Did You Know...
...that power steering was invented by independent inventor Francis W. Davis? As chief engineer in the 1920s of the truck division of the Pierce Arrow Motor Car Company, he saw how hard it was to steer heavy vehicles. So that he would be able to keep the profits from his future invention, Davis left his job, rented a small engineering shop in Waltham, Mass., and developed a hydraulic power steering system that led to power steering.
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| Number | Title | Issue Date |
| 7358278 | Cellular phosphorylation potential enhancing compositions preparation and use thereof A pharmaceutical composition comprising as an active phosphorylation potential enhancing substance a pharmaceutically-acceptable salt of an alpha-keto carboxylic acid thereof alone or in combination with nicatinamide and creatine and, its use and products containing... | 04/15/2008 |
| 5916224 | Tendon repair clip implant A tendon repair clip implant system for placement on the dorsal side of a cerated or torn tendon to allow active range of motion post tendon repair, comprises: first and second clips. Each clip comprises: (i) two serrated sections joined by integral connecting... | 06/29/1999 |
| 5864855 | Parallel document clustering process A computer information processing system utilizes parallel processors for organizing and clustering a large number of documents into a large number of clusters for information analysis and retrieval. After the documents are translated into electronic digi... | 01/26/1999 |
| 5762965 | Vaccines against intracellular pathogens using antigens encapsulated within biodegradble-biocompatible microspheres This invention relates to parenteral and mucosal vaccines against diseases aused by intracellular pathogens using antigens encapsulated within a biodegradable-biocompatible microspheres(matrix).... | 06/09/1998 |
| 5714515 | Pharmaceutical alpha-keto carboxylic acid compositions, method of making and use thereof A pharmaceutical composition comprising as an active phosphorylation poteal enhancing substance and an alpha-keto carboxylic acid or a pharmaceutically-acceptable salt thereof, its use and products containing the same.... | 02/03/1998 |
| 5705197 | Extraction process for producing PLGA microspheres A hybrid evaporation-extraction process for preparing microspheres of a p(DL-lactide-to-glycolide) biodegradable polymer, comprising: a. preparing a lyophilized biologically active material-sucrose matrix; adding acetonitrile solvent to biologically active ma... | 01/06/1998 |
| 5693343 | Microparticle carriers of maximal uptake capacity by both M cells and non-M cells In a solvent extraction process for preparing microspheres of a biodegrade polymer, the improvement comprising: preparing a homogenized antigen-sucrose matrix and adding a solvent to the sucrose-antigen matrix to form a solution; preparing a solution of ... | 12/02/1997 |
| 5536751 | Pharmaceutical alpha-keto carboxylic acid compositions method of making and use thereof A pharmaceutical composition comprising as an active phophorylation potenl enhancing substance and an alpha-keto carboxylic acid or a pharmaceutically-acceptable salt thereof, its use and products containing the same.... | 07/16/1996 |
| 5071759 | Hybridoma cell lines and monoclonal antibodies to clostridum difficile toxins A and B Monoclonal antibodies produced by a family of murine hybrid cell lines are cross-reactive with both toxin A and toxin B of Clostridium difficile. The monoclonal antibodies are useful in an immunoassay for toxin A and toxin B of C. difficile, a casual agen... | 12/10/1991 |
| 5055394 | Nucleic acid probe and method for the rapid detection of typhoid fever bacteria This invention relates to a nucleic acid probe and method for the rapid detection of typhoid fever bacteria by use of a nucleic acid hybridization probe, equivalent to the DNA region encoding the Vi antigen of enteric bacteria such as Salmonella typhi, S.... | 10/08/1991 |
| 4973734 | Carbaphens: aprophen analogs that are binary antidotes for organophosphate poisoning Novel carbaphens are provided of the formula ##STR1## wherein R is OH, OCON(CH3)2 or OCONHCH3, and R' is H, OH or 2 OCON(CH3)2, stereoisomers thereof, pharmaceutically-acceptable salts... | 11/27/1990 |
| 4960467 | Dermal substance collection device A dermal substance collection device (DSCD) is described which provides ms for the non-invasive, instantaneous and continuous monitoring of chemical substances which are present in a detectable amount in either or both interstitial fluid or sweat or whic... | 10/02/1990 |
| 4960496 | Atmospheric HCI monitor A device for performing rapid determinations on a real-time basis of about three to five seconds of the concentration of HCl in the atmosphere includes an air inlet conduit for sampling the HCl laden air, a pump for introducing trapping solution into the ... | 10/02/1990 |
| 4954449 | Human monoclonal antibody reactive with polyribosylribitol phosphate A human monoclonal antibody produced by a self-reproducing carrier cell, antibody being reactive with PRP capsular polysaccharide. Also disclosed is a process of preparing the antibody from the carrier cell, which is conveniently a hybridoma. Additional... | 09/04/1990 |
| 4906564 | Antigenic determinants recognized by antibodies obtained using a pathogenic agent or a derivative thereof that presents a restricted set of antigens A method provides peptides that are antigenic determinants identified by antibodies obtained using intact pathogenic agents that present a restricted set of antigens to surveillance by the immune system.... | 03/06/1990 |
| 4897403 | Antimalarial compositions and methods An antimalarial composition contains as the active ingredient a mixture of chemical compound effective in reversing the resistance of cancer cells to chemotherapy drugs and at least one antimalarial agent. A method for treating malaria in mammals comprise... | 01/30/1990 |
| 4885256 | Monoclonal antibodies to cholesterol and methods Monoclonal antibodies which demonstrate specific reactivity to cholesterol and methods for the detection of high levels of cholesterol by contacting biological specimens containing cholesterol with the monoclonal antibodies and measuring the formation of ... | 12/05/1989 |
| 4843114 | Rubber compound for tracked vehicle track pads A highly improved elastomeric composition, process, and articles made thef, wherein the novel composition is characterized by greatly increased wear longevity, thermomechanical stability, highly improved tear and tensile strength at high temperature usea... | 06/27/1989 |
| 4824666 | Method of large scale growth of toxoplasmic microorganisms A method of producing large scale growth of parasites of the genus Toxoplasma is disclosed which comprises inoculating the microorganisms into a non-adherent human cell line, such as a monocytoid lymphoma cell line, and maintaining the cell line in tissue... | 04/25/1989 |
| 4819645 | Dermal substance collection method A dermal substance collection device (DSCD) is described which provides ms for the non-invasive, instantaneous and continuous monitoring of chemical substances which are present in a detectable amount in either or both interstitial fluid or sweat or whic... | 04/11/1989 |
| 4808598 | Method for inducing protection in an animal against cyanide poisoning using 8-aminoquinolines This invention is directed to a method for inducing protection in an animal gainst poisoning resulting from exposure to toxic levels of cyanide comprising orally administering to said animal a therapeutically effective amount of a compound having the formu... | 02/28/1989 |
| 4805468 | Fiber collection and storage device This invention is directed to a fiber collection and storage device comprising in combination (1) a stable, transparent carrier base material preponderate on a surface thereof with a grid and label, the grid having uniquely identified areas wherein collec... | 02/21/1989 |
| 4791135 | Novel antimalarial dihydroartemisinin derivatives This invention relates to novel dihydroartemisinin derivatives, including their pharmaceutically-acceptable salts, which are therapeutically-effective in the pre- and post-treatment of malarial infections.... | 12/13/1988 |
| 4777166 | 2-acetylpyridine thiosemicarbazone compositions as anitviral agents This invention relates to various compositions, comprising a 2-acetylprid thiosemicarbazone and a diol, which are useful in the treatment of viral infections.... | 10/11/1988 |
| 4758387 | Disposal of solid propellants Solid propellant is first placed in a closed container with a solution of ter and detergent. A water slurry is then created by injecting compressed air in superheated steam into the solution to place the propellant and solution under several atmospheres o... | 07/19/1988 |
| 4744982 | Human monoclonal antibody reactive with polyribosylribitol phosphate A human monoclonal antibody produced by a self-reproducing carrier cell, the antibody being reactive with PRP capsular polysaccharide. Also disclosed is a process of preparing the antibody from the carrier cell, which is conveniently a hybridoma. Addition... | 05/17/1988 |
| 4739069 | 2-acetyl-and 2-propionylpyridine thiosemicarbazones This invention relates to various 2-acetyl- and 2-propionylpyridine thiosemicarbazones which are substituted on the 4-nitrogen atom. These compounds are useful in the treatment of gonorrhea and, in addition, many are useful either in the treatment of mala... | 04/19/1988 |
| 4725235 | Marksmanship training apparatus The embodiments of the invention provide mechanical and electrical appara for inexpensively and swiftly converting conventional firearms temporarily into marksmanship training devices. Illustratively, a number of different devices are shown for attaching... | 02/16/1988 |
| 4713391 | Azabicyloalkane phenyl substituted alkane carboxylates, their preparation and use as anticholinergic agents This invention relates to novel compositions, their preparation and the use thereof as anticholinergic agents in the treatment or prophylaxis of organophosphate or nerve gas poisoning in animals. These compositions and pharmaceutical preparations containi... | 12/15/1987 |
| 4707357 | Immunologically active peptides capable of inducing immunization against malaria and genes encoding therefor An immunologically active substantially pure peptide capable of inducing in human an immune response which is cross reactive with and protective against infection by a malaria parasite, wherein the peptide contains at least 2 consecutive repeats of a sequ... | 11/17/1987 |
| 4706676 | Dermal substance collection device A dermal substance collection device (DSCD) is described which provides means for the non-invasive, instantaneous and continuous monitoring of chemical substances which are present in a detectable amount in either or both interstitial fluid or sweat or wh... | 11/17/1987 |
| 4707543 | Process for the preparation of detoxified polysaccharide-outer membrane protein complexes, and their use as antibacterial vaccines Process for preparing a detoxified polysaccharide-outer membrane protein complex from bacterial envelopes; the so-obtained products which are useful as vaccines against infection by the same bacteria and method for protecting animals against the same infe... | 11/17/1987 |
| 4707199 | Non nitroglycerin-containing composite-modified double-base propellant The glycidyl azide polymer produced by hydrolysis of glycidyl chloride fowed by reaction with sodium azide is employed in a crosslinked composite-modified double-base propellant composition both in the casting powder portion and casting solvent portion a... | 11/17/1987 |
| 4698106 | Method for the manufacture of oxidizers of very large surface area and their use in high burning rate propellants Solid oxidizer particles of ultrahigh surface area are produced by an etching process which includes employing selective extractants in a process which causes the formation of indentations and/or cavities on the surfaces of the oxidizer particles, and cre... | 10/06/1987 |
| 4665173 | 2-acetyl- and 2-propionylpyridine selenosemicarbazones This invention relates to novel 2-acetyl- and 2-propionylpyridine selenosemicarbazones. These compounds are useful as antimalarial and antileukemic agents. Also disclosed are several synthetic procedures used to prepare the selenosemicarbazones.... | 05/12/1987 |
| 4659738 | Topical prophylaxis against schistosomal infections An improved method is provided for the prevention of schistosomal infecti in animals. The topical application of a 2-hydroxy-benzoic anilide provides prophylactic protection against penetration by infective cercariae of the parasitic worms.... | 04/21/1987 |
| 4659708 | Anti-leishmanial lepidine derivatives The subject 8-[6-(N-heterocyclic-substituted)hexylamino]-6-methoxy lepidine erivatives have the formula: ##STR1## wherein Z represents methyl or, together with the two contiguous carbon atoms, the benzo moiety of a benzopiperazinyl derivative when Y i... | 04/21/1987 |
| 4657903 | Transition metal complexes of the selenium analogs of 2-acetyl- and 2-propionylpyridine thiosemicarbazones useful for treating malarial infections and leukemia This invention relates to novel transition metal complexes of 2-acetyl- and -propionylpyridine thiosemicarbazones, their selenium analogs. These compounds are useful as antimalarial and antileukemic agents. Also disclosed are several synthetic procedures u... | 04/14/1987 |
| 4655860 | A processing method for increasing propellant burning rate The effectiveness of the burning rate accelerator, iron oxide (Fe2 Ob.3), is enhanced, and a markedly improvement in the mechanical properties of a propellant composition are simultaneously achieved as a result of grinding a composite propella... | 04/07/1987 |
| 4655235 | Chemical contamination monitor A chemical contamination monitoring system is provided for monitoring and decontaminating protective clothing that has been exposed to toxic chemicals. The system includes a decontamination chamber in which the clothing is supported and a spray assembly, ... | 04/07/1987 |
