...that Robert Adler has the dubious distinction of being the Father of the Couch Potato? Back in 1955 Adler was employed by what was then Zenith Radio Corp., where he was charged to invent something that would allow viewers to turn down the TV volume without leaving their chairs. After a series of flops (such as a wired contraption that people tripped over), Adler hit on the idea of using sound waves. Thus the Remote Control was born...
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| Number | Title | Issue Date |
| 5466811 | Dioxolenylmethyl carbamates pro moieties for amine drugs This invention relates to a the use of new oxodioxolenylmethyl carbamates to produce bioreversible neutral prodrugs from primary and secondary amines.... | 11/14/1995 |
| 5464762 | Asymmetric bioreduction of 6-bromo-2-tetralone to (s)-6-bromo-2 tetraol by trichosporon capitatum Stereospecific (S)-6-bromo-2-tetraol is a key intermediate in the chemical synthesis of the chiral drug candidate, MK499, a ventricular arrythmias suppressant. The yeast strain Trichosporon capitatum (MY 1890) was employed for the bioconversion of 6-bromo... | 11/07/1995 |
| 5439914 | Spirocycles Compounds of the general structural formula: ##STR1## or a pharmaceutically acceptable salt, hydrate or crystal form thereof, wherein; X is O or CH2 R1 is H if R2 is not H or if R2 is H then R1 is ... | 08/08/1995 |
| 5428031 | Methods of treating cardiac arrhythmia Benzodiazepine analogs have been found to be useful in treating cardiac abnormalities.... | 06/27/1995 |
| 5426185 | Antiarrhythmic benzodiazepines Benzo-(1,5)-diazepine derivatives with an amide or urea function in the 3-position are useful in the treatment of arrhythmia. The compounds have structural formulae: ##STR1##... | 06/20/1995 |
| 5403846 | Spirocycles Compounds of the general formula: ##STR1## or a pharmaceutically acceptable salt, hydrate or crystal form enantiomer, diastereomer or mixtures thereof are Class III antiarrhythmic agents.... | 04/04/1995 |
| 5399587 | Biologically active compounds The present invention relates to novel potassium channel agonists which are useful in activating the calcium activated Maxi-K potassium channel in mammalian neuronal and smooth muscle tissue. The claimed compounds are of the general formula: ##STR1##... | 03/21/1995 |
| 5382587 | Spirocycles Spirocycles of the general structural formulae: ##STR1## wherein: X is O, CH2 or SOm ; R1 is AlkylSO2 NH--, AlkylO--, AlkylSO2 --, AlkylCONH--, or NO2 --; R2 is --H, --OAlkyl, or... | 01/17/1995 |
| 5378838 | Benzodiazepine cholecystokinin antagonists Benzodiazepine analogs of the formula: ##STR1## are disclosed which are antagonists of gastrin and cholecystokinin (CCK).... | 01/03/1995 |
| 5366738 | Controlled release drug dispersion delivery device A device for the controlled delivery of a beneficial agent as a gelatinous dispersion consisting of (i) a core which contains a beneficial agent, a polymer which forms gelatinous microscopic particles upon hydration and if desired an agent to modulate the... | 11/22/1994 |
| 5350584 | Spheronization process using charged resins The invention comprises a novel process for the spheronization of charged resins. Spherical multiparticlates are produced which range in size from 0.3 mm to 3 mm in diameter. The spherical particle product is microcrystalline-free. The process consists of... | 09/27/1994 |
| 5254345 | Poly(orthocarbonate acetal) bioerodible polymers Polymers obtained by condensing polyols with divinyl orthocarbonates are useful for making bioerodible polymers for sustained release of beneficial agents.... | 10/19/1993 |