Did You Know...
...that a workman who left the soap mixing machine on too long was responsible for making Ivory Soap? He was so embarrassed by his mistake that he threw the mess in a stream. Imagine his dismay when the evidence of his error floated to the surface! Result: Ivory soap, the soap that floats.
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 5922907 | Precursors of ଲ-lactam antibacterials having soluble side chain esters Disclosed is a process for the synthesis of ଲ-lactam antibacterials using soluble side chain esters in the presence of enzyme acylase. Also disclosed are novel esters useful as reactants in said process.... | 07/13/1999 |
| 5869734 | Preparation of optically active (S)-(-) and (R)-(+)-deoxyspergualin and novel intermediates thereof A process for preparing optically active (S)-(-) and (R)-(+)-deoxyspergualin and salts thereof of the formula I ##STR1## by reacting a compound of formula II ##STR2## with a compound of formula III ##STR3## in the presence of a condens... | 02/09/1999 |
| 5837828 | Pradimicin derivatives The present invention concerns neutral sugar derivatives of pradimicins, their use as antifungal agents, methods for their preparation, and intermediates for their synthesis.... | 11/17/1998 |
| 5837702 | 4-arylamino-benzopyran and related compounds Compounds having the formula ##STR1## and pharmaceutically acceptable salts thereof wherein X is alkyl, Y is a single bond, --CH2 --, --C(O)--, --O--, --S-- or --N(R8)-- where R8 is hydrogen, alkyl, haloalkyl, aryl, a... | 11/17/1998 |
| 5705645 | Hereroaryl derivatives of monocyclic beta-lactam antibiotics Antibacterial activity is exhibited by novel compounds having the formula ##STR1## where R1, R2, and M are as defined herein and X is --(CH2)n -- wherein n is 0, 1, 2, 3 or 4 or CR3 R4 ... | 01/06/1998 |
| 5627192 | Antihyperlipidemic/antioxidant dihydroquinolines The present invention relates to novel dihydroquinolines which are useful for cholesterol lowering and as antioxidant agents. Also provided is a process for preparing the dihydroquinolines of the present invention, pharmaceutical compositions, and a metho... | 05/06/1997 |
| 5411969 | Antihyperlipidemic/antioxidant dihydroquinolines The present invention relates to novel dihydroquinolines which are useful for cholesterol lowering and as antioxidant agents. Also provided is a process for preparing the dihydroquinolines of the present invention, pharmaceutical compositions, and a metho... | 05/02/1995 |
| 5410029 | Pradimicin derivatives The present invention concerns neutral sugar derivatives of pradimicins, their use as antifungal agents, methods for their preparation, and intermediates for their synthesis.... | 04/25/1995 |
| 5391765 | Cholesterol lowering/antioxidant nitroxides The present invention relates to novel nitroxides which are useful for cholesterol lowering and as antioxidant agents. Also provided is a process for preparing the nitroxides of the present invention, pharmaceutical compositions, and a method of treating ... | 02/21/1995 |
| 5380854 | Diphenyl-heterocyclic-oxazole as platelet aggregation inhibitors A novel series of oxazole derivatives having enhanced water solubility bioavailability and metabolic stability is disclosed in the Formula I ##STR1## or pharmaceutically acceptable salt thereof.... | 01/10/1995 |
| 5380713 | Peptide aldehydes as antithrombotic agents This invention relates to novel arginine aldehydes, their salts and hydrates, which compounds selectively exhibit serine proteases inhibitory activity, are highly stable in aqueous solutions, and are useful for anti-trypsin and anti-thrombin activity.... | 01/10/1995 |
| 5362879 | 4-5-diphenyloxazole derivatives as inhibitors of blood platelet aggregation A novel series of oxazole derivatives having the Formulae I and II ##STR1## wherein R is H or C1 -C5 lower alkyl, X is N or CH, Y is H or CO2 R1, or CO.R2, provided that when X is CH, Y is not H, R1 | 11/08/1994 |
| 5348960 | Imidazo[4,5-b]quinolinyl oxy alkyl tetrazolyl piperidine derivatives A series of 1,3-dihydro-2H-imidazo[4,5-b]quinolin-2-ones having enhanced water solubility bioavailability and metabolic stability is disclosed in the Formula I ##STR1## wherein R1 is H, or C1 -C4 lower alkyl; R2 | 09/20/1994 |
| 5348969 | Diphenyloxazolyl-oxazoles as platelet aggregation inhibitors A novel series of oxazole derivatives having enhanced water solubility bioavailability and metabolic stability is disclosed in the Formula I ##STR1## Y is CH3, Ph, or OH, provided that when Y is OH, the compound exists in the keto-enol tau... | 09/20/1994 |
| 5328932 | Bisamidine derivatives as thrombin inhibitors The present invention provides new thrombin inhibiting bisamidines derivatives, their pharmaceutically acceptable salts and hydrates, methods for their preparation, pharmaceutical composition, a process for their preparation, and use of the compounds in t... | 07/12/1994 |
| 5321046 | Hypocholesterolemic unsymmetrical dithiol ketals Disclosed herein are novel unsymmetrical dithiol ketals which are useful in the treatment or prevention of hypercholesterolemia, hyperlipoproteinemia, and atherosclerosis.... | 06/14/1994 |
| 5318989 | Cytotoxic bicyclo [7.3.1.]tridec-4-ene-2,6-diyne compounds and process for the preparation thereof The present invention relates to a novel and efficient process for the preparation of 8-hydroxybicyclo[7.3.1]tridec-4-ene-2,6-diyne ring system which is part of the aglycone of esperemicin and to novel cytotoxic antitumor agents having said bicyclic ring ... | 06/07/1994 |
| 5318993 | Antihyperlipidemic benzoquinones The present invention relates to novel benzoquinones which are useful as antihyperlipidemic agents. The present invention also provides a process for their preparation, pharmaceutical compositions, and a method for treating birds and mammals in need there... | 06/07/1994 |
| 5296508 | Farnesylated tetrahydro-naphthalenols as hypolipidemic agents The invention relates to novel farnesylated tetrahydro-naphthalenols, that inhibit HMGR activity which results in a decrease in serum total cholesterol, a decrease in LDL cholesterol levels, and inhibition of LDL oxidation. The farnesylated tetrahydro-nap... | 03/22/1994 |
| 4447360 | Intermediates for thia-aza compounds with a ଲ-lactam ring 2-Penem-3-carboxylic acid compounds of the formula ##STR1## in which R1 represents hydrogen, an organic radical bonded by a carbon atom to the ring carbon atom or an etherified mercapto group and R2 represents hydroxy or a radical R | 05/08/1984 |
| 4386097 | Benzimidazoles, processes for their preparation and pharmaceutical preparations containing such compounds The invention relates to 2-carboethoxyamino-5(6)-(2-amino-5-thiazoloyl)-benzimidazole compounds with anthelmintic properties and to processes for their preparation and pharmaceutical preparations containing such compounds.... | 05/31/1983 |
| 4376166 | Nocardia strain New antibiotically active compounds having the basic structure of rifamycin S, namely 3-hydroxyrifamycin S (formula A: X= | 03/08/1983 |
| 4374129 | Antibiotically active aminopapulacandin derivatives N-acylated 11-amino derivatives of papulacandin A or B of the formula I ##STR1## in which Pap is the remainder of papulacandin A or B, R represents methyl or hydrogen and Ac represents the acyl radical of an organic acid, including salts of compounds... | 02/15/1983 |
| 4369179 | Acylpeptides Acylpeptides derived from somatostatin or from a derivative thereof having analogous action, in which the amino acids sequence is modified by omitting individual amino acids and/or by exchanging them for other amino acids, and in which the &3xb5;-amino gr... | 01/18/1983 |
| 4364865 | Bicyclic unsaturated thia-aza compounds and 4-acylthio azetidinone intermediates The invention relates to 6-amino-2-penem-3-carboxylic acid compounds of the formula ##STR1## in which R1a denotes hydrogen or an amino protective group R1A and R1b represents hydrogen ... | 12/21/1982 |
| 4361558 | Halogenated steroids Novel halogenated steroids of the formula ##STR1## in which X represents a halogen atom having a maximum atomic number of 17, Y represents a hydrogen atom or hydroxyl, and R represents an alkyl radical having a maximum of 6 carbon atoms, and their 1,2-dehydro ... | 11/30/1982 |
| 4359555 | Salts formed from formamidines with polymers containing sulfonic acid groups Salts of formamidines with polymers containing sulfonic acid groups; processes for producing these salts; and the use thereof in combating pests.... | 11/16/1982 |
| 4358439 | Cyclooctapeptides Cyclic peptides of the formula ##STR1## in which trp represents L-Trp, D-Trp, or an analogous radical which carries a halogen atom in the indole nucleus, AcA represents hydrogen, or an acyl radical Ac of a carboxylic acid present at the ... | 11/09/1982 |
| 4353918 | Dextrorotatory bicyclic thiadiaza compounds and pharmaceutical preparations containing them The invention relates to the dextrorotatory enantiomer of trans-5,6-di-p-methoxyphenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole and its pharmaceutically acceptable salts and to pharmaceutical preparations containing them. The new compounds have valuable p... | 10/12/1982 |
| 4353887 | Divisible tablet having controlled and delayed release of the active substance Divisible tablet having controlled and delayed release of the active substance and consisting of a compact that is optionally provided with a coating and is formed by at least one active substance in an adjunct composition that effects a delayed and contr... | 10/12/1982 |
| 4353826 | Substituted rifamycins Antibiotically active compounds derived from rifamycin S or from the corresponding hydroquinone, rifamycin SV, or from derivatives at least partially hydrogenated in positions 16, 17; 18, 19; 28, 29, such as the 16, 17; 18, 19--tetrahydro- or the 16, 17; ... | 10/12/1982 |
| 4344957 | Benz-acyl-benzimidazole derivatives and antiallergic compositions New heterocyclylcarboxylic acid derivatives which are acylated in the nucleus, especially benz-acyl-benzimidazole-2-carboxylic acid derivatives of the formula ##STR1## in which R is a free, esterified or amidated carboxyl group or a free, etheri... | 08/17/1982 |
| 4331676 | Thia-aza compounds with a ଲ-lactam ring 2-Penem-3-carboxylic acid compounds of the formula ##STR1## in which R1 represents hydrogen, an organic radical bonded by a carbon atom to the ring carbon atom or an etherified mercapto group and R2 represents hydroxy or a radical R | 05/25/1982 |
| 4329348 | N-Oxacyclic-alkylpiperidines as psychostimulants N-Oxacyclic-alkylpiperidyl-diazacompounds, e.g., those of the formula ##STR1## and salts thereof are antidepressants and psychostimulants.... | 05/11/1982 |
| 4328214 | Cyclopeptides and pharmaceutical preparations thereof and also processes for their manufacture The somatostatin-analogous cyclic octapeptides according to the invention of the general formula ##STR1## in which trp represents L-Trp or D-Trp, in which the benzene ring may be substituted by a halogen atom, and Gaba(Ar) represents the residue of a... | 05/04/1982 |
| 4327091 | N,N-Di and N,N,N-tri(hydroxy-lower alkyl) ammonium salts of substituted 3,4-dihydro-2H-1,2-benzothiazine 1,1 dioxide and pharmaceutical compositions thereof 3,4-Dihydro-2H-1,2-benzothiazine 1,1-dioxides of the formula ##STR1## wherein Ph represents a substituted or unsubstituted 1,2-phenylene radical, R represents a substituted or unsubstituted benzopyrone radical, and R1 represents hydrogen o... | 04/27/1982 |
| 4323688 | Benzimidazole-2-carboxylic acid and derivatives thereof Novel substituted heterocyclyl compounds of the formula ##STR1## in which R is a free, esterified or amidated carboxyl group or a free, etherified or esterified hydroxymethyl group, R1 is an aliphatic, cycloaliphatic, aromatic, araliphatic... | 04/06/1982 |
| 4323560 | Novel phosphorylmuramyl peptides and processes for the manufacture thereof Phosphorylmuramyl peptides of the formula ##STR1## are immuno-potentiating. In the formula, R1 represents optionally substituted alkyl or aryl, R2, R4, R6 and R7 represent, for example, hydrogen,... | 04/06/1982 |
| 4322431 | Pharmaceutical preparations containing benzimidazole 2-derivatives Benzimidazole 2-derivatives that are acylated in the nucleus and have the formula ##STR1## in which R1 represents an aliphatic, cycloaliphatic, aromatic, araliphatic, heterocyclic or heterocyclic-aliphatic radical, R2 represents... | 03/30/1982 |
| 4322419 | Bicyclomycin derivatives, compositions thereof and process of use thereof Derivatives of 5-norbicyclomycin of the formula ##STR1## wherein R represents an unsubstituted or substituted monovalent hydrocarbon radical in which one, two or more carbon atoms can be replaced by heteroatoms, and X represents a bivalent group of t... | 03/30/1982 |
