Bizarre Patents
Neuroimaging as a Marketing Tool
Neuroimaging as a means for validating whether a stimulus such as advertisement, communication, or product evokes a certain mental response such as emotion, preference, or memory, or to predict the consequences of the stimulus on later behavior such as consumption or purchasing.
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| Number | Title | Issue Date |
| 8097425 | Multiplex protein fractionation The invention provides methods, compositions, and kits for multiplex fractionation of proteins in a sample. Protein-binding molecules, such as small epitope antibodies or small epitope aptamers, are used for multiplex fractionation of proteins in a protein containin... | 01/17/2012 |
| 8071322 | Method for identifying differentially expressed proteins The invention provides a method of identifying an antigen that is present in different amounts in two different samples. In general, the methods involve generating a first and second distinguishably labeled population of antibodies that reactive to the two samples, ... | 12/06/2011 |
| 8062867 | Fusion partner for production of monoclonal rabbit antibodies The invention provides a rabbit-derived immortal B-lymphocyte capable of fusion with a rabbit splenocyte to produce a hybrid cell that produces an antibody. The immortal B-lymphocyte does not detectably express endogenous immunoglobulin heavy chain and may contain, ... | 11/22/2011 |
| 8039795 | Ion sources for improved ionization Improved apparatuses and methods are provided for ionizing samples and analyzing the samples with mass spectrometry. ... | 10/18/2011 |
| 8036835 | Probe design methods and microarrays for comparative genomic hybridization and location analysis Methods and systems for identifying and selecting nucleic acid probes for detecting a target with a nucleic acid probe array or comparative genome hybridization microarray, comprising selecting a plurality of potential target sequences, generating a plurality of can... | 10/11/2011 |
| 8034917 | Primer-directed chromosome painting An oligonucleotide composition is provided. The subject composition comprises: a mixture of at least 10 of sets of oligonucleotides, wherein each of the sets of oligonucleotides comprises at least 100 different oligonucleotides of the following formula: X1 | 10/11/2011 |
| 8032346 | System and method for high-content oncology assay The present invention provides an apparatus, system, method and computer program and computer program product for analyzing cellular samples. One embodiment of the apparatus and method provides a multiparameter assay that provides information with respect to cell pr... | 10/04/2011 |
| 8030095 | Gel microdrop composition and method of using the same A gel microdrop composition is provided. In certain embodiments, the gel microdrop composition contains a polymer matrix, an effector particle that releases an effector molecule into the polymer matrix, a first reporter particle that emits a first optically detectab... | 10/04/2011 |
| 8025891 | Porin B (PorB) as a therapeutic target for prevention and treatment of infection by The present invention features peptides of a PorB polypeptide, which PorB peptides are useful in production of antibodies that bind the full-length PorB polypeptide and as a therapeutic agent. In specific embodiments the invention features a composition comprising o... | 09/27/2011 |
| 8021844 | Enzymatic labeling of RNA Methods are described in which a sample containing RNA is contacted with an enzyme having an RNA ligation activity in the presence of a labeled substrate to provide labeled RNA. Methods of performing an array analysis of a labeled RNA sample are also described. ... | 09/20/2011 |
| 8017328 | Genome partitioning using a nicking endonuclease A method for partitioning a genome is provided. In certain embodiments, the method comprises: a) nicking a region of the genome using a sequence-specific nicking endonuclease to produce a nicked double-stranded genomic region; b) hybridizing the nicked double-strand... | 09/13/2011 |
| 8017313 | Human G protein-coupled receptor and modulators thereof for the treatment of cardiovascular disorders The present invention relates to methods of identifying whether a candidate compound is a modulator of a G protein-coupled receptor (GPCR). In some embodiments, the GPCR is mammalian, preferably human. In some embodiments, the GPCR is expressed endogenously by cardi... | 09/13/2011 |
| 8012765 | Method for mixing a film of fluid A method and apparatus is provided for mixing a film of fluid, particularly a film of chemical, biochemical, or biological fluids undergoing a reaction. The apparatus comprises a means for nucleating a bubble using a discrete heat source, such as a resistor, and mov... | 09/06/2011 |
| 7448375 | Method of treating diabetes mellitus in a patient Dosages of inhaled insulin are controlled within a narrow range by controlling the total volume of air inhaled by a patient. By repeatedly delivering aerosolized insulin with the same total inhaled volume of air, the amount of insulin delivered to the patient each t... | 11/11/2008 |
| 7354721 | Highly sensitive proteomic analysis methods, and kits and systems for practicing the same Methods of determining whether a sample includes one or more analytes, particularly proteinaceous analytes, of interest are provided. In the subject methods, an array of binding agents, where each binding agent includes an epitope binding domain of an antibody, is c... | 04/08/2008 |
| 7199281 | Method of generating a transgenic livestock animal The present invention provides methods of producing transgenic livestock animals. The methods generally involve first introducing a nucleoprotein made up of nucleic acid and a recombinase into a totipotent or pluripotent cell to produce a recombinant totipotent or p... | 04/03/2007 |
| 7176280 | Isolated polypeptides and compositions from the venom of and methods of use The invention provides isolated polypeptides from the venom of the scorpion P. transvaalicus. The invention also provides novel scorpion antivenom compositions derived from such polypeptides, as well as methods for isolating the polypeptides and preparing sco... | 02/13/2007 |
| 6953585 | Soil amendment compositions Soil amendment compositions and methods for using the same are provided. The subject compositions are aqueous compositions consisting essentially of a carbon-skeleton energy component, a predisposing agent and a vitamin-cofactor component. The subject compositions f... | 10/11/2005 |
| 6855504 | In vivo high throughput toxicology screening method A high throughput toxicology screening method is provided. In the subject method, at least 10 different compound compositions are tested simultaneously. Each compound composition is tested by contacting it with a plurality, e.g. from about 10 to 1000, of non-mammali... | 02/15/2005 |
| 6831101 | Tricyclic rantes receptor ligands In various aspects, the invention provides compounds that bind to one or more RANTES receptors for the treatment of chemokine mediated disease states, such as compounds of formula (I): ... | 12/14/2004 |
| 6830744 | Compositions methods and systems for pulmonary delivery of recombinant human interferon alpha-2b Stable aqueous formulations which are free of products derived from human or animal origin and which maintain high biological activity and high chemical and physical stability of alpha-type interferon for an extended period of time. Methods of producing stable aeros... | 12/14/2004 |
| 6824988 | Method and compositions for use in diagnosing and characterizing chronic immune disease Methods are provided for diagnosing and/or characterizing chronic immune disease activity in a subject. In the subject methods, a sample is obtained from a subject suspected of having or known to have a chronic immune disease. The sample is then assayed for the pres... | 11/30/2004 |
| 6784283 | Peptide antibiotics N- and C-modified linear cationic peptides having antibiotic activity are disclosed, which peptides are particularly active against gram positive bacteria. ... | 08/31/2004 |
| 6755811 | Methods and devices for reducing the mineral content of a region of non-intimal vascular tissue Methods and devices for reducing the mineral content of a region of non-intimal vascular tissue are provided. In the subject methods, an isolated local environment that includes the region to be demineralized is produced. The pH of the local environment is then redu... | 06/29/2004 |
| 6712798 | Multilumen catheters and methods for their use Multilumen catheters are provided. The subject multilumen catheters include a proximal end and a distal end separated by a non-coaxial multilumen tube. The subject catheters are further characterized in that they include a multiport manifold at their proximal ends, ... | 03/30/2004 |
| 6706767 | Therapeutics for chemokine mediated diseases The invention provides therapeutic and biological uses of chemokine-receptor-binding compounds including uses in the treatment of disease states mediated by chemokines. The relevant chemokines may for example be monocyte chemoattractant protein-one (MCP-1) or interl... | 03/16/2004 |
| 6703498 | Water-soluble polymeric metal ion affinity compositions and methods for using the same Water-soluble metal ion affinity compounds and methods for using the same are provided. The subject compounds include an aspartate based metal chelating ligand bonded to a water-soluble polymeric substrate, where the ligand is complexed with a metal ion. ... | 03/09/2004 |
| 6693134 | Bicyclic aromatic chemokine receptor ligands The invention provides therapeutic and biological uses of chemokine-receptor-binding compounds (including chemokine receptor ligands such as chemokine receptor agonists or antagonists), such as naphthoic acid derivatives, including uses in the treatment o... | 02/17/2004 |
| 6686159 | Methods and compositions for modulating telomerase reverse transcriptase (TERT) expression Methods and compositions are provided for modulating, and generally upregulating, the expression of telomerase reverse transcriptase (TERT) by blocking repression of TERT transcription, e.g., by inhibiting binding of repressor factor to a Site C repressor... | 02/03/2004 |
| 6680305 | Physiologically acceptable aqueous solutions and methods for their use Physiologically acceptable aqueous solutions and methods for their use are provided. The subject solutions comprise: electrolytes; a dynamic buffering system and an oncotic agent; and do not comprise a conventional biological buffer. The subject solutions... | 01/20/2004 |
| 6664099 | Method for the preservation of viruses and mycoplasma A biologically-active material comprising a live virus or mycoplasma is preserved by a method of desiccation, without lyophilisation, in a matrix of glassy trehalose having a residual moisture content of not greater than 2%. The method comprises two vacuu... | 12/16/2003 |
| 6660905 | Mice comprising engrafted functional human hepatocytes Non-human mammalian hosts are provided, comprising functional human hepatocytes. Isolated human hepatocytes or fragments of human hepatic tissue are introduced into the xenogeneic host in conjunction with one or more agent that stimulates human hepatocyte... | 12/09/2003 |
| 6654963 | Outdoor jacket In one aspect, the invention provides a hood drawstring arrangement that may be adapted to allow a single adjustment to exert tension along the vertical sides of the front face opening of the hood, which will tend to vertically compress the hood, as well ... | 12/02/2003 |
| 6627393 | Solutions for use as plasma expanders and substitutes An artificial plasma-like substance having at least one water soluble polysaccharide oncotic agent selected from the group consisting of high molecular weight hydroxyethyl starch, low molecular weight hydroxyethyl starch, dextran 40 and dextran 70, which ... | 09/30/2003 |
| 6622732 | Methods and devices for reducing the mineral content of vascular calcified lesions Methods and devices are provided for at least reducing the mineral content of a vascular calcified lesion, i.e. a calcified lesion present on the vascular tissue of a host. In the subject methods, the local environment of the lesion is maintained at a sub... | 09/23/2003 |
| 6617113 | Methods of determining the presence of double stranded nucleic acids in a sample Methods for determining the presence of double stranded nucleic acids in a sample are provided. In the subject methods, nucleic acids present in a fluid sample are translocated through a nanopore, e.g. by application of an electric field to the fluid samp... | 09/09/2003 |
| 6613752 | Methods of in vivo gene transfer using a sleeping beauty transposon system Methods and compositions for introducing a nucleic acid into the genome of at least one cell of a multicellular organism are provided. In the subject methods, a Sleeping Beauty transposon that includes the nucleic acid is administered to the multicellular... | 09/02/2003 |
| 6604052 | Methods for use in three-dimensional structural determination Methods and compositions for determining the three dimensional structure of a particle are provided. In the subject methods, a plurality of images of the identically heavy atom labeled particles of interest is obtained. Each of the images in the plurality... | 08/05/2003 |
| 6602905 | N-acyl homoserine lactones for the treatment of cardiac tachyarrhythmias, ischaemic heart disease or congestive heart failure Compounds having anti-fibrotic effects are provided. Also provided is a method for treating disorders, diseases or conditions associated with pathological fibrotic states. The compounds useful in the present invention are homocysteine thiolactone and sele... | 08/05/2003 |
| 6589223 | Method and compositions for use in perfusion applications Methods and compositions for use in perfusion applications are provided. In the subject methods, a subject or derivative thereof, e.g. isolated organ or tissue, is infused, perfused and/or transfused with at least two fluid compositions. The first fluid c... | 07/08/2003 |
