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| Number | Title | Issue Date |
| 8173425 | Fusion partner cells Fusion partner cells that enable production of heterohybridomas even from cells of species other than mouse were produced by fusing myeloma cells derived from a first animal species with leukemia cells derived from a second animal species, which have an extra S phas... | 05/08/2012 |
| 8168408 | Cytolethal distending toxins and detection of bacteria using the same as a target The present inventors succeeded in cloning the CDT genes of C. coli and C. fetus, which were previously unknown, and in determining their sequences. In addition, the inventors also developed specific primers and primers common to the two species by com... | 05/01/2012 |
| 8167040 | In situ combustion in gas over bitumen formations The invention provides methods for natural gas and oil recovery, which include the use of air injection and in situ combustion in natural gas reservoirs to facilitate production of natural gas and heavy oil in gas over bitumen formations. ... | 05/01/2012 |
| 8162918 | Gels with predetermined conductivity used in electroporation of tissue Gel compositions with adjusted conductivity are disclosed which compositions are used for directing reversible electroporation and irreversible electroporation of cells and tissue. The gel compositions are also used in a similar manner in order to carry out thermoth... | 04/24/2012 |
| 8138157 | Antibiotic formulation and method of treatment A formulation comprised of particles which may be in groups and are comprised of a biocompatible polymer and an antimicrobial drug for controlled release of the drug is disclosed. The particles may be in an aqueous solution comprising thrombin and be dispersed in a ... | 03/20/2012 |
| 8119156 | Dual action, inhaled formulations providing both an immediate and sustained release profile Methods for formulating immediate and sustained release anti-infectives and delivery of such for treatment of respiratory tract infections and other medical conditions, and devices and formulations used in connection with such are described. ... | 02/21/2012 |
| 8118771 | Needleless injector drug capsule and a method for filling thereof A method for filling needleless injector capsules with liquid drug, whereby dissolved gas within the drug is replaced by a less soluble gas in order to reduce the inclusion of gas bubbles, or to prevent the growth of bubbles during storage and thereby prevent breaka... | 02/21/2012 |
| 8101421 | Volumetric induction phase shift detection system for determining tissue water content properties A method of determining the condition of a bulk tissue sample, by: positioning a bulk tissue sample between a pair of induction coils (or antennae); passing a spectrum of alternating current (or voltage) through a first of the induction coils (or antennae); measurin... | 01/24/2012 |
| 8097430 | Antigen targeting The present invention provides a method of raising an immune response in an animal. The method comprises administering to the animal a composition comprising a carrier and an antigen bound to a targeting moiety wherein the targeting moiety binds to at least one rece... | 01/17/2012 |
| 8071367 | Selecting, culturing and creating lineage committed hematopoietic stem cells The present invention provides a method for selecting hematopoietic stem cells (HSCs) comprising providing an agent which binds to α9β1 integrin on the cell surface to a population of cells including HSCs and separating HSCs by virtue of the binding agent. The inv... | 12/06/2011 |
| 8071127 | Dual action, inhaled formulations providing both an immediate and sustained release profile Methods for formulating immediate and sustained release anti-infectives and delivery of such for treatment of respiratory tract infections and other medical conditions, and devices and formulations used in connection with such are described. ... | 12/06/2011 |
| 8066661 | Viscous formulations and their use in needle-free injection Formulations are described that are viscous and will benefit from needle-free delivery at high driving pressures. Conventional delivery of these viscous formulations by hypodermic syringes is inconvenient as well as painful. Formulations include those which have a v... | 11/29/2011 |
| 8048067 | Tissue ablation with irreversible electroporation A new method for the ablation of undesirable tissue such as cells of a cancerous or non-cancerous tumor is disclosed. It involves the placement of electrodes into or near the vicinity of the undesirable tissue through the application of electrical pulses causing irr... | 11/01/2011 |
| 7958887 | Nozzle pore configuration for intrapulmonary delivery of aerosolized formulations The present invention describes the configuration of a porous sheet for improving the efficiency for generating an aerosol from a liquid formulation. This aerosolized liquid formulation can be used for intrapulmonary delivery of pharmaceutically active drugs and dia... | 06/14/2011 |
| 7955827 | Controlled electroporation and mass transfer across cell membranes Electroporation is performed in a controlled manner in either individual or multiple biological cells or biological tissue by monitoring the electrical impedance, defined herein as the ratio of current to voltage in the electroporation cell. The impedance detects th... | 06/07/2011 |
| 7952705 | Integrated microfluidic optical device for sub-micro liter liquid sample microspectroscopy The present disclosure relates to the fields of microchips with microfluidic optical chambers for multiplexed optical spectroscopy. Embodiments of the present invention allow for ultra small sample volume, as well as high detection speed and throughput, as compared ... | 05/31/2011 |
| 7910374 | Volumetric induction phase shift detection system for determining tissue water content properties A method of determining the condition of a bulk tissue sample, by: positioning a bulk tissue sample between a pair of induction coils (or antennae); passing a spectrum of alternating current (or voltage) through a first of the induction coils (or antennae); measurin... | 03/22/2011 |
| 7901385 | Casing A casing (50) for an injection device (10) of the type having a safety device which prevents operation of the device (10), incorporating an actuator means (56) by which the safety means of the device (10) can be actuated to allow o... | 03/08/2011 |
| 7900701 | In situ combustion in gas over bitumen formations The invention provides methods for natural gas and oil recovery, which include the use of air injection and in situ combustion in natural gas reservoirs to facilitate production of natural gas and heavy oil in gas over bitumen formations. ... | 03/08/2011 |
| 7879983 | Binding member which binds to both Lewis-and Lewis-haptens, and its use for treating cancer The invention relates to the use of a binding member which binds to Lewisy and Lewisb haptens in the treatment of tumours and leukaemia. The binding member may be an antibody which binds to Lewisy and Lewisb haptens and ca... | 02/01/2011 |
| 7879805 | High temperature stable peptide formulation A stabilized pharmaceutical composition in the form of a lyophilized product to be later reconstituted to generate an aqueous drug product is described herein. The therapeutically active ingredient in the form of a peptide of sequence TDLQERGDNDISPFSGDGQPFKD is stab... | 02/01/2011 |
| 7812015 | Prophylaxis and treatment of infectious diseases The invention relates to the use of inhibitors of acid sphingomyelinase and/or of inhibitors of products of the reaction catalyzed by this enzyme, for the prophylaxis and/or treatment of infectious diseases and/or diseases which are influenced by infections during t... | 10/12/2010 |
| 7776007 | Device for readying a needle free injector for delivery A needle-free injector device comprising a latch having a safe position which disables the triggering of the device, and a ready position which restrains movement of a dispensing member but enables triggering and a triggered position which permits movement of the di... | 08/17/2010 |
| 7767930 | Method and system for LASER machining The invention provides a method of rapidly machining multiple, often similar or nearly identical, features using a LASER machining system. During LASER machining, light of a wavelength and intensity that will modify the workpiece to be machined is directed at the wo... | 08/03/2010 |
| 7745613 | Method for preparing peritoneal dialysate Carbonyl compounds generated and accumulated in the peritoneal dialysate can be inactivated or eliminated by a carbonyl compound-trapping agent such as aminoguanidine. Carbonyl compounds generated during sterilization and storage of the peritoneal dialysate can be e... | 06/29/2010 |
| 7736641 | Role for SRY in Parkinson's disease The present invention relates to a method for treating or preventing Parkinson's disease in a patient, the method comprising administering to the patient a therapeutically effective population of neuronal cells transformed with a nucleic acid molecule encoding SRY, ... | 06/15/2010 |
| 7718409 | Controlled electroporation and mass transfer across cell membranes Electroporation is performed in a controlled manner in either individual or multiple biological cells or biological tissue by monitoring the electrical impedance, defined herein as the ratio of current to voltage in the electroporation cell. The impedance detects th... | 05/18/2010 |
| 7718379 | Identifying haematopoietic stem cells based on cell surface markers The present invention relates to a method of identifying a haematopoietic stem cell (HSC) or progeny thereof comprising the steps of: obtaining a cell sample including HSC or progeny thereof; detecting the presence of at least one carbohydrate sequence having a sequ... | 05/18/2010 |
| 7718376 | Identification and isolation of somatic stem cells and uses thereof The present invention relates to the identification of a specific population of cell types, in particular somatic stem cells including haematopoietic stem cells, mesenchymal stem cells and keratinocyte stem cells. The invention also provides for methods of isolation... | 05/18/2010 |
| 7674249 | Gels with predetermined conductivity used in electroporation of tissue Gel compositions with adjusted conductivity are disclosed which compositions are used for directing reversible electroporation and irreversible electroporation of cells and tissue. The gel compositions are also used in a similar manner in order to carry out thermoth... | 03/09/2010 |
| 7655760 | Antibodies to the polypeptide hormone phosphatonin The present invention relates to a novel human protein called phosphatonin, and isolated polynucleotides encoding this protein. Also provided are vectors, host cells, antibodies, and recombinant methods for producing this human protein. The invention further relates... | 02/02/2010 |
| 7638486 | Method for promoting hard tissue formation Formulations and methods to promote biological processes to form or regenerate new hard tissues such as bones, cartilage, and/or dental tissues are disclosed. The formulation comprising two proteins is administered to enhance biological activities of a hard tissue g... | 12/29/2009 |
| 7622438 | Protein formulation for promoting hard tissue formation Formulations and methods to promote biological processes to form or regenerate new hard tissues such as bones, cartilage, and/or dental tissues are disclosed. The formulation enhances biological activities of a hard tissue growth and differentiation factor character... | 11/24/2009 |
| 7579020 | Controlled release arginine α-ketoglutarate An oral formulation of arginine α-ketoglutarate is disclosed which formulation is comprised of arginine α-ketoglutarate and one or more excipient materials. A wide range of different controlled release formulations will be apparent to those skilled in the art upon... | 08/25/2009 |
| 7563594 | Cytolethal distending toxins and detection of bacteria using the same as a target The present inventors succeeded in cloning the CDT genes of C. coli and C. fetus, which were previously unknown, and in determining their sequences. In addition, the inventors also developed specific primers and primers common to the two species by com... | 07/21/2009 |
| 7026126 | Method for detecting megsin protein and use thereof The present invention provides a method for evaluating renal functions by measuring megsin protein in a biological specimen. Moreover, the present invention provides immunological assay reagents, as well as kits useful for the measurement of megsin protein in the bi... | 04/11/2006 |
| 6919326 | Carbonyl-stress improving agent and peritoneal dialysate Carbonyl compounds generated and accumulated in the peritoneal dialysate can be inactivated or eliminated by a carbonyl compound-trapping agent such as aminoguanidine. Carbonyl compounds generated during sterilization and storage of the peritoneal dialysate can be e... | 07/19/2005 |
| 7516789 | Hydrocarbon recovery facilitated by in situ combustion utilizing horizontal well pairs The invention provides hydrocarbon recovery processes that may be utilized in heavy oil reservoirs. Horizontal hydrocarbon production wells may be provided below horizontal oxidizing gas injection wells, with distant combustion gas production wells offset from the i... | 04/14/2009 |
| 7498021 | Dental products comprising bone growth enhancing peptide Dental products such as toothpastes, mouthwash and dental floss are disclosed which products are enhanced by having dissolved, dispersed or coated thereon a compound which promoted bone growth. Preferred compounds are peptide sequences comprising 10 to 50 amino acid... | 03/03/2009 |
| 7490603 | Method of use of monomeric insulin as a means for improving the reproducibility of inhaled insulin The need for the delivery of insulin by injection can be reduced or eliminated by delivering an aerosolized monomeric insulin formulation. Repeatability of dosing and more particularly the repeatability of the blood concentration versus time profile is improved rela... | 02/17/2009 |
