Did You Know...
...Chester Carlson was a patent agent who tired of having to make multiple copies of patent applications using the only duplication method available at the time: carbon paper. In 1959 he came up with a new copying system and took it to IBM for evaluation. The "experts" at IBM determined potential sales to be only 5,000 units because people wouldn't want to use a bulky machine when they had carbon paper. Carlson's invention was the xerography process, the company founded on the system is Xerox.
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| Number | Title | Issue Date |
| 8178125 | Oral formulations of glycyl-2-methylprolyl-glutamate Oral formulations of G-2MePE including microemulsions, coarse emulsions, liquid crystals, tablets and encapsulated forms of G-2MePE have improved bioavailability than conventional aqueous formulations. In particular, microparticles, nanoparticles and microemulsions ... | 05/15/2012 |
| 8158348 | Apparatus and method for preparative scale purification of nucleic acids Apparatus and methods are described for pharmaceutical grade manufacture extrachromosomal nucleic acids from cell lysates using flotation to separate and eliminate undesired insoluble cellular debris including chromosomal DNA from the lysates. A gas is introduced to... | 04/17/2012 |
| 8146893 | Apparatus and method for generating and tracing vortices Apparatus and methods for generating and tracing vortices include an actuator that is moved through a fluid is such a fashion as to produce a difference in pressure between two faces, so that the fluid is drawn from an area of higher pressure into an area of lower p... | 04/03/2012 |
| 8088630 | Nanoparticle and microparticle based detection of cellular products Embodiments of the present invention relate to devices and methods for detecting cellular products using detection particles having product-specific detection reagents and having a characteristic spectral feature. In particular, devices and methods are provided for ... | 01/03/2012 |
| 8081068 | Centre high mount stop lamp with constituent seatbelt disengagement indicator Embodiments of the invention detect and visually indicate to onlookers when a motor vehicle driver's and/or passenger's seatbelt is not engaged. An embodiment is comprised of control electronics, wiring, and an on-board Centre High Mount Stop Lamp (“CHMSL”) moun... | 12/20/2011 |
| 8075902 | Diagnosis and treatment of cancer related to human dormancy New devices and methods for diagnosis and compositions and methods for treatment of cancers use combinations of antimicrobial agents and agents that can reverse dormancy and hibernation pathways. We unexpectedly found that surprisingly low doses of anti-hibernation ... | 12/13/2011 |
| 8067425 | Neuroprotective bicyclic compounds and methods for their use Embodiments of this invention provide novel cyclic compounds structurally related to diketopiperazines and methods for their therapeutic use. Such compounds are neuroprotective and have utility as therapeutic agents for treatment of diseases, injuries and other cond... | 11/29/2011 |
| 8031782 | Systems and methods for compression, transmission and decompression of video codecs Embodiments of this invention include computer-implemented mathematical methods to develop software and/or hardware implementations that use wavelet transforms (WT) to pre-process video frames that can then be compressed using a variety of codecs to produce compress... | 10/04/2011 |
| 8013170 | Substituted pyrrolo[1,2-d][1,4]-diazonines and treatment of brain damage Embodiments of this invention provide novel peptidomimetics that contain a macrocycle, an embodiment of which is 2S,9′S,12′S)-2-{[(1′,4′-Diaza-2′-oxobicyclo[7.3.0]dodecyl)-12′-carbonyl]amino}-1,5-pentanedioic acid trifluoroacetate. Such compounds are neu... | 09/06/2011 |
| 7963957 | Visual indicator for electrosurgical instrument fields A device to visually indicate the presence of electric fields in electrosurgical apparatus, without the necessity of wiring or an electrical connection to the apparatus, to visually annunciate when an electrosurgical instrument is active is disclosed. This is to ale... | 06/21/2011 |
| 7918779 | Therapeutic methods using electromagnetic radiation This invention provides methods for treating a variety of disorders using localized electromagnetic radiation directed at excitable tissues, including nerves, muscles and blood vessels. By controlling the wavelength, the wavelength bandpass, pulse duration, intensit... | 04/05/2011 |
| 7887839 | Oral formulations of glycyl-2-methylprolyl-glutamate Oral formulations of G-2MePE including microemulsions, coarse emulsions, liquid crystals, tablets and encapsulated forms of G-2MePE have improved bioavailability than conventional aqueous formulations. In particular, microparticles, nanoparticles and microemulsions ... | 02/15/2011 |
| 7878965 | Therapeutic methods using electromagnetic radiation This invention provides methods for treating a variety of disorders using localized electromagnetic radiation directed at excitable tissues, including nerves, muscles and blood vessels. By controlling the wavelength, the wavelength bandpass, pulse duration, intensit... | 02/01/2011 |
| 7863304 | Analogs of glycyl-prolyl-glutamate Embodiments of this invention include novel analogs of Glycyl-Prolyl-Glutamate (GPE) and compositions containing such analogs of GPE. Of these, certain analogs have modified proline residues. Other embodiments of this invention include uses of analogs of GPE to prot... | 01/04/2011 |
| 7807822 | Methods for purifying nucleic acids Methods are provided for producing highly purified compositions of nucleic acids by using a highly streamlined and readily automated process. The methods use static mixers for lysing cells and precipitating debris, followed by centrifugation and ion exchange chromat... | 10/05/2010 |
| 7776876 | Cyclic G-2Allylproline in treatment of Parkinson's disease Embodiments of this invention provide methods for thereapeutic use of cyclic G-2-Allyl Proline to treat disorders of dopaminergic neurons, including Parkinson's disease. Cyclic G-2Allyl P is neuroprotective and has utility as a therapeutic agent for treatment of dis... | 08/17/2010 |
| 7771945 | Apparatus and method for preparative scale purification of nucleic acids Apparatus and methods are described for pharmaceutical grade manufacture extrachromosomal nucleic acids from cell lysates using flotation to separate and eliminate undesired insoluble cellular debris including chromosomal DNA from the lysates. A gas is introduced to... | 08/10/2010 |
| 7767786 | Neural regeneration peptides and methods for their use in treatment of neural injury or degeneration The invention discloses a family of neuronal migration-inducing, proliferation-promoting and neurite outgrowth promoting factors, termed NRP compounds, and provides compositions and methods for the use of NRP compounds in the treatment of brain injury and neurodegen... | 08/03/2010 |
| 7758869 | Immunogenic compositions The invention relates to immunogenic compositions and to methods for immunizing animals using the same. The immunogenic composition comprises a lipid formulation most usually in solid form, and at least one immunogenic component. A preferred immunogenic component is... | 07/20/2010 |
| 7720306 | Systems and methods for displaying changes in biological responses to therapy Systems and methods of this invention display data using pixels with information indicated by color and intensity changes, particularly used for monitoring of physiological variables in real time. For certain methods, physiological data can be acquired by sensors, a... | 05/18/2010 |
| 7714020 | Treatment of non-convulsive seizures in brain injury using G-2-methyl-prolyl glutamate Aspects of this invention include the use of G-2MePE to treat patients with brain injury characterized by non-convulsive seizures. G-2MePE is useful in treating brain injuries caused by traumatic brain injury, stroke, hypoxia/ischemia and toxic injury. ... | 05/11/2010 |
| 7650236 | Means, methods, and apparatus to reduce the possibility of a motor vehicle entering a freeway ramp in the wrong direction of travel—towards oncoming traffic A system used to reduce the possibly of a vehicle entering a freeway ramp in the wrong direction of travel, towards oncoming traffic, is disclosed. The preferred system is comprised of equipment used in conjunction with orbiting satellite transceivers with receivers... | 01/19/2010 |
| 7648704 | Diagnosis and treatment of human dormancy syndrome New methods for diagnosis of human dormancy syndrome are provided. Human dormancy syndrome is characterized by elevated serum ratio of rT3/fT3 compared to a population of normal subjects from which subjects suffering from fibromyalgia, chronic fatigue, obesity, deme... | 01/19/2010 |
| 7605177 | Effects of glycyl-2 methyl prolyl glutamate on neurodegeneration This invention provides analogs and peptidomimetics of glycyl-L-prolyl-L-glutamic acid (GPE). In particular, this invention relates to GPE analogs and peptidomimetics that are anti-apoptotic, anti-necrotic and have neuroprotective effects. These agents are useful in... | 10/20/2009 |
| 7598093 | Nanoparticle and microparticle based detection of cellular products Embodiments of the present invention relate to devices and methods for detecting cellular products using detection particles having product-specific detection reagents and having a characteristic spectral feature. In particular, devices and methods are provided for ... | 10/06/2009 |
| 7563862 | Neural regeneration peptides and methods for their use in treatment of brain damage The invention discloses a family of peptides termed NRP compounds or NRPs that can promote neuronal migration, neurite outgrowth, neuronal proliferation, neural differentiation and/or neuronal survival, and provides compositions and methods for the use of NRPs in th... | 07/21/2009 |
| 7535401 | Activation of remote control transmitter functions by external inputs The ability to operate remote control transmitter functions from external sensors, in conjunction with internal or external controls, to provide condition dependant automatic control of devices such as digital video recorders and the like are presented. The system e... | 05/19/2009 |
| 7485298 | Diagnosis and treatment of human dormancy-related sequellae New methods for diagnosis and treatment of human dormancy syndrome-related sequellae are provided. Human dormancy syndrome (HDS) is characterized by elevated serum ratio of rT3/fT3 compared to a population of normal subjects. HDS includes fibromyalgia, chronic fatig... | 02/03/2009 |
| 7485630 | Neuroprotective macrocyclic compounds and methods for their use Embodiments of this invention provide novel peptidomimetics that contain a macrocycle. Such compounds are neuroprotective and have utility as therapeutic agents for treatment of diseases, injuries and other conditions characterised by neuronal degeneration and/or de... | 02/03/2009 |
| 7370021 | Medical applications of adaptive learning systems using gene expression data A neural network module is provided. It comprises an input layer comprising one or more input nodes configured to receive gene expression data. It also has a rule base layer comprising one or more rule nodes and an output layer comprising one or more output nodes co... | 05/06/2008 |
| 7317840 | Methods for real-time software video/audio compression, transmission, decompression and display The invention presents new methods of compression, transmission, and decompression of video signals providing increased speed and image quality. Methods based on wavelet transformation with decimation and time stamping can provide one-pass encoding of signals in whi... | 01/08/2008 |
| 7304029 | Neuroprotective effect of growth hormone The invention relates to neuroprotection and to medicaments for use therein. Neuroprotection is induced by activation of neural growth hormone receptors, primarily using medicaments comprising growth hormone, growth hormone analogs or ligands which are functionally ... | 12/04/2007 |
| 7288257 | Diagnosis and treatment of human dormancy syndrome New methods for diagnosis of human dormancy syndrome are provided. Human dormancy syndrome is characterized by elevated serum ratio of rT3/fT3 compared to a population of normal subjects from which subjects suffering from fibromyalgia, chronic fatigue, obesity, deme... | 10/30/2007 |
| 7282342 | Methods for detecting weakly immunogenic analytes GPE antibodies recognize GPE with high specificity. When used in a radioimmunoassay, they reliably measure the concentration of GPE. They may be used to extend the half-life of GPE both in vivo and in vitro, and in methods of purifying the GPE receptor. Two methods ... | 10/16/2007 |
