Bizarre Patents
A fork with timer for providing a cue to a user after an elapsed period of time for indicating that another bite of food using the fork may be taken.
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Application No. | Application Title | Issue Date |
| 20110046166 | PURINE DERIVATIVES AS A3 ADENOSINE RECEPTOR-SELECTIVE AGONISTS Disclosed are (N)-methanocarba adenine nucleosides, e.g., of formula (I) as highly potent A3 adenosine receptor agonists, pharmaceutical compositions comprising such nucleosides, and a method of use of these nucleosides, wherein R1-R6 ar... | 02/24/2011 |
| 20110034547 | CHONDROPSIN-CLASS ANTITUMOR V-ATPASE INHIBITOR COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF A composition comprising a substantially purified compound of the formula: in combination with at least one additional therapeutic agent, and methods of preventing or treating cancer and a condition treatable... | 02/10/2011 |
| 20110027299 | MELANOMA ANTIGENS AND THEIR USE IN DIAGNOSTIC AND THERAPEUTIC METHODS The present invention provides an isolated or purified immunogenic peptide comprising 8-15 contiguous amino acids of gp100 (SEQ ID NO: 121) and related nucleic acids, expression vectors, host cells, populations of cells, and methods of use. The invention further provide... | 02/03/2011 |
| 20110014120 | TRIFUNCTIONAL IMAGING AGENT FOR MONOCLONAL ANTIBODY TUMOR-TARGETED IMAGING The present invention relates to trifunctional imaging agents that include an antibody for cell targeting, as well as a chelating moiety for sequestering radioisotopes and a fluorescing moiety for imaging. The invention also provides methods using the conjugates for med... | 01/20/2011 |
| 20110010171 | Singular Value Decomposition for Improved Voice Recognition in Presence of Multi-Talker Background Noise A system and method for providing speech recognition functionality offers improved accuracy and robustness in noisy environments having multiple speakers. The described technique includes receiving speech energy and converting the received speech energy to a digitized f... | 01/13/2011 |
| 20100322910 | METHODS OF OBTAINING ANTIGEN-SPECIFIC T CELL POPULATIONS The invention provides a method of obtaining a population of antigen-specific T cells from peripheral blood of a host. An embodiment of the method of the invention comprises (i) dividing PBMCs from peripheral blood of a host into more than one sub-population; (ii) conta... | 12/23/2010 |
| 20100317837 | IDENTIFICATION OF NOVEL BROADLY CROSS-REACTIVE NEUTRALIZING HUMAN MONOCLONAL ANTIBODIES USING SEQUENTIAL ANTIGEN PANNING OF PHAGE DISPLAY LIBRARIES The present invention provides a method of identifying novel broadly crossreactive neutralizing monoclonal antibodies using sequential antigen panning of phage display libraries, antibodies obtained in accordance with such a method, as well as fusion proteins and conjug... | 12/16/2010 |
| 20100317732 | METHOD OF INHIBITING ABCG2 AND OTHER TREATMENT METHODS Disclosed are methods of enhancing the chemotherapeutic treatment of tumor cells, reducing resistance of a cancer cell to a chemotherapeutic agent, a method of inhibiting ABCG2, Pgp, or MRP1 in a mammal afflicted with cancer, and a method of increasing the bioavailabili... | 12/16/2010 |
| 20100314250 | STABILIZATION OF COMPLEXES FOR GEL MOBILITY SHIFT, CHROMATOGRAPHY, AND CAPILLARY ELECTROPHORESIS The invention provides a method of separating a complex comprising a first agent bound to a second agent from unbound agents comprising (a) preparing a gel comprising a gel matrix and a neutral solute, (b) placing one or more samples comprising the complex and unbound a... | 12/16/2010 |
| 20100298248 | BIOLOGICALLY ACTIVE MACROLIDES, COMPOSITIONS, AND USES THEREOF The present invention provides a compound of the formula (I) or (II, wherein R1 is H, alkyl, alkenyl or aryl, R2 is H, alkyl or aryl, R3 is H, a alkyl, alkenyl or aryl, R4 and R4-R8 are independently R 11/25/2010 | |
| 20100297093 | MODIFIED T CELL RECEPTORS AND RELATED MATERIALS AND METHODS The invention is directed to a modified T cell receptor (TCR) comprising an amino acid sequence of a wild-type (WT) TCR with one or more amino acid substitutions in the CDR2 and/or CDR3 regions of the alpha and/or beta chains of the TCR, wherein the modified TCR, as com... | 11/25/2010 |
| 20100286259 | EPOXY-GUAIANE DERIVATIVES AND TREATMENT OF CANCER Disclosed are englerins and derivatives (I) thereof useful in the treatment of a number of cancers, particularly renal cancer, as well as pharmaceutical compositions and method of treating a patient with the use of these derivatives. The englerins, for example Englerin ... | 11/11/2010 |
| 20100279950 | PEPTIDES OF A MELANOMA ANTIGEN AND THEIR USE IN DIAGNOSTIC, PROPHYLACTIC, AND THERAPEUTIC METHODS Immunogenic peptides of a melanoma antigen recognized by T cells, designated gp100, bioassays using the peptides to diagnose, assess or prognose a mammal afflicted with cancer, more specifically melanoma or metastatic melanoma, and use of the proteins and peptides as im... | 11/04/2010 |
| 20100267712 | ISOINDOLINE COMPOUNDS FOR THE TREATMENT OF SPINAL MUSCULAR ATROPHY AND OTHER USES Disclosed is a compound of Formula (I) in which W and R1-R6 are defined herein. Also disclosed is a method of treating spinal muscular atrophy, as well as methods of using such compounds to increase SMN expression, increase EAAT2 expression, or inc... | 10/21/2010 |
| 20100267652 | METHOD OF INHIBITING ABCG2 AND RELATED TREATMENTS Disclosed are methods of enhancing the chemotherapeutic treatment of tumor cells, reducing resistance of a cancer cell to a chemotherapeutic agent, a method of inhibiting ABCG2 or MRP1 in a mammal afflicted with cancer, and a method of increasing the bioavailability of ... | 10/21/2010 |
| 20100256098 | COMPOUNDS FOR INHIBITING WIP1, PRODRUGS AND COMPOSITIONS THEREOF, AND RELATED METHODS The invention provides compounds useful in inhibiting the activity of a Wip1 protein in a cell as well as prodrugs thereof, related methods of use and compositions which include the aforesaid compounds and prodrugs thereof. The compounds comprise a ring structure having... | 10/07/2010 |
| 20100254899 | RADIOLABELED AFFIBODY MOLECULES The invention provides a radiolabeled affibody molecule comprising a fragment of an IgG-binding domain of protein A from Staphylococcus aureus, a bifunctional linker, and a radiolabel comprising 18F or 76Br, wherein the bifunctional linker l... | 10/07/2010 |
| 20100254898 | ANTIBODIES THAT BIND GalNAc1-3Gal, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING SAME Monoclonal antibodies to carbohydrate antigens containing a terminal GalNAcα1-3Gal are provided. The antibodies of the present invention are found to specifically recognize GalNAcα1-3Gal with little cross-reactivity to other structurally similar antigens such as GalNA... | 10/07/2010 |
| 20100248695 | Restoring Connectivity To A Desubscribed Telematics Unit Aspects of the invention include a method and system for restoring connectivity from a telematics service provider to a desubscribed telematics unit, and therefore, restored a capability of providing telematics services to a vehicle owner. A vehicle owner with a lapsed ... | 09/30/2010 |
| 20100247528 | ARRAYS, KITS AND CANCER CHARACTERIZATION METHODS The invention provides an array comprising a substrate and a set of addressable elements, wherein each addressable element comprises (i) a polynucleotide that specifically binds to a target molecule, (ii) a polypeptide that specifically binds to target molecule, or (iii... | 09/30/2010 |
| 20100245122 | Unit Configuration/Reactivation Through VDU Services A system and method for activating an inactive telematics unit provides a group of communications functions to the telematics unit. Initially, a call is received at a call center from a user of the telematics unit, through which subscriber information is obtained. An ac... | 09/30/2010 |
| 20100240578 | ANTI-H5N1 INFLUENZA ACTIVITY OF THE ANTIVIRAL PROTEIN CYANOVIRIN The invention is directed to a method of inhibiting prophylactically or therapeutically an H5N1 viral infection in a host, which method comprises administering to the host an anti-viral effective amount of an antiviral protein comprising the amino acid sequence of SEQ I... | 09/23/2010 |
| 20100221242 | ANTI-VIRAL GRIFFITHSIN COMPOUNDS, COMPOSITIONS AND METHODS OF USE A method of inhibiting a viral infection of a host comprising administering to the host an anti-viral griffithsin polypeptide comprising SEQ ID NO: 3 or a fragment thereof comprising at least eight contiguous amino acids, a nucleic acid encoding the anti-viral polypepti... | 09/02/2010 |
| 20100209386 | AGONIST AND ANTAGONIST PEPTIDES OF CARCINOEMBRYONIC ANTIGEN (CEA) The invention provides a peptide comprising an agonist of a MHC Class I binding native sequence having amino acid substitution(s) and enhanced immunogenicity compared to the native sequence. The invention also provides methods comprising the administration of the peptid... | 08/19/2010 |
| 20100204172 | INACTIVATORS OF O6-ALKYLGUANINE-DNA ALKYLTRANSFERASE Disclosed are compounds that are AGT inactivators that include a folate residue, e.g., a compound of formula (I), wherein X1, X2, R1, and R2 are as described herein. Also disclosed is a pharmaceutical composition comprising a ... | 08/12/2010 |
| 20100190493 | SYSTEM AND METHOD FOR CORRECTING A MOBILE IDENTIFICATION NUMBER A system for correcting or updating a mobile identification number in a cellular telephone portion of a telematics unit installed in a vehicle allows service providers to resolve duplicate entries. A wireless service provider stores a triplicate entry in their HLR for c... | 07/29/2010 |
| 20100184697 | PEPTIDE-BASED STAT INHIBITOR A peptide or peptidomimetic comprising the amino acid sequence of the second helix of a STAT protein, or a variant of such sequence, wherein the peptide or peptidomimetic comprises about 40 or fewer amino acids and binds to a STAT protein, as well as a method of inhibit... | 07/22/2010 |
| 20100179188 | NITROXIDE RADICAL AS TREATMENT FOR NEURODEGENERATION A method of treating or preventing neurodegeneration in a mammal comprising administering to the mammal an effective amount of a stable nitroxide radical, such as Tempo1, as well as related methods.... | 07/15/2010 |
| 20100168165 | METHOD OF TREATING DISEASE INVOLVING MYELIN AND/OR AXONAL LOSS Disclosed is a method of treating a disease involving myelin and/or axonal loss, such as a demyelinating disease, in a mammal comprising administering a compound of formula I in which R1-R11 <... | 07/01/2010 |
| 20100166707 | EXTRACELLULAR MATRIX/METASTASIS MODIFIER GENES FOR THE PREVENTION OR INHIBITION OF METASTASIS OR GROWTH OF TUMOR AND FOR CHARACTERIZATION OF TUMOR Disclosed are methods involving the administration of an extracellular matrix (ECM)/metastasis modifier gene, e.g., Anakin, Necdin, CentaurinD3 (CentD3), Csf1r, Brd4, Pi16, and Luc7l, for the prevention or inhibition of metastasis or of tumor growth. Further disclosed a... | 07/01/2010 |
| 20100158881 | ACTIVATED DUAL SPECIFICITY LYMPHOCYTES AND THEIR METHODS OF USE The present invention relates to preventive, therapeutic, and diagnostic compositions and methods employing lymphocytes having T-cell receptors and chimeric receptors. In particular, the invention relates to pre-selected dual-specificity lymphocytes having endogenous T-... | 06/24/2010 |
| 20100150960 | COMPOSITIONS AND METHODS FOR CHITOSAN ENHANCED IMMUNE RESPONSE The present invention features methods and compositions related to chitosan antigen depots, and chitosan cytokine depots, and the use of depot compositions in treating and preventing diseases.... | 06/17/2010 |
| 20100136056 | NOVEL INSERTION SITES IN POX VECTORS The present invention provides novel insertion sites for introducing DNA into pox vectors.... | 06/03/2010 |
| 20100135958 | METHOD FOR TREATING CANCER IN HUMANS A method of treating and/or preventing cancer in a subject, preferably mammalian, more preferably human, by administering in an effective amount IL-21 polypeptide, polynucleotide, vector comprising an IL-21 nucleic acid sequence encoding an IL-21 polypeptide, variants, ... | 06/03/2010 |
| 20100120817 | AZONAFIDE DERIVED TUMOR AND CANCER TARGETING COMPOUNDS An azonafide-based compound of Formula I, a composition comprising the compound, and a method of using the compound to deliver a cytotoxic azonafide derivative to a cell, as well as related compounds and methods for the use thereof to pre-pare an azonafide-based compoun... | 05/13/2010 |
| 20100113602 | USE OF HISTONE DEACETYLASE INHIBITORS FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM METASTASES Disclosed is a method of treating a localized carcinoma central nervous system (CNS) metastasis of extra-CNS origin, the method comprising systemically administering an effective amount of a histone deacetylase (HDAC) inhibitor (HDI) to a subject in need of treatment fo... | 05/06/2010 |
| 20100113408 | 21-SUBSTITUTED PROGESTERONE DERIVATIVES AS NEW ANTIPROGESTATIONAL AGENTS A compound having the general formula: in which: R1 is a member selected from the group consisting of —OCH3, —SCH3, —N(CH3)2, —NHCH3, ... | 05/06/2010 |
| 20100112626 | Use of Semenogelin in the Diagnosis, Prognosis and Treatment of Cancer Method of diagnosing cancer in a mammal comprising assaying a test sample from the mammal for an increased level of semenogelin, wherein the increased level of semenogelin in the test sample is diagnostic for the cancer; methods of prognosticating and assessing the effe... | 05/06/2010 |
| 20100111998 | HIV VACCINES BASED ON ENV OF MULTIPLE CLADES OF HIV In one embodiment, the invention provides a multiclade HIV plasmid DNA or viral vector vaccine including components from different clades of Env (optionally Env chimeras) and Gag-Pol-(optionally)Nef from a single Glade. The vaccine of the invention may further include V... | 05/06/2010 |
| 20100105707 | METHOD OF TREATING OR PREVENTING OXIDATIVE STRESS-RELATED DISEASE Disclosed is a method of treating or preventing an oxidative stress-related disease in a mammal in need thereof comprising administering an effective amount of a compound of formula (I) to the mammal, wherein R1-R4 and X1-X3 a... | 04/29/2010 |
