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Number of applications: 489
Last date: February 24, 2011

1                      
Application No.Application TitleIssue Date
20110045582METHODS AND APPARATUS FOR INTEGRATED CELL HANDLING AND MEASUREMENTS
Method and systems that provide improved cell handling and assays in microfluidic systems and devices particularly using lateral cell trapping and methods of fabrication of the same....
02/24/2011
20110035818DIAGNOSTIC MARKER AND PLATFORM FOR DRUG DESIGN IN MYOCARDIAL INFARCTION AND HEART FAILURE
Methods for determining the susceptibility of an individual to a heart condition, post myocardial infarction, comprising detecting the presence of an amino acid change in the sequence of the hemopexin domain of MMP-9 (Matrix Metalloproteinase 9), the presence of an amin...
02/10/2011
20110034038Methods and devices for forming nanostructure monolayers and devices including such monolayers
Methods for forming or patterning nanostructure arrays are provided. The methods involve formation of arrays on coatings comprising nanostructure association groups, formation of arrays in spin-on-dielectrics, solvent annealing after nanostructure deposition, patterning...
02/10/2011
20110029519Population clustering through density-based merging
A method and/or system for analyzing data using population clustering through density based merging....
02/03/2011
20110027867Methods and compositions for the production of orthogonal tRNA-aminoacyltRNA synthetase pairs
This invention provides compositions and methods for generating components of protein biosynthetic machinery including orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNAs/synthetases. Methods for identifying orthogonal pairs are also p...
02/03/2011
20110023195Engineering single-gene-controlled staygreen potential into plants
The enzymes of the ACC synthase family are used in producing ethylene. Nucleotide and polypeptide sequences of ACC synthases are provided along with knockout plant cells having inhibition in expression and/or activity in an ACC synthase and knockout plants displaying a ...
01/27/2011
20110014650IN VIVO UNNATURAL AMINO ACID EXPRESSION IN THE METHYLOTROPHIC YEAST PICHIA PASTORIS
The invention provides orthogonal translation systems for the production of polypeptides comprising unnatural amino acids in methylotrophic yeast such as Pichia pastoris. Methods for producing polypeptides comprising unnatural amino acids in methylotrophic yeast ...
01/20/2011
20110009281METHODS FOR CREATING AND IDENTIFYING FUNCTIONAL RNA INTERFERENCE ELEMENTS
The invention relates to the control of gene expression. Specifically, the invention provides compositions and methods for the production and use of recombinant nucleic acid molecules that have the ability to specifically downregulate an expressed target gene in vivo. I...
01/13/2011
20110008782Site-specific incorporation of redox active amino acids into proteins
Compositions and methods of producing components of protein biosynthetic machinery that include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNAs/synthetases, which incorporate redox active amino acids into proteins are provided. Met...
01/13/2011
20100330162Spray freeze dry of compositions for pulmonary adminstration
This invention provides methods and compositions to preserve bioactive materials, such as viruses, bacteria, cells, or liposomes, in freeze dried particles suitable for pulmonary administration. Methods provide spray freeze drying of formulations to form stable freeze d...
12/30/2010
20100313304Engineering single-gene-controlled staygreen potential into plants
The enzymes of the ACC synthase family are used in producing ethylene. Nucleotide and polypeptide sequences of ACC synthases are provided along with knockout plant cells having inhibition in expression and/or activity in an ACC synthase and knockout plants displaying a ...
12/09/2010
20100304394Screening methods involving the detection of short-lived proteins
A method is provided for screening for agents that affect protein degradation rates, the method comprising: taking a library of cells, the cells expressing a fusion protein comprising a reporter protein and a protein encoded by a sequence from a cDNA library derived fro...
12/02/2010
20100302322MICROMACHINED FLUID EJECTOR
This invention relates to micromachined fluid ejector arrays having a fluid reservoir bounded at one side by an elastic membrane having scalable arrays of orifices arranged between concentric piezoelectric transducers, and bounded at another side by a top cover supporte...
12/02/2010
20100299780PLANT SUPEROXIDIE DISMUTASE EXPRESSION RESISTANT TO MICRO-RNA REGULATION
This invention provides variant sequences to miR398 targets in copper/zinc superoxide dismutase (CSD) genes resulting in resistance to down regulation of the CSD by the miR398....
11/25/2010
20100297693Production of carrier-peptide conjugates using chemically reactive unnatural amino acids
Provided are methods of making carrier polypeptide that include incorporating a first unnatural amino acid into a carrier polypeptide variant, incorporating a second unnatural amino acid into a target polypeptide variant, and reacting the first and second unnatural amin...
11/25/2010
20100297231PRESERVATION OF BIOACTIVE MATERIALS BY FREEZE DRIED FOAM
This invention provides methods, systems and compositions to preserve bioactive materials in a dried foam matrix. Methods provide non-boiling foam generation and penetration of preservative agents at temperatures near the phase transition temperature of the membranes. B...
11/25/2010
20100291700Analysis of membrane component interactions
Devices and methods for detecting interaction between components associated with lipid membranes and analytes are described herein. In certain methods, a surface of a compartment of a device is coated with a material that attaches to lipid membrane from a sample. An ana...
11/18/2010
20100291559Compositions of orthogonal lysyl-tRNA and aminoacyl-tRNA synthetase pairs and uses thereof
Compositions and methods of producing components of protein biosynthetic machinery that include orthogonal lysyl-tRNAs, orthogonal lysyl-aminoacyl-tRNA synthetases, and orthogonal pairs of lysyl-tRNAs/synthetases, which incorporate homoglutamines into proteins are provi...
11/18/2010
20100283640APPARATUS AND METHOD FOR FAST DATA ENCODING AND DECODING
An improved method for encoding and decoding data, such as in a base64 system, uses multiple look-up tables to perform the encoding function....
11/11/2010
20100276638Functionalized matrixes for dispersion of nanostructures
Matrixes doped with semiconductor nanocrystals are provided. In certain embodiments, the semiconductor nanocrystals have a size and composition such that they absorb or emit light at particular wavelengths. The nanocrystals can comprise ligands that allow for mixing wit...
11/04/2010
20100261247Active surface coupled polymerases
Active surface coupled polymerases, surfaces that include such polymerases, and methods of making and using surface-attached polymerases are provided....
10/14/2010
20100260465Protein engineering strategies to optimize activity of surface attached proteins
Isolated and/or recombinant enzymes that include surface binding domains, surfaces with active enzymes bound to them and methods of coupling enzymes to surfaces are provided. Enzymes can include large and/or multiple surface coupling domains for surface coupling....
10/14/2010
20100235403Method and system for on-line edit flow peer review
Methods and systems for journal peer review particularly for managing online peer review transactions over a network or communications medium such as via the Internet. In specific embodiments, that system minimizes or eliminates the need for most participants to remembe...
09/16/2010
20100234986METHOD AND SYSTEMS FOR COLLECTING INVENTORY AND MARKETING DATA, PROVIDING DATA AND VIDEO SERVICES
Methods and systems for providing inventory and/or marketing services using distributed devices and a network or communications medium such as via the Internet. In specific embodiments, a thin client logic system is installed at multiple item dispensers and communicates...
09/16/2010
20100226939FORMULATIONS FOR PRESERVATION OF ROTAVIRUS
This invention provides formulations and methods for stabilizing viruses in liquid and dried formulations. In particular, formulations are provided including Zn2+ cations that stabilize the viability of Rotaviruses. Methods of vaccination include neutralizati...
09/09/2010
20100211186ELECTROACTIVE POLYMER ACTUATION OF IMPLANTS
This invention provides methods and devices for reconstructing muscular responses in patients with paralysis. Electroactive polymer (EAP) actuators power implants attached to tissues in the patients. When the actuators are energized, the implants move the tissues approp...
08/19/2010
20100188665Methods and systems for interferometric analysis
This invention provides methods and devices for analyzing interference patterns. The methods include fitting a Gaussian distribution to a cross correlation of two patterns from interferometric analysis of a liquid at a first and second time; identifying a positional shi...
07/29/2010
20100187842Pick up device with locking mechanism and leverage action trigger
This invention provides hand operated portable devices for grasping and manipulation of objects as well as methods of their use....
07/29/2010
20100184190Influencing viral lipid constituents
This invention provides compositions, methods and systems to modulate the lipid content and membrane characteristics of cells and virions. Growth of host cells on media containing particular amounts, classes and/or combinations of lipid supplements can influence the lip...
07/22/2010
20100184056Sample collection and measurement in a single container by back scattering interferometry
This invention provides a device and method for collection and analysis of heterogeneous samples in a single sample container by back scattering interferometry. The sample container is configured to allow collection of a heterogeneous sample, such as blood, from a subje...
07/22/2010
20100183200Fingerprint Input Module
A fingerprint input module includes at least one prism sheet, an image-capturing unit, and a planar light source. The prism sheet has a micro-prism array. The image-capturing unit has a lens. The planar light source is disposed between the prism sheet and the image-capt...
07/22/2010
20100172552Fingerprint indentifying system
A fingerprint identifying system includes a finger press plate, an image-capturing unit, a light-diffusion member, at least one microstructure layer, and a light source. The light-diffusion member is disposed below the finger press plate and above the image-capturing un...
07/08/2010
20100155786Methods and devices for forming nanostructure monolayers and devices including such monolayers
Methods for forming or patterning nanostructure arrays are provided. The methods involve formation of arrays on coatings comprising nanostructure association groups, formation of arrays in spin-on-dielectrics, solvent annealing after nanostructure deposition, patterning...
06/24/2010
20100145715METHOD AND/OR SYSTEM FOR PROVIDING AND/OR ANALYZING AND/OR PRESENTING DECISION STRATEGIES
A method and/or system that can be implemented on a computing device or tables or board game or otherwise uses a rule set to evaluate data about a situation and actors in order to provide advice regarding strategies for influencing actors and/or other outputs....
06/10/2010
20100144600Osteoprotegerin variant proteins
The present invention relates to novel osteoprotegerin variant proteins (OVPs) that demonstrate reduce binding affinity for their ligand TRAIL when compared to wild-type osteoprotegerin. Nucleic acids which encode these OVPs are also provided. Recombinant vectors and ho...
06/10/2010
20100144543Epigenetic silencing of tumor suppressor genes
Provided are methods of identifying a compound that binds to or modulates an activity of a CTCF polypeptide or CTCF polypeptide complex. Also provided are methods of monitoring a cancer state of a cell by detecting a chromatin boundary proximal to a tumor suppressor gen...
06/10/2010
20100141169LIGHTING SYSTEMS
A power adaptor (20) for a lighting unit (50) having a solid state light source (50a,50b,50c) is disclosed. The power adaptor (20) comprises an input (22) for connection to a mains power supply, a pow...
06/10/2010
20100140551Nanocrystal doped matrixes
Matrixes doped with semiconductor nanocrystals are provided. In certain embodiments, the semiconductor nanocrystals have a size and composition such that they absorb or emit light at particular wavelengths. The nanocrystals can comprise ligands that allow for mixing wit...
06/10/2010
20100132576Detonator System
A detonator system which includes an array of a plurality of discrete time delay relays (16) connected in series to one another, and a plurality of detonators (28) which are respectively connected to the array at spaced intervals (22)....
06/03/2010
20100130949Catheter drainage system
This invention provides systems and methods to collect biological fluids from a catheterized or intubated animal. Drainage tubes are provided that reduce fluid back pressure by avoiding the formation of dependent loops. Low aspect ratio collection receptacles are provid...
05/27/2010
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