"Flight by machines heavier than air is unpractical and insignificant, if not utterly impossible."
Simon Newcomb, astronomer ; Said in 1902, less than two years before the first flight at Kitty Hawk
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| Application No. | Application Title | Issue Date |
| 20110038991 | SYSTEM FOR NUTRITIONALLY IMPROVING, PREPARING AND INTRODUCING INNOVATIONS INTO OILS FOR FOOD USE The invention relates to a method for nutritionally preparing oils for food use using natural and biological products and nutraceuticals, providing a system which is environmentally friendly and highly beneficial to the human body. The invention also relates to the prod... | 02/17/2011 |
| 20110034381 | Methods for Therapeutic Treatment of Benign Prostatic Hypertrophy (BPH) Therapeutic methods for treatment of benign prostatic hypertrophy by inhibition of the activity of insulin-like growth factor-I (IGF-I). Methods encompass the use of IGF-I antagonists, as well as the use of compounds that lower the effective level of IGF-I or interfere ... | 02/10/2011 |
| 20110028465 | AMIDE DERIVATIVES AS ION-CHANNEL LIGANDS AND PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME Compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditi... | 02/03/2011 |
| 20110028405 | SULFAMIDES AS ZAP-70 INHIBITORS The invention relates to compounds of formula (I) wherein X, R1, R2, R3, R8, R9 have the meaning as cited in the description and the claims. Said compoun... | 02/03/2011 |
| 20110027282 | INTERFERON ANTAGONISTS, ANTIBODIES THERETO AND ASSOCIATED METHODS OF USE Described are compositions and methods useful for modulating the immune system of a subject. Also included are diagnostic methods for monitoring an immunologic condition. In particular the invention relates to antagonists of interferon proteins and associated methods of... | 02/03/2011 |
| 20110021514 | AMIDE DERIVATIVES AS ION-CHANNEL LIGANDS AND PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME Compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limit... | 01/27/2011 |
| 20110021497 | AMINO TRIAZOLES AS PI3K INHIBITORS The invention relates to compounds of formula (I) wherein X, T1 and R1 to R3 have the meaning as cited in the description and the claims. Said compounds are useful as protein ... | 01/27/2011 |
| 20110021453 | Methods and compositions for providing cardiac protection The invention provides a method of treating a cardiac disease by administering a pharmaceutically effective amount of at least one compound capable of inhibiting AC5 to a patient. The compound capable of inhibiting AC5 may be administered singly or in combination with a... | 01/27/2011 |
| 20110020199 | Process for enhanced remediation of contaminated wastewaters, soils and wasteforms The present invention provides reagents that may be useful for treating wastes such as impure aqueous materials including wastewater to remove a significant proportion of the heavy metals that may be contained therein. The reagents include a calcium aluminosilicate (CAS... | 01/27/2011 |
| 20110014657 | Method for sequencing a polynucleotide template The invention relates to methods for pairwise sequencing of a double-stranded polynucleotide template, which methods result in the sequential determination of nucleotide sequences in two distinct and separate regions of the polynucleotide template. Using the methods of ... | 01/20/2011 |
| 20110009432 | PYRID-2YL FUSED HETEROCYCLIC COMPOUNDS, AND COMPOSITIONS AND USES THEREOF Fused heterocyclic compounds are provided according to formula 1a or 1b: where R1, R2, and R3 are as defined herein. Provided compounds and pharmaceutical compositions thereof... | 01/13/2011 |
| 20110009276 | Method for Sequencing a Polynucleotide Template The invention provides methods for pairwise sequencing of a double-stranded polynucleotide template, which methods result in the sequential determination of nucleotide sequences in two distinct and separate regions of the polynucleotide template.... | 01/13/2011 |
| 20110008725 | Marking liquid A liquid electrostatographic toner or liquid ink jet ink prepared by the steps of heating a marking particle mix of particles of a resin and a colourant blend in a carrier liquid to a temperature between about the first softening point of the resin and about the second ... | 01/13/2011 |
| 20110008291 | Use of antifungal compositions to treat upper gastrointestinal conditions The present invention provides a novel method for treating oral conditions and upper gastrointestinal conditions in a subject by providing an inventive oral dosage form of a pharmaceutical composition comprising an effective amount of at least one antifungal and optiona... | 01/13/2011 |
| 20100331359 | NOVEL COMPOUND USEFUL FOR THE TREATMENT OF DEGENERATIVE AND INFLAMMATORY DISEASES A compound is disclosed that has a formula represented by the following: This compound may be prepared as a pharmaceutical composition, and may be used for the prevention and treatment of a variety of conditi... | 12/30/2010 |
| 20100331319 | NOVEL COMPOUND USEFUL FOR THE TREATMENT OF DEGENERATIVE AND INFLAMMATORY DISEASES A novel compound able to inhibit JAK is disclosed, this compound may be prepared as a pharmaceutical composition, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, inflammat... | 12/30/2010 |
| 20100323383 | Methods for in vitro differentiation of Th-17+cells The present invention is directed to an in vitro method for promoting differentiation and proliferation of human T helper lymphocytes that express IL17 (Th-IL17+ cells). The instant method may be used to generate a population of human T hel... | 12/23/2010 |
| 20100322937 | EGF receptor epitope peptides and uses thereof The present invention relates generally to growth factor receptor epitope peptides, particularly EGF family receptor epitope peptides. The invention also relates to the use of the receptor peptides in generating antibodies which have anti-tumor or anti-cancer activity o... | 12/23/2010 |
| 20100317676 | Fused heterocyclic compounds, and compositions and uses thereof Fused heterocyclic compounds are disclosed that have formula 1: where A, B, L, N, R1, R3, R4′, Y and Z are as defined herein. The compounds and pharmaceutical compositions t... | 12/16/2010 |
| 20100317531 | Labelled nucleotides Nucleosides and nucleotides are disclosed that are linked to detectable labels via a cleavable linker group.... | 12/16/2010 |
| 20100311780 | Nitric oxide amino acid ester compound, composition for increasing nitirc oxide levels and method of use There is provided novel amino acid ester compounds comprising at least one nitric oxide releasing group and pharmaceutically acceptable salts thereof, and novel compositions comprising at least one amino acid ester compound comprising at least one nitric oxide releasing... | 12/09/2010 |
| 20100311597 | METHODS FOR SEQUENCE A POLYNUCLEOTIDE TEMPLATE The invention relates to methods for pairwise sequencing of a polynucleotide template which result in the sequential determination of nucleotide sequence in two distinct and separate regions of the polynucleotide template.... | 12/09/2010 |
| 20100311178 | Labelled nucleotides The invention provides a nucleotide or nucleoside having a base attached to a detectable label via a cleavable linker, characterised in that the cleavable linker contains a moiety selected from the group comprising: Formula (I) (wherein X is selected from the group comp... | 12/09/2010 |
| 20100303937 | NOVEL COMPOSITION TO INCREASE TESTOSTERONE LEVELS The present invention relates to a composition for increasing testosterone physiological levels comprising: a) a sufficient amount of at least one aromatase inhibitor chosen from a flavone substituted with at least one methoxy group at position 3′,4′,5 or 7, any com... | 12/02/2010 |
| 20100298300 | TRIAZOLOPYRAZINE COMPOUNDS USEFUL FOR THE TREATMENT OF DEGENERATIVE & INFLAMMATORY DISEASES Novel [1.2.4]triazolo[1,5-a]pyrazine compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention ... | 11/25/2010 |
| 20100298285 | Biclycloheteroaryl Compounds as P2x7 Modulators and Uses Thereof Bicycloheteroaryl compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including b... | 11/25/2010 |
| 20100298232 | Peptides targeting TNF family receptors and antagonizing TNF action, compositions, methods and uses thereof The present invention provides modulators of TNF, particularly peptides and their derivatives, particularly GEP peptides, which antagonize TNF and TNF-mediated responses, activity or signaling. The invention provides methods of antagonizing TNF and the modulation of TNF... | 11/25/2010 |
| 20100294702 | Physically and chemically emulsified hydrocarbon waters separator for ship's bilges A separator for use in ships' bilges capable of physical and chemical separation of both free and emulsified hydrocarbons from a water stream that includes two separation units, the first one being a gravimetric separation unit that utilizes coalescent plates to separat... | 11/25/2010 |
| 20100292452 | Modified nucleotides The invention provides modified nucleotide or nucleoside molecule comprising a purine or pyrimidine base and a ribose or deoxyribose sugar moiety having a removable 3′-OH blocking group covalently attached thereto, such that the 3′ carbon atom has attached a group o... | 11/18/2010 |
| 20100292235 | Bicycloheteroaryl Compounds as P2x7 Modulators and Uses Thereof Bicycloheteroaryl compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a ... | 11/18/2010 |
| 20100286182 | HYDRAZIDE COMPOUNDS AS THYROID HORMONE RECEPTOR MODULATORS AND USES THEREOF A method of identification of compounds that modulate thyroid hormone activity, and the use of such compounds and compositions thereof for such purposes are disclosed. The compounds may be selected from the group consisting of: | 11/11/2010 |
| 20100285017 | MATRIPTASE PROTEIN AND USES THEREOF The present invention provides methods and compositions for treatment, screening, diagnosis, prognosis and therapy of breast cancer, colorectal cancer, esophageal cancer, gastric cancer, prostate cancer and uterine cancer, for monitoring the effectiveness of breast canc... | 11/11/2010 |
| 20100284918 | PROTEIN The present invention provides methods and compositions for treatment, screening, diagnosis and prognosis of breast cancer, colorectal cancer, gastric cancer, hepatocellular carcinoma, lung cancer and pancreatic cancer, for monitoring the effectiveness of breast cancer,... | 11/11/2010 |
| 20100284908 | PROTEINS The present invention provides new polypeptides. Said polypeptides are of use in the screening, diagnosis and prognosis of B-cell non-Hodgkin's lymphoma, breast cancer, colorectal cancer, gastric cancer, hepatocellular carcinoma, lung cancer, lymphoid leukaemia (particu... | 11/11/2010 |
| 20100273662 | Method of preparing libraries of template polynucleotides The present invention relates to a method for preparing a library of template polynucleotides and use thereof in methods of solid-phase nucleic acid amplification. More specifically, the invention relates to a method for preparing a library of template polynucleotides t... | 10/28/2010 |
| 20100267618 | Methods for treating congestive heart failure The invention features methods of treating or preventing congestive heart failure by administering a polypeptide containing an epidermal growth factor-like domain encoded by a neuregulin gene.... | 10/21/2010 |
| 20100266986 | One piece angled abutment The present invention refers to a one-piece angled abutment (5) comprising an abutment stump (6) for affixing a prosthetic dental piece to said abutment stump and a lower threaded portion (4), wherein the threading means consist of the lower threade... | 10/21/2010 |
| 20100261005 | Method of preparing metallic nanoparticles and materials thus obtained The invention relates to a method of preparing metallic nanoparticles and to the materials thus obtained. More specifically, the invention relates to a method of preparing metallic nanoparticles consisting in: selecting a precursor from the salts, hydroxides and oxides ... | 10/14/2010 |
| 20100258503 | DIALYSATE REGENERATION UNIT A dialysate regeneration unit adapted for regenerating a dialysate containing carrier substances comprises a first flow path and a second flow path. The first flow path comprises a first supply unit adapted for adding an acidic fluid to the dialysate flowing in the firs... | 10/14/2010 |
| 20100247657 | TELOMERASE REVERSE TRANSCRIPTASE VARIANT The present invention relates to nucleic and amino acid sequences of a novel variant of the telomerase reverse transcriptase. More particularly, the present invention is directed to a novel variant of human telomerase reverse transcriptase, which displays properties dis... | 09/30/2010 |