...that Charles Goodyear performed some of his experiments on rubber while in debtor's prison? He was there so often he referred to it as his "hotel". Chronically in debt because of poor business sense and ill health, Goodyear depended on the generosity of friends and family. Even after he unlocked the secret to vulcanizing rubber, he was unable to improve his financial situation. When he died, his estate was $200,000 in debt.
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| Number | Title | Issue Date |
| 7091489 | Positron emission tomography wrist detector A method of serially transferring annihilation information in a compact positron emission tomography (PET) scanner includes generating a time signal representing a time-of-occurrence of an annihilation event, generating an address signal representing a channel detec... | 08/15/2006 |
| 7076959 | Enhanced magnetocaloric effect material A magnetocaloric effect heterostructure having a core layer of a magnetostructural material with a giant magnetocaloric effect having a magnetic transition temperature equal to or greater than 150 K, and a constricting material layer coated on at least one surface o... | 07/18/2006 |
| 7075030 | Shielded beam delivery apparatus and method An apparatus includes a plasma generator aligned with a beam generator for producing a plasma to shield an energized beam. An electrode is coaxially aligned with the plasma generator and followed in turn by a vortex generator coaxially aligned with the electrode. A ... | 07/11/2006 |
| 7074386 | Pressure induced swelling in microporous materials A method for capturing specified materials which includes contacting a microporous material with a hydrostatic fluid having at least one specified material carried therein, under pressure which structurally distorts the lattice sufficiently to permit entry of the at... | 07/11/2006 |
| 7029921 | Apparatus for rapid measurement of aerosol bulk chemical composition An apparatus for continuous on-line measurement of chemical composition of aerosol particles with a fast time resolution is provided. The apparatus includes an enhanced particle size magnifier for producing activated aerosol particles and an enhanced collection devi... | 04/18/2006 |
| 7005525 | Recyclable catalysts methods of making and using the same Organometallic complexes are provided, which include a catalyst containing a transition metal, a ligand and a component having the formula GArF. ArF is an aromatic ring system selected from phenyl, naphthalenyl, anthracenyl, fluorenyl, or inden... | 02/28/2006 |
| 6995260 | Carboranylporphyrins and uses thereof The present invention is directed to low toxicity boronated compounds and methods for their use in the treatment, visualization, and diagnosis of tumors. More specifically, the present invention is directed to low toxicity carborane-containing 5, 10, 15, 20-tetraphe... | 02/07/2006 |
| 6989443 | Carboranylporphyrins and uses thereof The present invention is directed to low toxicity boronated compounds and methods for their use in the treatment, visualization, and diagnosis of tumors. More specifically, the present invention is directed to low toxicity carborane-containing 5, 10, 15, 20-tetraphe... | 01/24/2006 |
| 6974893 | Isoform of castor oleate hydroxylase The present invention relates to oleate hydroxylase genes, proteins, and methods of their use. The present invention also relates to methods of using the oleate hydroxylase genes and proteins, including in their expression in transgenic organisms and in the producti... | 12/13/2005 |
| 6951640 | Use of novel metalloporphyrins as imageable tumor-targeting agents for radiation therapy The present invention covers halogenated derivatives of boronated phorphyrins containing multiple carborane cages having the formula which selectively accumulate in neoplastic tissue within the irradiation volume and t... | 10/04/2005 |
| 6939876 | Prevention of addiction in pain management The present invention provides a composition for treating pain. The composition includes a pharmaceutically acceptable analgesic and a GABAergic agent, such as gamma vinyl GABA, effective in reducing or eliminating the addictive liability of the analgesic. The inven... | 09/06/2005 |
| 6921733 | Liquid phase low temperature method for production of methanol from synthesis gas and catalyst formulations therefor The invention provides a homogenous catalyst for the production of methanol from purified synthesis gas at low temperature and low pressure which includes a transition metal capable of forming transition metal complexes with coordinating ligands and an alkoxide, the... | 07/26/2005 |
| 6906099 | Treatment of addiction and addiction-related behavior using a composition of topiramate The present invention relates to the use of a composition that increases central nervous system GABA levels in a mammal, for the treatment of addiction to drugs of abuse and modification of behavior associated with addiction to drugs of abuse in said mammal. ... | 06/14/2005 |
| 6835303 | Method for reducing the sulfur content of a sulfur-containing hydrocarbon stream The sulfur content of a liquid hydrocarbon stream is reduced under mild conditions by contracting a sulfur-containing liquid hydrocarbon stream with transition metal particles containing the transition metal in a zero oxidation state under conditions sufficient to p... | 12/28/2004 |
| 6828349 | Treatment of addiction and addiction-related behavior The present invention provides a highly efficient method for treating substance addiction and for changing addiction-related behavior of a mammal suffering from substance addiction. The method includes administering to a mammal an effective amount of gamma vinylGABA... | 12/07/2004 |
| 6819113 | Precision grid survey apparatus and method for the mapping of hidden ferromagnetic structures The present invention is for a precision grid surveyor having a stationary unit and a roving unit. The stationary unit has a light source unit that emits a light beam and a rotator to project the light beam toward detectors on a roving unit. The roving unit moves ov... | 11/16/2004 |
| 6803203 | DNA-PK assay The present invention provides a method for detecting DNA-activated protein kinase (DNA-PK) activity in a biological sample. The method includes contacting a biological sample with a detectably-labeled phosphate donor and a synthetic peptide substrate defined by the... | 10/12/2004 |
| 6794339 | Synthesis of YBa2CU3O7 using sub-atmospheric processing The present invention is a method of forming thick films of crystalline YBa2Cu3O7 that includes forming a precursor film comprising barium fluoride (BaF2), yttrium (Y) and copper (Cu). The precursor film is heat-treated at... | 09/21/2004 |
| 6789022 | Method for assaying clustered DNA damages Disclosed is a method for detecting and quantifying clustered damages in DNA. In this method, a first aliquot of the DNA to be tested for clustered damages with one or more lesion-specific cleaving reagents under conditions appropriate for cleavage of the DNA to pro... | 09/07/2004 |
| 6759403 | Metalloporphyrins and their uses as radiosensitizers for radiation therapy The present invention covers radiosensitizers containing as an active ingredient halogenated derivatives of boronated porphyrins containing multiple carborane cages having the structure which selectively accumulate in ne... | 07/06/2004 |
| 6737234 | Structure of adenovirus bound to cellular receptor car Disclosed is a mutant adenovirus which has a genome comprising one or more mutations in sequences which encode the fiber protein knob domain wherein the mutation causes the encoded viral particle to have significantly weakened binding affinity for CARD1 relative to ... | 05/18/2004 |
| 6737531 | Catalysts for hydrogenation and hydrosilylation, methods of making and using the same A compound is provided including an organometallic complex represented by the formula I: [CpM(CO)2(NHC)Lk]+A− I wherein M is an atom of molybdenum or tangsten, Cp is substi... | 05/18/2004 |
| 6713497 | Use of vitamin B6 to mitigate visual field defects associated with the use of GABAergic drugs in mammals The invention provides a method for treating visual field defects in a mammal in need thereof by administering an effective amount of vitamin B6 to the mammal. ... | 03/30/2004 |
| 6686186 | Mutant fatty acid desaturase The present invention relates to a method for producing mutants of a fatty acid desaturase having a substantially increased activity towards fatty acid substrates with chains containing fewer than 18 carbons relative to an unmutagenized precursor desatura... | 02/03/2004 |
| 6670301 | Carbon monoxide tolerant electrocatalyst with low platinum loading and a process for its preparation An electrocatalyst is provided for use in a fuel cell that has low platinum loading and a high tolerance to carbon monoxide poisoning. The fuel cell anode includes an electrocatalyst that has a conductive support material, ruthenium nanoparticles reduced ... | 12/30/2003 |
| 6613213 | Method for producing electrodes using microscale or nanoscale materials obtained from hydrogendriven metallurgical reactions A method is provided for producing electrodes using microscale and nanoscale metal materials formed from hydrogen driven metallurgical processes; such a the HD (hydriding, dehydriding) process, the HDDR (hydriding, dehydriding, disproportionation, and rec... | 09/02/2003 |
| 6613923 | Catalytic ionic hydrogenation of ketones using tungsten or molybdenum catalysts with increased lifetimes The present invention is a process for the catalytic hydrogenation of ketones and aldehydes to alcohols at low temperatures and pressures using organometallic molybdenum and tungsten complexes and the catalyst used in the process. The reactants include a ... | 09/02/2003 |
| 6611379 | Beam splitter and method for generating equal optical path length beams The present invention is a beam splitter for splitting an incident beam into first and second beams so that the first and second beams have a fixed separation and are parallel upon exiting. The beam splitter includes a first prism, a second prism, and a f... | 08/26/2003 |
| 6608677 | Mini-lidar sensor for the remote stand-off sensing of chemical/biological substances and method for sensing same A method and apparatus for remote, stand-off, and high efficiency spectroscopic detection of biological and chemical substances. The apparatus including an optical beam transmitter which transmits a beam having an axis of transmission to a target, the bea... | 08/19/2003 |
| 6596423 | Method for low temperature catalytic production of hydrogen The invention provides a process for the catalytic production of a hydrogen feed by exposing a hydrogen feed to a catalyst which promotes a base-catalyzed water-gas-shift reaction in a liquid phase. The hydrogen feed can be provided by any process known i... | 07/22/2003 |
| 6593367 | Treatment of addiction and addiction-related behavior The present invention provides a method for changing addiction-related behavior of a mammal suffering from addiction to a combination of abused drugs. The method includes administering to the mammal an effective amount of gamma vinylGABA (GVG) or a pharma... | 07/15/2003 |
| 6576843 | Power superconducting power transmission cable The present invention is for a compact superconducting power transmission cable operating at distribution level voltages. The superconducting cable is a conductor with a number of tapes assembled into a subconductor. These conductors are then mounted co-p... | 06/10/2003 |
| 6566517 | Metalloporphyrins and their uses as imageable tumor-targeting agents for radiation therapy The present invention covers halogenated derivatives of boronated porphyrins containing multiple carborane cages having the formula ##STR1## which selectively accumulate in neoplastic tissue within the irradiation volume and thus can be used in cancer the... | 05/20/2003 |
| 6558868 | Method of fabricating a high aspect ratio microstructure The present invention is for a method of fabricating a high aspect ratio, freestanding microstructure. The fabrication method modifies the exposure process for SU-8, an negative-acting, ultraviolet-sensitive photoresist used for microfabrication whereby a... | 05/06/2003 |
| 6541520 | Treatment of addiction and addiction-related behavior The present invention provides a highly efficient method for treating substance addiction and for changing addiction-related behavior of a mammal suffering from substance addiction. The method includes administering to a mammal an effective amount of gamm... | 04/01/2003 |
| 6541514 | Process for the manufacture of 117Sn diethylenetriaminepentaacetic acids Novel methods are provided for the manufacture of 117m Sn(Sn4+) DTPA. The method allows the use of DTPA, a toxic chelating agent, in an approximately 1:1 ratio to 117m Sn(Sn4+) via either aqueous conditions, or ... | 04/01/2003 |
| 6537796 | Conversion of geothermal waste to commercial products including silica A process for the treatment of geothermal residue includes contacting the pigmented amorphous silica-containing component with a depigmenting reagent one or more times to depigment the silica and produce a mixture containing depigmented amorphous silica a... | 03/25/2003 |
| 6528948 | Plasma valve A plasma valve includes a confinement channel and primary anode and cathode disposed therein. An ignition cathode is disposed adjacent the primary cathode. Power supplies are joined to the cathodes and anode for rapidly igniting and maintaining a plasma i... | 03/04/2003 |
| 6524170 | Method of surface preparation of niobium The present invention is for a method of preparing a surface of niobium. The preparation method includes polishing, cleaning, baking and irradiating the niobium surface whereby the resulting niobium surface has a high quantum efficiency.... | 02/25/2003 |
| 6517810 | Therapeutic tin-117m compositions The invention provides a method for the palliation of bone pain due to cancer by the administration of a unique dosage of a tin-117m (Sn-117m) stannic chelate complex in a pharmaceutically acceptable composition. In addition, the invention provides a meth... | 02/11/2003 |