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| Application No. | Application Title | Issue Date |
| 20090131414 | PYRIDO(3,2-D)PYRIMIDINES AND PHARMACEUTICAL COMPOSITIONS USEFUL FOR TREATING HEPATITIS C Specifically substituted pyrido(3,2-d)pyrimidine derivatives having the structural formula (I) are useful for the treatment of hepatitis C.... | 05/21/2009 |
| 20090130724 | Enzymatic Demethylation of Flavonoids The invention discloses the demethylation of 5-methoxyflavonoids by bacterial enzymes, the use of these enzymes in the production of phytoestrogens in vitro, and in pharmaceutical compositions in combination with a source of methylated 5-methoxyprenylflavonoids.... | 05/21/2009 |
| 20090124664 | (R)-Arylalkylamino Derivatives and Pharmaceutical Compositions Containing Them The present invention relates to selected (R)-arylalkylamino derivatives of formula (I), in which R, R1 and Ar are as defined in the claims. These compounds show a surprising potent inhibitory effect on C5a induced human PMN chemotaxis. The compounds of the invention ab... | 05/14/2009 |
| 20090123976 | Compositions and Method for Storage of Nucleic Acid From Bodily Fluids An aqueous composition comprising a denaturing agent, a chelator, a buffering agent and a protease for the extraction of nucleic acid from a sample of bodily fluid, such as saliva, such that the extracted nucleic acid is stable for at least fourteen days at room tempera... | 05/14/2009 |
| 20090123927 | ISOLATION OF PRECURSOR CELLS AND THEIR USE FOR TISSUE REPAIR Cartilage-derived morphogenetic protein CDMP-1 or a transforming growth factor β having at least 80% homology with CDMP-1, or a factor co-expressed and/or co-detectable therewith, is used as a marker of skeletal precursor cells from any part of a mammalian body.... | 05/14/2009 |
| 20090120874 | MEMBRANE FOR FILTERING OF WATER Disclosed are novel water membranes comprising lipid bilayers incorporating functional aqua-porins. The lipid bilayers are arranged in sandwich structures including hydrophilic or hydro-phobic support materials. Also disclosed are water purification devices/systems, inc... | 05/14/2009 |
| 20090118132 | Classification of Acute Myeloid Leukemia The present invention relates to rapid and reliable approaches to leukemia prognostication. In addition to methods, the invention also provides related kits and systems.... | 05/07/2009 |
| 20090117652 | USE OF CXCL6 CHEMOKINE IN THE PREVENTION OR REPAIR OF CARTILAGE DEFECTS The present invention disclosed the expression of CXCL6 by cells which are able to form stable cartilage. The invention describes the use of these cells and of CXCL6 to promote cartilage (and underlying bone) formation e.g. in the repair of cartilage or osteochondral de... | 05/07/2009 |
| 20090117618 | Expression system for preparing IL-15/FC fusion protein and its use The invention relates to an expression system containing one or more nucleic acid(s) comprising at least one nucleic acid for an interleukin 15/Fc (IL-15/Fc) fusion protein, at least one promotor, at least one nucleic acid for a CD5 leader and, where appropriate, at lea... | 05/07/2009 |
| 20090117588 | Methods of diagnosing pre-eclampsia or eclampsia Disclosed herein are kits for diagnosing pre-eclampsia and eclampsia or a propensity to develop pre-eclampsia or eclampsia that include agents for the detection of levels of free placental growth factor in a subject.... | 05/07/2009 |
| 20090117185 | 2-(Aminomethyl)-5-Chlorobenzylamide Derivatives and their use as Inhibitors of the Clotting Factor Xa The invention relates to 2-(aminomethyl)-5-chlorobenzylamide derivatives and their use as inhibitors of coagulation factor Xa. The compounds are suitable for the treatment and prophylaxis of cardiovascular and thrombotic events.... | 05/07/2009 |
| 20090109518 | IMAGING APPARATUS WITH A PLURALITY OF SHUTTER ELEMENTS An apparatus for imaging an object comprises a plurality of shutter elements (601, 606, 614) and a sensor (603, 608, 612), each shutter element (601, 606, 614) being operable to control (602, 609, 613) passage of light from a separate spatial... | 04/30/2009 |
| 20090105455 | Purified interleukin-15/fc fusion protein and preparation thereof The present invention relates to a process for purifying an interleukin-15/Fc fusion protein from a composition, which process comprises a) applying the composition to an affinity chromatography column and eluting a first IL-15/Fc eluate from the column and b) applying ... | 04/23/2009 |
| 20090104285 | Methods and Compositions for Use in Treating Cancer The invention provides methods and compositions for use in treating diseases associated with excessive cellular proliferation, such as cancer.... | 04/23/2009 |
| 20090103099 | INTEGRATED SURFACE MODE BIOSENSOR An optical detection system (100) for detecting biological, chemical or bio-chemical particles is described. The optical detection system (100) typically comprises a surface mode interference means. The surface mode interference means may comprise a layer ... | 04/23/2009 |
| 20090099242 | Heterocyclic inhibitors of necroptosis The invention features a series of heterocyclic derivatives that inhibit tumor necrosis factor alpha (TNF-α) induced necroptosis. The heterocyclic compounds of the invention are described by Formulas (I) and (Ia)-(Ie) and are shown to inhibit TNF-α induced necroptosis... | 04/16/2009 |
| 20090099084 | Treatment The invention provides use of a TSG-6 polypeptide, or a polynucleotide encoding an TSG-6 polypeptide, in the manufacture of a medicament for the treatment or prevention of a bone disease or condition associated with bone resorption by osteoclasts.... | 04/16/2009 |
| 20090098650 | COMPOSITIONS FOR THE IN VITRO DERIVATION AND CULTURE OF EMBRYONIC STEM (ES) CELL LINES WITH GERMLINE TRANSMISSION CAPABILITY AND FOR THE CULTURE OF ADULT STEM CELLS The present invention describes novel compositions for deriving, maintaining and growing pluripotent and germ-line competent mammalian embryonic stem cells. The compositions of this invention refer to compositions comprising a 1) conditioned medium of a cell line expres... | 04/16/2009 |
| 20090098634 | SCLEROPROTEIN OF AN ADENO ASSOCIATED VIRUS WITH MODIFIED CHROMATOGRAPHIC PROPERTIES, THE PRODUCTION THEREOF AND USE OF THE SAME The invention relates to a scleroprotein of an adeno-associated virus which contains at least one mutation. Said mutation causes the chromatographic properties to be modified. The invention also relates to the production of said scleroprotein and the use thereof. ... | 04/16/2009 |
| 20090098105 | Treatment of neurodegenerative diseases by the use of scd4 inhibitors The present invention relates to the use of SCD4 interacting molecules, especially SCD4 inhibitors, for the preparation of a medicament for the treatment of neurodegenerative diseases, particularly Alzheimer's disease.... | 04/16/2009 |
| 20090098083 | CONJUGATE ADDITION REACTIONS FOR THE CONTROLLED DELIVERY OF PHARMACEUTICALLY ACTIVE COMPOUNDS The invention features polymeric biomaterials formed by nucleophilic addition reactions to conjugated unsaturated groups. These biomaterials may be used for medical treatments.... | 04/16/2009 |
| 20090098020 | Binding Assay A binding assay product (1) for detecting the presence of an analyte in a sample comprising a labelling module (5), a label, a capture module (9) and a visualisation module (10). The labelling module (5) comprises a first binding compo... | 04/16/2009 |
| 20090092975 | SELECTABLE MARKER A nucleic acid sequence encoding a decarboxylation enzyme E.G. PAD1 is used as a selectable marker in a recombinant organism. A weak acid is used as the selecting agent.... | 04/09/2009 |
| 20090092663 | Tumor-targeted drug delivery systems and uses thereof The present invention relates to targeted delivery systems for delivering therapeutic agents to tumor. The invention further relates to methods of delivering a therapeutic agent to a tumor for the prevention and treatment of cancer by killing tumor cells and tumor-assoc... | 04/09/2009 |
| 20090088369 | GLP-1 AND METHODS FOR TREATING DIABETES The present invention relates to use of GLP-1 or a related molecule having a GLP-effect for the manufacture of a medicament for preventing or treating diabetes in a mammal. The amount and timing of administration of said medicament are subsequently reduced to produce a ... | 04/02/2009 |
| 20090088343 | METHOD OF PATTERNING AND PRODUCT(S) OBTAINED THEREFROM The present invention provides a method of patterning, the method comprising the steps of: (a) providing a porous film; and (b) adding at least one structure to the porous film. The present invention also provides a patterned film prepared according to the method of the... | 04/02/2009 |
| 20090087859 | Microfluidic device for detecting soluble molecules The present disclosure provides a microfluidic device that is compatible with standard centrifuges and may be used for point-of-care disease detection. The detection methodology may be based on microELISA.... | 04/02/2009 |
| 20090087449 | Novel Peptide Compositions and the Use Thereof, in Particular, in the Preparation of Active Pharmaceutical Compositions Against the Hepatitis C Virus The invention relates to novel peptide compositions. In particular, the invention relates to a peptide composition comprising at least two peptides which are selected from among the following peptides: a peptide A having at least the amino acid sequence of SEQ ID NO 1, ... | 04/02/2009 |
| 20090082277 | Potentiation of anticancer agents The present invention relates to carriers, conjugate and pharmaceutical compositions and their use to increase the potency of drugs and to modify the pharmacokinetics of compounds. More particularly, the present invention relates to conjugates comprising the carrier des... | 03/26/2009 |
| 20090081238 | Anti-notch1 NRR antibodies and methods using same The invention provides anti-Notch1 NRR antibodies, and compositions comprising and methods of using these antibodies.... | 03/26/2009 |
| 20090068247 | BIOCOMPATIBLE DEVICES COATED WITH A TRIBONECTIN AND METHODS FOR THEIR PRODUCTION The present invention features biocompatible devices having a surface thereof coated with a composition that includes a tribonectin, and methods of making the devices. The tribonectin may, e.g., reduce microbial growth on or attachment to the surface of the biocompatibl... | 03/12/2009 |
| 20090068156 | TREATMENT OF MUSCULAR DYSTROPHY WITH CORD BLOOD CELLS The invention features methods for treating a patient suffering from muscular dystrophy by administration of umbilical cord blood cells, e.g., by IV infusion.... | 03/12/2009 |
| 20090041778 | Methods And Compositions For The Treatment Of Graft Failure The present invention provides methods and compositions for treating graft failure resulting from neointimal hyperplasia. These methods and compositions feature the use of platelet derived growth factor receptor (PDGFR) inhibitor compounds, such as N-phenyl-2-pyrimidine... | 02/12/2009 |
| 20090042793 | Novel Antiviral Therapies The field of the invention relates to the use of carbohydrate binding compounds as a medicine, their use to treat or prevent viral infections, their use to manufacture a medicine to treat or prevent viral infections and their use in a vaccination strategy. The present i... | 02/12/2009 |
| 20090042814 | Treatment and Diagnosis of Obligate Intracellular Pathogens This invention relates to the detection of pathogens, in particular persistent forms of obligate intracellular or membrane associated microorganisms such as Chlamydia, Mycoplasma and Ureaplasma species, in blood samples, in particular in plasma and serum s... | 02/12/2009 |
| 20090041852 | DRY POWDER COMPOSITIONS AND SYSTEMS FOR POULTRY VACCINATION This invention provides a dry powder composition for poultry vaccination via inhalation comprising an effective amount of a poultry vaccine agent, and a supporting amount of carriers for said poultry vaccine agent, said carriers comprising a combination of a reducing or... | 02/12/2009 |
| 20090041626 | INSTRUMENTATION SYSTEMS AND METHODS A device (600) for performing at least part of an analytical process comprises a communicator (605) to facilitate communication with the device, and a data handler (610) to handle data of the analytical process and/or the device. In an embodiment, t... | 02/12/2009 |
| 20090035428 | PROCESS AND DEVICE FOR DESOLVENTISING UNDER REDUCED PRESSURE The invention provides a continuous process for removing organic solvents from a marc including the steps of: continuously introducing the marc into a desolventiser; introducing an inert, gaseous stripping medium into the desolventiser; removing the organic solvents fro... | 02/05/2009 |
| 20090036430 | PYRIDO(3,2-D)PYRIMIDINES AND PHARMACEUTICAL COMPOSITIONS USEFUL FOR MEDICAL TREATMENT This invention relates to substituted pyrido(3,2-d)pyrimidine derivatives, their pharmaceutically acceptable salts, N-oxides, solvates, pro-drugs and enantiomers, possessing unexpectedly desirable pharmaceutical properties, in particular which are highly active immunosu... | 02/05/2009 |
| 20090036382 | TGF-Beta Modulators and Use Thereof The present invention relates to molecules preferably of polypeptide nature with negative regulatory activity on the amount or activity of TGF-β through direct interaction with pro-TGF-β, and containing as active region a cysteine-rich polypeptide sequence defined as ... | 02/05/2009 |
