Did You Know...
...that several people are credited with the invention of the flush toilet? Most people have heard of Thomas Crapper (1837-1910), the sanitary engineer who invented the valve-and-siphon arrangement that made the modern toilet possible. Another claimant to "the throne" was British inventor Alexander Cumming who patented a toilet in 1775. Then there's a nameless Minoan (a native of ancient Crete) who lived 4,000 years ago who supposedly was ahead of his time and created the first flush toilet!
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| Number | Title | Issue Date |
| 4396616 | Substituted enantholactam derivatives as antihypertensives Substituted enantholactam dipeptides and derivatives thereof are disclosed which are useful as converting enzyme inhibitors and as antihypertensives.... | 08/02/1983 |
| 4366096 | Cellulosic urea formaldehyde compositions Non-flammable reactive particle compositions useful in forming shaped articles prepared from flammable cellulosic materials and a type of urea/formaldehyde resin. Processes for their preparation and a method of rendering flammable reactive particles subst... | 12/28/1982 |
| 4358455 | Aralkylamindethanol heterocyclic compounds Heterocyclic aminoethanols of the formula where het is a 6-10 membered N heterocycle are disclosed. The compounds are useful as pharmaceuticals.... | 11/09/1982 |
| 4294969 | Process for producing 2-bromo-3,5-disubstituted pyridines Novel substituted (3-loweralkylamino-2-R1 O-propoxy)pyridines, their pharmaceutically acceptable salts, certain intermediates and their preparation are disclosed. These pyridines have pharmaceutically useful properties such as ଲ-adrenergi... | 10/13/1981 |
| 4237160 | 3-Hydroxymethyldibenzo[b,f]thiepins as prostaglandin antagonists Novel 3-hydroxymethyldibenzo[b,f]thiepin and derivatives are prepared and employed in the treatment and control of allergic conditions such as allergic asthma.... | 12/02/1980 |
| 4233457 | Process for preparing indenyl acetic acids This invention relates to an improved process for preparing 5-fluoro-2-methyl-1-(p-methylsulfinylbenzylidene)-3-indenyl acetic acid.... | 11/11/1980 |
| 4230105 | Transdermal delivery of drugs An improved method for the topical administration of systemically or locally active drugs utilizes a bandage containing one or more layers including a drug useful in the treatment of disease and a heat-generating substance, each dispersed intimately throu... | 10/28/1980 |
| 4225609 | Interphenylene 9-thia-11-oxo-12-aza-prostanoic acids This invention relates to novel interphenylene 9-thia-11-oxo-12-azaprostanoic acid compounds, salts, and derivatives thereof. These compounds are exceptionally potent renal vasodilators and antihypertensives which are active when administered orally but w... | 09/30/1980 |
| 4223788 | Reclosable thermoformed blister-type package A rigid blister package includes a rigid thermoformed plastic cover piece and a flexible backing sheet, a score line for opening said package, and a slide fastener for reclosing the blister package, along with stops to hold the slide fastener in the open ... | 09/23/1980 |
| 4217429 | Poly-[(methylimino)trimethylene] Novel polymers having a linear backbone which is free from both branching and cross-linking, comprising quaternized nitrogen atoms linked to each other through trimethylene groups. By the term "linear backbone" is meant that the polymer has only acyclic g... | 08/12/1980 |
| 4207323 | 6-Substituted methyl penicillins, derivatives and analogues thereof Disclosed are antibiotic 6-(substituted methyl) penicillins, derivatives and nuclear analogues thereof; wherein the methyl substituent is, inter alia, hydroxyl, ketonic oxygen, imino nitrogen, amino or thio. Also disclosed are processes for the preparatio... | 06/10/1980 |
| 4201771 | Antibiotic A43F The antibiotic A43F is active against a variety of plant pathogenic fungi. The antibiotic A43F is produced by growing an as yet unclassified species of fungus (ATCC No. 20529) on suitable fermentation media and isolating the bioactive component therefrom.... | 05/06/1980 |
| 4194424 | Apparatus for longitudinal slicing of cylindrical body This invention relates to an apparatus for slicing cylindrically shaped columns of gels. More particularly, it relates to an apparatus for firmly holding cylindrical columns of acrylamide gel while making a longitudinal slice through the entire length of ... | 03/25/1980 |
| 4187284 | Skeletal imaging kit utilizing triethylene tetramine hexa (methylene phosphonic acid) This invention relates to a novel diagnostic kit for use in radiographic bone scanning. More particularly, it relates to a kit comprising ingredients employed in the preparation of an intravenous injection of a complex of Technetium-99m, stannous ion, and... | 02/05/1980 |
| 4185088 | Non-adhesive ionene quaternary polymer compositions useful as bile acid sequestrants The invention disclosed herein relates to novel non-adhesive, free-flowing, pharmacologically acceptable compositions comprising ionene quaternary polymers effective as bile acid sequestrants, such as poly-[{methyl-(3-trimethylammoniopropyl)iminio}trimeth... | 01/22/1980 |
| 4175203 | Interphenylene 11,12-secoprostaglandins Novel interphenylene derivatives of 11,12-secoprostaglandins are prepared by the stepwise alkylation of the ethyl ester or the t-butyl ester of acetoacetic acid. One such method involves treatment of the t-butyl ester of acetoacetic acid with a strong bas... | 11/20/1979 |
| 4155908 | 9-Thia- and oxothia- and 9-dioxothia-11,12-seco-prostaglandins This invention relates to 9-thia- , 9-oxothia, and 9-dioxothia-11,12-seco-prostaglandins and processes for their manufacture. These compounds have prostaglandin-like biological activity and are particularly useful for the treatment of skin diseases such a... | 05/22/1979 |
| 4150235 | Interphenylene 11,12-secoprostaglandins Novel interphenylene derivatives of 11,12-secoprostaglandins are prepared by the stepwise alkylation of the ethyl ester or the t-butyl ester of acetoacetic acid. One such method involves treatment of the t-butyl ester of acetoacetic acid with a strong bas... | 04/17/1979 |
| 4140861 | Interphenylene 11,12-secoprostaglandins Novel interphenylene derivatives of 11,12-secoprostaglandins are prepared by the stepwise alkylation of the ethyl ester or the t-butyl ester of acetoacetic acid. One such method involves treatment of the t-butyl ester of acetoacetic acid with a strong bas... | 02/20/1979 |
| 4128564 | 9-Thia- and oxothia- and 9-dioxothia-11,12-seco-prostaglandins This invention relates to 9-thia-, 9-oxothia, and 9-dioxothia-11,12-seco-prostaglandins and processes for their manufacture. These compounds have prostaglandin-like biological activity and are particularly useful for the treatment of skin diseases such as... | 12/05/1978 |
| 4127584 | 2,3-Substituted-1,2,5-thiadiazolium salt antimicrobials 2-R1 -Substituted-3-amino-R2 -substituted-1,2,5-thiadiazolium salts have broad spectrum antibacterial and antifungal activity. They are useful for cleansing inanimate surfaces as well as agents for agriculture.... | 11/28/1978 |
| 4126629 | Substituted phenoxy-tridecenoic acids/esters This invention relates to aryloxy-, alkoxy-, arylthio-, and alkylthio-11,12-seco-prostaglandins and to processes for their manufacture. These compounds have prostaglandin-like activity and are particularly useful in fertility control such as for estrus ... | 11/21/1978 |
| 4112236 | Interphenylene 8-aza-9-dioxothia-11,12-secoprostaglandins Interphenylene 8-aza-9-dioxothia-11,12-secoprostaglandins are prepared by the two-stage alkylation of the anion of a lower alkyl sulfonamide, R1 SO2 NH2, using first a compound of the formula: ##STR1## and second, a c... | 09/05/1978 |
| 4107072 | Process of isolating cyclohexane-free ethylcellulose microcapsules Ethylcellulose walled microcapsules, obtained from cyclohexane medium are heavily solvated with cyclohexane and tend to form lumps even after drying. Displacements of cyclohexane by pentane, hexane, heptane or octane or mixtures thereof during the isolati... | 08/15/1978 |
| 4102888 | 3-Thiazolidinyl heptanoic acids This invention relates to novel 8-aza-9-oxo-11-thia-, -11-oxothia-, and -11-dioxothia-prostanoic acid compounds, salts, and derivatives thereof and also to processes for the preparation of such compounds. These compounds have prostaglandin-like biological... | 07/25/1978 |
| 4098726 | Poly[{alkyl-(3-ammoniopropyl)iminio}trimethylene dihalides] and process Novel polymers having a linear backbone which is free from both branching and cross-linking, comprising quaternized nitrogen atoms linked to each other through trimethylene groups. By the term "linear backbone" is meant that the polymer has only acyclic g... | 07/04/1978 |
| 4097504 | 11,12-Secoprostaglandins This invention relates to 11,12-secoprostaglandins and processes for their manufacture. These compounds have prostaglandin-like biological activity and are particularly useful as renal vasodilators, for the treatment of hypertension, for the prevention of... | 06/27/1978 |
| 4091107 | 8-Aza-9-oxo(and dioxo)-thia-11,12-secoprostaglandins This invention relates to 8-aza-9-ozo(and dioxo)-thia-11,12-secoprostaglandins and processes for their manufacture. These compounds have prostaglandin-like biological activity and are particularly useful as renal vasodilators, for the prevention of thromb... | 05/23/1978 |
| 4076939 | 2-(4-Substituted-1,2,5-thiadiazole-3-yloxy)-acetaldehydes Novel 2-(4-substituted-1,2,5-thiadiazol-3-yloxy)acetaldehydes are disclosed. These acetaldehydes are useful as intermediates for preparing certain ଲ-adrenergic blocking agents.... | 02/28/1978 |
| 4071570 | Arylperfluoroalkanes New fluoro derivatives of aralkylamine compounds, particularly 2-(2-phenyl-1,1,2,2-tetrafluoroethyl)benzylamine, as well as the N-alkyl and the N,N-dialkyl derivatives thereof are prepared by reaction of 2-bromobenzonitrile with benzylmagnesium chloride t... | 01/31/1978 |
| 4070493 | Diagnostic kit This invention relates to a colloid-forming composition useful in medical diagnosis. More particularly, it relates to an improved kit useful as a diagnostic aid comprising colloid-forming reagent solutions. It further relates to a kit useful in medical diagnos... | 01/24/1978 |
| 4070478 | Benzimidazole substituted alanines Benzimidazol-5-yl alanine derivatives useful as antihypertensive agents are disclosed as well as methods for their preparation.... | 01/24/1978 |
| 4066675 | 9-Thia- and oxothia- and 9-dioxothia-11,12-seco-prostaglandins and processes This invention relates to 9-thia-, 9-oxothia, and 9-dioxothia-11,12-seco-prostaglandins and processes for their manufacture. These compounds have prostaglandin-like biological activity and are particularly useful for the treatment of skin diseases such as... | 01/03/1978 |
| 4066692 | 11,12-Secoprostaglandins This invention relates to 11,12-secoprostaglandins and processes for their manufacture. These compounds have prostaglandin-like biological activity and are particularly useful as renal vasodilators, for the treatment of hypertension, for the prevention of... | 01/03/1978 |
| 4061643 | Certain 16-aryloxy-11,12-seco-prostaglandins This invention relates to aryloxy-, alkoxy-, arylthio-, and alkylthio-11,12-seco-prostaglandins and to processes for their manufacture. These compounds have prostaglandin-like activity and are particularly useful in fertility control such as for estrus ... | 12/06/1977 |
| 4060601 | Certain lower-alkyl amino-2'-hydroxy-propoxy pyridines Novel substituted (3-loweralkylamino-2-R1 O-propoxy)pyridines, their pharmaceutically acceptable salts and their preparation are disclosed. These pyridines have pharmaceutical properties such as anti-hypertensive activity of rapid onset.... | 11/29/1977 |
| 4059601 | 8-Halo-11,12-secoprostaglandins This invention relates to 11,12-secoprostaglandins and processes for their manufacture. These compounds have prostaglandin-like biological activity and are particularly useful as renal vasodilators, for the treatment of hypertension, and for the preventio... | 11/22/1977 |
| 4059587 | Certain thiazolidine compounds This invention relates to novel 8-aza-9-oxo-11-thia-, -11-oxothia-, and -11-dioxothia-prostanoic acid compounds, salts, and derivatives thereof and also to processes for the preparation of such compounds. These compounds have prostaglandin-like biological... | 11/22/1977 |
| 4055665 | Treating arrythmia with phenylthioaralkylamines Phenylthioaralkylamines and 2-phenylthiobenzylamines are prepared by reaction of the corresponding phenylthiobenzoyl chloride or homologs thereof with ammonia or an amine to produce the corresponding phenylthiobenzamide or N-substituted or N,N-disubstitut... | 10/25/1977 |
| 4055597 | 10-Aza-11,12-secoprostaglandins This invention relates to 10-aza-11,12-secoprostaglandins and processes for their manufacture. These compounds have prostaglandin-like biological activity and are particularly useful as renal vasodilators.... | 10/25/1977 |
