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| Number | Title | Issue Date |
| 8048170 | Method for treating morbid obesity A method for treating morbid obesity in a body of a mammal having a gastrointestinal tract extending through a stomach and a pyloric sphincter and a wall forming the stomach and pyloric sphincter. At least one implant is formed in the wall in the vicinity of the pyl... | 11/01/2011 |
| 7670688 | Erosion-resistant components for plasma process chambers An erosion-resistant article for use as a component in plasma process chamber. The erosion-resistant article comprises a support and an oxide coating comprising yttrium, which is disposed over the support. The support and the oxide coating preferably have material c... | 03/02/2010 |
| 7625552 | Bioactive polymers for imparting bioactive character to hydrophobic medical article surfaces According to an aspect of the present invention, bioactive polymers are provided which have (a) a hydrophilic bioactive portion and (b) at least one hydrophobic polymer group that is linked to the hydrophilic bioactive portion by a covalent linkage that contains a c... | 12/01/2009 |
| 7622530 | Drug delivery compositions and medical devices containing block copolymer A composition for delivery of a therapeutic agent is provided. The composition comprises: (a) a biocompatible block copolymer comprising one or more elastomeric blocks and one or more thermoplastic blocks and (b) a therapeutic agent, wherein the block copolymer is l... | 11/24/2009 |
| 7613634 | Method and system for performing electronic retailing A bar code scanning and information retrieval system is integrated into a consumer electronic device that has an otherwise main and different function or purpose. Location determining technology, or a user interface through which location-specific information is pro... | 11/03/2009 |
| 7594928 | Bioabsorbable stents with reinforced filaments According to an aspect of the present invention, a stent is provided, which contains at least one filament that has a longitudinal axis and comprises a bioabsorbable polymeric material. Polymer molecules within the bioabsorbable polymeric material are provided with ... | 09/29/2009 |
| 7566297 | Electroactive polymer based artificial sphincters and artificial muscle patches Provided are artificial muscle patches, which are adapted to be implanted adjacent a patient's heart, and artificial sphincter cuffs, which are adapted to be implanted around a body lumen, such as the urethra, the anal canal, or the lower esophagus. The devices of t... | 07/28/2009 |
| 7491188 | Reinforced and drug-eluting balloon catheters and methods for making same The present invention generally relates to the field of intravascular medical devices, and more specifically to the field of balloon catheters and other similar diagnostic or therapeutic catheters within the body for treatment and diagnosis of diseases. In particula... | 02/17/2009 |
| 7491185 | External counterpulsation device using electroactive polymer actuators The present invention provides an exterior counterpulsation (ECP) system that includes a garment for being worn on the exterior of a patient's body. The garment includes electroactive polymer (EAP) actuators connected thereto. In one embodiment, the EAP actuators ar... | 02/17/2009 |
| 7491234 | Medical devices for delivery of therapeutic agents The present invention is generally directed to medical devices, and more specifically to medical devices that are at least partially insertable or implantable into the body of a patient. The medical devices generally comprise (a) a therapeutic agent, more typically,... | 02/17/2009 |
| 7488794 | High yield S-nitrosylation process A method for producing a S-nitrosylated species is provided. The method comprises: (a) providing a deoxygenated, alkaline aqueous solution comprising a thiol and a nitrite-bearing species; (b) acidifying the solution by adding acid to the solution while concurrently... | 02/10/2009 |
| 7410497 | Stimulation of cell growth at implant surfaces The present invention is directed to medical devices that contain at least one tissue contacting surface that is configured to undergo a variation in surface charge in response to a time-dependent signal. Such a variation in surface charge is provided, for example, ... | 08/12/2008 |
| 7407668 | Medical articles having enzymatic surfaces for localized therapy An enzymatically active medical article is provided, which comprises a medical article and an enzyme disposed at or near a surface of the medical article such that the medical article is provided with an enzymatically active surface. The enzyme is selected, for exam... | 08/05/2008 |
| 7390525 | Processes for producing polymer coatings for release of therapeutic agent A method for furnishing a therapeutic-agent-containing medical device is provided. The method comprises: (a) providing a reactive layer comprising a cross-linking agent on a medical device surface; and (b) subsequently applying a polymer-containing layer, which comp... | 06/24/2008 |
| 7381418 | Implantable or insertable medical devices containing radiation-crosslinked polymer for controlled delivery of a therapeutic agent An implantable or insertable medical device which comprises (a) a therapeutic agent and (b) a polymeric release region that controls the release of the therapeutic agent upon administration to a patient. The polymeric release region comprises a radiation-crosslinked... | 06/03/2008 |
| 7371223 | Electroactive polymer actuated heart-lung bypass pumps A pump apparatus, which comprises: (a) a tubular portion comprising an electroactive polymer actuator that expands and contracts an inner volume of the tubular portion based upon received control signals; and (b) a control unit electrically coupled to the electroact... | 05/13/2008 |
| 7364585 | Medical devices comprising drug-loaded capsules for localized drug delivery A medical device comprising a plurality of capsules, and a method of administering therapeutic agent to a patient using the same. The capsules further comprise a therapeutic agent and a multilayer polyelectrolyte shell. The medical device is adapted to apply a press... | 04/29/2008 |
| 7357940 | Implantable or insertable medical devices containing graft copolymer for controlled delivery of therapeutic agents Implantable or insertable medical devices are described. The medical devices comprise (a) a therapeutic agent and (b) a polymeric release region that controls the release of the therapeutic agent upon administration to a patient. The polymer release region comprises... | 04/15/2008 |
| 7338509 | Electroactive polymer actuated sheath for implantable or insertable medical device A medical device delivery sheath, which comprises an active member that volumetrically expands and contracts upon application of an appropriate electrical potential. The active member further comprises an electroactive polymer, for example, polypyrrole. Also describ... | 03/04/2008 |
| 7335375 | Controlling resorption of bioresorbable medical implant material The resorption of a medical implant can be controlled with the use of particles embedded in a resorbable bulk material forming the implant or portion thereof. The implant can be removed from a body of a mammal by natural biological mechanisms after use. The resorpti... | 02/26/2008 |
| 7335155 | Unitary formulation delivery device An apparatus for delivering a formulation into a body in integer amounts includes a cannula with an insertion end for insertion into the body. The cannula includes a channel such as a tube to store the formulation. A rod is inserte... | 02/26/2008 |
| 7261686 | Universal, programmable guide catheter A guide catheter apparatus that comprises the following: (a) a guide catheter portion that includes a plurality of electroactive polymer actuators disposed along its axial length and (b) a control unit coupled to the actuators and sending control signals to the actu... | 08/28/2007 |
| 7241455 | Implantable or insertable medical devices containing radiation-crosslinked polymer for controlled delivery of a therapeutic agent An implantable or insertable medical device which comprises (a) a therapeutic agent and (b) a polymeric release region that controls the release of the therapeutic agent upon administration to a patient. The polymeric release region comprises a radiation-crosslinked... | 07/10/2007 |
| 7226622 | Chemoablation of tissue using biodegradable, solid salt dosage forms Novel methods for the chemical ablation of tissue (e.g. prostatic tissue) are described. These methods include the steps of: (a) providing one or more solid salt dosage form comprising 50-100% w/w salt; and (b) inserting one or more of such solid salt dosage forms i... | 06/05/2007 |
| 7199427 | DMOS device with a programmable threshold voltage A DMOS device is provided which is equipped with a floating gate having a first and second electrode in close proximity thereto. The floating gate is separated from one of the first and second electrodes by a thin layer of dielectric material whose dimensions and co... | 04/03/2007 |
| 7187119 | Methods and structures for reducing lateral diffusion through cooperative barrier layers A covered substrate is described, which comprises: (a) a flexible substrate layer; and (b) a plurality of cooperative barrier layers disposed on the substrate layer. The plurality of cooperative barrier layers further comprise one or more planarizing layers and one ... | 03/06/2007 |
| 7137966 | Immobilizing objects in the body Stabilizing an object in the body of a patient involves the injection of a lower critical solution temperature (LCST) material or other flowable material into the body of the patient so that the material contacts the object. The LCST material or other flowable mater... | 11/21/2006 |
| 7135189 | Compositions and techniques for localized therapy A therapeutic medical article is provided which comprises a medical article, a precursor compound and an activator compound. The medical article is adapted, upon administration to a patient, to release the precursor compound and the activator compound such that the ... | 11/14/2006 |
| 7128707 | Electroactive polymer based artificial sphincters and artificial muscle patches Provided are artificial muscle patches, which are adapted to be implanted adjacent a patient's heart, and artificial sphincter cuffs, which are adapted to be implanted around a body lumen, such as the urethra, the anal canal, or the lower esophagus. The devices of t... | 10/31/2006 |
| 7105175 | Implantable or insertable medical devices for controlled delivery of a therapeutic agent The present invention is directed to novel implantable or insertable medical devices that provide controlled release of a therapeutic agent. According to an embodiment of the present invention, a therapeutic-agent-releasing medical device is provided, which comprise... | 09/12/2006 |
| 7097615 | Robotic endoscope with wireless interface An endoscope apparatus and method of operating the same. The endoscope apparatus comprises an endoscope portion and a control and display unit. The endoscope portion preferably comprises: (i) a sensor disposed at a distal end of the endoscope portion and providing e... | 08/29/2006 |
| 7083697 | Porous spun polymeric structures and method of making same A non-woven polymeric matrix for separating leukocytes from a blood sample includes a non-woven three dimensional matrix formed from polymeric fibers having a predetermined pore volume fraction including a defined channel configuration, a predetermined pore size in ... | 08/01/2006 |
| 7077808 | Ultrasonic imaging catheter An ultrasonic imaging catheter apparatus and a method of using the same to scan the inner wall of a body lumen. The ultrasonic imaging catheter apparatus comprises: (a) a flexible elongate element adapted for insertion into a body lumen, the elongate element having ... | 07/18/2006 |
| 7063671 | Electronically activated capture device A novel capture device apparatus comprising: (a) a capture device portion, at least a part of which is adaptable for insertion into a patient and (b) a control unit. The capture device portion comprises one or more apertures and one or more electroactive polymer act... | 06/20/2006 |
| 7060056 | Biocompatible pharmaceutical articles Many conventional pharmaceutical articles contain seemingly inert components that come into contact with a pharmaceutically active material during use, which contact substantially reduces the pharmaceutical effectiveness of the pharmaceutically active material. The ... | 06/13/2006 |
| 7045142 | Sustained release of superoxide dismutase mimics from implantable of insertable medical devices An implantable or insertable medical device is provided which comprises (a) a superoxide dismutase mimic and (b) a polymeric release region. Upon administration to a patient, the polymeric release region controls the release of the superoxide dismutase mimic, which ... | 05/16/2006 |
| 7041047 | Method and apparatus for the delivery of brachytherapy A brachytherapy device includes a radiation source and a multi-cannula delivery system for implantation of the radiation source into a body tissue site. The radiation source may be, for example, a substantially straight round wire, a substantially straight flat wire... | 05/09/2006 |
| 7012363 | OLEDs having increased external electroluminescence quantum efficiencies OLED devices are disclosed having increased external electroluminescence quantum efficiencies, i.e., increased “out-coupling” efficiencies. OLED devices that have increased out-coupling efficiencies and that are also protected from environmental elements such as... | 03/14/2006 |
| 6998648 | Protected organic electronic device structures incorporating pressure sensitive adhesive and desiccant Organic electronic device structures are provided, which comprise: (a) a first portion comprising a substrate and an organic electronic device region (e.g., an OLED region) disposed over the substrate; (b) a second portion comprising a cover and a getter region; and... | 02/14/2006 |
| 6997870 | Universal, programmable guide catheter A guide catheter apparatus that comprises the following: (a) a guide catheter portion that includes a plurality of electroactive polymer actuators disposed along its axial length and (b) a control unit coupled to the actuators and sending control signals to the actu... | 02/14/2006 |