U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Icon_funbox Bizarre Patents

Patent No. 5265827

Paddle Wheel Plane

An aircraft having vertical takeoff and landing capability provided with at least first and second laterally extending paddle wheels rotatable on a central axis perpendicular to the longitudinal axis of the aircraft fuselage and between its nose and tail.

Newsletter  PatentStorm News

Make the Most of Our Site

See this month's Top Inventors and Most Cited Patents.

Stay on top of the latest innovations by subscribing to an RSS feed.

Registered users: Manage your profile.

 

Attorney: DLA Piper LLP (US)


Number of applications: 260
Last date: February 24, 2011

1              
Application No.Application TitleIssue Date
20110046058COMPOSITIONS FOR ENTERAL ABSORPTION AND SUSTAINED ACTION OF LEPTIN-RELATED PEPTIDES USEFUL IN THE TREATMENT OF OBESITY AND LEPTIN-MODULATED DISEASE
The invention relates generally to enterally absorbed peptide compositions and more specifically to leptin-related peptide compositions, methods of administration, and methods of modulating the speed and sustained action of systemic absorption of such peptides useful in...
02/24/2011
20110045018ASTROVIRUS SPECIES
Provided herein are sequences of the genomes and encoded proteins of new astrovirus species, and variants thereof. Also provided are methods of detecting the new astrovirus species and diagnosing astrovirus infection, methods of treating or preventing astrovirus infecti...
02/24/2011
20110039770INHIBITORS OF PROTEIN KINASE C ISOFORMS AND USES THEREOF
Inhibitors of mammalian protein kinase C isoforms that comprise an inhibitor moiety, which is capable of inhibiting protein kinase activity, operatively associated with a peptide recognition element (PRE), which has an affinity for one or more PKC isoforms are provided....
02/17/2011
20110039335Compositions and Methods for Inhibiting Cell Migration
The finding that Dickkopf1 (Dkk1) is a dual function protein demonstrates a mechanism for the coordination of cell migration and antagonism of Wnt/β-catenin signaling during developmental and pathological processes. The profile of Dkk proteins expressed by human breast...
02/17/2011
20110034686Process for Isolation and Purification of Geldanamycin
The present invention is successful in providing a suitable process for the isolation and purification of geldanamycin. The process provided in the instant invention is easy to scale-up, industrially safe and will give high yield and productivity....
02/10/2011
20110034685Method for Purification of Lactose
The present invention relates to improved methods of purification of sugars and in particular to a method of preparing lactose. A low purity lactose source such as whey is subjected to a first demineralization step involving either ion-exchange or the addition of divale...
02/10/2011
20110034678METHODS OF RENATURATION OF RECOMBINANT PROTEINS
The present invention provides large-scale methods for renaturation of proteins comprising adding a solution of denatured, chemically modified or reduced proteins to a refolding buffer containing sulfate derived from H2SO4 and/or MgSO4 i...
02/10/2011
20110034372TRUNCATED ACTIVIN TYPE II RECEPTOR AND METHODS OF USE
The present invention provides a substantially purified growth differentiation factor (GDF) receptor, including a GDF-8 (myostatin) receptor, as well as functional peptide portions thereof. In addition, the invention provides a virtual representation of a GDF receptor o...
02/10/2011
20110031986Sub-Threshold Capfet Sensor for Sensing Analyte, A Method and System Thereof
The present invention relates to high sensitivity chemical sensors, more particularly relates to high sensitivity chemical sensors which are capacitively coupled, FET based analyte sensors. A sub-threshold capacitively coupled Field Effect Transistor (CapFET) sensor for...
02/10/2011
20110028702COMPOSITIONS AND PROCESSES FOR PREPARING 13-DEOXY-ANTHRACYCLINES
13-benzenesulfonylhydrazone anthracyclines useful in producing improved yields in the synthesis 13-deoxyanthrcyclines, and an improved method of reducing 13-benzene-sulfonylhydrazone anthracyclines to 13-deoxyanthrcyclines wherein the reduction reaction is maintained at...
02/03/2011
20110027797Method for the Diagnosis of Higher- and Lower-Grade Astrocytoma Using Biomarkers and Diagnostic Kit Thereof
Disclosed is a method of diagnosing the presence of higher grade astrocytoma/glioblastoma (GBM) or lower-grade grade astrocytoma (DA or AA) in a human subject using secreted or plasma membrane associated biomarkers, which involves the detection of the expression levels ...
02/03/2011
20110027379Oligo-Ethylene Glycol-Based Polymer Compositions and Methods of Use
The invention provides biodegradable PEAs, PEURs and PEUs that are synthesized by solution polycondensation to include α-amino acids and oligo-ethylene ether segments in the polymer backbone. The polymers can be obtained by substituting oligo-ethylene glycol (OEG) for ...
02/03/2011
20110025725BACKLIGHT UNIT AND CONTROL METHOD FOR THE SAME
A backlight unit for a display device and a control method for the same is presented. The backlight unit comprises: a plurality of light source units arranged in a matrix form; a light source controller adapted to supply a control signal for controlling a brightness of ...
02/03/2011
20110020807Methylated CpG Island Amplification (MCA)
The present invention provides a method for identifying a methylated CpG containing nucleic acid by contacting a nucleic acid with a methylation sensitive restriction endonuclease that cleaves unmethylated PcG sites and contacting the sample with an isoschizomer of the ...
01/27/2011
20110020435STABILIZING ALKYLGLYCOSIDE COMPOSITIONS AND METHODS THEREOF
The present invention relates to alkylglycoside-containing compositions and methods for increasing the stability, reducing the aggregation and immunogenicity, increasing the biological activity, and reducing or preventing fibrillar formation of insulin or an analog ther...
01/27/2011
20110020433COMPOSITIONS FOR DELIVERY OF CARGO SUCH AS DRUGS PROTEINS AND/OR GENETIC MATERIALS
Compositions and methods for delivery of cargo molecules to a patient or subject in need thereof include a proteoliposome carrier vehicle that incorporates an RLIP76 protein and contains the cargo molecule. The vehicle effectively delivers the cargo molecule systemicall...
01/27/2011
20110020432COMPOSITIONS AND METHODS OF USE FOR POST-RADIATION PROTECTION
The present disclosure is directed to methods of administering RL1P76 or an active fragment thereof more than 24 hours after radiation exposure, wherein administration is effective for the protection and treatment of mammals exposed to radiation. In addition, compositio...
01/27/2011
20110019083Frame-Rate Conversion
A method of generating presentation time stamps, PTSs, for motion-compensated frame-rate conversion of a sequence of frames. In one aspect, the method comprises for each new frame: determining an average difference between the capture time-stamps of recent consecutive n...
01/27/2011
20110015447Process for the Preparation of Primary Alkyl Glycerol Ethers Useful as Biofuel Additive from Glycerol
The present invention provides a process for the preparation of biofuels or biofuel additives from glycerol. More particularly, it provides a process for the preparation of glycerol-ethers by etherification of glycerol with an alcohol in the presence of solid acid catal...
01/20/2011
20110014664 Fermentation Process for Higher Yield Coefficient of Lipase-Inhibitor with Respect to Consumed Fatty Acid
The invention provides a process for the production of lipase inhibitors via an improvised fermentation process characterized in that a combinatorial feeding of linoleic acid or its esters or salts thereof and an omega-9 fatty acid, preferably oleic acid and/or its deri...
01/20/2011
20110014204Cancer Chemoprevention Strategy Based on Loss of Imprinting of IGF2
The present invention relates to targets of loss of imprinting (LOI) affected IGF2 gene products in pre-malignant tissues, where methods of inhibiting those targets, including IGFR1, are disclosed to prevent tumor development in subjects at risk for developing colorecta...
01/20/2011
20110008842NOVEL CHIMERIC TNF LIGANDS
The present invention is directed to an isolated polynucleotide sequence encoding a chimeric TNFα, comprising a first nucleotide sequence encoding a domain or subdomain of a tumor necrosis factor ligand other than TNFα, wherein the encoded domain or subdomain replaces...
01/13/2011
20110005977DEVICE AND METHOD FOR SINGLE STREAM RECYCLING OF HAZARDOUS MATERIALS
The present invention provides devices and methods for facilitating the single stream recycling of toxic substance-containing products. A toxin impermeable container designed to enclose the product containing toxic substances incorporates graphic markings or radiofreque...
01/13/2011
20110005523Pharmaceutical Polypeptide Dry Powder Aerosol Formulation and Method of Preparation
Dispersible powder compositions suitable for inhalation are disclosed, the compositions including a human interleukin mutein (mhIL-4)....
01/13/2011
20110003284Aberrantly Methylated Genes in Pancreatic Cancer
The present invention provides a method for detecting pancreatic carcinoma in a subject. The method includes contacting a nucleic acid-containing specimen from the subject with an agent that provides a determination of the methylation state of at least one gene or assoc...
01/06/2011
20110002941Antibodies that Specifically Bind Hedgehog-Derived Polypeptides
The present invention provides two novel polypeptides, referred to as the “N” and “C” fragments of hedgehog, or N-terminal and C-terminal fragments, respectively, which are derived after specific cleavage at a G′CF site recognized by the autoproteolytic domain...
01/06/2011
20110002939 MONOCLONAL ANTIBODY AND A METHOD THEREOF
The present invention relates to a humanized IgG1 isotype anti-CD6 antibody (T1h) that binds to the Scavenger receptor cysteine-rich (SRCR) domain 1(D1) of CD6 present on the surface of thymic epithelial cells, monocytes, activated T cells and a variety of other cells t...
01/06/2011
20100331279Inhibition of Antigen Presentation with Poorly Catabolized Polymers
Methods to prevent the rejection of immunogenic tissues in an animal by administering a non-immunogenic, poorly catabolized molecule in an amount sufficient to inhibit an immune response are described herein. Also described are compositions that are useful for inhibitin...
12/30/2010
20100330594Early Detection of Diabetes
The present invention is based on the discovery that hexosamine, and in particular the dynamic O-GlcNAcylation of proteins (modification of proteins by the sugar N-acetylglucosamine) both causes insulin-resistance (a hallmark of type II diabetes) and is responsible for ...
12/30/2010
20100329346Determining a vector field for an intermediate image
The invention relates to a method for generating a motion vector field for an intermediate image disposed between a first and a second image....
12/30/2010
20100328527Fast Channel Switch Between Digital Television Channels
The invention relates to a method for outputting a first digital video stream (BTS′). The method comprises: i) receiving a first transport stream (TS1) comprising a first plurality of time-multiplexed video channels (SRV1, SRV2, SRV3, SRV
12/30/2010
20100317007Methods and Systems to Identify Operational Reaction Pathways
The present invention provides a method for identifying an operational reaction pathway of a biosystem. The method includes (a) providing a set of systemic reaction pathways through a reaction network representing said biosystem; (b) providing a set of phenomenological ...
12/16/2010
20100315560Image Processing Method With Motion Estimation And Image Processing Arrangement
A method for processing a video image sequence with a number of successive images and an image processing device for processing a video image sequence are described. The method comprises:
    12/16/2010
    20100305129COMPOSITIONS AND METHODS FOR INHIBITING GROWTH AND METASTASIS OF MELANOMA
    There are provided methods of inhibiting growth and metastasis of melanoma, methods of sensitizing melanoma cells to apoptosis, and methods of treating a subject having melanoma using acetyl isogambogic acid, celastrol, or a derivative thereof. There are further provide...
    12/02/2010
    20100305121NOVEL ANTAGONISTS OF THE HUMAN FATTY ACID SYNTHASE THIOESTERASE
    The present invention provides for compounds of formula (I)-(XIII), as well as pharmaceutically acceptable salts thereof, metabolites thereof, pro-drugs thereof, and pharmaceutical kits that include such compounds. The present invention also provides for the compounds o...
    12/02/2010
    20100304471ASSAY
    The present invention relates to test devices, and in particular devices capable of detecting the presence or absence of an analyte in a sample, such as a liquid sample. Also provided are methods of using such devices for quantitative or qualitative measurement of one o...
    12/02/2010
    20100297695Nucleic Acids Encoding Chimeric CD154 Polypeptides
    The present invention provides for an isolated polynucleotide sequence encoding a chimeric CD154, comprising a first nucleotide sequence encoding an extracellular subdomain of non-human CD154, preferably murine CD154, that replaces a cleavage site of human CD154, and a ...
    11/25/2010
    20100297655SOCS-1 GENE METHYLATION IN CANCER
    Methods are provided for identifying a cell exhibiting unregulated growth associated with methylation-silenced transcription of a suppressor of cytokine signaling (SOCS)/cytokine-inducible SH2 protein (CIS) family member (SOCS/CIS) gene such as the SOCS-1 gene. In addit...
    11/25/2010
    20100297179Immunology Treatment for Biofilms
    The invention provides a composition for use in raising an immune response to P. gingivalis in a subject, the composition comprising an amount effective to raise an immune response of at least one polypeptide having an amino acid sequence substantially identical ...
    11/25/2010
    20100292498Site-Specific Inhibitors of Histone Methyltransferase [HMTASE] and Process of Preparation Thereof
    The present invention relates to compounds of structural formula (I) as site-specific inhibitor of histone methyl-transferase, where R1 and R1 is —OCH or —OH, R2 and R2 is —OH or —OAc; a process of isolating compound o...
    11/18/2010
    1              
     
    Sign InRegister
    Username  
    Password   
    forgot password?