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| Number | Title | Issue Date |
| 8180444 | Enhanced PhotoDynamic Therapy with immune system assist A photodynamic therapy (PDT) method to treat primary sites of hyperproliferative tissue and induce long term, tumor specific immunity for regression and eradication of distant metastases is disclosed. The improved treatment regimen comprises the partial or fractiona... | 05/15/2012 |
| 8153111 | Photo-triggered release of active substances from dendrimer-photosensitizer complexes Compositions of dendrimer-photosensitizer complexes including therapeutic molecules, and methods for their synthesis and use are disclosed. The therapeutic molecules and the photosensitizers are each covalently attached to the dendrimer at its end-groups, essentiall... | 04/10/2012 |
| 7751668 | Microstructuring of an optical waveguide for producing functional optical elements The invention relates to a method for microstructuring an optical waveguide having a first cross-sectional region with a first refractive index, a second cross-sectional region with a second refractive index, and a boundary region in the transition from the first to... | 07/06/2010 |
| 7033263 | Pivot action bivalve opening system A system for opening bivalves employing pivot action to drive a sharp stainless steel knife blade through a shellfish is provided. Key components are the knife blade which is securely connected to a pivot shaft that is anchored in two pivot support posts. The cuttin... | 04/25/2006 |
| 7032247 | Bib-garment system A protective bib-garment system is described wherein a bib is detachable from the garment it protects, but can not rotate around the wearer's neckline. It thereby provides better protection and safety for the user. The bibs are easily attached or removed for separat... | 04/25/2006 |
| 7354599 | Liposomal formulations of hydrophobic photosensitizer for photodynamic therapy Pharmaceutical liposomal formulations are described for photodynamic therapy comprising a, hydrophobic porphyrin photosensitizer, a monosaccharide and one or more synthetic phospholipids, which are stable in storage especially through freeze-drying process. The lipo... | 04/08/2008 |
| 7351242 | Active endoscopic photodynamic therapy devices; systems and method An active endoscopic system is disclosed containing an electromagnetic radiation system located at the distal end of the endoscopic device allowing for variable intensity application of desired wavelengths in the application of PhotoDynamic Therapy (PDT) over a broa... | 04/01/2008 |
| 7331983 | Fiber assisted irradiation system and method for biostimulation The present invention provides a system and method for improved biostimulative effect through the use of low mode/oligomode fibers to transport coherent light to a treatment site. Oligomode fibers or groups/bundles of oligomode waveguides for the relevant irradiatio... | 02/19/2008 |
| 7180922 | Safety system for focused energy applications A system and method is disclosed for improving the safety of directionally sensitive medical and industrial applications, such as laser applications, and cutting or surfacing tools. A system of electromagnetic radiation safety beam emitters and detectors is used to ... | 02/20/2007 |
| 7177695 | Early stage wound healing using electromagnetic radiation A device and method is disclosed for the treatment of early stage wounds, i.e. those wounds that have resulted in little or no breach of the skin tissue. The invention utilizes non-ablative laser or non-coherent electromagnetic radiation applied to a stage one or tw... | 02/13/2007 |
| 6975791 | Fiber laser pumping device An improved device and method to pump fiber lasers in order to enhance performance and reliability is provided. A fiber laser is bent into a coil having a moderate curvature so as to avoid radiation losses. A cladding is partly polished to produce coupling surfaces ... | 12/13/2005 |
| 6948815 | Laser safety contact lenses Individually marked contact lenses for protection of one's eyes from harmful radiation are provided. Contact lenses are coated or treated to be absorptive or reflective to a preselected wavelength or wavelengths. The lenses contain one or more identification areas o... | 09/27/2005 |
| 6949581 | Water-soluble mono-PEGylated tetrapyrrole derivatives for photodynamic therapy and method of production Water-soluble mono-PEGylated tetrapyrrole derivatives are disclosed, having a formula given by formula 1, 2, or 3 in the specification. A method to produce the above water-soluble mono-PEGylated compounds is also disclosed, comprising an interaction of a tetrapyrrol... | 09/27/2005 |
| 6942656 | Method for accurate optical treatment of an eye's fundus A system and method is provided to accurately treat sites on an eye's retina employing computer based image generation, processing and central control means in conjunction with diode laser sources and optical fibers. The system and method accurately determine geomet... | 09/13/2005 |
| 6928839 | Method for production of silica optical fiber preforms A device and method is disclosed for manufacturing optical fiber preforms utilizing microwave plasma assisted chemical vapor deposition. Precursor gas is introduced to the face of a vertically mounted dielectric rod, and a plasma is struck by means of simultaneous e... | 08/16/2005 |
| 6830580 | Fiber assisted irradiation system and method for biostimulation The present invention provides a system and method for improved biostimulative effect through the use of single mode fibers to transport coherent light to a treatment site. Single mode fibers or groups/bundles of single mode waveguides for the relevant irradiation w... | 12/14/2004 |
| 6813050 | Rotary mirror array for fast optical tomography A high speed, high duty cycle, linear, optical scanning device suitable for optical coherence tomography, optical coherence microscopy and confocal microscopy is presented. For the microscopy applications stable, periodic scanning is achieved by using a rotary mirro... | 11/02/2004 |
| 6810184 | Device and method to scatter optical fiber output The present invention provides improved diffusion tips for optical fibers and methods of making the same. Nanoporous silica clad optical fibers are used to make fibers having integrally formed diffusion tips and diffusion tips that can be fused to other fibers. The ... | 10/26/2004 |
| 6561808 | Method and tools for oral hygiene A method and material for self-cleaning of the teeth and mouth using a source of light in the visible range in conjunction with a photosensitive oral hygiene composition possessing a broad absorption spectrum in the visible range. The invention selectivel... | 05/13/2003 |
| 6421361 | Tunable diode laser system for photodynamic therapy A tunable medical laser diode system for activating PhotoDynamic Therapy (PDT) compounds is disclosed. A tunable medical laser diode system for activating PhotoDynamic Therapy (PDT) compounds and other moderate or low energy multiple wavelength applicatio... | 07/16/2002 |
| 6383179 | Diode laser scalpel A device that simultaneously incises an area and cauterizes the desired tissue. The device incorporates laser energy by some means into a mechanical scalpel so that the incised area is cauterized as well. For example, a laser source is coupled by some mea... | 05/07/2002 |
| 6343174 | Laser delivery system with optical fibers having fluid delivery channels Briefly stated, the present invention provides a medical laser delivery system that incorporates fluid delivery channels within the optical fiber structure so as to bring fluids directly to the site of laser power delivery. The channel or channels may pas... | 01/29/2002 |
| 6261310 | Laser safe treatment system In the present invention a laser treatment system is provided that can be used in any clinical environment without the necessity of personal safety equipment. Furthermore, the present invention provides a large amount of control to the operator/technician... | 07/17/2001 |
| 6208781 | Fiber optic transmission system for high power laser A fiber optic transmission system for high laser power transmission is described. A micro-structure, whose pre-determined features are characterized by a preferred shape, depth, and peak-to-peak distance, is introduced into an input end surface of an opti... | 03/27/2001 |
| 6200332 | Device and method for underskin laser treatments A device and method for underskin laser treatment that is minimally invasive, versatile and precise, that allows for underskin laser treatment with only minimal insertions into the area of treatment. For example, an entire area may be treated with one ins... | 03/13/2001 |
| 6165205 | Method for improved wound healing A laser non-ablative laser method that will accelerate and improve wound healing, particularly in situations where complicating factors are present. In particular, it is believed that the present invention produces selective papillary dermal injury which ... | 12/26/2000 |
| 6097540 | Frequency conversion combiner system for diode lasers A frequency conversion diode beam combiner system is provided to multiplex several frequency converted laser beams and therefore keep the beam-quality of a single emitter. This multiplexing is physically impossible with free propagating beams. Both transf... | 08/01/2000 |
| 6086363 | Device and method to treat oral disease in small animals A laser system and method are described that will improve dental treatments in small animals, particularly in situations where periodontal disease has progressed to the advanced stages of periodontitis and when dental pulp is exposed by fracture or diseas... | 07/11/2000 |
| 6039728 | Working shaft for photo-thermal therapy An optical working shaft system. The system includes a working shaft for insertion into a working tube of at least one of an endoscope and a catheter. The working shaft has a distal end defining a distal area in a vicinity thereof, and further includes: a... | 03/21/2000 |
| 6018533 | Optical fiber and integrated optic lasers with enhanced output power The invention describes a method of single-transverse-mode generation for waveguide lasers of various kinds having a large cross section of their active core and thus providing a possibility of efficient pump of the active core region. This results in a l... | 01/25/2000 |
| 6016197 | Compact, all-optical spectrum analyzer for chemical and biological fiber optic sensors An optical spectrum analyzer based on optical processing of the far field interference pattern from two beams irradiated by light transmitting waveguides is described. The spectrum analyzer can operate in UV, VIS, NIR and MIR ranges of spectrum and it can... | 01/18/2000 |
| 6011890 | High power, multi-diode laser system The present invention teaches a diode laser system which utilizes optical fibers arranged in bundles whereby one group is bundled in a central section and one or more groups are arranged in a concentric circle or other symmetrical shape or configuration a... | 01/04/2000 |
| 6005717 | Diode laser beam combiner system A small, scalable, and inexpensive semiconductor diode laser system is described that includes a diode laser beam combiner comprising a cylindrical microlens, a lens array, and a fan window that optically combines energy outputs of at least two diode lase... | 12/21/1999 |
| 5965216 | Method of producing diamond-like-carbon coatings A rf plasma enhanced chemical vapor deposition process is presented, wherein a precursor gas stream having a high helium content produces hard, wear resistant, hermetically sealing, high refractive index Diamond-Like-Carbon (DLC) coatings on numerous subs... | 10/12/1999 |
