Bizarre Patents
Crispy Chip Sandwich and Process of Producing a Sandwich Product
A food product comprising a multilayer cookie or snack having outer layers formed from a crispy type edible food product such as a potato chip or corn chip, etc. with an intermediate marshmallow layer being in contact with the inner surface of each crispy chip and one or more filler substances.
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| Number | Title | Issue Date |
| 8114853 | Methods of treating smooth muscle cell disorders The present invention provides methods of detecting cells showing smooth muscle differentiation. The present invention further provides methods of detecting tumor cells. The present invention further provides compositions and methods for treating smooth muscle cell ... | 02/14/2012 |
| 8114843 | Photoreactive regulator of protein function and methods of use thereof The present invention provides a synthetic regulator of protein function, which regulator is a light-sensitive regulator. The present invention further provides a light-regulated polypeptide that includes a subject synthetic regulator. Also provided are cells and me... | 02/14/2012 |
| 8114645 | Methods for increasing isoprenoid and isoprenoid precursor production by modulating fatty acid levels The present invention provides methods of increasing production of an isoprenoid or an isoprenoid precursor in a host cell, the methods generally involving modulating the level of activity of a fatty acid biosynthetic pathway enzyme in the host cell and/or culturing... | 02/14/2012 |
| 8108149 | Method and device for diagnosing and treating insulin-like growth factor deficiency disorders The present invention provides standard deviation score (SDS) calculators, which SDS calculators are useful for transforming insulin-like growth factor-1 (IGF-1) concentrations to IGF-1 standard deviation scores. In one embodiment, IGF-1 blood levels are calculated ... | 01/31/2012 |
| 8106152 | Antimicrobial composition The present invention relates to novel antimicrobial composition comprising a peptide which can be obtained from the milk protein casein or chemically synthesised or produced by recombinant DNA technology and a divalent cation. ... | 01/31/2012 |
| 8101399 | Artemisinic epoxide and methods for producing same The present invention provides artemisinic epoxide, and methods of synthesizing artemisinic epoxide in a genetically modified host cell. The present invention further provides methods for producing artemisinin. The present invention further provides variant enzymes ... | 01/24/2012 |
| 8097438 | Nucleic acids encoding modified cytochrome P450 enzymes and methods of use thereof The present invention provides nucleic acids comprising nucleotide sequences encoding modified cytochrome P450 enzymes; as well as recombinant vectors and host cells comprising the nucleic acids. The present invention further provides methods of producing a function... | 01/17/2012 |
| 8093353 | Agents for treatment of HCV and methods of use An amphipathic helix at the approximate N-terminus of Hepatitis C virus (HCV) nonstructural proteins mediates the association of these proteins with cytoplasmic membranes in infected cells. This association is essential for replication. Thus, assessing the ability o... | 01/10/2012 |
| 8076496 | Chemoselective ligation The present invention features a chemoselective ligation reaction that can be carried out under physiological conditions. In general, the invention involves condensation of a specifically engineered phosphine, which can provide for formation of an amide bond between... | 12/13/2011 |
| 8071074 | Preventing airway mucus production by administration of EGF-R antagonists Hypersecretion of mucus in the lungs is inhibited by the administration of an epidermal growth factor receptor (EGF-R) antagonist. The EGF-R antagonist may be in the form of a small organic molecule, an antibody, or portion of an antibody that binds to and blocks th... | 12/06/2011 |
| 8048844 | Preventing airway mucus production by administration of EGF-R antagonists Hypersecretion of mucus in the lungs is inhibited by the administration of an epidermal growth factor receptor (EGF-R) antagonist. The EGF-R antagonist may be in the form of a small organic molecule, an antibody, or portion of an antibody that binds to and blocks th... | 11/01/2011 |
| 8034565 | Gene expression markers for breast cancer prognosis The present invention provides gene sets the expression of which is important in the diagnosis and/or prognosis of breast cancer. ... | 10/11/2011 |
| 8034350 | Methylated tat polypeptides and methods of use thereof The present invention provides isolated methylated Tat peptides; and compositions comprising the peptides. The present invention further provides isolated antibodies specific for a Lys-51-methylated Tat polypeptide. Also provided are methods of identifying agents th... | 10/11/2011 |
| 8029995 | Gene expression markers for colorectal cancer prognosis A method of predicting clinical outcome in a subject diagnosed with colorectal cancer comprising determining evidence of the expression of one or more predictive RNA transcripts or their expression products in a biological sample of cancer cells obtained from the su... | 10/04/2011 |
| 8026060 | Gene expression markers for colorectal cancer prognosis A method of predicting clinical outcome in a subject diagnosed with colorectal cancer comprising determining evidence of the expression of one or more predictive RNA transcripts or their expression products in a biological sample of cancer cells obtained from the su... | 09/27/2011 |
| 7974705 | Multiplexed multi-electrode neurostimulation devices Implantable stimulation devices are provided. Aspects of the devices include a multiplexed multi-electrode component configured for neural stimulation. The multiplexed multi-electrode component includes two or more individually addressable satellite electrode struct... | 07/05/2011 |
| 7969161 | Optimal drive frequency selection in electrical tomography Electrical tomography drive frequency selection systems and methods are disclosed. One aspect of the present invention pertains to a system for optimally selecting a drive frequency of an electrical tomography which comprises a sensor electrode stably associated wit... | 06/28/2011 |
| 7935056 | Intravascularly implantable integrated circuits Techniques for controlling one or more modular circuits (“satellites”) that are intended for placement in a subject's body. The one or more satellites are controlled by sending signals over a bus that includes first and second conduction paths. Also coupled to t... | 05/03/2011 |
| 7771363 | Coronary sinus sensing device The present invention provides a new mechanical sensor approach to maneuvering catheters and other cardiac devices into blood outlets, with particular application to maneuvering cardiac devices into the coronary sinus and beyond. Additionally, the inventive sensing ... | 08/10/2010 |
| 7767654 | Methods for treating bleeding disorders using sulfated polysaccharides Methods for treating bleeding disorders using non-anticoagulant sulfated polysaccharides (NASPs) as procoagulants are disclosed. NASPs can be administered as single agents, or in combination with one another, or with other medications (such as factors VII, VIII and ... | 08/03/2010 |
| 7762138 | Pressure sensor circuits Implantable pressure sensors and methods for making and using the same are provided. A feature of embodiments of the subject pressure sensors is that they are low-drift sensors. The subject sensors find use in a variety of applications. ... | 07/27/2010 |
| 7736882 | Host cells for production of isoprenoid compounds Methods for synthesizing isopentenyl pyrophosphate are provided. A first method comprises introducing into a host microorganism a plurality of heterologous nucleic acid sequences, each coding for a different enzyme in the mevalonate pathway for producing isopentenyl... | 06/15/2010 |
| 7682613 | Anti-leukocyte recruitment therapy for the treatment of seizures and epilepsy Methods are provided for the prevention and treatment of seizures and epilepsy. It is shown herein that leukocyte recruitment plays a key role in the pathogenesis of epilepsy. Treatment with an agent that inhibits leukocyte recruitment has therapeutic and preventati... | 03/23/2010 |
| 7640060 | Implantable satellite effectors Techniques for controlling one or more modular circuits (“satellites”) that are intended for placement in a subject's body. The one or more satellites are controlled by sending signals over a bus that includes first and second conduction paths. Also coupled to t... | 12/29/2009 |
| 7638640 | Purifications of pomegranate ellagitannins and their uses thereof Compositions of purified and biologically active ellagitannins are provided by separation from pomegranate husk using a method of extraction and purification using a solid polymeric adsorbent and the uses of the said compounds. ... | 12/29/2009 |
| 7638278 | Markers of DNA copy number alteration for improved prognostication in prostate cancer The invention describes DNA copy number alterations (CNAs), identifiable by technologies such as array-based comparative genomic hybridization (array CGH) or fluorescence in situ hybridization (FISH), that define distinct genetic subtypes of prostate cancer, and are... | 12/29/2009 |
| 7622255 | Methods of identifying and isolating stem cells and cancer stem cells Methods and compositions are provided for the identification of stem cells and cancer stem cells. β-catenin is also identified as a target for the development of therapeutic moieties against hematopoietic tumors, i.e. leukemia and lymphoma cells, which may include ... | 11/24/2009 |
| 7316360 | Pore structures for reduced pressure aerosolization A nozzle comprising a thin, flexible substantially planar polymeric film having a plurality of pores with structures allowing for generation of an aerosol at reduced extrusion pressure is disclosed. The pores can comprise at least two sections, or steps, in which th... | 01/08/2008 |
| 7297836 | Methods of detecting neurological disorders The present invention provides methods of detecting an amyloid peptide-related neurological disorder in an individual; and methods for staging an amyloid peptide-related neurological disorder in an individual. The methods involve detecting a level of a calcium-respo... | 11/20/2007 |
| 7297532 | Surface based translation system Translationally competent ribosomes are bound to a solid substrate through a specific attachment site. A spatial array of such immobilized ribosomes may be produced on a planar substrate, microbeads, on fiber optics. One or more components of the ribosome complex ar... | 11/20/2007 |
| 7279300 | Protozoan rhomboid proteins Protozoan Rhomboid Proteins. The invention relates to the identification of protozoan Rhomboid proteins that are involved in the invasive processes of protozoan pathogens, such as P falciparum. Modulation of these Rhomboid proteins may this be useful in treat... | 10/09/2007 |
| 7238369 | Cationic liposome delivery of taxanes to angiogenic blood vessels Angiogenic endothelial cells are selectively targeted with lipid/DNA complexes or cationic liposomes containing a substance which affects the targeted cells by inhibiting or promoting their growth. A site of angiogenesis can be precisely located by administering cat... | 07/03/2007 |
| 7208478 | Immunostimulatory polynucleotide/immunomodulatory molecule conjugates Immunostimulatory polynucleotide-immunomodulatory molecule conjugate compositions are disclosed. These compositions include a polynucleotide that is linked to an immunomodulatory molecule, which molecule comprises an antigen and may further comprise immunomodulators... | 04/24/2007 |
| 7097835 | Immunoselective targeting agents and methods of use thereof The present invention provides immunoselective targeting agents that bind to transporters that are transiently accessible on the surface of neuronal cells, and that deliver compounds selectively to such cells. The invention provides methods of selectively killing, a... | 08/29/2006 |
| 7081561 | Gene-targeted animal model of apolipoprotein E4 domain interaction and uses thereof The invention provides gene-targeted non-human animals comprising a genetically modified apoE gene encodes a recombinant apoE polypeptide displaying domain interaction. The invention further provides cells isolated from the gene-targeted animals, which cells produce... | 07/25/2006 |
| 6652136 | Method of simultaneous mixing of samples A flow-through microcentrifuge comprising a container in which a sample is placed, and a power source capable of rotating the container around an axis. High speed rotation causes the components of the sample to separate according to their respective densi... | 11/25/2003 |
| 6242175 | Methods and means relating to retrotransposon and retroviral integration Ku(Ku70 and Ku80) of yeast and mammalian cells and other components of the Ku-associated DNA repair pathway are involved in retrotransposon and retroviral integration into cellular nucleic acids. Agents which inhibit activity of the pathway are useful for... | 06/05/2001 |
