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| Number | Title | Issue Date |
| 8183359 | Kits for amplifying DNA Kits for amplifying DNA which include a priming oligonucleotide that hybridizes to a 3′-end of a DNA target sequence, a displacer oligonucleotide that hybridizes to a target nucleic acid containing the DNA target sequence at a position upstream from the priming ol... | 05/22/2012 |
| 8105779 | Compositions and methods for detecting the presence of in a test sample The present invention describes novel oligonucleotides targeted to nucleic acid sequences derived from Cryptosporidium organisms, and Cryptosporidium parvum organisms in particular, which are useful for determining the presence of Cryptosporidium | 01/31/2012 |
| 8097409 | Kits for detecting group B Compositions, methods and kits for detecting Group B streptococci. Particularly described are oligonucleotides that are useful as amplification primers and hybridization probes for detecting very low levels of Group B streptococci nucleic acids. ... | 01/17/2012 |
| 8058006 | Method for obtaining and initiating amplification of a target nucleic acid sequence The present invention relates to oligonucleotides useful for determining the presence of Mycobacterium tuberculosis complex organisms in a test sample. The oligonucleotides of the present invention may be incorporated into detection probes, helper probes, cap... | 11/15/2011 |
| 8057762 | Penetrable cap A cap having a core structure dimensioned to receive a pipette therethrough. The cap includes two axially aligned frangible seals that are affixed to the core structure in a spaced-apart relationship. The frangible seals are constructed so that air passageways are f... | 11/15/2011 |
| 8052944 | Penetrable cap A cap having a core structure dimensioned to receive a pipette therethrough. The cap includes two axially aligned frangible seals that are affixed to the core structure in a spaced-apart relationship. The frangible seals include a foil layer and are constructed so t... | 11/08/2011 |
| 8038967 | Method for accessing the contents of a closed vessel containing a specimen retrieval device Method for obtaining a fluid from a collection device assembled to isolate a specimen retrieval device from the pathway of a fluid transfer device used to penetrate a cap of the collection device and to draw and remove the fluid from the collection device for analys... | 10/18/2011 |
| 8034570 | Tagged oligonucleotides and their use in nucleic acid amplification methods Disclosed are methods for selective amplification of target nucleic acid sequence using a tagged oligonucleotide comprising a target hybridizing sequence that hybridizes to a 3′-end of the target nucleic acid and a tag sequence situated 5′ to the target hybridiz... | 10/11/2011 |
| 8008017 | Compositions and methods for detecting the presence of cryptosporidium organisms in a test sample The present invention describes novel oligonucleotides targeted to nucleic acid sequences derived from Cryptosporidium organisms, and Cryptosporidium parvum organisms in particular, which are useful for determining the presence of Cryptosporidium | 08/30/2011 |
| 7939260 | Method for making available a priming oligonucleotide The present invention is directed to novel methods of synthesizing multiple copies of a target nucleic acid sequence which are autocatalytic (i.e., able to cycle automatically without the need to modify reaction conditions such as temperature, pH, or ionic strength ... | 05/10/2011 |
| 7927549 | Method for accessing the contents of a closed collection device with a modified pipette tip A method for accessing the contents of a closed collection device having a cap and a fluid-holding vessel in fixed association. The method includes penetrating one or more materials of the cap with an air displacement pipette, thereby forming one or more passageways... | 04/19/2011 |
| 7910067 | Sample tube holder A sample tube holder having sample tube compartments with sets of spaced finger springs provided therein for maintaining sample tubes in substantially upright orientations. A guide structure having a series of openings is used to direct sample tubes into the sample ... | 03/22/2011 |
| 7867777 | Method for obtaining sample material A sample carrier comprising a frame and one or more sample tube receiving structures pivotally connected to the frame. Each sample tube receiving structure includes a bottom member adapted to receive a plurality of sample tubes and a top member having a plurality of... | 01/11/2011 |
| 7858347 | Compositions and methods for determining the presence of in a test sample Oligonucleotides for use in determining the presence of Chlamydophila pneumoniae in a test sample. The oligonucleotides are incorporated into detection probes, capture probes, and amplification oligonucleotides, and can be used in various combinations thereof... | 12/28/2010 |
| 7833716 | Tagged oligonucleotides and their use in nucleic acid amplification methods A method for selective amplification of at least one target nucleic acid sequence, comprising the steps of: treating a sample with a tagged oligonucleotide comprising a target hybridizing sequence that hybridizes to a 3′-end of the target nucleic acid sequence, an... | 11/16/2010 |
| 7824922 | Method for removing a fluid substance from a closed system A cap which can form an essentially leak-proof seal with an open-ended vessel capable of receiving and holding fluid specimens or other materials for analysis. To minimize potentially contaminating contact between a fluid sample present in the vessel and humans or t... | 11/02/2010 |
| 7795036 | Method for accessing the contents of a closed collection device A method for obtaining the contents of a fluid-holding vessel having a cap secured to an open end thereof. The method includes penetrating a surface of the cap with a fluid transfer device and forming one or more air passageways between the penetrated surface of the... | 09/14/2010 |
| 7713697 | Methods and kits for amplifying DNA Novel methods of synthesizing multiple copies of a target nucleic acid sequence which are autocatalytic are disclosed (i.e., able to cycle automatically without the need to modify reaction conditions such as temperature, pH, or ionic strength and using the product o... | 05/11/2010 |
| 7708951 | Striated cap A cap for use in forming a sealed container with a fluid-holding vessel. The cap includes a downwardly tapered inner wall having a plurality of radially extending striations for improving the penetrability of the cap and for facilitating the formation of air passage... | 05/04/2010 |
| 7696337 | Composition kits and methods for performing amplification reactions The present invention is directed to novel methods of synthesizing multiple copies of a target nucleic acid sequence which are autocatalytic (i.e., able to cycle automatically without the need to modify reaction conditions such as temperature, pH, or ionic strength ... | 04/13/2010 |
| 7691332 | Penetrable cap A cap which can form an essentially leak-proof seal with an open-ended vessel capable of receiving and holding fluid specimens or other materials for analysis. To minimize potentially contaminating contact between a fluid sample present in the vessel and humans or t... | 04/06/2010 |
| 7648680 | Method for accessing the contents of a closed vessel containing a specimen retrieval device Method for obtaining a fluid sample from a collection device which includes assembling cap and fluid-holding vessel components of the collection device to contain and isolate a specimen retrieval device adjacent a side wall of the vessel. The position of the specime... | 01/19/2010 |
| 7632934 | Oligonucleotides for amplifying -derived nucleic acid Oligonucleotides useful for determining the presence of Trichomonas vaginalis in a test sample. The oligonucleotides may be incorporated into detection probes, helper probes, capture probes and amplification oligonucleotides, and used in various combinations ... | 12/15/2009 |
| 7611675 | Sample carrier having finger springs for holding sample tubes A sample carrier comprising a lower support wall, a base joined to or in fixed proximity to a bottom end of the lower support wall, and sample tube receiving areas in fixed proximity to the lower support wall for receiving and holding a plurality of sample tubes in ... | 11/03/2009 |
| 7592155 | Filter snapper A device for applying an axial compressive force to a fluid contamination detection system comprising a cup joined by a frangible connection to a filter ring, the force being sufficient to break the frangible connection and collapse a portion of the ring into the cu... | 09/22/2009 |
| 7587952 | Automated sampling system A sample carrier having a top wall, a base, and a support wall joining the top wall and the base. The top wall includes aligned, spaced-apart openings on at least one side of the support wall which are sized to receive sample tubes. Sleeves depending from the top wa... | 09/15/2009 |
| 7585631 | Method for obtaining purified RNA from viable oocysts The present invention describes novel oligonucleotides targeted to nucleic acid sequences derived from Crytosporidium organisms, and Crytosporidium parvum organisms in particular, which are useful for determining the presence of Cryptosporidium ... | 09/08/2009 |
| 7572588 | Modified probe molecules having self-complementary regions The present invention concerns oligonucleotides containing one or more modified nucleotides which increase the binding affinity of the oligonucleotides to target nucleic acids having a complementary nucleotide base sequence. These modified oligonucleotides hybridize... | 08/11/2009 |
| 7563579 | Method for detecting a structured target The present invention concerns oligonucleotides containing one or more modified nucleotides which increase the binding affinity of the oligonucleotides to target nucleic acids having a complementary nucleotide base sequence. These modified oligonucleotides hybridize... | 07/21/2009 |
| 7560256 | Automated process for detecting the presence of a target nucleic acid in a sample An automated process for detecting the presence of a target nucleic acid in a sample. The process includes separating the target nucleic acid from other material present in the sample at a first station, transferring the separated target nucleic acid from the first ... | 07/14/2009 |
| 7560255 | Automated process for detecting the presence of a target nucleic acid in a sample An automated process for detecting the presence of a target nucleic acid in a sample. The process includes contacting a sample with a magnetically-responsive solid support and immobilizing a target nucleic acid present in the sample on the solid support. At a first ... | 07/14/2009 |
| 7547516 | Method for reducing the presence of amplification inhibitors in a reaction receptacle An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations in which discrete aspects of the assay are performed on fluid samples contained in sample vessels. The analyzer includes stations for automatically preparing a ... | 06/16/2009 |
| 7524652 | Automated process for detecting the presence of a target nucleic acid in a sample An automated process performed in an analyzer for detecting the presence of a target nucleic acid in a sample. The process includes separating the target nucleic acid from other material present in the sample, performing an amplification reaction to produce an ampli... | 04/28/2009 |
| 7498137 | Compositions and methods for determining the presence of in a test sample The present invention relates to oligonucleotides useful for determining the presence of Chlamydophila pneumoniae in a test sample. The oligonucleotides of the present invention may be incorporated into detection probes, capture probes and amplification oligo... | 03/03/2009 |
| 7495093 | Amplification and detection method The present invention concerns oligonucleotides containing one or more modified nucleotides which increase the binding affinity of the oligonucleotides to target nucleic acids having a complementary nucleotide base sequence. These modified oligonucleotides hybridize... | 02/24/2009 |
| 7482143 | Automated process for detecting the presence of a target nucleic acid in a sample An automated process for detecting the presence of a target nucleic acid in a sample. The process is performed in a stand-alone unit and includes separating the target nucleic acid from other material present in the sample, engaging a robotic pipettor to combine the... | 01/27/2009 |
| 7470512 | Oligonucleotides for use in determining the presence of human papilloma virus in a test sample The present invention describes oligonucleotides targeted to HPV Type 16 and/or Type 18 nucleic acid sequences which are particularly useful to aid in detecting HPV type 16 and or 18. The oligonucleotides can aid in detecting HPV Type 16 and/or Type 18 in different ... | 12/30/2008 |
| 7435389 | Sealed collection device having striated cap A cap comprising a generally conical wall positioned beneath an opening in the cap and having a plurality of striations formed therein to facilitate penetration of the cap by a fluid transfer device. ... | 10/14/2008 |
| 7435576 | Filter snapper A device for applying an axial compressive force to a fluid contamination detection system comprising a cup joined by a frangible connection to a filter ring, the force being sufficient to break the frangible connection and collapse a portion of the ring into the cu... | 10/14/2008 |
| 7399852 | Kits and reaction mixtures containing modified probe molecules The present invention concerns oligonucleotides containing one or more modified nucleotides which increase the binding affinity of the oligonucleotides to target nucleic acids having a complementary nucleotide base sequence. These modified oligonucleotides hybridize... | 07/15/2008 |
