Did You Know...
...that the Band-Aid Bandage was invented by a Johnson & Johnson employee whose wife had cut herself? Earl Dickson's wife was rather accident prone, so he set out to develop a bandage that she could apply without help. He placed a small piece of gauze in the center of a small piece of surgical tape, and what we know today as the Band Aid bandage was born!
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| Number | Title | Issue Date |
| 7449463 | Morpholinyl containing benzimidazoles as inhibitors of respiratory syncytial virus replication The present invention concerns morpholinyl containing benzimidazoles having inhibitory activity on the replication of the respiratory syncytial virus and having the formula a prodrug, N-oxide, addition salt, quaternary amin... | 11/11/2008 |
| 7385066 | Thiophene sulfoximines, compositions thereof, and methods of treating complement-mediated diseases and conditions Disclosed are compounds for treating the symptoms of an acute or chronic disorder mediated by the classical pathway of the complement cascade. The compounds are of Formula I or a solvate, hydrate, pharmaceutically acceptabl... | 06/10/2008 |
| 7297691 | Treatment of sleep disorders with cholinesterase inhibitors The present invention is concerned with treatment of sleep disorders by administering a cholinesterase inhibitor, and in particular, by administering galantamine or a pharmaceutically acceptable salt thereof. Also in particular, cholinesterase inhibitors that are ac... | 11/20/2007 |
| 7196209 | Continuous process for the preparation of fructopyranose sulfamate derivatives The present invention is directed to a continuous process for the preparation of fructopyranose sulfamate derivatives of the general formula (I) wherein R1, R3, R | 03/27/2007 |
| 7153837 | Agent for protection of retinal neurons This invention relates to an agent for the protection of retinal neurons which comprises, as an effective ingredient, sulfamate derivative having the following formula: and to a method for the protection of retin... | 12/26/2006 |
| 7125560 | Pharmaceutical composition of topiramate The invention is directed to a pharmaceutical composition of topiramate, an anticonvulsant which is useful for treating epilepsy. More specifically, the present invention provides a solid dosage formulation of topiramate intended primarily for use by pediatric patie... | 10/24/2006 |
| 7060725 | Substituted sulfamate anticonvulsant derivatives The present invention is directed to novel compounds of the formula (I) wherein X, R1, R2, R3, R4, R5 and R6 are as descr... | 06/13/2006 |
| 7049331 | 1,2,4-thiadiazole derivatives as melanocortin receptor modulators The present invention is directed to novel 1,2,4-thiadiazole derivatives useful as agonists or antagonists of the melanocortin receptor. More particularly, the compounds of the present invention are useful for the treatment of metabolic, CNS and dermatological disor... | 05/23/2006 |
| 7041650 | Anticonvulsant derivative salts The invention relates to novel pharmaceutically acceptable salts of anticonvulsant derivatives, processes for preparation of and pharmaceutical compositions containing said salts, useful in the treatment of epilepsy. ... | 05/09/2006 |
| 6696091 | Pharmaceutical composition of topiramate The invention is directed to a pharmaceutical composition of topiramate an anticonvulsant which is useful for treating epilepsy. More specifically, the present invention provides a solid dosage formulation of topiramate intended primarily for use by pedia... | 02/24/2004 |
| 6667060 | Pregelatinized starch in a controlled release formulation The present invention concerns the use of pregelatinized starch to prevent dose-dumping from a hydrophilic controlled release formulation. It also concerns a hydrophilic controlled release formulation, more in particular a hydrophilic controlled release m... | 12/23/2003 |
| 6555544 | Aqueous suspensions of submicron 9-hydroxyrisperidone fatty acid esters The present invention is concerned with a pharmaceutical composition suitable as a depot formulation for administration via intramuscular or subcutaneous injection, comprising: (1) as an active ingredient a therapeutically effective amount of a 9-hydroxy-... | 04/29/2003 |
| 6531478 | Amino pyrazole derivatives useful for the treatment of obesity and other disorders Amino pyrazole derivatives of the formula: ##STR1## which are ligands for the neuropeptide Y, subtype 5 receptor and pharmaceutical compositions containing an amino pyrazole derivative as the active ingredient are described. The amino pyrazole derivatives... | 03/11/2003 |
| 6521621 | 1-(1,2-disubstituted piperidinyl)-4-substituted piperazine derivatives This invention concerns the compounds of formula ##STR1## the N-oxide forms, the pharmaceutically acceptable addition salts and the stereoisomeric forms thereof, wherein n is 0, 1 or 2; m is 1 or 2, provided that if m is 2, then n is 1; p is 1 or 2; .dbd.... | 02/18/2003 |
| 6511976 | Halogen substituted tetracyclic tetrahydrofuran derivatives This invention concerns the compounds of formula (I), ##STR1## the N-oxide forms, the pharmaceutically acceptable addition salts and the stereochemically isomeric forms thereof, wherein n is zero, 1, 2, 3, 4, 5 or 6; X is CH2 or O; R1 | 01/28/2003 |
| 6506768 | Tetrahydro γ-carbolines The present invention concerns the compounds of formula ##STR1## the N-oxide forms, the pharmaceutically acceptable addition salts and the stereochemically isomeric forms thereof, wherein R1 is hydrogen, optionally substituted C1-6 a... | 01/14/2003 |
| 6420369 | Anticonvulsant derivatives useful in treating dementia Anticonvulsant derivatives useful in treating dementia and/or behavioral and psychotic disturbances in dementia are disclosed.... | 07/16/2002 |
| 6407136 | 1,4-dithiin and 1,4-dithiepin-1,1,4,4, tetroxide derivatives useful as antagonists of the human galanin receptor The invention is directed to 1,4-dithiin- and 1,4-dithiepin-1,1,4,4-tetroxide derivatives useful as galanin receptor antagonists for treating disorders of the central nervous system. Pharmaceutical compositions comprising the compounds of the present ... | 06/18/2002 |
| 6403805 | 1,3-dihydro-1-(phenylalkyl)-2H-imidazol-2-one derivatves The present invention describes compounds useful for treating warm-blooded animals suffering from disease states related to an abnormal enzymatic or catalytic activity of phosphodiesterase IV (PDE IV), and/or disease states related to a physiologically de... | 06/11/2002 |
| 6372729 | Trisubstituted 1,3,5,-triazine derivatives This invention concerns the use of the compounds of formula ##STR1## the N-oxides, the pharmaceutically acceptable addition salts and the stereochemically isomeric forms thereof, wherein A is CH, CR4 or N; n is 0, 1, 2, 3 or 4; R1 an... | 04/16/2002 |
| 6358946 | C-6 ring-substituted pyrido[1,2-a]benzimidazole derivatives useful in treating central nervous system disorders A C-6 ring-substituted pyrido[1,2-a]benzimidazole derivative of the formula: ##STR1## methods of preparation and pharmaceutical compositions containing a substituted pyrido[1,2-a]benzimidzole derivative as the active ingredient are disclosed. The sub... | 03/19/2002 |
| 6346518 | Itraconazole and saperconazole stereoisomers The present invention is concerned with the stereoisomeric forms of itraconazole (X=Cl) and saperconazole (X=F), which may be represented by the formula ##STR1## and the pharmaceutically acceptable acid addition salt forms thereof, processes for prep... | 02/12/2002 |
| 6346540 | 1-(1,2-disubstituted pipeidinyl)-4-substituted piperidine derivatives The present invention concerns compounds of formula ##STR1## the N-oxide forms, the pharmaceutically acceptable addition salts and stereochemically isomeric forms thereof, wherein n is 0, 1 or 2; m is 1 or 2, provided that if m is 2, then n is 1; p is 0, ... | 02/12/2002 |
| 6323219 | Methods for treating immunomediated inflammatory disorders This invention relates to methods ands compositions for bringing about changes in skin pigmentation and for treating inflammatory disorders. More particularly, this invention relates to compounds which affect melanogenesis and can be used as depigmenting ... | 11/27/2001 |
| 6319939 | Retinoic acid mimetic anlides The present invention is concerned with compounds of formula ##STR1## the N-oxides, the pharmaceutically acceptable addition salts and the stereochemically isomeric forms thereof, wherein X represents O, S or NR3 ; R1 represents hydr... | 11/20/2001 |
| 6319903 | Anticonvulsant derivatives useful in treating cluster headaches Anticonvulsant derivatives useful in treating cluster headaches are disclosed.... | 11/20/2001 |
| 6303147 | Bioadhesive solid dosage form The present invention is concerned with bioadhesive pharmaceutical compositions comprising a pharmaceutically effective amount of an active ingredient, from 80% to 98.8% (w/w/) pre-gelatinized starch, and from 1% to 10% (w/w) of a hydrophilic matrix formi... | 10/16/2001 |
| 6303614 | Tetrahydro gamma-carbolines The present invention concerns the compounds of formula ##STR1## the N-oxide forms, the pharmaceutically acceptable addition salts and the stereochemically isomeric forms thereof, wherein R1 is hydrogen, optionally substituted C1-6 a... | 10/16/2001 |
| 6291476 | Pyrazole carboxamides useful for the treatment of obesity and other disorders Pyrazole carboxamide derivatives of the formula: ##STR1## which are ligands for the neuropeptide Y, subtype 5 receptor, and pharmaceutical compositions containing a pyrazole carboxamide derivative as the active ingredient are described. The pyrazole carbo... | 09/18/2001 |
| 6288058 | Substituted tetracyclic tetrahydrofuran derivatives This invention concerns the compounds of formula (I), ##STR1## the N-oxide forms, the pharmaceutically acceptable addition salts and the stereoisomeric forms thereof, wherein n is zero to 6; p and q are zero to 4; r is zero to 5; R1 and R2... | 09/11/2001 |
| 6265425 | Combination of a RAMBA and a tocopherol The present invention is concerned with the use of a tocopherol for the manufacture of a medicament for avoiding, alleviating, suppressing or overcoming the adverse side-effects of therapy with a retinoic acid metabolism blocking agent. The present invent... | 07/24/2001 |
| 6262052 | Amino acid ester containing azole antifungals The present invention concerns novel compounds of formula ##STR1## the N-oxide forms, the pharmaceutically acceptable addition salts thereof and stereochemically isomeric forms thereof, wherein --A--B-- forms a bivalent radical of formula --N.dbd.CH-- (a)... | 07/17/2001 |
| 6251894 | 1-(1,2-disubstituted piperidinyl)-4 (fused imidazole)-piperidine derivatives This invention concerns the compounds of formula ##STR1## the N-oxide forms, the pharmaceutically acceptable addition salts and the stereochemically isomeric forms thereof, wherein n is 0, 1 or 2; m is 1 or 2, provided that if m is 2, then n is 1; .dbd.Q ... | 06/26/2001 |
| 6224849 | Alkylaminobenzothiazole and-benzoxazole derivatives The present invention concerns the compounds of formula ##STR1## the N-oxide forms, the pharmaceutically acceptable acid addition salts and stereochemically isomeric forms thereof, wherein X is O or S; n is 2, 3, 4 or 5; R1 is hydrogen, C1... | 05/01/2001 |
| 6197779 | HIV inhibiting pyrimidine derivative This invention concerns the use of the compounds of formula ##STR1## the N-oxides, the pharmaceutically acceptable addition salts and the stereochemically isomeric forms thereof, wherein A is CH, CR4 or N; n is 0 to 4; Q is hydrogen or --NR | 03/06/2001 |
| 6197772 | 1- (1,2-disubstituted piperidinyl) -4-substituted piperazine derivatives This invention concerns the compounds of formula ##STR1## the N-oxide forms, the pharmaceutically acceptable addition salts and the stereoisomeric forms thereof, as substance-P antagonists; their preparation, compositions containing them and their use as ... | 03/06/2001 |
| 6194405 | Method of using substituted tetracyclic tetrahydrofuran derivatives This invention concerns the compounds of formula (I), ##STR1## the N-oxide forms, the pharmaceutically acceptable addition salts and the stereoisomeric forms thereof, wherein n is zero to 6; p and q are zero to 4; r is zero to 5; R1 and R2... | 02/27/2001 |
| 6169097 | 1-(1,2-Disubstituted piperidinyl)-4-substituted piperidine derivatives The present invention concerns compounds of formula ##STR1## the N-oxide forms, the pharmaceutically acceptable addition salts and stereochemically isomeric forms thereof, wherein n is 0, 1 or 2; m is 1 or 2, provided that if m is 2, then n is 1; p is 0, ... | 01/02/2001 |
| 6159982 | 2,4-diaminopyrimidine derivates as dopamine D4 receptor antagonist The present invention concerns the compounds of formula ##STR1## the N-oxide forms, the pharmaceutically acceptable acid addition salts and stereochemically isomeric forms thereof, wherein Alk is C1-6 alkanediyl or C3-6 alkenedi... | 12/12/2000 |
| 6156747 | Isoxazolidine derivatives This invention concerns the compounds of formula (I), ##STR1## the N-oxide forms, the pharmaceutically acceptable addition salts and the stereochemically isomeric forms thereof, wherein n is zero to 6; p is zero to 3; q is zero to 3; r is zero to 3; ... | 12/05/2000 |
