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Patent No. 5500234

Crispy Chip Sandwich and Process of Producing a Sandwich Product

A food product comprising a multilayer cookie or snack having outer layers formed from a crispy type edible food product such as a potato chip or corn chip, etc. with an intermediate marshmallow layer being in contact with the inner surface of each crispy chip and one or more filler substances.

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Attorney: NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH, INC.


Number of applications: 376
Last date: February 24, 2011

1                    
Application No.Application TitleIssue Date
20110046133ORGANIC COMPOUNDS
The present invention provides compounds of the following structure;


A-L1-B-C-D

that are useful for treating or preventing conditions or disorders associated with DGAT1 ac...

02/24/2011
201100398313-HETEROARYLMETHYL-IMIDAZO[1,2-B]PYRIDAZIN-6-YL DERIVATIVES
The invention relates to compounds of formula (I) and salts thereof

wherein the substituents are as defined in the specification, the application of a compound of formula (I) in a process for the treatment of...

02/17/2011
20110039759Use of Secretin-Receptor Ligands in Treatment of Cystic Fibrosis (CF) and Chronic Obstructive Pulmonary Disease (COPD)
The invention is based on the finding that the secretin receptor is expressed in tissues present in the distal lung of humans. In patient with CF, levels of the receptor are elevated compared to the normal tissue. Treatment of tissue by secretin stimulates the movement ...
02/17/2011
20110038866IMPROVED FIBRONECTIN-BASED BINDING MOLECULES AND USES THEREOF
The invention provides fibronectin type III (Fn3)-based binding molecules that bind to a specific target antigen. The invention further provides bispecific Fn3-based binding molecules that bind to two or more targets simultaneously. The Fn3-based binding molecules of th...
02/17/2011
20110034418PHARMACEUTICAL COMPOSITION WITH BISPHOSPHONATE
The present invention relates to depot formulations comprising a poorly water soluble salt of a bisphosphonate forming together with one or more biocompatible polymers, to poorly water-soluble salts of such bisphosphonates, to crystalline forms of the free compounds and...
02/10/2011
20110028492Heteroaryl Compounds and Their Uses
The present invention provides a compound of formula (I):

and pharmaceutically acceptable salts, enantiomers, stereoisomers, rotamers, tautomers, diastereomers, or racemates thereof. Also provided is a method...

02/03/2011
20110021520OXAZINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF NEUROLOGICAL DISORDERS
The invention relates to novel heterocyclic compounds of the formula

in which all of the variables are as defined in the specification, in free form or in salt form, to their preparation, to their medical use...

01/27/2011
20110015232Pyrrolydine Derivatives as IAP Inhibitors
The present invention relates to novel IAP inhibitor compounds of: Formula (I).

...

01/20/2011
20110015180Chemokine receptor antagonists
A compound of formula (I) or a pharmaceutically acceptable salt or prodrug ester thereof:

wherein the variants R, R9, Z, X, Q and Y are defined in the specification....

01/20/2011
20110014186ARYLSULFONAMIDE-BASED MATRIX METALLOPROTEASE INHIBITORS
The present invention provides a compound of formula (I):

said compound is inhibitor of MMP-2, and/or MMP-8, and/or MMP-9, and/or MMP-12 and/or MMP-13, and thus can be employed for the treatment of a disorder...

01/20/2011
20110009459EPOTHILONE DERIVATIVES
Epothilone derivatives of Formula (I) and their use as a pharmaceutical.

...

01/13/2011
20110009429HETEROCYCLIC COMPOUNDS AS INHIBITORS OF CXCR2
The present invention relates to compounds of formula (I)

wherein R1, R2, X, Y and Z are as defined in the specification....

01/13/2011
20110009399ORGANIC COMPOUNDS
The application relates to trisubstituted piperidines of the general formula (I) and their salts, preferably their pharmaceutically acceptable salts, in which R1, R2′, X, U, W, m and n have the meanings explained in the description, a process for...
01/13/2011
20110003818Substituted 2-Carboxamide Cycloamino Ureas
The present invention relates to compounds of formula I

and salts thereof, wherein the substituents are as defined in the description, to compositions and use of the compounds in the treatment of diseases ame...

01/06/2011
20110003791Cyclized Derivatives as EG-5 Inhibitors
The present invention relates to new substituted imidazole compounds have the following Formula (I) and to the pharmaceutically acceptable salts, esters, or prodrugs thereof, to compositions of the compounds together with pharmaceutically acceptable carriers, and to use...
01/06/2011
201100037862-Carboxamide Cycloamino Ureas
The present invention relates to compounds of formula I

and salts thereof, wherein the substituents are as defined in the description, to compositions and use of the compounds in the treatment of diseases ame...

01/06/2011
20110002845METHODS OF TREATING, DIAGNOSING OR DETECTING FGF21-ASSOCIATED DISORDERS
The invention provides, inter alia, methods for treating cancer and vascular disease, compositions for treating cancer and vascular disease, and methods and compositions for diagnosing and/or detecting cancer and vascular disease....
01/06/2011
20100331326Inhibitors of CYP 17
The present invention provides compounds of Formula (I) and (II), or a pharmaceutically acceptable salts thereof,

where R53, R54, p, q, and n are as defined herein. The compounds of the ...

12/30/2010
20100331322SUBSTITUTED PIPERIDINES AS RENIN INHIBITORS
The present invention relates to compounds of the general formula (I) and the salts thereof, preferably the pharmaceutically acceptable salts thereof; in which R has the meaning explained in the description, a process for their preparation and the use of these compounds...
12/30/2010
20100331243ORGANIC COMPOUNDS AND THEIR USES
The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of human diseases....
12/30/2010
20100330021SUBSTITUTED (THIAZOL-2-YL)-AMIDE OR SULFONAMIDE AS GLYCOKINASE ACTIVATORS USEFUL IN THE TREATMENT OF TYPE 2 DIABETES
Compounds of the formula


R—NH-Q  (I)

provide pharmacological agents which are glucokinase activators and thus may be employed for the treatment of glucokinase mediat...

12/30/2010
20100324083Combinations of Organic Compounds
The invention provides a pharmaceutical combination comprising:
    • a) compounds that inhibit the binding of the Smac prote...
12/23/2010
20100322930FIBRONECTIN-BASED BINDING MOLECULES AND THEIR USE
The invention provides fibronectin-based binding molecules and methods for introducing donor CDRs into a fibronectin-based binding scaffold, in particular, Fn3. The fibronectin-based binding molecules of the invention may be further conjugated to another moiety, for exa...
12/23/2010
20100322926METHODS OF USING CADHERIN 11 (CDH11) ANTAGONISTS
The present invention provides novel methods of inhibiting or preventing epithelial-mesenchymal transition (EMT) or endothelial-mesenchymal transition (EnMT), such as EMT or EnMT, associated with fibrosis and chronic tissue rejection. The present invention also provides...
12/23/2010
20100317699USE OF HEDGEHOG AGONISTS IN THE TREATMENT OF MUSCULOSKELETAL-RELATED DISORDERS
The invention provides methods for the diagnosis and treatment of musculoskeletal disorders relating to the Hedgehog pathway, including but not limited to muscular dystrophy (e.g., Duchenne Muscular Dystrophy) using agents that agonize Sonic Hedgehog (shh), and thereby,...
12/16/2010
201003176571H-IMIDAZO[4,5-c]QUINOLINONE DERIVATIVES
The invention relates to the use of 1H-imidazo[4,5-c]quinolinone derivatives and salts thereof in the treatment of protein and/or lipid kinase dependent diseases and for the manufacture of pharmaceutical preparations for the treatment of said diseases; 1H-imidazo[4,5-c]...
12/16/2010
20100317621BETA-LACTAMASE INHIBITORS
Disclosed herein are α-aminoboronic acids and their derivatives which act as inhibitors of beta-lactamases. Also disclosed herein are pharmaceutical compositions comprising α-aminoboronic acids and methods of use thereof....
12/16/2010
20100316573Organic Compounds
A method to predict which patients will respond to a IAP inhibiting compound comprising:
    • a) administering an IAP inhibi...
12/16/2010
20100313285Altering High Density Lipoprotein Levels Through UDP-N-Acetyl-Alpha-D-Galactosamine: Polypeptide N-Acetlgalactosaminyltransferase (GALNT) Modulation
Described herein are methods for detecting and treating coronary artery disease and atherosclerotic conditions based on modulating the levels of total plasma lipoprotein and HDL-C by inhibiting expression or activity of GALNT. Also described herein are methods for ident...
12/09/2010
20100311750ORGANIC COMPOUNDS
The present invention provides a compound of formula (I): wherein the variants R1, R2, R3, R4, R6, R7 are as defined herein, and wherein said compound is an inhibitor of CETP, and thus can be employed for the treatment of a disorder or disease mediated by CETP or respon...
12/09/2010
20100311729Substituted imidazopyridazines and pyrrolopyrimidines as lipid kinase inhibitors
The present invention relates to compounds are of the formula I,

processes for the preparation thereof, more generally these compounds for use in the treatment of the human or animal body, in the treatment of...

12/09/2010
201003117141H-IMIDAZO[4,5-c]QUINOLINONE COMPOUNDS
The invention relates to the use of 1H-imidazo[4,5-c]quinolinone compounds and salts thereof in the treatment of protein and/or lipid kinase dependent diseases and for the manufacture of pharmaceutical preparations for the treatment of said diseases; 1H-imidazo[4,5-c]qu...
12/09/2010
20100305145Substituted Aminobutyric Derivatives as Neprilysin Inhibitors
The present invention provides a compound of formula I′;

or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, X and n are defined herein. The invention also re...

12/02/2010
20100305131Substituted Aminopropionic Derivatives as Neprilysin inhibitors
The present invention provides a compound of formula I′;

or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R5, B1, X and n are defined...

12/02/2010
20100305113Substituted Imidazopyridazines as Lipid Kinase Inhibitors
The invention relates to novel compounds of the formula I,

as well as other invention embodiments related to these compounds. The compounds are e.g. useful in the treatment of the animal or human body in view...

12/02/2010
20100305036COMBINATION OF PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND HUMAN GROWTH HORMONE FOR THE TREATMENT OF MUSCLE ATROPHY AND RELATED DISORDERS
The invention relates to the use of a combination of protein tyrosine phosphatase inhibitors and human growth hormone for the treatment of musculoskeletal diseases, particularly for the treatment of muscle atrophy....
12/02/2010
20100303926ORGANIC COMPOUNDS
The present invention relates to compounds of the general formula (I) and the salts thereof, preferably the pharmaceutically acceptable salts thereof; in which in which R1 has the meaning explained in the description, a process for their preparation and the u...
12/02/2010
20100298337Organic Compounds
Compounds of formula (I) in free or salt or solvate form, where T1, T2, and T3 have the meanings as indicated in the specification, are useful for treating inflammatory or obstructive airways, pulmonary hypertension, pulmonary fibrosis, ...
11/25/2010
20100298286Organic Compounds
The present invention relates to a compound of formula I

    • and its salts, wherein the subs...
11/25/2010
20100292225ARYL PYRIDINE AS ALDOSTERONE SYNTHASE INHIBITORS
The present invention provides a compound of formula I;

a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacolog...

11/18/2010
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