)-(−)-10,11-dihydro-10-hydroxy-5H-dibenz/b,f/azepine-5-carboxamide (II). ... | 08/16/2011 |
| 7998271 | Solvents and new method for the synthesis of CdSe semiconductor nanocrystals New methods for the synthesis of nanocrystals/quantum dots are disclosed. The methods comprise use of reasonably-priced and commercially available heat transfer fluids (such as Dowtherm® A) as solvents to synthesize CdSe nanocrystals. Separation of nucleation and g... | 08/16/2011 |
