"It is my heart-warmed and world-embracing Christmas hope and aspiration that all of us, the high, the low, the rich, the poor, the admired, the despised, the loved, the hated, the civilized, the savage (every man and brother of us all throughout the whole earth), may eventually be gathered together in a heaven of everlasting rest and peace and bliss, except the inventor of the telephone. "
Mark Twain ; Christmas greetings, 1890
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| Application No. | Application Title | Issue Date |
| 20110015212 | PYRIMIDINONES AS PI3K INHIBITORS The present invention provides pyrimidinones that modulate the activity of phosphoinositide 3-kinases (PI3Ks) and are useful in the treatment of diseases related to the activity of PI3Ks including, for example, inflammatory disorders, immune-based disorders, cancer, and... | 01/20/2011 |
| 20100306854 | Generating Obfuscated Data A method for obfuscating data includes: reading values occurring in one or more fields of multiple records from a data source; storing a key value; for each of multiple of the records, generating an obfuscated value to replace an original value in a given field of the r... | 12/02/2010 |
| 20100305983 | Providing Travel Information Using Cached Query Answers Systems and techniques for presenting travel information to a user are described. A code that includes predetermined travel parameters specified by the user is included in a web page. Access to the web page by a user is detected. A travel query is populated with the pre... | 12/02/2010 |
| 20100305578 | Uterine Manipulators and Related Components and Methods A uterine manipulator tip includes a finger and an expandable member. The finger is configured to be confined within a cervix. The expandable member is carried by the finger and is configured to engage a cervical canal between an internal cervical os and an external cer... | 12/02/2010 |
| 20100305496 | FLOW LIMITER FOR A FLUID FLOWING IN AN ASPIRATION BRANCH OF A SURGICAL SYSTEM, AND SURGICAL SYSTEM The invention relates to a flow limiter (8) for a fluid flowing in an aspiration branch of a surgical system. which fluid is a surgical fluid and has emulsified particles in a surgical intervention, with a limiter element (81) that comprises at least one f... | 12/02/2010 |
| 20100305433 | NON-CONTACT CARDIAC MAPPING, INCLUDING RESOLUTION MAP A non-contact cardiac mapping method is disclosed that includes: (i) inserting a catheter into a heart cavity having an endocardium surface, the catheter including multiple, spatially distributed electrodes; (ii) measuring signals at the catheter electrodes in response ... | 12/02/2010 |
| 20100305308 | Lactoferrin A pure lactoferrin polypeptide containing no more than two metal ions per molecule, or a mixture of the polypeptide and a fragment thereof. The polypeptide or the mixture stimulates skeletal growth and inhibits bone resorption. Also disclosed is a method of treating a b... | 12/02/2010 |
| 20100304401 | YS68 GENE INVOLVED IN PRIMITIVE HEMATOPOIESIS A novel gene, dubbed “YS68”, involved in primitive hematopoiesis was successfully isolated from cDNA derived from mouse yolk sacs. In addition, a human gene corresponding to this gene was successfully isolated. Expression characteristics of these genes suggested the... | 12/02/2010 |
| 20100304371 | COMPOSITIONS AND METHODS FOR DETECTING MYCOBACTERIA The present invention features compositions and methods that can be used to analyze samples for the presence of mycobacterium from MTC, M. bovis and M. tuberculosis. Moreover, the methods can be used, for example, to differentiate M. bovis fr... | 12/02/2010 |
| 20100303105 | GENERATING PULSE TRAINS IN Q-SWITCHED LASERS The invention relates to methods and systems for generating a pulse train having several individual pulses, wherein the individual pulses have a desired pulse characteristic, by means of a Q-switched solid state laser system, which includes, e.g., a modulator for influe... | 12/02/2010 |
| 20100302976 | Front-End Circuit A front-end circuit for a mobile radio includes a first Frequency Division Duplexing (FDD) transmission path for a first FDD mobile radio system, where the first FDD transmission path includes a transmission amplifier and a duplexer that includes a transmission filter e... | 12/02/2010 |
| 20100302546 | OPTICAL MEASUREMENT OF SAMPLES A portable device includes a base unit, an extension, and a mirror. The base unit includes a light source, a light detector, and at least one window through which light exits from, and is received by, the base unit. The extension is configured, during use, to be attache... | 12/02/2010 |
| 20100300766 | Convex Crested Insert With Deflected Wedge Surfaces This invention relates to carbide inserts used on roller cone bits for oil and gas drilling applications as well as for other geological drilling applications, and more specifically, relates to the convex crested insert with deflected wedge surfaces. The insert comprise... | 12/02/2010 |
| 20100299149 | Character Models for Document Narration Disclosed are techniques and systems to provide a narration of a text in multiple different voices where the portions of the text narrated using the different voices are selected by a user. Also disclosed are techniques and systems for associating characters with portio... | 11/25/2010 |
| 20100298582 | Intermediate Compounds and Processes for the Preparation of 7-benzyloxy-3-(4-methoxyphenyl)-2H-1-benzopyran Disclosed herein is a compound of formula (I): wherein:
| 11/25/2010 |
| 20100298581 | Processes for Preparing Isoflavonoids using 7-benzyloxy-3-(4-methoxyphenyl)-2H-1-benzopyran as a Starting Material Disclosed herein are processes for the preparation of isoflavonoids, in particular haginin E, equol, daidzein, formononetin and the like, in which 7-benzyloxy-3-(4-methoxyphenyl)-2H-1-benzopyran is used as a common starting material.... | 11/25/2010 |
| 20100298542 | Modified Antibody Constant Region The present inventors succeeded in improving the antibody constant region to have increased stability under acid conditions, reduced heterogeneity originated from disulfide bonds in the hinge region, reduced heterogeneity originated from the H chain C terminus, and incr... | 11/25/2010 |
| 20100298355 | 3-[4-(7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)-1H-PYRAZOL-1-YL]OCTANE- OR HEPTANE-NITRILE AS JAK INHIBITORS The present invention relates to the Janus kinase (JAK) inhibitors 3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]octanenitrile or 3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]heptanenitrile, as well as its compositions and methods of use, which is use... | 11/25/2010 |
| 20100298334 | N-(HETERO)ARYL-PYRROLIDINE DERIVATIVES OF PYRAZOL-4-YL-PYRROLO[2,3-d]PYRIMIDINES AND PYRROL-3-YL-PYRROLO[2,3-d]PYRIMIDINES AS JANUS KINASE INHIBITORS The present invention relates to N-(hetero)aryl-pyrrolidine derivatives of Formula I: which are JAK inhibitors, such as selective JAK1 inhibitors, useful in the treatment of JAK-associated diseases including,... | 11/25/2010 |
| 20100297684 | ACTIVATIBLE DYES Novel, activatable dyes, such as photoactivatable dyes, e.g., oxazine dyes, are described. Some of the dyes are targeting dyes that can, e.g., target biomolecules, such as polypeptides, proteins, or nucleic acids. Upon activation, such as by irradiation, the novel dyes ... | 11/25/2010 |
| 20100297651 | Methods of Modulating Vesicular Trafficking Described are methods of identifying compounds useful for modulating vesicular trafficking, particularly those that disrupt the interactions between ARNO and the V-ATPase a2-subunit. Also described are peptides that modulate vesicular trafficking.... | 11/25/2010 |
| 20100297362 | METHOD FOR PROCESSING AN OBJECT WITH MINIATURIZED STRUCTURES A method for processing an object with miniaturized structures is provided. The method includes feeding a reaction gas onto a surface of the object. The method also includes processing the object by directing an energetic beam onto a processing site in a region, which i... | 11/25/2010 |
| 20100297298 | MEAL REPLACEMENT BEVERAGE Meal replacement compositions are described herein. The meal replacement compositions are made using all natural ingredients and includes relatively high amounts of fiber and protein and relatively low amounts of fat. In some instances, a single serving of a meal replac... | 11/25/2010 |
| 20100296546 | OPTICAL GUIDE WITH TEMPERATURE SENSING MATRIX The invention relates to an optical element for guiding and forming a laser beam, and to a method for recording beam parameters, particularly in a laser system, comprising a carrier substrate (40) and a coating (39), which is applied to at least one side o... | 11/25/2010 |
| 20100296085 | RAMAN SPECTROMETRY ASSEMBLY A Raman spectrometry assembly includes a Raman spectrometer having a laser light source and a Raman signal analyzer, an interface module comprising a housing which is connectable to and disconnectable from the spectrometer, and a fiber optic assembly which is connectabl... | 11/25/2010 |
| 20100294930 | SCANNING CHARGED PARTICLE BEAMS Methods are disclosed that include exposing, in direct succession, portions of a surface of a sample to a charged particle beam, the portions of the surface of the sample forming a row in a first direction, the charged particle beam having an average spot size fat the s... | 11/25/2010 |
| 20100293802 | Multiple Display Electronic Caliper In addition to other aspects disclosed, a caliper is configured to measure at least one physical dimension. The caliper has a display configured to present a first representation and a second representation of a measurement provided by the caliper. The format of the fir... | 11/25/2010 |
| 20100293487 | Provider-to-provider Consultations Amongst other things, a computer-implemented method comprises receiving, by one or more computers, data indicating that a first service provider is authorized to engage in a consultation with a second service provider; and receiving, by one or more computers, a request ... | 11/18/2010 |
| 20100293007 | Provider Decision Support A computer-implemented method is described for retrieving, from a data repository that stores decision support information, decision support information pertinent to a consumer of services with whom a service provider is engaged in a real-time consultation; and generati... | 11/18/2010 |
| 20100292776 | Bioerodible Endoprosthesis A stent includes a first tubular element formed of a first bioerodible metal composition and second tubular element formed of a second biodegradable metal composition. The first and second tubular elements are concentrically arranged; and the first and second bioerodibl... | 11/18/2010 |
| 20100292606 | Signal Processing in Physiological Noise The invention relates to systems and methods for estimating a response of at least a part of a physiological system to a first deterministic stimulus signal. The methods include separating a measured first signal into a plurality of segments, each segment representing a... | 11/18/2010 |
| 20100292374 | CROSSLINKED POLYMERS AND METHODS OF MAKING THE SAME Methods are described that include elongating, e.g., by stretching and/or compressing, a polymeric material, such as an ultra-high molecular weight polyolefin (e.g., an ultra-high molecular weight polyethylene (UHMWPE)), below, or above a melt temperature of the polymer... | 11/18/2010 |
| 20100292238 | Phenoxymethyl Heterocyclic Compounds Phenoxymethyl compounds that inhibit at least one phosphodiesterase 10 are described as are pharmaceutical compositions containing such compounds an methods for treating various CNS disorders by administering such compounds to a patient in need thereof.... | 11/18/2010 |
| 20100292052 | Exercising Apparatus An apparatus is disclosed for enabling an operator to exercise comprising a frame having a body, a base and a top. A load is positioned on the frame for providing a resistive force. A press is positioned on the frame for displacement by the operator. A linkage joins the... | 11/18/2010 |
| 20100291577 | Toll-Like Receptor 9 Modulators TLR9 is localized to endoplasmic reticulum and upon stimulation with a TLR9 ligand, is transported to a tubular lysosomal compartment as is CpG-DNA. Furthermore, it is shown that TLR9 and CpG-DNA directly bind. It was also found that the MyD88 translocates in response t... | 11/18/2010 |
| 20100291568 | METHODS FOR GENETIC ANALYSIS OF DNA TO DETECT SEQUENCE VARIANCES Methods for determining genotypes and haplotypes of genes are described. Also described are single nucleotide polymorphisms and haplotypes in the ApoE gene and methods of using that information.... | 11/18/2010 |
| 20100291506 | DEVICE FOR DEBRIDEMENT OF IMPLANTS, AND A METHOD FOR DEBRIDEMENT OF IMPLANTS USING THE DEVICE A device (10) for debridement of dental implants, which are arranged into bone tissue and are surrounded by gingiva of a jaw of a human being, has a debriding element (11) and an axle (12) with a fastener (13) for attachment to a rotational a... | 11/18/2010 |
| 20100290520 | SELECTING TRANSFORMS FOR COMPRESSING VISUAL DATA Encoding data includes: computing a first set of coefficients based on a plurality of transforms each computed over a different portion of an array of data, and a second set of coefficients based on a transform computed over the array of data; choosing a set of coeffici... | 11/18/2010 |
| 20100290389 | Multi-carrier System Selection In general, a method performed on a personal base station includes transmitting a first pilot signal to a portable access terminal operating in an idle mode in a macrocell that uses a first carrier frequency. The first pilot signal is transmitted in the first carrier fr... | 11/18/2010 |
| 20100290042 | Use of Free-space Coupling Between Laser Assembly, Optical Probe Head Assembly, Spectrometer Assembly and/or Other Optical Elements for Portable Optical Applications Such as Raman Instruments An apparatus includes: a handheld Raman analyzer that can include: a common platform; a laser assembly mounted on a laser platform, the laser platform supported on the common platform by a first material and a second thermally conductive material wherein the first mater... | 11/18/2010 |