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| Number | Title | Issue Date |
| 6774283 | Molecular farming Novel constructs are provided for expression of physiologically active mammalian proteins in plant cells, either in culture or under cultivation. The constructs provide a promoter functional in a plant host, a structural gene coding for mammalian protein and a termi... | 08/10/2004 |
| 6723530 | Polynucleotides encoding proexendin, and methods and uses thereof Exendin 4 is a biologically active peptide first isolated from Gila monster venom. The invention encompasses polynucleotides encoding proexendin peptides, including exendin and novel peptides, as well as isolated or recombinant proexendin peptides. The invention als... | 04/20/2004 |
| 6706950 | Nucleic acid sequences encoding β-ketoacyl-ACP synthase and uses thereof This invention relates to sequences encoding β-ketoacyl-ACP synthase (KAS) and methods of use thereof. Also provided are methods for decreasing saturated fatty acid levels as a component of total triglycerides found in plant oils. The method generally comprises gro... | 03/16/2004 |
| 6706689 | Treatment of acute coronary syndrome with GLP-1 The invention relates to methods for treating a patient suffering from acute coronary syndrome, but who is not suffering from a Q-wave myocardial infarction, comprising administration of a therapeutically effective amount of a GLP-1 molecule. The GLP-1 can be self-a... | 03/16/2004 |
| 6703359 | Inotropic and diuretic effects of exendin and GLP-1 Methods for increasing urine flow are disclosed, comprising administration of an effective amount of GLP-1, an exendin, or an exendin or GLP-1 agonist. Methods for increasing urinary sodium excretion and decreasing urinary potassium concentration are also... | 03/09/2004 |
| 6699492 | Quinolone carboxylic acid compositions and related methods of treatment The present invention relates to the use of quinolone carboxylic acid formulations in the treatment of ocular and periocular infections. The present invention also relates to sustained release compositions comprising specific quinolone carboxylic acid com... | 03/02/2004 |
| 6693175 | Method for diagnosing bone dysbolism A method of diagnosing metabolic bone diseases, especially osteoporosis and arthrosis characterized by determining the concentration of osteoclastgenesis inhibitory factor (OCIF) in humor. Monoclonal antibodies recognizing equally both of monomer type and dime... | 02/17/2004 |
| 6692170 | Method and apparatus for text input An apparatus for text input and a method for its use. The apparatus includes a display device, a computing device, and an input device. The computer device is configured to generate a character or plurality of characters and to cause the display device to... | 02/17/2004 |
| 6685958 | Quinolone carboxylic acid compositions and related methods of treatment The present invention relates to the use of quinolone carboxylic acid formulations in the treatment of ocular and periocular infections. The present invention also relates to sustained release compositions comprising specific quinolone carboxylic acid com... | 02/03/2004 |
| 6653530 | Methods for producing carotenoid compounds, tocopherol compounds, and specialty oils in plant seeds Methods are provided for producing plants and seeds having altered carotenoid, fatty acid and tocopherol compositions. The methods find particular use in increasing the carotenoid and tocopherol levels in oilseed plants, and in providing desirable high ol... | 11/25/2003 |
| 6596538 | Fatty acyl-CoA: fatty alcohol acyltransferases By this invention, nucleic acid sequences encoding for fatty acyl-CoA: fatty alcohol acyltransferase (wax synthase) are provided, wherein said wax synthase is active in the formation of a wax ester from fatty alcohol and fatty acyl-CoA substrates. Of spec... | 07/22/2003 |
| 6594587 | Method for analyzing biological elements The present invention is in the field of bioinformatics, particularly as it pertains to determining the associations of biological elements. More specifically, the present invention relates to the determination of associations among a set of biological el... | 07/15/2003 |
| 6541259 | Nucleic acid sequences to proteins involved in isoprenoid synthesis Nucleic acid sequences and methods are provided for producing plants and seeds having altered tocopherol content and compositions. The methods find particular use in increasing the tocopherol levels in plants, and in providing desirable tocopherol composi... | 04/01/2003 |
| 6528623 | Antibodies that specifically bind ACT-4-L-h-1 ligand The invention provides ligands and fragments thereof to a receptor on the surface of activated CD4+ T-cells. An exemplary ligand is designated ACT-4-L-h-1. Preferred fragments include purified extracellular domains of ligands. The invention als... | 03/04/2003 |
| 6528055 | Methods of administering antibodies that specifically bind ACT-4-L-h-1 ligand The invention provides ligands and fragments thereof to a receptor on the surface of activated CD4+ T-cells. An exemplary ligand is designated ACT-4-L-h-1. Preferred fragments include purified extracellular domains of ligands. The invention als... | 03/04/2003 |
| 6518488 | Nucleic acid molecules and other molecules associated with the ଲ-oxidation pathway The present invention is in the field of plant biochemistry, particularly as it pertains to the ଲ-oxidation pathway. More specifically, the invention relates to nucleic acid molecules that encode proteins and fragments of proteins associated with th... | 02/11/2003 |
| 6500114 | Method of extracting biopsy cells from the breast A method of extracting biopsy cells from a breast uses an endoscopic instrument having a distal end that is substantially needle like, a working channel, a light source and a lens. The instrument can be coupled to an apparatus for viewing an image includi... | 12/31/2002 |
| 6476294 | Plant phosphatidic acid phosphatases By this invention, novel nucleic acid sequences encoding for phosphatidic acid phosphatase (PAP) proteins are provided, wherein said PAP protein is active in the formation of diacylglycerol from phosphatidic acid. Also considered are amino acid and nuclei... | 11/05/2002 |
| 6475724 | Nucleic acids, kits, and methods for the diagnosis, prognosis and treatment of glaucoma and related disorders In a preferred aspect of the invention, the upstream sequences of the TIGR protein encoding sequence can be used to diagnose a sensivity to steroids and a risk for glaucoma or ocular hypertensive disorders. Methods, kits, and nucleic acids containing poly... | 11/05/2002 |
| 6444876 | Acyl CoA: cholesterol acyltransferase related nucleic acid sequences By this invention, novel nucleic acid sequences encoding for acyl-CoA: cholesterol acyltransferase (ACAT) related proteins are provided, wherein ACAT-like protein is active in the formation of a sterol ester and/or triacylylgycerol from a fatty acyl-CoA a... | 09/03/2002 |
| 6429356 | Methods for producing carotenoid compounds, and specialty oils in plant seeds Methods are provided for producing plants and seeds having altered carotenoid, fatty acid and tocopherol compositions. The methods find particular use in increasing the carotenoid levels in oilseed plants and in providing desirable high oleic acid seed oi... | 08/06/2002 |
| 6397849 | Methods of ophthalmic administration Intrascleral injection of a therapeutic or diagnostic material at a location overlying the retina provides a minimally invasive technique for delivering the agent to the posterior segment of the eye. The procedure also allows for close proximity of the ma... | 06/04/2002 |
| 6380466 | Production of improved rapeseed exhibiting yellow-seed coat Rapeseed in plants producing rapeseed which have a yellow-seed coat are provided. The yellow-seed coat is controlled by a single locus mutation. Plants from the rapeseed are useful for transferring the trait into elite lines of canola.... | 04/30/2002 |
| 6380462 | Method for increasing stearate content in soybean oil This invention relates to a method for increasing stearate as a component of total triglycerides found in soybean seed. The method generally comprises growing a soybean plant having integrated into its genome a DNA construct comprising, in the 5' to 3' di... | 04/30/2002 |
| 6378526 | Methods of ophthalmic administration Intrascleral injection of a therapeutic or diagnostic material at a location overlying the retina provides a minimally invasive technique for delivering the agent to the posterior segment of the eye. The procedure also allows for close proximity of the ma... | 04/30/2002 |
| 6372245 | Plasticized bioerodible controlled delivery system A controlled release medicament delivery system comprises a plasticized bioerodible polymer, such as a polyorthoester. Medicament desirably is entrapped in the plasticized polymer. The resulting delivery system is able to release the medicament in a contr... | 04/16/2002 |
| 6365802 | Methods for increasing stearate content in soybean oil This invention relates to a method for increasing stearate as a component of total triglycerides found in soybean seed. The method generally comprises growing a soybean plant having integrated into its genome a DNA construct comprising, in the 5' to 3' di... | 04/02/2002 |
| 6309630 | Non-steroidal anti-inflammatory ophthalmic suspensions Compositions for topical ophthalmic application comprising an aqueous mixture of a non-steroidal anti-inflammatory agent. The compositions are formulated with a pH and concentration of agent chosen to maintain at least some of the therapeutic agent of the... | 10/30/2001 |
| 6309374 | Injection apparatus and method of using same The present invention relates to an apparatus and method for using the apparatus for injecting an agent into a tissue, particularly into thin tissues such as the sclera of the eye. The invention provides an apparatus and method for effectively imbedding a... | 10/30/2001 |
| 6299603 | Injection apparatus and method of using same The present invention relates to an apparatus and method for using the apparatus for injecting an agent into a tissue, particularly into thin tissues such as the sclera of the eye. The invention provides an apparatus and method for effectively imbedding a... | 10/09/2001 |
| 6277962 | Receptor on the surface of activated t-cells: act-4 The invention provides purified ACT-4 receptor polypeptides, antibodies against these polypeptides and nucleic acids encoding ACT-4 receptor polypeptides. Also provided are methods of diagnosis and treatment using the same. ACT-4 receptors are preferentia... | 08/21/2001 |
| 6265444 | Ophthalmic composition An ophthalmic composition containing a divalent salt and a non-steroidal anti-inflammatory agent as a precipitate. The composition reduces or eliminates the risk of stinging and burning the eye from topical application. Additionally a preservative system ... | 07/24/2001 |
| 6242566 | Ligand (ACT-4-L) to a receptor on the surface of activated CD4+ T-cells The invention provides ligands and fragments thereof to a receptor on the surface of activated CD4+ T-cells. An exemplary ligand is designated ACT-4-L-h-1. Preferred fragments include purified extracellular domains of ligands. The invention als... | 06/05/2001 |
