Quotables
"What, sir, would you make a ship sail against the wind and currents by lighting a bonfire under her deck? I pray you, excuse me, I have not the time to listen to such nonsense."
Napoleon Bonaparte ; When told of the Robert Fulton steamboat
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 8183361 | Oligonucleotide-containing pharmacological compositions and their use The present invention relates to methods and compositions containing oligonucleotides suitable for administration to humans and other mammals. ... | 05/22/2012 |
| 8168393 | Compositions and methods for diagnosing tumors using LEDGF/p75 The invention provides methods for diagnosing tumors in mammals using a reagent that bind to LEDGF/p75 or to a nucleic acid encoding LEDGF/p75. For example, the tumor may be located in the CNS, the prostate, the skin, the bone marrow, or the gut of the mammal. Also ... | 05/01/2012 |
| 8148080 | Gene and protein relating to hepatocellular carcinoma and methods of use thereof The present invention provides a novel human gene ZNFN3A1 whose expression is markedly elevated in a great majority of HCCs compared to corresponding non-cancerous liver tissues. The gene encodes a protein having a zinc finger domain as well as a SET domain and has ... | 04/03/2012 |
| 8129344 | Method of reducing cell death by administering a Sfrp polypeptide A purified paracrine factor of a mesenchymal stem cell, such as a Secreted frizzled related protein (Sfrp) is useful to reduce cell death an/or tissue injury associated with ischemic condtions. ... | 03/06/2012 |
| 8129128 | Immunoassay reagent compositions for diagnosing multiple sclerosis This application is related to immunoassay reagent compositions comprising a glycan reagent for diagnosing multiple sclerosis. ... | 03/06/2012 |
| 8097596 | Compositions and methods for the treatment of muscle wasting The invention provides compositions of oligonucleotides targeted at genes involved in muscle wasting and/or muscle growth. In some embodiments, the oligonucleotides are modified. In some embodiments, the compositions contain one, or more than one, oligonucleotide. T... | 01/17/2012 |
| 8093262 | Use of huperzine for disorders Methods and compositions containing huperzine are used to prevent and alleviate neuropathic pain. The invention is also directed to methods and compositions for using huperzine for the prevention and/or treatment of neuropathic pain and orthostatic hypotension. ... | 01/10/2012 |
| 8076451 | Selective delivery of molecules into cells or marking of cells in diseased tissue regions using environmentally sensitive transmembrane peptide A polypeptide with a predominantly hydrophobic sequence long enough to span a membrane lipid bilayer as a transmembrane helix (TM) and comprising one or more dissociable groups inserts across a membrane spontaneously in a pH-dependant fashion placing one terminus in... | 12/13/2011 |
| 8067237 | Scaffolds for cell transplantation A device that includes a scaffold composition and a bioactive composition with the bioactive composition being incorporated into or coated onto the scaffold composition such that the scaffold composition and/or a bioactive composition controls egress of a resident c... | 11/29/2011 |
| 8050869 | Profile searching in nucleic acid sequences using the Fast Fourier Transformation The invention provides methods for detecting known blocks of functionally aligned protein sequences in a test nucleic acid sequence, e.g., in an uncharacterized EST. The method can detect the presence of known blocks of functionally aligned protein sequences in a te... | 11/01/2011 |
| 8048639 | Method for evaluating risk in multiple sclerosis The invention relates to methods and reagents for diagnosing and assessing the prognosis of multiple sclerosis. ... | 11/01/2011 |
| 7939282 | Methods for detecting sepsis Compositions and methods for detecting sepsis by contacting a subject-derived sample with a ligand that binds to GRK and determining the concentration of GRK in the sample. An increase in the concentration of GRK compared to that of a normal, healthy control sample ... | 05/10/2011 |
| 7935528 | Liver stem cell The invention provides a primary liver stem cell and a cell doublet consisting of a hepatocyte and the stem cell, both of which are derived from normal liver tissue. Methods of isolating the cells, genetically altering the cells, and using the cells for transplantat... | 05/03/2011 |
| 7871763 | Hepatocellular carcinoma-related genes and polypeptides, and method for detecting hepatocellular carcinomas Genes up-regulated in hepatocellular carcinomas and polypeptides encoded by these genes are provided. Vectors, transformants and methods for producing the recombinant polypeptides are also provided. Probes and primers of these genes and antibodies against the polype... | 01/18/2011 |
| 7854927 | Methods and compositions for the dietary management of autoimmune disorders The present invention describes the use of lactic acid bacteria, particularly lactic acid producing members of the genus Bacillus, in treating digestive-related immune disorders by downregulating of cytokines and by inhibiting pathogenic or deleterious microo... | 12/21/2010 |
| 7833513 | Treatment of Alzheimer's Disease This invention relates to methods for diagnosing Alzheimer's Disease (AD) by determining the level or function of insulin, insulin-like growth factors, their receptors and/or their downstream signaling molecules. The invention further relates to methods for the trea... | 11/16/2010 |
| 7807176 | Polypeptide promoting vascular endothelial cell growth It is intended to provide a novel polypeptide having an activity of growing vascular endothelial cells, an activity of promoting transcription form c-fos promoter, an activity of promoting transciption from VEGF promoter and/or an angiogenic activity; a polynucleoti... | 10/05/2010 |
| 7807151 | Probiotic, lactic acid-producing bacteria and uses thereof The present invention discloses compositions and methodologies for the utilization of probiotic organisms in therapeutic compositions. More specifically, the present invention relates to the utilization of one or more species or strains of lactic acid-producing bact... | 10/05/2010 |
| 7767392 | Gene and protein relating to hepatocellular carcinoma and methods of use thereof The present invention provides a novel human gene ZNFN3A1 whose expression is markedly elevated in a great majority of HCCs compared to corresponding non-cancerous liver tissues. The gene encodes a protein having a zinc finger domain as well as a SET domain and has ... | 08/03/2010 |
| 7767203 | Methods for the dietary management of irritable bowel syndrome and carbohydrate malabsorption The invention relates generally to digestive disorders, and in particular to methods for treating irritable bowel syndrome by increasing carbohydrate absorption by administering a composition containing a Bacillus coagulans bacterium. ... | 08/03/2010 |
| 7713726 | Inhibition of pathogens by probiotic bacteria Compositions containing a lactic acid-producing bacterial strain, e.g., Bacillus coagulans for inhibition of pathogenic bacterial infections. Spores or extracellular products produced by the bacterial strains are also useful as inhibitory agents. ... | 05/11/2010 |
| 7708988 | Probiotic, lactic acid-producing bacteria and uses thereof The present invention discloses compositions and methodologies for the utilization of probiotic organisms in therapeutic compositions. More specifically, the present invention relates to the utilization of one or more species or strains of lactic acid-producing bact... | 05/04/2010 |
| 7700093 | Methods for increasing lactose digestion The invention relates generally to digestive disorders, and in particular to methods for treating irritable bowel syndrome by increasing carbohydrate absorption by administering a composition containing a Bacillus coagulans bacterium. ... | 04/20/2010 |
| 7691996 | Three component chimeric antisense oligonucleotides This invention relates to antisense oligonucleotides that target mRNAs in cells as substrates for the cellular enzyme RNase H and thereby cause specific degradation of the targeted mRNA. The oligonucleotides have three components: an RNase H activating region, a com... | 04/06/2010 |
| 7653428 | Methods for diagnosing a neurodegenerative condition The invention provides a method of diagnosing, prognosing, staging, and/or monitoring a mammalian amyloidogenic disorder or a predisposition thereto by detecting a protein or polypeptide aggregate in the cortical and/or supranuclear regions of an ocular lens of the ... | 01/26/2010 |
| 7638128 | Method of enhancing cardiac tissue repair by administering a SFRP polypeptide A purified paracrine factor of a mesenchymal stem cell, such as a Secreted frizzled related protein (Sfrp) is useful to reduce cell death an/or tissue injury associated with ischemic conditions. ... | 12/29/2009 |
| 7608414 | Method for diagnosing and prognosing inflammatory bowel disease and crohn's disease Disclosed are methods for diagnosing and prognosing Inflammatory Bowel disease or Crohn's disease (CD) by measuring levels of antibodies to glycans in a biological sample. ... | 10/27/2009 |
| 7592150 | Method for diagnosing diseases based on levels of anti-glycan antibodies Disclosed are methods for diagnosing Crohn's disease (CD) or anti-phospholipid syndrome by measuring levels of antibodies to glycans in a biological sample. ... | 09/22/2009 |
| 7544363 | Topical compositions containing extracellular products and uses thereof The present invention discloses compositions derived from an isolated Bacillus species spores, or an extracellular product of Bacillus coagulans comprising a supernatant or filtrate of a culture of said Bacillus coagulans strain, suitable for to... | 06/09/2009 |
| 7029906 | Carbonyl stress-ameliorating agents Carbonyl stress-ameliorating agents have been provided, which contain an enzyme having a glyoxalase I activity and a carbonyl compound-reducing agent as the active ingredients. The carbonyl stress-ameliorating agents of the present invention rapidly eliminate carbon... | 04/18/2006 |
| 7537900 | Method for diagnosing multiple sclerosis Disclosed is a method for diagnosing multiple sclerosis and more particularly to a method for diagnosing multiple sclerosis by measuring levels of antibodies to glycans in a biological sample. ... | 05/26/2009 |
| 7507402 | Topical use of probiotic spores to prevent or control microbial infections Compositions including an isolated Bacillus species, spores or an extracellular product of B. coagulans, suitable for topical application, for inhibiting growth of yeast, fungus, bacteria or Herpes simplex virus are disclosed. Methods of inhibiting gro... | 03/24/2009 |
| 7503211 | Driven musculoskeletal joint testing An apparatus for testing natural, partially artificial, or artificial musculoskeletal joints is provided as well as a method for using the same. In one aspect, the system employs a weighted, articulated apparatus, such as a pendulum, moving in response to a driving ... | 03/17/2009 |
| 7416889 | Methods and compositions for repairing cartilage Disclosed is a method for inducing repair of a joint tissue in a mammal includes the steps of removing a sample of synovial membrane from a joint of the mammal, isolating type B synoviocytes from the membrane to yield a suspension of enriched type B synoviocytes, an... | 08/26/2008 |
| 7374753 | Probiotic lactic acid bacterium to treat bacterial infections associated with SIDS Compositions including a non-pathogenic lactic acid-producing bacteria, such as a Bacillus species, spores or an extracellular product of B. coagulans, formulated for oral administration to the intestinal tract for inhibiting bacterial gastrointestinal... | 05/20/2008 |
| 7371407 | Use of Emu Oil and its various fractions as a carrier for antifungal, antibacterial, and antiviral medications and preparations An animal-derived lipid is disclosed that is useful as a carrying agent for anti-microbial formulations. Pharmaceutical and other preparations including Emu Oil are also described as profoundly useful components in anti-bacterial, anti-fungal, and anti-viral treatme... | 05/13/2008 |
| 7345156 | Hepatocellular carcinoma-related genes and polypeptides, and method for detecting hepatocellular carcinomas Genes up-regulated in hepatocellular carcinomas and polypeptides encoded by these genes are provided. Vectors, transformants and methods for producing the recombinant polypeptides are also provided. Probes and primers of these genes and antibodies against the polype... | 03/18/2008 |
| 7329544 | Plant lesion formation suppressing gene, Sp17 and use thereof The present inventors successfully isolated a lesion formation suppressing gene (Spl7) from rice via a linkage analysis. It was revealed that introduction of this gene into plants enhances their heat stress resistance and that lesion formation can be suppressed.... | 02/12/2008 |
| 7326733 | Methods for increasing bone density Methods and compounds for remodeling bone and treating osteopenic conditions are described. Methods and compounds for increasing bone mineral density by decreasing serotonin levels in osteoblasts are also described. ... | 02/05/2008 |
| 7326679 | Anticancer peptide compositions The invention provides compositions and methods for inhibiting angiogenesis associated with tumors and reducing tumor growth. ... | 02/05/2008 |
