Bizarre Patents
Hands free towel carrying system
A hands free towel carrying system for coupling a towel to a user to prevent loss, theft or contamination.
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 6498165 | Src kinase inhibitor compounds Pyrimidine compounds (Formula I), or their pharmaceutically acceptable salts, hydrates, solvates, crystal forms and individual diastereomers, and pharmaceutical compositions including the same, which are inhibitors of tyrosine kinase enzymes, and as such ... | 12/24/2002 |
| 6380375 | DNA encoding monkey gonadotropin releasing hormone receptor The monkey GnRH receptor has been isolated, cloned and sequenced. The monkey GnRH receptor may be used to screen and identify compounds which bind to the GnRH receptor. Such identified compounds may be used in the treatment of sex hormone related conditio... | 04/30/2002 |
| 6353110 | Asymmetric conjugate addition reaction This invention relates to a key intermediate in the synthesis of an endothelin antagonist the synthesis of this key intermediate via an asymmetric conjugate addition reaction.... | 03/05/2002 |
| 6329380 | SRC kinase inhibitor compounds Pyrimidine compounds (Formula I), or their pharmaceutically acceptable salts, hydrates, solvates, crystal forms and individual diastereomers, and pharmaceutical compositions including the same, which are inhibitors of tyrosine kinase enzymes, and as such ... | 12/11/2001 |
| 6316444 | SRC kinase inhibitor compounds Pyrimidine compounds (Formula I), or their pharmaceutically acceptable salts, hydrates, solvates, crystal forms and individual diastereomers, and pharmaceutical compositions including the same, which are inhibitors of tyrosine kinase enzymes, and as such ... | 11/13/2001 |
| 6300356 | Method for decreasing QT dispersion or inhibiting the progression of QT dispersion with an angiotensin II receptor antagonist Angiotensin II receptor antagonists are useful for decreasing QT dispersion or inhibiting the progression of QT prolongation in patients. Also disclosed is a method for monitoring the reduction in die risk of experiencing an adverse cardiac event, such as... | 10/09/2001 |
| 6268510 | Rearrangement process and tricyclic and tetracyclic compounds A rearrangement process for the preparation of a 6,5,5-tricyclic, a 6,6,5-tricyclic and 6,5,5,7-tetracyclic ring system is disclosed.... | 07/31/2001 |
| 6268155 | Method for quantitating an inflammatory response A method for objectively quantitating the cellular infiltration in a tissue biopsy of a warm-blooded animal using a capture ELISA method. This method also allows one to quantitate the cellular infiltration of a tissue biopsy corresponding to an inflammato... | 07/31/2001 |
| 6268338 | Cyclohexapeptidyl amine compounds Cyclohexapeptidyl amine compounds are disclosed of the formula: ##STR1## or its acid addition salt, wherein: R1 is H or OH; R2 is H or OH; R3 is QCn H2n NRV RVI, QCn H2n | 07/31/2001 |
| 6251653 | Method of improved mixing of a varicella-infected cell culture in roller bottles A method for enhancing the mixing of a varicella-infected cell culture in a roller bottle by the introduction of controlled cross-sectional flow perturbations in roller bottle rotation is disclosed. The effectiveness of the method is demonstrated by achie... | 06/26/2001 |
| 6201002 | Method for reducing mortality with an angiotensin II antagonist Angiotensin II receptor antagonists are useful in reducing and preventing mortality and sudden cardiac death in symptomatic heart failure patients. Losartan potassium has been shown to reduce mortality and sudden cardiac death in this patient population. ... | 03/13/2001 |
| 6172235 | Asymmetric conjugate addition reaction This invention relates to a key intermediate in the synthesis of an endothelin antagonist and the synthesis of this key intermediate using an asymmetric conjugate addition reaction.... | 01/09/2001 |
| 6158438 | Model of heart failure A method of chronically instrumenting an animal enabling one to simulate congestive heart failure. This invention also relates to method for assessing the effects of a test compound on cardiac function and systemic vascular dynamics.... | 12/12/2000 |
| 6150554 | Oxidation process using periodic acid The present invention relates to an oxidation which converts a primary or secondary alcohol of Formula II: ##STR1## to an acid or ketone of Formula I: ##STR2## with periodic acid and a catalytic amount of a chromium reagent.... | 11/21/2000 |
| 6150357 | Potassium channel agonists This application discloses a method of treating cardiac ventricular arrhythmias and repolarization abnormalities associated with long QT syndrome and/or congestive heart failure comprising the adminstration of an agonist of the slowly activating cardiac d... | 11/21/2000 |
| 6127573 | Oxidaton of primary alcohols to carboxylic acids with a TEMPO catalyst using NaClO2 and NaClO The present invention relates to a TEMPO-catalyzed oxidation of primary alcohols, RCH2 OH to corresponding carboxylic acids, RCOOH in the presence of catalytic in the presence of catalytic amount of NaClO and stoichiometric amount of NaClO... | 10/03/2000 |
| 6121026 | Enantioselective bioreduction using yeast The invention relates to a class of enantiomerically pure intermediates represented by Formula I, where X is F, Cl, Br, or I, and a novel enantioselective bioreductive process using yeast to form these intermediates, which are useful in the synthesis of e... | 09/19/2000 |
| 6096544 | Method of improved mixing in roller bottles A method for enhancing the mixing of materials in a roller bottle by the introduction of controlled axial and cross-sectional flow perturbations is disclosed. The effectiveness of the method is demonstrated by achieving higher efficiency in cell culturing... | 08/01/2000 |
| 6087386 | Composition of enalapril and losartan The present invention discloses a pharmaceutical composition of enalapril and losartan and a pharmaceutically acceptable carrier.... | 07/11/2000 |
| 6046327 | Phosphate-mediated cyclization This invention relates to a cyclization process useful in the preparation of a key intermediate in the preparation of an endothelin antagonist of the general formula shown below: ##STR1##... | 04/04/2000 |
| 6031101 | Oxidation process using tempo The present invention relates to an oxidation using sodium chlorite in the presence of a catalytic amount of TEMPO and sodium hypochlorite which converts the penultimate intermediate bearing a primary alcohol to the target endothelin antagonist compound o... | 02/29/2000 |
| 6025500 | Stereoselective process for enalapril The invention relates to an improved stereoselective heterogenous catalytic reductive amination between ethyl 2-oxo-4-phenylbutyrate and alanylproline using hydrogen, a catalyst and one or more additives to produce the ACE inhibitor, enalapril.... | 02/15/2000 |
| 6015926 | Efficient enantioselective addition reaction using an organozinc reagent An efficient method for the preparation of key intermediate, in the synthesis of (-)-6-chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-2H-3,1-ben zoxazin-2-one, a reverse transcriptase inhibitor is achieved using a chiral addition reaction t... | 01/18/2000 |
| 5998625 | Asymmetric conjugate addition reaction using a chiral additive This invention relates to a process for the preparation of a key intermediate using an chiral additive to effect an asymmetric conjugate addition.... | 12/07/1999 |
| 5996426 | End-sampling thief probe This invention relates to an end-sampling thief probe and a method of using this probe. The thief probe of the invention is useful in extracting a sample with minimal disturbance and provides an improved method for end-sampling.... | 12/07/1999 |
| 5969017 | Methods of treating or preventing cardiac arrhythmia This application discloses a method of treating or preventing atrial arrhythmias which utilizes compounds which are blockers of the ultra-rapidly-activating delayed rectifier K+ current (IKur) of the human atrium in a use-dependent ... | 10/19/1999 |
| 5965729 | Process for the crystallization of a reverse transcriptase inhibitor using an anti-solvent The instant invention describes a method for crystallizing (-)-6-chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-2H-3,1-ben zoxazin-2-one from a solvent and anti-solvent solvent system and producing the crystalline product. The desired final crys... | 10/12/1999 |
| 5962500 | Insulin sensitivity with angiotensin II receptor blocking imidazoles This invention relates to a novel method of using an Angiotensin II antagonist for the improvement of insulin sensitivity alone or in conjunction with the treatment of hypertension. Angiotensin II antagonists such as the class of substituted imidazoles re... | 10/05/1999 |
| 5962688 | Stereoselective deoxygenation reaction This invention relates to a key intermediate in the synthesis of an endothelin antagonist, the synthesis of this key intermediate and the synthesis of an endothelin antagonist using this intermediate in a stereoselective deoxygenation reaction.... | 10/05/1999 |
| 5952528 | Process for enhancing the optical purity A process for enhancing the purity of 2R-1-hydroxy-1-trifluoromethyl-3-cyclopropylpropyn-2-yl!-4-chloroaniline comprising the formation of an acid addition salt which is capable of rejecting the racemate in the selected organic solvent.... | 09/14/1999 |
| 5938330 | Dynamically enhanced V-blender A study was done to compare the performance of a conventional V-blender to a V-blender that incorporates perturbations of the particle flow by rocking the mixing vessel during its normal rotation. Mixing was investigated using glass beads with sizes from ... | 08/17/1999 |
| 5935945 | Methods of treating or preventing cardiac arrhythmia A method of treating or preventing supraventricular tachyarrhythmias is disclosed which comprises the use of a compound which selectively blocks the ultra-rapidly-activating delayed rectifier K+ current (IKur) of the human atrium.... | 08/10/1999 |
| 5922864 | Efficient synthesis of a 1,4-dihydro2H-3,1-benzoxazin-2-one An efficient method for the preparation of a compound of (-)-6-chloro-4-cyclopropylethynyl-4-trifluoromethyl- 1,4-dihydro-2H-3, 1-benzoxazin-2-one, also known as DMP-266, a reverse transcriptase inhibitor is achieved using a cyclization reaction of the am... | 07/13/1999 |
| 5922906 | Side chains synthesis for an anthiarrhythmic compound The present invention is directed to an improved process for preparing the phenylacetic acid side chain of the compound of the formula ##STR1## This compound exhibits utility as a Class III antiarrhythmic agent.... | 07/13/1999 |
| 5906207 | Method for simulating heart failure A method of chronically instrumenting an animal enabling one to simulate congestive heart failure. A method for assessing the effects of a test compound on cardiac function and systemic vascular dynamics.... | 05/25/1999 |
| 5856492 | Efficient synthesis of a chiral mediator An efficient method for the quantitative preparation and isolation of a compound of formula I ##STR1## or its enantiomer, a chiral mediator used in enantioselective synthesis.... | 01/05/1999 |
| 5849914 | Compounds formed by an asymmetric conjugate addition reaction This invention relates to a key intermediate in the synthesis of an endothelin antagonist and the synthesis of this key intermediate using an asymmetric conjugate addition reaction.... | 12/15/1998 |
| 5811423 | Benzoxazinones as inhibitors of HIV reverse transcriptase Certain benzoxazinones are useful in the inhibition of HIV reverse transcriptase (including its resistant varieties), the prevention or treatment of infection by HIV and the treatment of AIDS, either as compounds, pharmaceutically acceptable salts, pharma... | 09/22/1998 |
| 5795904 | Enhanced functional recovery of the heart by losartan treatment after an ischemic attach Losartan, its active metabolite, EXP3174, or the pharmaceutically acceptable salts of these compounds for use in enhancing the functional recovery of the heart after an ischemic attack.... | 08/18/1998 |
| 5767310 | Phenoxyphenylacetic acid derivatives Phenoxyphenylacetic acids and derivatives of general structural formula (I) have endothelin antagonist activity and are useful in treating cardiovascular disorders, such as hypertension, postischemic renal failure, vasospasm, cerebral and cardiac ischemia... | 06/16/1998 |
