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| Number | Title | Issue Date |
| 8182679 | Organosilanes and substrate bonded with same The present invention, provides novel silicon compounds, methods for making these novel silicon compounds, compositions comprising these novel silicon compounds attached to substrates, methods for attaching the novel silicon compounds to substrates and methods for u... | 05/22/2012 |
| 8133373 | Electrochemically driven pump A continuous electrochemical pump comprising a water generator compartment, an anode compartment on one side of said generator compartment, a cation exchange barrier, separating the generator compartment from the anode compartment, a first electrode in electrical co... | 03/13/2012 |
| 8101422 | Multidimensional chromatography apparatus and method An ion chromatography apparatus comprising: (a) a first chromatography column, (b) a second chromatography column, the volume of the second column being no greater than 0.9 times the volume of the first; and (c) valving disposed between said first and second columns... | 01/24/2012 |
| 8062515 | Parking a sample stream and suppressing the sample Pretreatment method and apparatus to remove matrix ions from a liquid sample, prior to separation of the sample analytes (e.g. by chromatography), by flowing the liquid sample into a sample compartment and stopping the flow. The sample compartment has a wall compris... | 11/22/2011 |
| 8043507 | Ion chromatography system using catalytic gas elimination A liquid chromatographic system is provided including catalytically combining hydrogen and oxygen gases in the chromatography eluent stream in a catalytic gas elimination chamber, to form water and thereby reduce the gas content in the eluent stream. Also, a liquid ... | 10/25/2011 |
| 8021555 | Recycled suppressor regenerants A suppressed ion chromatographic apparatus using a regenerant recycle loop, comprising (a) an ion separation device, (b) a membrane suppressor, (c) a detector, (d) a container for regenerant solution, (e) a first conduit between the ion separation device and the sup... | 09/20/2011 |
| 8017173 | Dehydrated mash potato product and process Dehydrated potato pellets are made by preparing an aqueous mixture of dried potato pieces, an emulsifier, and oil, and, optionally, a freshly cooked potato, homogenizing the mixture to produce a pumpable, flowable aqueous dispersion, mixing the dispersion with more ... | 09/13/2011 |
| 7972781 | Detection of DNA damage The health condition of a living organism is detected by electrochemically analyzing samples from selected areas of the body of said living organism for elevated free levels of nucleotide excision products resulting from DNA or RNA damage. ... | 07/05/2011 |
| 7964411 | Membrane based concentrators A sample concentrator for concentrating analytes in a solvent-containing liquid sample stream, including concentrator housing having a sample stream flow channel and a gas stream flow channel having an inlet and an outlet, a heater for gas in the gas stream conduit,... | 06/21/2011 |
| 7922909 | Separation system, components of a separation system and methods of making and using them Permeable polymeric monolithic materials are prepared in a column casing. In one embodiment, the permeable polymeric monolithic materials are polymerized while pressure is applied through a piston having a smooth piston head in contact with the polymerization mixtur... | 04/12/2011 |
| 7922908 | Separation system, components of a separation system and methods of making and using them Permeable polymeric monolithic materials are prepared in a column casing. In one embodiment, the permeable polymeric monolithic materials are polymerized while pressure is applied through a piston having a smooth piston head in contact with the polymerization mixtur... | 04/12/2011 |
| 7879385 | Emulsified bean-based oil substitute A method for making a bean-based oil substitute comprising the steps of making an aqueous liquid dispersion of comminuted beans in a stable flowable form, homogenizing said aqueous dispersion, and mixing an emulsifier with said comminuted beans before, during or aft... | 02/01/2011 |
| 7780834 | Apparatuses and methods for electrochemically modifying the retention of species on chromatography material An apparatus and method for electrochemically modifying the retention of a species on a chromatography material is disclosed. The apparatus comprises a housing having an effluent flow channel adapted to permit fluid flow therethrough. The effluent flow channel compr... | 08/24/2010 |
| 7767462 | Electrolytic eluent generator and method of use An acid or base is generated in an aqueous solution by the steps of: (a) providing a source of first ions adjacent an aqueous liquid in a first acid or base generation zone, separated by a first barrier (e.g., anion exchange membra... | 08/03/2010 |
| 7704749 | Aqueous stream purifier and method of use An electrolytic method is provided for purifying an aqueous stream, including at least one contaminant ion. In one embodiment, the eluent stream flows through a purifying flow channel, including ion exchange bed, an electric field is applied through the flowing elue... | 04/27/2010 |
| 7682506 | IC system including sample pretreatment and using a single pump An IC system including sample preparation. The system includes a liquid sample injection loop, an ion concentrator, an ion separator, and only a single pump for pumping fluid through the system. ... | 03/23/2010 |
| 7643967 | Method of designing fold lines in sheet material A method of designing fold lines in sheet material includes the steps defining the desired fold line in a parent plane on a drawing system, and populating the fold line with a fold geometry including a series of cut zones that define a series of connected zones conf... | 01/05/2010 |
| 7640775 | Apparatus and method for joining the edges of folded sheet material to form three-dimensional structure A sheet of material formed for folding into a three-dimensional structure. The sheet has edges formed with joinder structures, such as dovetails, and a plurality of folding structures, such as slits, grooves or displacements, that control folding of the sheet in a m... | 01/05/2010 |
| 7632404 | Barrier with a seated ion exchange bead and method Ion transport apparatus (e.g. an electrolytic eluent generator or a suppressor for ion chromatography) in which ions in a first chamber are transported to a liquid in second chamber through a wall comprising an ion exchange bead sealed in a bead seat. The wall is ca... | 12/15/2009 |
| 7618826 | Membrane suppressor with an outlet substantially non-retentive for ionic species An apparatus for ion chromatography comprising a suppressor comprising a housing and a liquid conduit segment disposed in the housing, the liquid conduit segment including a membrane, the membrane having an inlet section adjacent the inlet of the conduit segment and... | 11/17/2009 |
| 7618535 | Suppressed chromatography and salt conversion system Method and apparatus for suppressed ion analysis in which a sample solution of analyte (e.g., anion) in an eluent of electrolyte counterions (e.g., sodium), is chromatographically separated. Then, the counterions are suppressed in a suppression zone and removed and ... | 11/17/2009 |
| 7615610 | Modified trafficking patterns for arrestin and G-protein-coupled receptors via arrestin-ubiquitin chimera The present invention relates to a modified arrestin which includes an arrestin molecule and a ubiquitin molecule. This modified arrestin has an increased affinity for a GPCR, and traffics with the GPCR into endosomes. The present invention further relates to a meth... | 11/10/2009 |
| 7585679 | Ion chromatography system with flow-delay eluent recycle A chromatographic method including chromatographically separating sample ionic species in an eluent stream, detecting the separated sample ionic species, catalytically combining hydrogen and oxygen gases or catalytically decomposing hydrogen peroxide in a catalytic ... | 09/08/2009 |
| 7582482 | Continuous ion species removal device and method Apparatus and method for treating a liquid sample stream including at least one analyte ion species and matrix ion species of opposite charge to said one analyte ion species. The liquid sample stream flows through a treatment channel. A carrier liquid stream includi... | 09/01/2009 |
| 7572888 | Methods of assaying receptor activity and constructs useful in such methods Described are methods of detecting G-protein coupled receptor (GPCR) activity in vivo and in vitro; methods of assaying GPCR activity; and methods of screening for GPCR ligands, G protein-coupled receptor kinase (GRK) activity, and compounds that interact with compo... | 08/11/2009 |
| 7566392 | Pulsed electrochemical detection method In one embodiment, the present invention is directed to a pulsed electrochemical detection method comprising (a) flowing a liquid sample stream including at least one analyte past a working electrode in a flow-through cell; (b) applying at least three pulsed electri... | 07/28/2009 |
| 7560155 | Sheet material with bend controlling grooves defining a continuous web across a bend line and method for forming the same A sheet of material (21, 61, 81) formed for control bending along a bend line (23, 63) while maintaining a continuous web of material (26) across the bend line (23, 63). The sheet has at least one groove (22, 62, 82) formed therein... | 07/14/2009 |
| 7557232 | Compositions useful as chromatography stationary phases The current invention provides compositions, which are useful as stationary phases for a variety of chromatographic applications, such as high performance liquid chromatography (HPLC). The compositions include a substrate (e.g., silica gel), covalently bound to a co... | 07/07/2009 |
| 7541151 | Single-cell biosensor for the measurement of GPCR ligands in a test sample The present invention is related to the detection of GPCR ligands in a test sample by using a single cell biosensor expressing a GPCR. Preferably, the test sample is derived from a biological or environmental sample. This invention may be used to detect the presence... | 06/02/2009 |
| 7534501 | Precision-folded, high strength, fatigue-resistant structures and sheet therefor Precision-folded, high strength, fatigue-resistant structures and a sheet therefore are disclosed. To form the structures, methods for precision bending of a sheet of material along a bend line and a sheet of material formed with bending strap-defining structures, s... | 05/19/2009 |
| 7531075 | Method and apparatus for generating a high purity eluant An apparatus and method for electrochemically modifying the retention of a species on a chromatography material is disclosed. The apparatus comprises a housing having an effluent flow channel adapted to permit fluid flow therethrough. The effluent flow channel compr... | 05/12/2009 |
| 7524457 | Displacement chemical regeneration method and apparatus Apparatus for chromatographically separating ionic species in an aqueous electrolyte-containing eluent to form an effluent, suppressing the effluent, detecting the suppressed effluent and passing the detected effluent to a regenerant reservoir, thereby displacing th... | 04/28/2009 |
| 7517696 | Chemical suppressors and method of use A non-electrolytic method and apparatus for treating an aqueous sample stream including analyte ions and matrix ions of opposite charge, for pretreatment or suppression. The apparatus includes an ion exchange membrane capable of passing only ions of opposite charge ... | 04/14/2009 |
| 7515259 | Flow cell for optical detector and method of forming same A flow cell for optical detector includes a flow cell body, a face-seal window, and a pressed illumination window. The flow cell body is formed of an inert material and includes large and small bores, and inlet and outlet passageways in fluid communication with the ... | 04/07/2009 |
| 7473354 | Recycled suppressor regenerants A suppressed ion chromatographic apparatus using a regenerant recycle loop, comprising (a) an ion separation device, (b) a membrane suppressor, (c) a detector, (d) a container for regenerant solution, (e) a first conduit between the ion separation device and the sup... | 01/06/2009 |
| 7473367 | Monolithic column Permeable polymeric monolithic materials are prepared in a plastic column casing. In one embodiment, the permeable polymeric monolithic materials are polymerized by the application of heat from an external source starting at a low temperature such as 40 degrees cent... | 01/06/2009 |
| 7468130 | Organosilanes and substrates covalently bonded with same and methods for synthesis and use same The present invention provides novel silicon compounds, methods for making these novel silicon compounds, compositions comprising these novel silicon compounds attached to substrates, methods for attaching the novel silicon compounds to substrates and methods for us... | 12/23/2008 |
| 7464574 | Method for forming sheet material with bend facilitating structures into a fatigue resistant structure A process for designing and manufacturing precision-folded, high strength, fatigue-resistant structures and a sheet therefore. The techniques include methods for precision bending of a sheet of material (41, 241, 341, 441, 541) along a bend line (45, 245, ... | 12/16/2008 |
| 7455982 | Automated methods of detecting receptor activity Methods of detecting G protein-coupled receptor (GPCR) activity in vitro and in vivo are provided. In one embodiment, the method includes providing at least one cell that expresses a GPCR and a plurality of conjugated proteins. Each of the plurality of conjugated pr... | 11/25/2008 |
| 7454959 | Method and device for providing defined fluid flow, especially for use in liquid chromatography The invention relates to a method for providing a defined fluid flow, especially for use in liquid chromatography. According to the method, a constant total flow (f0) is subdivided into an internal excess flow (fie) in an excess branch and into... | 11/25/2008 |
