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| Number | Title | Issue Date |
| 8030330 | Benzothiophenes, formulations containing same, and methods This invention provides compounds of formula I and pharmaceutically acceptable salts and solvates thereof, characterized that the compound is in particulate form and having a specific size range. The present inventi... | 10/04/2011 |
| 7834194 | Cycloalkyl lactam derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 The present invention provides compounds of formula I that are useful as potent and selective inhibitors of 11-beta hydroxysteroid dehydrogenase 1. The present invention further provides a pharmaceutical composition which comprises a compound of Formula I, or a phar... | 11/16/2010 |
| 7045628 | Synthesis of 2-aryl-1-naphthol derivatives via a tandem palladium catalyzed arylation and dehydrogenation The present invention relates to a one-pot process for preparing a compound of formula I: I; by reacting a compound of formula II with a compound of formula III: in the presence of a suitable solvent, a suitable base, a palladium catalyst and a suitable ligand. ... | 05/16/2006 |
| 7012153 | Process for preparing benzoic acids An improved process for the preparation of 4[(2-piperidin-1-yl)ethoxy]benzoic acid derivatives, comprising reacting a haloalkyl amine of formula (III) with a compound of formula (IV) in the presence of a hydrated inorganic base in an appropriate solvent. ... | 03/14/2006 |
| 6921827 | Process for preparing 3-aryl-benzo{b} thiophenes The present invention relates to a process for preparing a compound of formula (I): which includes cyclodehydrating a compound of formula (II): in the presence of an acid activated clay or acid activated zeolite catalyst and in the presence of a suitable solvent | 07/26/2005 |
| 6812244 | Naphthyl compounds, intermediates, compositions, and methods of use The instant invention provides novel substituted naphthyl compounds, intermediates, compositions, pharmaceutical formulations, and methods of use. ... | 11/02/2004 |
| 6713494 | Amorphous benzothiophenes, methods of preparation and methods of use The instant invention provides an amorphous form of a compound of formula I Methods of preparing an amorphous form of a compound of formula I, pharmaceutical formulations containing same, and methods of using same are al... | 03/30/2004 |
| 6451817 | Alpha-substituted-1-benzyl-napthyls This invention relates to the fields of pharmaceutical and organic chemistry and provides novel 1-benzyl-naphthyls which are -substituted with ether, thioether, amino, hydrazino, cyano or halo that are useful for the treatment of the various medica... | 09/17/2002 |
| 6440958 | Acrylic and propionic acid compounds, intermediates, processes, compositions, and methods This invention is directed to a class of acrylic and propionic acid compounds and their use in the treatment of post-menopausal symptoms and restenosis. In other embodiments, the invention is directed to intermediates and to processes for the preparation ... | 08/27/2002 |
| 6350884 | Acrylic and propionic acid compounds, intermediates, processes, compositions, and method This invention is directed to a class of acrylic and propionic acid compounds and their use in the treatment of post-menopausal symptoms and restenosis. In other embodiments, the invention is directed to intermediates and to processes for the preparation ... | 02/26/2002 |