Bizarre Patents
Ballistic resistant body covering
A ballistic resistant body covering for protecting the torso, groin and neck area from ballistic missiles.
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 5821251 | Nitrogen heterocycles This invention concerns a compounds of generic formula: ##STR1## or a pharmaceutically acceptable salt thereof, where the dotted lines represent optional bonds with the nitrogen ring optional bonds being between one adjacent pair on ring atoms, R | 10/13/1998 |
| 5807864 | 2-thioxo-tetrahydropyrimidin-4-one derivatives This invention relates to the use of 2-thioxotetrahydropyrimidin-4-one derivatives to increase HDL cholesterol concentration and as therapeutic compositions for treating atherosclerotic conditions such as dyslipoproteinemias and coronary heart disease. Th... | 09/15/1998 |
| 5756501 | Saturated and unsaturated pyridazino4,5-B! indolizines useful as antidementia agents This invention relates to novel compounds which bind to central cholinergic muscarinic M1 receptors and may be useful for treatment of diseases attributed to cholinergic insufficiency such as presenile dementia, senile dementia of the Alzheimer's type, Pa... | 05/26/1998 |
| 5753676 | 6-aryl-(methyl - or methylidone)-quinoline derivatives as voltage-gated potassium channel blockers This invention concerns a compound of generic formula: ##STR1## or a pharmaceutically acceptable salt thereof, where the dotted lines represent optional bonds, R3 is an optionally substituted C6 -C10 aryl or heteroaryl ... | 05/19/1998 |
| 5723468 | 6-membered ring fused imidazoles as muscarinic agents The compound of the formula: ##STR1## where R1 is H, alkyl, perhaloalkyl, arylalkyl, alkenyl or alkynyl; R2 is H when R4 is other than H, and, when R4 is H, R2 is ##STR2## in which R | 03/03/1998 |
| 5723464 | Piperazine derivatives Compounds are disclosed which have the general formula A: ##STR1## where Ra and Rb are each hydrogen or methyl and Rc is hydrogen, halo or C1-4 alkyl optionally in the form of a pharmaceutically acceptable ... | 03/03/1998 |
| 5712270 | 2-arylamidothiazole derivatives with CNS activity This invention relates to methods of treating neurological illnesses related to acetylcholine deficiency in the CNS including memory loss attending senility, Parkinson's disease, Down's syndrome or senile pugilistica by administering a therapeutically eff... | 01/27/1998 |
| 5693642 | Piperazine derivatives as 5-HT1A ligands Piperazine derivatives of formula (I) and their salts are 5-HT1A binding agents and may be used, for example, as anxiolytics. In the formula, R, R2 and R4 are hydrogen or lower alkyl, R1 is mono- or bicyclic ary... | 12/02/1997 |
| 5688821 | Unsaturated fatty acyl derivatives of 2-aminothiazoleacetic acid and their salts as inhibitors of phospholipase A2 derived from human sources This invention relates to compounds of the formula ##STR1## where R1 and R2 are both hydrogen or R1 and R2 form a bond; m=1 and n=3 and p=6, or m=3, 5 or 7 and n=1 and p=6, or m=4 and n=2 and p=6 or 8, and the E... | 11/18/1997 |
| 5681839 | Nitrogen heterocycles This invention concerns a compound of generic formula ##STR1## or a pharmaceutically acceptable salt thereof, where the dotted lines represent optional bonds, R3 is an optionally substituted C6 -C10 aryl or heteroaryl ... | 10/28/1997 |
| 5677342 | Phenoxy acetic acids as aldose reductase inhibitors and antihyperglycemic agents This invention relates to 4-formyl-2-(naphthalenylmethyl)phenoxyacetic acids and pharmaceutically acceptable salts thereof according to formula I below, pharmaceutical compositions thereof, a method of treating hyperglycemia due to non-insulin dependent d... | 10/14/1997 |
| 5629323 | Amide derivatives as 5-HT1A ligands Amide Derivatives of formula (I) wherein R1 is a mono or bicyclic heteroaryl radical, R2 is cycloalkyl, R3 and R4 each represent hydrogen or lower alkyl, and R5 is a group of formula (A) or (B) or (C)... | 05/13/1997 |
| 5627177 | Piperazine derivatives Piperazine derivatives of formula (I) and their pharmaceutically acceptable salts are 5-HT1A binding agents and may be used, for example, as anxiolytics. In the formula, A is an optionally substituted alkylene chain, Z is a specified bicyclic n... | 05/06/1997 |
| 5622963 | Innovative technique for immunosuppression involving administration of rapamycin loaded formed blood elements This invention relates to a technique for treating a mammal with rapamycin which comprises removal of blood from the patient, treatment of the formed blood elements with rapamycin which binds rapidly and reversibly with erythrocytes, and returning the tre... | 04/22/1997 |
| 5622951 | Piperazine derivatives as 5-HT antagonists Piperazine derivatives of formula (I) and their pharmaceutically acceptable salts are 5-HT1A binding agents and may be used, for example, as anxiolytics. In the formula, R and R3 are hydrogen or lower alkyl or R3 is spiroc... | 04/22/1997 |
| 5610295 | 4-amino-2-(hetero)aryl-butanamides useful as 5-HT1A -antagonists Amide Derivatives of formula (I): R5 NR4 (CR2)2 CHR3 CONR1 R2 and their pharmaceutically acceptable salts are 5-HT1A binding agents and may be used, for example, as anxiolytics. ... | 03/11/1997 |
| 5610197 | Benzyl and naphthalenylmethyl thiophenones and cyclopentenones as antihyperglycemic agents This invention relates to benzyl and naphthalenylmethyl thiophenones and cyclopentenones, some of which are novel, which have oral antihyperglycemic activity in diabetic mice, a genetic animal model of non-insulin dependent diabetes mellitus. These compou... | 03/11/1997 |
| 5604238 | Z-benzylidene-tetrahydroquinolines and analogues thereof This invention concerns compounds having the Z-configuration of formula: ##STR1## or salts thereof, wherein R represents an optionally substituted aryl or heteroaryl radical, R1, R2 and R3 each independently represent... | 02/18/1997 |
| 5597834 | Z-benzylidene-tetrahydroquinolines and analogues thereof This invention concerns compounds having the Z-configuration of formula: ##STR1## or salts thereof, wherein R represents an optionally substituted aryl or heteroaryl radical, R1, R2 and R3 each independently represent... | 01/28/1997 |
| 5543418 | Innovative technique for immunosuppresion involving administration of rapamycin loaded formed blood elements This invention relates to a technique for treating a mammal with rapamycin which comprises removal of blood from the patient, treatment of the formed blood elements with rapamycin which binds rapidly and reversibly with erythrocytes, and returning the tre... | 08/06/1996 |
| 5541205 | Aryl-n-hydroxyureas as inhbitors of 5-lipoxygenase and anti-arteriosclerotic agents This invention relates to compounds which inhibit lipoxygenase in the metabolism of arachidonic acid and thus inhibits formation of leukotrienes which are implicated in inflammatory processes and bronchoconstriction and inhibits the oxidation of LDL which... | 07/30/1996 |
| 5541179 | Tropon-2-one piperazine carboxamides as serotonergic agents This invention relates to compounds useful as anxiolytic agents having the formula: ##STR1## where A is ##STR2## wherein X is O or S; R1 is selected from H, --CN, --OR3, --NO2, --NR3 R4... | 07/30/1996 |
| 5532256 | New azolidinediones and thiadiazolidinediones as antihyperglycemic agents This invention relates to novel compounds which have demonstrated oral antihyperglycemic activity in diabetic ob/ob and db/db mice, animal models on non-insulin dependent diabetes mellitus (NIDDM ot Type II diabetes). These compounds have the formula: ... | 07/02/1996 |
| 5527804 | 4-carbamoyloxy-piperidine-1-carboxylic acid esters: inhibitors or cholesterol absorption Compounds which inhibit the enzyme cholesterol ester hydrolase (CEH) thus inhibit the formation of esterified cholesterol. Esterified cholesterol is absorbed through the intestine and inhibition of the enzyme therefore results in inhibition of cholesterol... | 06/18/1996 |
| 5519037 | N-cyanoamidine derivatives as anti-influenza agents Antiinfluenza A activity was found in compounds of the formula: ##STR1## wherein X is ##STR2## where one of R1 and R2 is H and the other is phenylamino and Z is --SCH3 or a pharmaceutically acceptable salt thereo... | 05/21/1996 |
| 5510360 | Azolidinediones as antihypergylcemic agents This invention relates to novel compounds which have demonstrated oral antihyperglycemic activity in diabetic ob/ob and db/db mice, animal models on non-insulin dependent diabetes mellitus (NIDDM ot Type II diabetes). These compounds have the formula: ... | 04/23/1996 |
| 5504097 | N-hydroxyureas as 5-lipoxygenase inhibitors and inhibitors of oxidative modification of low density lipoprotein This invention relates to compounds having 5-lipoxygenase inhibiting properties and inhibition of oxidative modification of low density lipoprotein which have the formula: ##STR1## wherein: R1 and R3 are independently hydrogen, ... | 04/02/1996 |
| 5500442 | Cyclobut-3-ene-1,2-dione derivatives as smooth muscle relaxants The present invention relates to novel cyclobut-3-ene-1,2-dione-3-yl substituted benzopyrans, indanes and tetrahydronaphthalenones having smooth muscle relaxant activity, pharmaceutical compositions containing them, and to their use in the treatment of di... | 03/19/1996 |
| 5482945 | Innovative technique for immunosuppression involving administration of rapamycin loaded formed blood elements This invention relates to a technique for treating a mammal with rapamycin which comprises removal of blood from the patient, treatment of the formed blood elements with rapamycin which binds rapidly and reversibly with erythrocytes, and returning the tre... | 01/09/1996 |
| 5482942 | (3,4-dioxocyclobuten-1-yl)chromene, indene, and dihydronaphthalenone derivatives as smooth muscle relaxants This invention relates to novel 4-(3,4-dioxocyclobuten-1-yl)chromenes and dihydronaphthalenones and 3-(3,4-dioxocyclobuten-1-yl)indenes and salts thereof having smooth muscle relaxing activity, to their use in the treatment of hypertension as well as for ... | 01/09/1996 |
| 5480896 | Aralkyl-1,2,4-oxadiazolidine-3,5-diones as antihyperglycemic agents This invention relates to novel compounds having antihyperglycemic properties of the formula: ##STR1## where A is ##STR2## wherein: n is 1 or 2; R1 and R3 are independently hydrogen, C1 -C8 alkyl, ... | 01/02/1996 |
| 5475012 | N-cyanoamidine derivatives as anti-influenza agents Antiinfluenza A activity was found in compounds of the formula: ##STR1## wherein: X is 2-phenylethyl, 2-furanylmethyl, or ##STR2## where one of R1 and R2 is H and the other is phenylamino; Z is --SCH3 when X is ... | 12/12/1995 |
| 5468760 | Aralkyl-N-hydroxyureas as inhibitors of 5-lipoxygenase and oxidation of low density lipoprotein This invention relates to compounds compounds useful in treating diseases mediated by one or more leukotrienes or oxidative modification of low density lipoprotein such as inflammation, bronchoconstriction or atherosclerosis. The compounds of this inventi... | 11/21/1995 |
| 5459154 | N-hydroxyureas as 5-lipoxygenase inhibitors and inhibitors of oxidative modification of low density lipoprotein This invention relates to compounds having 5-lipoxygenase inhibiting properties and inhibition of oxidative modification of low density lipoprotein which have the formula: ##STR1## wherein: R1 and R3 are independently hydrogen, ... | 10/17/1995 |
| 5459151 | N-acyl substituted phenyl piperidines as bronchodilators and antiinflammatory agents This invention relates to novel PDE-IV inhibitors having the formula: ##STR1## where: R1 =H, C1 -C6 alkyl; R2 =C3 -C7 alkyl, C3 -C7 cycloalkyl or C4 -C... | 10/17/1995 |
| 5444086 | Naphthalenylmethyl thiophenones as antihyperglycemic agents This invention relates to benzyl and naphthalenylmethyl thiophenones and cyclopentenones, some of which are novel, which have oral antihyperglycemic activity in diabetic mice, a genetic animal model of non-insulin dependent diabetes mellitus. These compou... | 08/22/1995 |
| 5438064 | Derivatives of 4-anilinoquinoline-3-carboxamide as analgesic agents Derivatives of 4-anilinoquinoline having the formula: ##STR1## where X is O or H2 and Z is 1-substituted-4-piperidinylamino or diloweralkylaminoloweralkyl inhibit binding of tritiated bradykinin to guinea pig ileum and inhibit bradykinin-i... | 08/01/1995 |
| 5430033 | Piperazine derivatives Piperazine derivatives of formula I ##STR1## and their pharmaceutically acceptable acid addition salts are 5-HT1A binding agents, particularly 5-HT1A antagonists and may be used, for example, as anxiolytics. In the formula R is ... | 07/04/1995 |
| 5428048 | Aryl-N-hydroxyureas as inhibitors of 5-lipoxygenase and anto-arteriosclerotic agents This invention relates to compounds which inhibit lipoxygenase in the metabolism of arachidonic acid and thus inhibits formation of leukotrienes which are implicated in inflammatory processes and bronchoconstriction and inhibits the oxidation of LDL which... | 06/27/1995 |
| 5399588 | Naphthalenylmethyl cycloalkenone acetic acids and analogs thereof useful as aldose reductase inhibitors The compounds of this invention which have the formula: ##STR1## wherein: R1 and R2 are independently hydrogen, C1 -C8 alkyl, halogen, C1 -C8 alkoxy, or trifluoromethyl; R3 is --... | 03/21/1995 |
