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Patent No. 5205055

Pneumatic Shoe Lacing Apparatus

This invention provides a pneumatic shoe lacing apparatus for the pneumatic lacing of shoe.

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Attorney: Arwine; Elizabeth


Number of patents: 247
Last date: May 22, 2012

1              
NumberTitleIssue Date
8183358Puumala virus full-length M segment-based DNA vaccines
The invention contemplates a new synthetic, codon-optimized Puumala virus (PUUV) full-length M gene open reading frame (ORF) that encodes a unique consensus amino acid sequence. The PUUV ORF was cloned into a plasmid to form the first stable PUUV full-length M gene ...
05/22/2012
8172909Modular prosthetic foot
A modular prosthetic foot characterized by an ankle component; a forefoot component having a circular part with a rounded top surface and at least one flat side surface, said circular part being connected to a rear part of the forefoot component; a forefoot cushion ...
05/08/2012
8157785Burn patient resuscitation system
A method and system for operating a semi-closed loop and/or a closed loop resuscitation of a burn patient in view of patient information and other physiological data gathered as part of the method and/or by the system. The method in at least one embodiment includes ...
04/17/2012
8153397Recombinant light chains of botulinum neurotoxins and light chain fusion proteins for use in research and clinical therapy
The present invention relates to the construction, expression, and purification of synthetic or recombinant light chain (LC) botulinum neurotoxin genes from all botulinum neurotoxin serotypes. The methods of the invention can provide 1.1 g of the LC per liter of cul...
04/10/2012
8110354Use of invaplex to transport functional proteins and transcriptionally active nucleic acids across mammalian cell membranes in vitro and in vivo
The in vivo and in vitro use of Invaplex to transport materials, including functional proteins and biologically active nucleic acids, across eukaryotic cell membranes. The eukaryotic cells include a variety of cell types, e.g. insect, reptile, fish, mammal and tumor...
02/07/2012
8105808Anaerobic microbial composition and methods of using same
A microbial composition for concurrent dechlorination of a mixture of chlorinated ethanes and chlorinated ethenes includes a isolated consortium of bioremediative microorganisms comprising strains of microorganism comprising Clostridium, Acetobacterium, Dehalobac...
01/31/2012
8067202Bacterial superantigen vaccines
The present invention relates to genetically attenuated superantigen toxin vaccines altered such that superantigen attributes are absent, however the superantigen is effectively recognized and an appropriate immune response is produced. The attenuated superantigen t...
11/29/2011
8030287DNA vaccine against North American spring viremia of carp virus
In this application is described a novel DNA vaccine for Spring viremia of carp virus. The candidate vaccine a SVCV glycoprotein (G) gene from the North Carolina isolate. The DNA vaccine provides protection in vaccinated fish against challenge with the SVCV. ...
10/04/2011
8012987Indolo[2,1-b] quinazole-6,12-dione antimalarial compounds and methods of treating malaria therewith
Compounds, compositions and methods are provided for treating malaria parasites in vitro and in vivo by administering indolo [2,1-b]quinazoline-6,12-dione compounds of Formula I. wherein A, B, C, D, B, F, G and H are indepe...
09/06/2011
7999001Antiviral compounds and methods of using thereof
Disclosed herein are compounds which exhibit antiviral activity against a plurality of viruses belonging to different families such as Bornaviridae, Filoviridae, Paramyxoviridae, Rhabdoviridae, Arenaviridae, Bunyaviridae, Orthomyxoviridae, and Poxviridae. Thus, meth...
08/16/2011
7997904Obstetrics simulation and training method and system
In the modern practice of obstetrics, the military is in the position of having experts in both simulation training for obstetric emergencies and teamwork training. The military has the potential to train better and provide the safest environment possible with these...
08/16/2011
7993917Method for obtaining a cellular product from a cell or a tissue using protein-free medium
Methods for the diagnosis of visceral, cutaneous and canine leishmaniasis in a subject suspected of being infected with the parasitic protozoa Leishmania is disclosed. Disclosed are antibody-capture enzyme-linked immunosorbent assays (ELISAs) for the detectio...
08/09/2011
7976832Active topical skin protectants containing amines, polyalkenimines and /or derivatives
A topical skin protectant formulation containing a barrier cream and an active moiety for protecting warfighters and civilians against all types of harmful chemicals, specifically chemical warfare agents (CWA). The active moiety is an amine, polyalkenimines and/or d...
07/12/2011
7956086Methods for the formulation and manufacture of artesunic acid for injection
A method for the manufacture of a sterile intravenous or intramuscular formulation of artesunic acid and the formulation are the subject of this invention. First the artesunic acid powder is sterilized with ethylene oxide and placed into a sterile container. The con...
06/07/2011
7933554Systems and methods for short range wireless communication
A magnetic induction data transmission network comprising a master hub, at least one sensor node communicatively coupled to the master hub and a magnetic induction coil preferably adapted to be worn about a bodypart of a subject such as an individual's waist or neck...
04/26/2011
7931919Method of producing glycine-stabilized, lyophilized plasma
The invention is directed to stabilized whole-cell plasma, which retains the integrity and overall stability of the proteins and other macromolecules of the plasma. Stabilization is accomplished by the addition of glycine to plasma which allows for stabilization pri...
04/26/2011
7899687System and method for handling medical information
A system and method that are used for creating a longitudinal medical record for an injured person. The system includes in at least one embodiment a plurality of mobile computing devices. The mobile computing devices having an interface for receiving information fro...
03/01/2011
7897162Arthropod repellent pharmacophore models, compounds identified as fitting the pharmacophore models, and methods of making and using thereof
Disclosed herein is a pharmacophore model for arthropod repellent activity and methods of making and using thereof. The pharmacophore comprises two hydrophobic aliphatic functions, one aromatic function and one hydrogen bond acceptor function. The pharmacophore mode...
03/01/2011
7895977Device for the safe handling of nonhuman primates
A device for the safe handling of nonhuman primates includes a transparent elongated body having a top end and a bottom end. A ventilated lid is attached to the top end of the body by means of a hinge and includes a positive locking arrangement. The bottom end of th...
03/01/2011
7887330Trauma training system
A system for simulating one or more hemorrhages in order to provide a more dynamic and realistic hemorrhage simulation in order to train medical personnel and other critical care givers, such as first responders, medics, and emergency medical technicians (EMTs) on t...
02/15/2011
7879330Antibodies against type A botulinum neurotoxin
Antibodies for binding epitopes of BoNT/A and hybridomas which produce such antibodies are described. The antibodies of the present invention can be used in a method for detecting BoNT/A in a sample and/or in a method for purifying BoNT/A from an impure solution. In...
02/01/2011
7879020Decision-assist method for resuscitation of patients
A method for providing decision-assist to medical staff resuscitating a burn patient includes receiving patient information, calculating an infusion rate, outputting the infusion rate, obtaining a urinary output, calculating a new infusion rate using infusion rate m...
02/01/2011
7862773Purification apparatus
A purification apparatus, kit and method for purifying DNA, RNA, proteins, antigens, antibodies and cells. The apparatus has a wand and a reservoir tube. The wand is made of a cap, a sample collection assembly and an elongated shaft connecting the cap to the sample ...
01/04/2011
7857803Burn patient resuscitation system and method
A method and system for operating a semi-closed loop and/or a closed loop resuscitation of a burn patient in view of patient information and other physiological data gathered as part of the method and/or by the system. The method in at least one embodiment includes ...
12/28/2010
7851775Gear-type drink-o-meter to monitor fluid consumption
An apparatus for monitoring the consumption of fluid by a user, particularly fluids being drank from a container. The apparatus may be used with wide variety of container types. The fluid monitoring unit uses a pair of gears in rotational engagement with each other ...
12/14/2010
7837723Body thermoregulation using skin temperature feedback
A method and apparatus for cooling a human being utilizes skin temperature feedback to control the amount of cooling. When the measured skin temperature reaches a preset high temperature, the human being is cooled until the measured skin temperature reaches a preset...
11/23/2010
7837472Neurocognitive and psychomotor performance assessment and rehabilitation system
A computerized Neuropsychological/NeuroCognitive and Psychomotor Performance Assessment and Rehabilitation system is designed for use on handheld computer systems. Components of the system include an executive program, test modules, interpretive and report modules, ...
11/23/2010
7825154Small molecule inhibitors of botulinum neurotoxins
Disclosed herein are methods of inhibiting the activity of Botulinum neurotoxin A metalloprotease with the compounds disclosed herein. Also disclosed are methods of treating, inhibiting or preventing intoxication caused by bacteria of at least one bacterial strain i...
11/02/2010
7824864Detection of human antibodies to squalene in serum
The invention is a method and assay for detecting human squalene antibodies in sera or plasma using a blocking agent of −0.5% casein in a phosphate buffered saline (PBS) solution. ...
11/02/2010
7799536Endothelial-monocyte activating polypeptide II, a biomarker for use in diagnosis of brain injury
A diagnostic tool and method of diagnosing brain injury and brain injury type (traumatic vs. ischemic) by detecting the level of expression of endothelial monocyte-activating polypeptide II (EMAP-II) and comparing to a control. An increase of EMAP-II indicates the p...
09/21/2010
7795015Antibodies expressed in insect cells
Three vectors are described which allow the conversion of Fab fragments into or single chain Fv fragments into full-length antibody molecules. Methods for using the vectors and the resulting antibodies are also described. ...
09/14/2010
7790186hybrid circumsporozoite protein and vaccine
Described in this application is a synthetic P. vivax circumsporozoite protein useful as a diagnostic reagent, for antibody production, and as a vaccine protective against infection with any strain of P. vivax. ...
09/07/2010
7790182Protein vaccines against poxviruses
The invention described here entails a protein vaccine against poxviruses which contains at least two purified recombinant monkeypox virus proteins or peptides. The proteins or peptides are encoded by the open reading frames of the monkeypox ortholog genes M1R, A35R...
09/07/2010
7790181Live attenuated viral vaccines for Eastern Equine Encephalitis virus
Live attenuated Eastern Equine Encephalitis (EEE) vaccines that outperform the PE-6 vaccine in mice aerosol challenged with >1,000×LD50. Candidates include four furin-cleavage deletion mutants and one E3 deletion mutant. Each vaccine provided protection in birds ag...
09/07/2010
7786285Recombinant vaccine against botulinum neurotoxin
This invention is directed to preparation and expression of synthetic genes encoding polypeptides containing protective epitopes of botulinum neurotoxin (BoNT). The invention is also directed to production of immunogenic peptides encoded by the synthetic genes, as w...
08/31/2010
7781186Screening methods using normal human liver cell line
In this application is described the establishment and maintenance of a normal human hepatocyte cell line able to support complete development of malaria parasite development in vitro. The cell line can be used in methods for screening compounds affecting normal hum...
08/24/2010
7781183Inhibition of anthrax lethal factor protease
Disclosed herein is a pharmacophore model for inhibiting anthrax lethal factor protease activity which comprises a first aromatic center A, a second aromatic center B, a first polar center C, a second polar center D, a third polar center E, and a neutral linker F. A...
08/24/2010
7780966Artificial invaplex
An artificial invasin complex is prepared from purified or recombinantly prepared invasins and gram negative bacteria lipopolysaccharides. Typically, IpaB is mixed with IpaC to form a IpaB:IpaC complex. This invasin protein complex is then mixed with the lipopolysac...
08/24/2010
7779359Multifunction display design tool
A method that includes but is not limited to accepting user input specifying a geometrical arrangement of two or more buttons on one or more displayed pages; accepting user input labeling at least two of the two or more buttons on the one or more displayed pages; ac...
08/17/2010
7779025System and method for evaluating data sets over a communications network
The present invention is directed to a system and method for providing researchers with a computer-assisted tool to evaluate, over a communications network, large electronic data sets stored on a remote server. The system allows the centralization of multiple data m...
08/17/2010
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