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Vehicular Impact Signaling Device
An apparatus for the deployment of a visible plume to alert other motorists that a proximate motor vehicle has been involved in a collision.
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| Number | Title | Issue Date |
| 8178550 | Hydrochloride salts of 8-[{1-(3,5-Bis-(trifluoromethyl)phenyl)-ethoxy)-methyl]-8-phenyl-1,7-diaza-spiro[4.5]decan-2-one and preparation process therefor Disclosed are hydrochloride and tosylate crystalline salt forms of (5S,8S)-8-[{(1R)-1-(3,5-Bis-(trifluoromethyl)phenyl)-ethoxy}-methyl]-8-phenyl-1,7-diazaspiro[4.5]decan-2-one, represented by Formula I and methods of preparing the same. ... | 05/15/2012 |
| 8162342 | Shock-absorbing suspension device for a wheeled vehicle A shock-absorbing suspension device includes a mounting rod adapted to be mounted on a frame of a wheeled vehicle, a wheel rod adapted to be mounted on a wheel axle to transmit a shock force generated as a result of movement of the vehicle over an uneven road surfac... | 04/24/2012 |
| 8158138 | Urea compositions and their methods of manufacture Urea compositions useful for treatment of dermatological conditions. The compositions, which are free from perceptible solids, may include at least about 50 wt-% urea, zinc pyrithione, and lactic acid, and may be formulated as a topical gel. ... | 04/17/2012 |
| 8137509 | Asymmetric synthesis of rocaglamides via enantioselective photocycloaddition mediated by chiral brønsted acids The present invention provides a new strategies for the synthesis of compounds of the rocaglamide family and related natural products. The synthetic approach generally involves photochemical generation of an oxidopyrylium species from a 3-hydroxychromone derivative ... | 03/20/2012 |
| 8132606 | Run-flat support system for a pneumatic tired wheel and method for installing same A run-flat support system and method for installing the same are disclosed. In one embodiment, the run-flat support system includes a torque assembly removably coupled to a split wheel rim of a pneumatic tired wheel. A plurality of support segments are adapted for a... | 03/13/2012 |
| 8114586 | Prevention and treatment of HCV infection employing antibodies directed against conformational and linear epitopes Conformational epitopes of the envelope proteins E1 and E2 of the Hepatitis C virus (HCV) have been identified and characterized using a panel of monoclonal antibodies derived from patients infected with HCV. These conserved conformational and linear epitopes of the... | 02/14/2012 |
| 8110590 | Synthesis of epothilones, intermediates thereto and analogues thereof The present invention provides compounds of formula (I): as described generally and in classes and subclasses herein. The present invention additionally provides pharmaceutical compositions comprisi... | 02/07/2012 |
| 8106193 | Luminophores There is described novel organo-platinum luminophores comprising a complex of formula (I). The luminophores have application as the emissive component in organic light emitting diodes. ... | 01/31/2012 |
| 8106098 | Protein conjugates with a water-soluble biocompatible, biodegradable polymer The present invention broadly relates to the field of protein modification, and, more specifically, to conjugates of proteins or analogs thereof to a water-soluble biocompatible polymer and methods of making and using the same. ... | 01/31/2012 |
| 8104434 | Electric tankless water heater In various aspects, the present invention provides an electric tankless liquid heater system capable of delivering liquid, such as, for example, water, with an acceptable increase in output liquid temperature upon a sudden and substantial decrease in liquid demand. ... | 01/31/2012 |
| 8101164 | Dual phase drug release system The present invention relates to conjugate comprising a carrier substituted with one or more occurrences of a moiety having the structure (I): wherein each occurrence of M is independently a modifier having a molecular weight ≦10 kDa; denotes direct of indirect at... | 01/24/2012 |
| 8093417 | Lipoxin analogs and methods for the treatment of periodontal disease This invention provides new lipoxin analogs, compositions containing analogs, and methods of using these compounds and compositions for treating and preventing oral inflammation, including gingivitis, periodontitis, and other forms of periodontal disease. The invent... | 01/10/2012 |
| 8093351 | Copolymerization of propylene oxide and carbon dioxide and homopolymerization of propylene oxide Copolymers of propylene oxide and carbon dioxide and homopolymers of propylene oxide are made using two dimensional double metal cyanide complexes having the formula Co[M(CN)4] or hydrated or partially dehydrated form thereof. There is no propylene carbon... | 01/10/2012 |
| 8064758 | Electric tankless water heater In various embodiments, the invention provides a system for heating a liquid, such as, for example, water, comprising a plurality of liquid heaters, the inlets and outlets of which are respectively connected in a parallel flow relationship by respective manifolds, a... | 11/22/2011 |
| 8043609 | Viral complement control proteins for eye disorders The present invention provides compositions and methods for treating and/or preventing age related macular degeneration and other conditions involving macular degeneration or choroidal neovascularization, ocular inflammation, or any combination of these. Certain of ... | 10/25/2011 |
| 8041157 | Silicon integrated photonic optical parametric amplifier oscillator and wavelength converter The present invention is directed towards systems and methods for adjusting intensity, wavelength and higher and lower frequency components of an optical signal. Photonic apparatus receives a first and a second optical signal. A waveguide provides an anomalous group... | 10/18/2011 |
| 8035361 | Boost device for voltage boosting A boost device boosts an input voltage to an output voltage across an output capacitor, and includes first and second output diodes coupled to the output capacitor, and a transformer coupled to first and second switches, first and second switching circuits, and to t... | 10/11/2011 |
| 8026364 | NKantagonists A compound having the general structure shown in Formula I: or pharmaceutically acceptable salt and/or solvates thereof are useful in treating diseases or conditions mediated by NK1 receptors, for example various... | 09/27/2011 |
| 7989465 | 4,6-disubstituted pyrimidines useful as kinase inhibitors The present invention provides 4,6-disubstituted pyrimidine compounds useful as kinase inhibitors, pharmaceutically acceptable salts and compositions thereof, and methods of using the same. The present invention also provides probe compounds, such as compounds of fo... | 08/02/2011 |
| 7988763 | Use of a binary salt flux of NaCl and MgClfor the purification of aluminium or aluminium alloys, and method thereof A method for the purification of a metal selected from the group consisting of aluminum and aluminum alloys, wherein the metal is in a liquid phase and is contacted with a salt flux consisting of a binary mixture of NaCl and MgCl2. Preferably, more than 2... | 08/02/2011 |
| 7982036 | 4,6-disubstitued pyrimidines useful as kinase inhibitors The present invention provides compounds of formula I wherein Ring A, Ring B, m, Rx, Ry, W and R1 are as defined herein, pharmaceutically acceptable salts and compositions thereof, and metho... | 07/19/2011 |
| 7981905 | Pharmaceutical formulations: salts of 8-[{1-(3,5-bis-(trifluoromethyl)phenyl)-Ethoxy}-methyl]-8-phenyl-1,7-diaza-spiro[4.5]decan-2-one and treatment methods using the same Pharmaceutical formulations containing salts of (5S,8S)-8-[{(1R)-1-(3,5-Bis-(trifluoromethyl)phenyl]-ethoxy}-methyl]-8-phenyl-1,7-diazaspiro[4.5]decan-2-one, represented by Formula I, are disclosed. Disclosed also are methods of treatment utilizing such dosage forms... | 07/19/2011 |
| 7968536 | Heterocyclic compounds useful as RAF kinase inhibitors The present invention provides compounds useful as inhibitors of protein kinase. The present invention also provides compositions thereof, and methods of treating Raf-mediated diseases. ... | 06/28/2011 |
| 7956657 | Time delay apparatus A time delay apparatus for generating a plurality of phase shifted signals is described comprising a phase tuner generating a phase control signal and a phase interpolator receiving at least one digital signal and generating the plurality of phase shifted signals by... | 06/07/2011 |
| 7951898 | Biodegradable polyketal polymers and methods for their formation and use The present invention relates to biodegradable biocompatible polyketals, methods for their preparation, and methods for treating animals by administration of biodegradable biocompatible polyketals. In one aspect, a method for forming the biodegradable biocompatible ... | 05/31/2011 |
| 7947487 | Multifunctional encoded particles for high-throughput analysis Method for making multifunctional particles. The method includes flowing a first monomer stream loaded with a fluorescent entity along a microfluidic channel and flowing a second monomer stream loaded with a probe adjacent to the first monomer stream along the micro... | 05/24/2011 |
| 7947436 | Polynucleotides and polypeptide sequences involved in the process of bone remodeling This invention relates, in part, to unique and newly identified genetic polynucleotides involved in the process of bone remodeling; variants and derivatives of the polynucleotides and corresponding polypeptides; uses of polynucleotides, polypeptides, variants and de... | 05/24/2011 |
| 7947267 | Viral complement control proteins for eye disorders The present invention provides compositions and methods for treating and/or preventing age related macular degeneration and other conditions involving macular degeneration or choroidal neovascularization. Certain of the compositions comprise a poxvirus complement co... | 05/24/2011 |
| 7943597 | Phosphate-binding chitosan and uses thereof The present invention provides compositions and methods for removing phosphate from a subject using chitosan. The present invention also provides compositions and methods for treating hyperphosphatemia based on phosphate-binding chitosan. ... | 05/17/2011 |
| 7532134 | Systems and methods for sharing compression histories between multiple devices Systems and methods of storing previously transmitted data and using it to reduce bandwidth usage and accelerate future communications are described. By using algorithms to identify long compression history matches, a network device may improve compression efficient... | 05/12/2009 |
| 7531191 | Stimuli-responsive systems for controlled drug delivery A method of delivering a therapeutic agent by providing a cross-linked polymer encapsulating the therapeutic agent to a site in a patient. The degradation rate of the cross-linked polymer is correlated with a local concentration of an indicator, and the therapeutic ... | 05/12/2009 |
| 7531181 | Gp120 specific antigens and uses thereof The present invention provides multi-antigenic constructs comprising one or more carbohydrate antigens having the formula: wherein R1, R2A, R2B | 05/12/2009 |
| 7517422 | Non-vinyl flooring and method for making same In one embodiment or the present invention, a non-vinyl flooring is described comprising a flooring substrate having a non-vinyl composition comprising a terpolymer comprising ethylene, methyl acrylate and acrylic acid and a copolymer comprising ethylene and methacr... | 04/14/2009 |
| 7514237 | Systems and methods for protein production The invention relates to systems and methods for producing proteins of interest. The invention employs genetically-engineered animal or plant cells that have modified protein folding or processing capacities. In one aspect, the invention features genetically-enginee... | 04/07/2009 |
| 7502784 | Method and system for efficiently reducing graphical display data for transmission over a low bandwidth transport protocol mechanism The present invention improves the performance of distributed systems by reducing the amount of graphical data transmitted between an application server and a thin client. The encoding technique used for graphical data is adapted in response to the repetitiveness of... | 03/10/2009 |
| 7502726 | Systems and methods for maintaining a session between a client and host service The invention relates to methods and systems for reconnecting a client and providing user authentication across a reliable and persistent communication session. A first protocol that encapsulates a plurality of secondary protocols is used to communicate over a netwo... | 03/10/2009 |
| 7498023 | Blockade of T cell migration into epithelial GVHD target tissues as an approach to achieving anti-tumor effects against lymphohematopoietic malignancies without GVHD Antagonists of T cell migration are used to reduce GVHD in recipients of hematopoietic cell grafts. The administration of antagonists of T cell migration can be used in combination with conventional methods of bone marrow transplantation and in combination with the ... | 03/03/2009 |
| 7490508 | Bench scale apparatus to model and develop biopharmaceutical cleaning procedures An apparatus for testing a cleaning procedure for a material. The apparatus includes a rack having a seat configured to retain a plurality of test coupons at a predetermined angle, an upper tray that distributes a solution along the lines of the rack, a lower tray f... | 02/17/2009 |
| 7493050 | Optical communication system having an antiresonant dispersion map suppressing four wave mixing and cross phase modulation An optical communication system transmitting a plurality of channel wavelengths is provided. The system includes a transmitter unit, a receiver unit, and an optical transmission path interconnecting the transmitter and receiver units. The transmission path has a con... | 02/17/2009 |
