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| Number | Title | Issue Date |
| 6333189 | Method of making an electrotransport device Method of making an electrotransport device containing an analog of a parent polypeptide having one or more amino acid residues substituted relative to the parent polypeptide with an amino acid residue selected from the group consisting of proline, glycin... | 12/25/2001 |
| 6313092 | Method for increasing the electrotransport flux of polypeptides Methods for modifying polypeptide agents to enhance their transdermal electrotransport flux are provided. The polypeptide is modified by reducing the potential of the polypeptide for forming -helical or ଲ-sheet segments. In particular, amino ... | 11/06/2001 |
| 6230051 | Device for enhancing transdermal agent delivery or sampling A percutaneous agent delivery or sampling device comprising a sheet having a plurality of microblades for piercing the skin for increasing transdermal flux of an agent. The microblades having a relatively sharp angled leading edge which transitions to a r... | 05/08/2001 |
| 6219574 | Device and method for enchancing transdermal sampling A percutaneous agent sampling device and method are provided. The device comprises a collector and a sheet having a plurality of microblades for piercing the skin for increasing transdermal flux of an agent.... | 04/17/2001 |
| 6195582 | Electrotransport device electrode assembly having lower initial resistance The present invention relates generally to an electrotransport device for transdermally or transmucosally delivering a beneficial agent (e.g., a drug) to the body surface of a patient or for transdermally or transmucosally sampling a body analyte. Most pa... | 02/27/2001 |
| 6175763 | Electrotransport drug delivery device having tactile signaling means An electrotransport system (20) for delivery of a drug through the skin (63) of a patient includes a tactile signal generator (36) for generating and transmitting a tactile signal to the skin of a patient upon the occurrence of an event associated with th... | 01/16/2001 |
| 6163720 | Layered rate controlling membranes for use in an electrotransport device The disclosed invention relates to an improved electrotransport device. The improvement relates to a membrane assembly including a low porosity membrane adhered or sealed to one or two high porosity membranes. The high porosity membranes protect the low p... | 12/19/2000 |
| 6136327 | Stereospecific delivery of a drug using electrotransport Preferential delivery via electrotransport of a preferred isomeric form of a pharmaceutically active chiral compound from a mixture of the isomeric forms of said compound is provided. A method of decreasing the delivery via electrotransport of a less pref... | 10/24/2000 |
| 6086572 | Electrotransport device and method of setting output A two-part electrotransport drug delivery device (20) is comprised of a controller (22) which has a plurality of different electronic outputs. The controller (22) is adapted to be mechanically and electrically coupled to a plurality of different drug-cont... | 07/11/2000 |
| 6071508 | Preparation of formulations for electrotransport drug delivery A method is provided for preparing drug formulations suitable for electrotransport drug delivery. The drug to be delivered, present in salt form, is contacted with an ion exchange material prior to incorporation into the reservoir (26) of an electrotransp... | 06/06/2000 |
| 6049733 | Electrotransport system with ion exchange material competitive ion capture An electrotransport apparatus using dispersed ion exchange material (19,83) is disclosed. The ion exchange material (19,83) may be dispersed in either the donor electrode assembly (10), the counter electrode assembly (10) or both electrode assemblies. The... | 04/11/2000 |
| 6039977 | Pharmaceutical hydrogel formulations, and associated drug delivery devices and methods Pharmaceutical hydrogel formulations containing polyvinyl alcohol are provided. The formulations may serve as rug reservoirs in electrotransport drug delivery systems or passive transdermal systems, or they may be used in a variety of other types of dosag... | 03/21/2000 |
| 5995869 | Reduction of skin sensitization in electrotransport drug delivery A device and method are provided for reducing or preventing skin sensitization in electrotransport drug delivery. The method involves co-administration of a countersensitizing agent, comprising cis-urocanic acid or an analog thereof, with the drug deliver... | 11/30/1999 |
| 5993435 | Device and method of iontophoretic drug delivery A selectively permeable membrane (14) is positioned between the agent reservoir (15) and the electrode (11) of a donor electrode assembly (8) in an iontophoretic delivery device (10). Optionally, an electrolyte reservoir (13) is positioned intermediate th... | 11/30/1999 |
