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Felix Hoffmann, a German chemist, was searching for something to relieve his father's arthritis. In doing so, he "rediscovered" acetylsalicylic acid and in 1900, patented a stable process for developing it. Hence, we have aspirin.
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| Number | Title | Issue Date |
| 5874108 | Salt coated tablet The invention provides a coated tablet, a coating composition and a method of film coating. The coating is particularly useful for pharmaceutical tablets. The coating composition is composed of an aqueous solution of film forming inorganic salts which may... | 02/23/1999 |
| 5837286 | Taste masking for unplatable formulations This invention provides a taste masking composition composed of clove oil and either supportive flavor components or calcium carbonate. This taste masking composition has been found to be particularly useful to mask unpalatable medicinals in formulations ... | 11/17/1998 |
| 5656293 | Delivery system for enhanced onset and increased potency The invention discloses a swallow tablet which is capable of disintegrating within less than about fifteen minutes and providing fast delivery of therapeutic drugs. The delivery system is composed of between 0.250 and 1.0 Gm of an alkali metal or alkaline... | 08/12/1997 |
| 5462198 | Modular bottle dispenser The present invention is directed to a modular bottle dispenser apparatus used for dispensing bottles. Each dispenser includes a receiver opening, a dispenser opening, a continuous guide channel which restricts the side to side and up and down motion of a... | 10/31/1995 |
| 5449824 | Recovery of organic acid salts from impure process streams by addition of bases This invention provides an improved method for recovering an organic acid as a salt from various process streams by addition of a crystallizing base to a concentrated solution of neutralized organic acid. The addition of such a base causes crystallization... | 09/12/1995 |
| 5424075 | Delivery system for enhanced onset and increased potency The invention discloses a swallow tablet which is capable of disintegrating within less than about fifteen minutes and providing fast delivery of therapeutic drugs. The delivery system is composed of between 0.250 and 1.0 Gm of an alkali metal or alkaline... | 06/13/1995 |
| 5352825 | Recovery of organic acid salts from impure process streams by addition of bases This invention provides an improved method for recovering an organic acid as a salt from various process streams by addition of a crystallizing base to a concentrated solution of neutralized organic acid. The addition of such a base causes crystallization... | 10/04/1994 |
| 5348745 | Aqueous granulation solution and a method of tablet granulation The invention discloses an aqueous granulating solution containing sodium, potassium or mixed sodium potassium salt of an edible organic acid selected from the group consisting of citric, malic, tartaric and fumaric acid and optionally containing sodium o... | 09/20/1994 |
| 5266713 | Aryl alkenoic acid derivatives as leukotriene antagonists Aryl alkenoic acid derivatives, and physiologically acceptable salts thereof, are provided which are potent leukotriene antagonists and may be used for the treatment of circulatory diseases and preferably for respiratory diseases such as asthma. The deriv... | 11/30/1993 |
| 5073377 | Method of preparing oral dosage forms with a granulating composition The invention involves a granulating composition composed of an aqueous solution of magnesium sulfate heptahydrate and sodium hexametaphosphate. This composition can be used to prepare granules of ingredients for inclusion in any formulation for which rap... | 12/17/1991 |
| 5043176 | Synergistic antimicrobial compositions The invention discloses an antimicrobial composition composed of an antimicrobial polypeptide and a hypothiocyanate component. Synergistic activity is seen when the composition is applied at between about 30 and 40 degrees Centigrade at a pH between about... | 08/27/1991 |
| 4965072 | Granulating composition and method The invention involves a granulating composition composed of an aqueous solution of magnesium sulfate heptahydrate and sodium hexametaphosphate. This composition can be used to prepare granules of ingredients for inclusion in any formulation for which rap... | 10/23/1990 |
| 4783331 | Method for solubilization of aspartame in effervescent aqueous systems; and composition A method and composition for providing aspartame as a sweetener in effervescent calcium ion-generating systems is provided. The method includes a step for providing a selected surfactant in association with the aspartame sweetener, to provide for aqueous ... | 11/08/1988 |
| 4755472 | Stable composition for the determination of peroxidatively active substances A stable test device for the determination of a peroxidatively active substance comprising a carrier containing 1,4-diisopropylbenzene dihydroperoxide and a benzidine indicator in a molar ratio of from 0.9 to 3.0. The composition can be incorporated in a ... | 07/05/1988 |
| 4683209 | Viability test device A viability test device wherein the viability of a test composition for the determination of an analyte of interest can be determined by simply wetting the device with ordinary water. The viability device can be prepared in three formats: a control or cal... | 07/28/1987 |
| 4670218 | Ion test means having a porous carrier matrix A test means for determining the presence of an ion in an aqueous test sample is disclosed, as well as a test device incorporating the test means, a method for preparing it and a method for using it. The test means is composed of a porous carrier matrix i... | 06/02/1987 |
| 4650768 | Stable chloride test device A stable test device capable of manufacture by automated methods for the determination of chloride in an aqueous fluid sample. The test device operates by controlled diffusion of the aqueous sample into a porous matrix. The matrix is incorporated with sod... | 03/17/1987 |
| 4649121 | Viability test device A viability test device wherein the viability of a test composition for the determination of an analyte of interest can be determined by simply wetting the device with ordinary water. The viability device can be prepared in three formats: a control or cal... | 03/10/1987 |
| 4649123 | Ion test means having a hydrophilic carrier matrix A test means for determining the presence of an ion in an aqueous test sample, a method for preparing it and a method for using it. The test means comprises a hydrophilic carrier matrix incorporated with finely divided globules of a hydrophobic vehicle. T... | 03/10/1987 |
| 4621049 | Enzymatic high range glucose test A test composition comprising glucose oxidase, a peroxidatively active component, a chromogenic indicator system capable of providing a detectable response and a borate buffer capable of providing an initial pH above about pH 7 is particularly useful for ... | 11/04/1986 |
| 4608335 | Enzymatic urea assay A composition, device and method useful as an enzymatic urea assay based on the use of urea amidolyase comprising urea amidolyase, pyruvate kinase, pyruvate oxidase, mono and divalent cations, phosphoenolpyruvate, thyamine pyrophosphate, ATP, bicarbonate,... | 08/26/1986 |
| 4604356 | Purification of flavin adenine dinucleotide synthetase The invention provides a flavin adenine dinucleotide (FAD) synthetase preparation with a specific activity at 25° C. greater than at least 75 nanomoles per minute per milligram of protein in the preparation and usually greater than at least 150 nanomoles... | 08/05/1986 |
| 4587220 | Ascorbate interference-resistant composition, device and method for the determination of peroxidatively active substances A composition, test means (and device) and method for determining peroxidatively active substances in a test sample are disclosed. The composition, test means (and device) and method are rendered resistant to the adverse affects of ascorbate which may be ... | 05/06/1986 |
| 4556640 | Stabilized test composition, device and method for the determination of peroxidatively active substances A test composition, device and method for determining a perioxidatively active substance in a test sample, as well as a method for preparing and using the device, are disclosed. The composition comprises an organic hydroperoxide, a benzidine indicator cap... | 12/03/1985 |
